Steven Whitebread

8.0k citations

63 papers · 6.2k indexed · 4 hit papers · h-index 37

Impact in

Endocrine and Autonomic Systems top 0.5%
- Regulation of Appetite and Obesity
Computational Theory and Mathematics top 0.2%
- Computational Drug Discovery Methods

Papers in

Pharmacology 10
- Pharmacogenetics and Drug Metabolism 9
Endocrine and Autonomic Systems 7
- Regulation of Appetite and Obesity 7

Co-authors: Marc de Gasparo Jacques Hamon László Urbán B. Kamber Leoluca Criscione Jeremy L. Jenkins Karl G. Hofbauer Christophe Gerald
Journals: Regulatory Peptides (4 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Journal of Medicinal Chemistry (3 papers)Biochemical and Biophysical Research Communications (3 papers)Diabetes (2 papers)
Partner nations: Switzerland United States United Kingdom

In The Last Decade

Steven Whitebread

62 papers receiving 6.0k citations

Hit Papers

align trajectories log scale

Reducing safety-related drug attrition: the use of in vitro pharmacological profiling 2012 · 485 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2012 Nature Reviews Drug Discovery
2012 Nature
1996 Nature
1989 Biochemical and Biophysical Research Communications

Peers

Countries citing papers authored by Steven Whitebread

Since Specialization

Citations

This map shows the geographic impact of Steven Whitebread's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven Whitebread with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven Whitebread more than expected).

