Karsten Melcher

16.4k total citations · 6 hit papers
100 papers, 8.7k citations indexed

About

Karsten Melcher is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Plant Science. According to data from OpenAlex, Karsten Melcher has authored 100 papers receiving a total of 8.7k indexed citations (citations by other indexed papers that have themselves been cited), including 77 papers in Molecular Biology, 23 papers in Cellular and Molecular Neuroscience and 20 papers in Plant Science. Recurrent topics in Karsten Melcher's work include Receptor Mechanisms and Signaling (23 papers), Metabolism, Diabetes, and Cancer (11 papers) and Neuropeptides and Animal Physiology (10 papers). Karsten Melcher is often cited by papers focused on Receptor Mechanisms and Signaling (23 papers), Metabolism, Diabetes, and Cancer (11 papers) and Neuropeptides and Animal Physiology (10 papers). Karsten Melcher collaborates with scholars based in United States, China and Singapore. Karsten Melcher's co-authors include H. Eric Xu, Yi Jiang, X. Edward Zhou, Yan Yan, Ting-Hai Xu, Eu‐Leong Yong, Jiyuan Ke, Stephen Albert Johnston, Jun Li and M-H. Tan and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Karsten Melcher

100 papers receiving 8.6k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Amyloid beta: structure, biology and structure-based therapeutic development

2017 1.4k citations Ting-Hai Xu, Yan Yan et al. Acta Pharmacologica Sinica profile →
Androgen receptor: structure, role in prostate cancer and drug discovery

2014 650 citations H. Eric Xu, Karsten Melcher et al. Acta Pharmacologica Sinica profile →
DWARF 53 acts as a repressor of strigolactone signalling in rice

2013 649 citations Wei Yi, Lihua Zhao et al. Nature profile →
Structural basis for molecular recognition of folic acid by folate receptors

2013 582 citations Jiyuan Ke, X. Edward Zhou et al. Nature profile →
Structural insights into the lipid and ligand regulation of serotonin receptors

2021 185 citations Peiyu Xu, Sijie Huang et al. Nature profile →
Structures of the entire human opioid receptor family

2023 106 citations Youwen Zhuang, X. Edward Zhou et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Karsten Melcher	5.0k	2.1k	1.2k	1.0k	601	100	8.7k
Sovan Sarkar	6.2k 1.2×	1.2k 0.6×	2.2k 1.8×	1.5k 1.5×	656 1.1×	91	13.2k
Yuhong Zhang	11.0k 2.2×	718 0.3×	1.6k 1.3×	930 0.9×	1.0k 1.7×	79	20.9k
Timothy Haystead	8.5k 1.7×	481 0.2×	979 0.8×	608 0.6×	429 0.7×	170	11.7k
Richard A. F. Dixon	7.5k 1.5×	954 0.4×	1.6k 1.3×	2.9k 2.8×	968 1.6×	154	12.5k
Nieng Yan	9.8k 2.0×	1.8k 0.8×	799 0.7×	2.0k 2.0×	1.0k 1.7×	137	13.4k
László Vı́gh	6.0k 1.2×	1.1k 0.5×	1.1k 0.9×	357 0.3×	305 0.5×	166	8.6k
Michael Forte	9.0k 1.8×	511 0.2×	932 0.8×	2.8k 2.7×	597 1.0×	137	11.7k
Joris Winderickx	6.5k 1.3×	1.8k 0.9×	829 0.7×	675 0.7×	313 0.5×	158	8.8k
Takashi Hashimoto	10.4k 2.1×	7.1k 3.3×	755 0.6×	337 0.3×	361 0.6×	286	13.9k
Dongmei Cheng	6.1k 1.2×	654 0.3×	865 0.7×	987 1.0×	720 1.2×	184	9.4k

Countries citing papers authored by Karsten Melcher

Since Specialization

Citations

This map shows the geographic impact of Karsten Melcher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karsten Melcher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karsten Melcher more than expected).

Fields of papers citing papers by Karsten Melcher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karsten Melcher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karsten Melcher. The network helps show where Karsten Melcher may publish in the future.

