Wenzhong Yan

558 citations

19 papers · 433 indexed · h-index 12

Physiology top 10%
- Adenosine and Purinergic Signaling 4
Cellular and Molecular Neuroscience
Molecular Biology
- Receptor Mechanisms and Signaling 5
- Histone Deacetylase Inhibitors Research 4
- Pharmacological Receptor Mechanisms and Effects 3
- Signaling Pathways in Disease 3
- Protein Degradation and Inhibitors 2
Organic Chemistry
Cardiology and Cardiovascular Medicine
- Viral Infections and Immunology Research 3
Oncology
- Peptidase Inhibition and Analysis 4

Co-authors: Jianjun Cheng Liang Tan John D. McCorvy Jian Li Hualiang Jiang Jin Zhu Lei Liu Jinfeng Zhang
Cited by: Physiology Cellular and Molecular Neuroscience Molecular Biology
Partner nations: China United States Netherlands

In The Last Decade

Wenzhong Yan

19 papers receiving 423 citations

Peers

Countries citing papers authored by Wenzhong Yan

Since Specialization

Citations

This map shows the geographic impact of Wenzhong Yan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wenzhong Yan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wenzhong Yan more than expected).

Fields of papers citing papers by Wenzhong Yan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wenzhong Yan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wenzhong Yan. The network helps show where Wenzhong Yan may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Wenzhong Yan, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Wenzhong Yan Line = papers co-authored together Wenzhong Yan links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response Mingyue Yao,Wenzhong Yan,Wang Yf,Yu Zhao,Xiaowei Xu,Yujun Chen,Chengcheng Yu,Yingnian Li,Hualiang Jiang,Jie Shen,Jianjun Cheng,Chengying Xie	2025	3
2	Design and synthesis of tri-substituted pyrimidine derivatives as bifunctional tumor immunotherapeutic agents targeting both A2A adenosine receptors and histone deacetylases Ruiquan Liu,Wenwen Duan,Wenzhong Yan,Jinfeng Zhang,Jianjun Cheng	2023	8
3	Design and Synthesis of Triazole-Containing HDAC Inhibitors That Induce Antitumor Effects and Immune Response Nan Sun,Kexin Yang,Wenzhong Yan,Mingyue Yao,Chengcheng Yu,Wenwen Duan,Xiaoke Gu,Dong Guo,Hualiang Jiang,Chengying Xie,Jianjun Cheng	2023	15
4	Dual-acting antitumor agents targeting the A2A adenosine receptor and histone deacetylases: Design and synthesis of 4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine derivatives Jinfeng Zhang,Ziwei Luo,Wenwen Duan,Kexin Yang,Lijun Ling,Wenzhong Yan,Ruiquan Liu,Kurt Wüthrich,Hualiang Jiang,Chengying Xie,Jianjun Cheng	2022	11
5	Long Residence Time at the Vasopressin V₂ Receptor Translates into Superior Inhibitory Effects in Ex Vivo and In Vivo Models of Autosomal Dominant Polycystic Kidney Disease Haoran Zhang,Wenzhong Yan,Yongzhan Sun,Haoxing Yuan,Limin Su,Xudong Cao,Peng Wang,Zhou Xu,Youhui Hu,Zhongjian Wang,Yinan Wang,Kequan Fu,Ying Sun,Yupeng Chen,Jianjun Cheng,Dong Guo	2022	19
6	Optical-Controlled Kinetic Switch: Fine-Tuning of the Residence Time of an Antagonist Binding to the Vasopressin V₂ Receptor in In Vitro, Ex Vivo, and In Vivo Models of ADPKD Xiaoke Gu,Haoxing Yuan,Wenchao Zhao,Nan Sun,Wenzhong Yan,Chunyu Jiang,Yan He,Hongli Liu,Jianjun Cheng,Dong Guo	2022	10
7	Structure-Based Design of Dual-Acting Compounds Targeting Adenosine A_2A Receptor and Histone Deacetylase as Novel Tumor Immunotherapeutic Agents Wenzhong Yan,Lijun Ling,Yiran Wu,Kexin Yang,Ruiquan Liu,Jinfeng Zhang,Simeng Zhao,Guisheng Zhong,Suwen Zhao,Hualiang Jiang,Chengying Xie,Jianjun Cheng	2021	21
8	2-Phenylcyclopropylmethylamine Derivatives as Dopamine D₂ Receptor Partial Agonists: Design, Synthesis, and Biological Evaluation Wenzhong Yan,Luyu Fan,Jing Yu,Ruiquan Liu,Huan Wang,Liang Tan,Sheng Wang,Jianjun Cheng	2021	11
9	Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands Liang Tan,Qingtong Zhou,Wenzhong Yan,Jian Sun,Alan P. Kozikowski,Suwen Zhao,Xi‐Ping Huang,Jianjun Cheng	2020	16
10	Revisit ligand-receptor interaction at the human vasopressin V2 receptor: A kinetic perspective Chunji Liu,Leyi Xia,Kequan Fu,Xudong Cao,Wenzhong Yan,Jianjun Cheng,Thomas Roux,L. A. Peletier,Xiaoxing Yin,Dong Guo	2020	9
11	Tumor Immunotherapy Using A2A Adenosine Receptor Antagonists Jinfeng Zhang,Wenzhong Yan,Wenwen Duan,Kurt Wüthrich,Jianjun Cheng	2020	24
12	TSPA as a novel ATF6α translocation inducer efficiently ameliorates insulin sensitivity restoration and glucose homeostasis in db/db mice Tingting Zhou,Yanhua Cheng,Wenzhong Yan,Xiaofan Shi,Xin Xu,Jinpei Zhou,Jian Li,Jing Chen,Xu Shen	2018	5
13	Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure–Functional Selectivity Relationships (SFSRs) and Therapeutic Potential Liang Tan,Wenzhong Yan,John D. McCorvy,Jianjun Cheng	2018	101
14	Discovery of novel purine nucleoside derivatives as phosphodiesterase 2 (PDE2) inhibitors: Structure-based virtual screening, optimization and biological evaluation Xiaoxia Qiu,Yi‐You Huang,Deyan Wu,Fei Mao,Jin Zhu,Wenzhong Yan,Hai‐Bin Luo,Jian Li	2017	11
15	Identification, synthesis and pharmacological evaluation of novel anti-EV71 agents via cyclophilin A inhibition Wenzhong Yan,Jie Qing,Hanbing Mei,Junxiu Nong,Jin Huang,Jin Zhu,Hualiang Jiang,Lei Liu,Linqi Zhang,Jian Li	2015	12
16	Discovery of Novel Small Molecule Anti-HCV Agents via the CypA Inhibitory Mechanism Using O-Acylation-Directed Lead Optimization Wenzhong Yan,Jie Qing,Hanbing Mei,Fei Mao,Jin Huang,Jin Zhu,Hualiang Jiang,Lei Liu,Linqi Zhang,Jian Li	2015	16
17	Cyclophilin A Associates with Enterovirus-71 Virus Capsid and Plays an Essential Role in Viral Infection as an Uncoating Regulator Jie Qing,Yaxin Wang,Yuna Sun,Jiaoyan Huang,Wenzhong Yan,Jinglan Wang,Dan Su,Ni Cheng,Jian Li,Zihe Rao,Lei Liu,Zhiyong Lou	2014	76
18	Discovery and Optimization of 1,3,4-Trisubstituted-pyrazolone Derivatives as Novel, Potent, and Nonsteroidal Farnesoid X Receptor (FXR) Selective Antagonists Huang Huang,Ying Yu,Zhenting Gao,Yong Zhang,Chenjing Li,Xing Xu,Hui Jin,Wenzhong Yan,Ruoqun Ma,Jin Zhu,Xu Shen,Hualiang Jiang,Lili Chen,Jian Li	2012	55
19	Synthesis of 3-substituted 1,5-aldehyde estersvia an organocatalytic highly enantioselective conjugate addition of new carbonylmethyl 2-pyridinylsulfone to enals Jing Deng,Fei Wang,Wenzhong Yan,Jin Zhu,Hualiang Jiang,Wei Wang,Jian Li	2011	10

About Wenzhong Yan

Wenzhong Yan is a scholar working on Physiology, Geriatrics and Gerontology and Molecular Biology, having authored 19 papers that have together received 433 indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (5 papers), Adenosine and Purinergic Signaling (4 papers), Peptidase Inhibition and Analysis (4 papers), Histone Deacetylase Inhibitors Research (4 papers), Pharmacological Receptor Mechanisms and Effects (3 papers), Viral Infections and Immunology Research (3 papers), Signaling Pathways in Disease (3 papers) and Protein Degradation and Inhibitors (2 papers). The work is most often cited by research in Physiology (30 citations), Cellular and Molecular Neuroscience (93 citations) and Molecular Biology (280 citations). Wenzhong Yan has collaborated with scholars based in China, United States and Netherlands. Frequent co-authors include Jianjun Cheng, Liang Tan, John D. McCorvy, Jian Li, Hualiang Jiang, Jin Zhu, Lei Liu, Jinfeng Zhang, Jie Qing and Yaxin Wang.

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