Co-authorship network of co-authors of Karsten Melcher

This figure shows the co-authorship network connecting the top 25 collaborators of Karsten Melcher. A scholar is included among the top collaborators of Karsten Melcher based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Karsten Melcher. Karsten Melcher is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Schultz, Chad R., Xiaofeng Zhou, Kelly Suino-Powell, et al.. (2025). Design, Synthesis, and Biological Activity of Novel Ornithine Decarboxylase (ODC) Inhibitors. Journal of Medicinal Chemistry. 68(5). 5760–5773. 1 indexed citations

Xu, Peiyu, Sijie Huang, Chunyou Mao, et al.. (2021). Structures of the human dopamine D3 receptor-Gi complexes. Molecular Cell. 81(6). 1147–1159.e4. 57 indexed citations

Xu, Peiyu, Sijie Huang, Huibing Zhang, et al.. (2021). Structural insights into the lipid and ligand regulation of serotonin receptors. Nature. 592(7854). 469–473. 185 indexed citations breakdown →

Yan, Yan, Somnath Mukherjee, Kaleeckal G. Harikumar, et al.. (2021). Structure of an AMPK complex in an inactive, ATP-bound state. Science. 373(6553). 413–419. 74 indexed citations

Xu, Ting-Hai, Minmin Liu, X. Edward Zhou, et al.. (2020). Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B. Nature. 586(7827). 151–155. 80 indexed citations

Pinkosky, Stephen L., John W. Scott, Eric M. Desjardins, et al.. (2020). Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms. Nature Metabolism. 2(9). 873–881. 101 indexed citations

Zhuang, Youwen, Heng Liu, X. Edward Zhou, et al.. (2020). Structure of formylpeptide receptor 2-Gi complex reveals insights into ligand recognition and signaling. Nature Communications. 11(1). 885–885. 85 indexed citations

Yin, Wanchao, Zhihai Li, Mingliang Jin, et al.. (2019). A complex structure of arrestin-2 bound to a G protein-coupled receptor. Cell Research. 29(12). 971–983. 148 indexed citations

Xu, Ting-Hai, et al.. (2017). Amyloid beta: structure, biology and structure-based therapeutic development. Acta Pharmacologica Sinica. 38(9). 1205–1235. 1377 indexed citations breakdown →

10.

DeBruine, Zachary J., Jiyuan Ke, Kaleeckal G. Harikumar, et al.. (2017). Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization. Genes & Development. 31(9). 916–926. 54 indexed citations

11.

Gu, Kai, Chenghai Zhang, Xuetao Chen, et al.. (2016). Generation and characterization of a human nanobody against VEGFR-2. Acta Pharmacologica Sinica. 37(6). 857–864. 17 indexed citations

12.

Qin, Yi, Jiyuan Ke, Xin Gu, et al.. (2015). Structural and Functional Study of d-Glucuronyl C5-epimerase. Journal of Biological Chemistry. 290(8). 4620–4630. 38 indexed citations

13.

Zhi, Xiaoyong, X. Edward Zhou, Yuanzheng He, et al.. (2015). Structural basis for corepressor assembly by the orphan nuclear receptor TLX. Genes & Development. 29(4). 440–450. 20 indexed citations

14.

Zhao, Lihua, X. Edward Zhou, Wei Yi, et al.. (2015). Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3. Cell Research. 25(11). 1219–1236. 134 indexed citations

15.

Zhi, Xiaoyong, X. Edward Zhou, Karsten Melcher, & H. Eric Xu. (2015). Structures and regulation of non-X orphan nuclear receptors: A retinoid hypothesis. The Journal of Steroid Biochemistry and Molecular Biology. 157. 27–40. 9 indexed citations

16.

Wu, Zhongshan, Hao Cheng, Yi Jiang, Karsten Melcher, & H. Eric Xu. (2015). Ion channels gated by acetylcholine and serotonin: structures, biology, and drug discovery. Acta Pharmacologica Sinica. 36(8). 895–907. 48 indexed citations

17.

Ke, Jiyuan, Runze Chen, Xin Gu, et al.. (2013). Structure of a PLS-class Pentatricopeptide Repeat Protein Provides Insights into Mechanism of RNA Recognition. Journal of Biological Chemistry. 288(44). 31540–31548. 50 indexed citations

18.

West, Graham M., Bruce D. Pascal, F.-F. Soon, et al.. (2013). Protein Conformation Ensembles Monitored by HDX Reveal a Structural Rationale for Abscisic Acid Signaling Protein Affinities and Activities. Structure. 21(2). 229–235. 30 indexed citations

19.

Vashee, Sanjay, et al.. (1998). Evidence for two modes of cooperative DNA binding in vivo that do not involve direct protein–protein interactions. Current Biology. 8(8). 452–458. 58 indexed citations

20.

Melcher, Karsten & Karl‐Dieter ENTIAN. (1992). Genetic analysis of serine biosynthesis and glucose repression in yeast. Current Genetics. 21(4-5). 295–300. 34 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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