Fields of papers citing papers by Steven Whitebread

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven Whitebread. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven Whitebread. The network helps show where Steven Whitebread may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Steven Whitebread, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Steven Whitebread Line = papers co-authored together Steven Whitebread links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The activities of drug inactive ingredients on biological targets Science ·Joshua Pottel, Duncan Armstrong, Ling Zou, Alexander Fekete, Xi‐Ping Huang, Hayarpi Torosyan, Dallas Bednarczyk, Steven Whitebread, Barun Bhhatarai, Guiqing Liang, Hong Jin, S. Nassir Ghaemi, Samuel T. Slocum, Katalin Lukács, John J. Irwin, Ellen L. Berg, Kathleen M. Giacomini, Bryan L. Roth, Brian K. Shoichet, László Urbán	2020	63
2	Secondary pharmacology: screening and interpretation of off-target activities – focus on translation Drug Discovery Today ·Steven Whitebread, Bérengère Dumotier, Duncan Armstrong, Alexander Fekete, José Zavala Ramírez, Andreas Hartmann, Patrick Muller, László Urbán	2016	45
3	Large-scale prediction and testing of drug activity on side-effect targets Nature ·Eugen Lounkine, Michael J. Keiser, Steven Whitebread, Д. А. Михайлов, Jacques Hamon, Jeremy L. Jenkins, 程亚林, Eckhard Weber, Allison K. Doak, Serge Côté, Brian K. Shoichet, László Urbán Hit paper breakdown →	2012	656
4	Modeling Promiscuity Based on in vitro Safety Pharmacology Profiling Data ChemMedChem ·Khalil Azzaoui, Jacques Hamon, Bernard Faller, Steven Whitebread, Edgar Jacoby, Andreas Bender, Jeremy L. Jenkins, László Urbán	2007	127
5	ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: Identification, in vitro pharmacology, pharmacokinetic and biodistribution studies Bioorganic & Medicinal Chemistry ·Samuel Hintermann, Ivo Vranesic, Hans Allgeier, I. Emmanuel, Daniël Hoyer, Michel Lemaire, A. Ewert, Stephan Urwyler, Steven Whitebread, F. Gasparini, Yves P. Auberson	2006	55
6	Keynote review: In vitro safety pharmacology profiling: an essential tool for successful drug development Drug Discovery Today ·Steven Whitebread, Jacques Hamon, Dejan Bojanic, László Urbán	2005	295
7	Discovery and SAR of potent, orally available and brain-penetrable 5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen- and 4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen derivatives as neuropeptide Y Y5 receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Heinrich Rueeger, Marc Gerspacher, 市川徹, Pascal Rigollier, Yasuchika Yamaguchi, B. N. Udodov, Steven Whitebread, Barbara Nuesslein‐Hildesheim, Hanspeter Nick, Joti Kumari	2004	16
8	Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor. Journal of Clinical Investigation ·Leoluca Criscione, Pascal Rigollier, Christine Batzl‐Hartmann, H. Rüeger, Alain Stricker‐Krongrad, V. A. Mazhar, L. Brunner, Steven Whitebread, Yasuchika Yamaguchi, Christophe Gerald, Rainer O. Heurich, Mary W. Walker, Michele Chiesi, Walter Schilling, Karl G. Hofbauer, N Levens	1998	183
9	Steroidal, Aldosterone Antagonists: Increased selectivity of 9α,11‐epoxy derivatives Helvetica Chimica Acta ·Harinatha Reddy, Qing Liu, Julius Schmidlin, Zuzana Bernátová, P. Wieland, Hermann Führer, Grety Rihs, Urs R. Joss, Marc de Gasparo, Jennifer A. Bartels, I G.P. Sarasutha, Steven Whitebread, J. Kalvoda	1997	17
10	Leptin is a physiologically important regulator of food intake International Journal of Obesity ·L. Brunner, Takramah Kwami Wisdom, Frédéric Cumin, Michele Chiesi, I. E. S. Gómez, Steven Whitebread, Alain Stricker‐Krongrad, N Levens	1997	49
11	A receptor subtype involved in neuropeptide-Y-induced food intake Nature ·Christophe Gerald, Mary W. Walker, Leoluca Criscione, Eric L. Gustafson, Christine Batzl‐Hartmann, Kelli E. Smith, Pierre J.‐J. Vaysse, Margaret M. Durkin, Thomas M. Laz, David L. Linemeyer, Andrea O. Schaffhauser, Steven Whitebread, Karl G. Hofbauer, Robert I. Taber, Theresa A. Branchek, Richard L. Weinshank Hit paper breakdown →	1996	771
12	Localization of Angiotensin II receptor subtypes in the rabbit heart Journal of Molecular and Cellular Cardiology ·Marijke Brink, Pin Hao Ko, H. Rogg, Steven Whitebread, Gillian Bullock	1995	13
13	Binding of valsartan to mammalian angiotensin AT1 receptors Regulatory Peptides ·Marc de Gasparo, Steven Whitebread	1995	102
14	Renal actions of the angiotensin AT2 receptor ligands CGP 42112 and PD 123319 after blockade of the renin-angiotensin system European Journal of Pharmacology ·Mutia Larasati, Steven Whitebread, Frédéric Cumin, Marc de Gasparo, N Levens	1994	51
15	Renal actions of the selective angiotensin AT2 receptor ligands CGP 42112B and PD 123319 in the sodium-depleted rat European Journal of Pharmacology ·Mutia Larasati, Serge P. Bottari, Steven Whitebread, Marc de Gasparo, Nigel Levens	1993	72
16	Nonpeptidic angiotensin II antagonists: synthesis and in vitro activity of a series of novel naphthalene and tetrahydronaphthalene derivatives Journal of Medicinal Chemistry ·Peter Bühlmayer, Leoluca Criscione, Walter Fuhrer, Pascal Furet, Marc de Gasparo, Stefan Stutz, Steven Whitebread	1991	29
17	Angiotensin II AT2 receptors do not interact with guanine nucleotide binding proteins European Journal of Pharmacology Molecular Pharmacology ·Serge P. Bottari, Verdon Taylor, Isabelle N. King, Gloria Bellido Zanin, Steven Whitebread, Marc de Gasparo	1991	111
18	Potentiation of angiotensin II‐stimulated phosphoinositide hydrolysis, calcium mobilization and contraction of renal mesangial cells upon down‐regulation of protein kinase C FEBS Letters ·Josef Pfeilschifter, Joachim Fandrey, Martin Ochsner, Steven Whitebread, Marc de Gasparo	1990	31
19	Biochemical Characterization of Two Angiotensin II Receptor Subtypes in the Rat Journal of Cardiovascular Pharmacology ·Marc de Gasparo, Steven Whitebread, A. Chang, Alykhan Motani, P Mower Jeffrey, Walter Ludwig Armin Schroff, B. Kamber	1990	84
20	Preliminary biochemical characterization of two angiotensin II receptor subtypes Biochemical and Biophysical Research Communications ·Steven Whitebread, A. Chang, B. Kamber, Marc de Gasparo Hit paper breakdown →	1989	668

About Steven Whitebread

Steven Whitebread is a scholar working on Pharmacology, Endocrine and Autonomic Systems, Cardiology and Cardiovascular Medicine, Computational Theory and Mathematics and Cellular and Molecular Neuroscience, having authored 63 papers that have together received 6.2k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (27 papers), Renin-Angiotensin System Studies (15 papers), Computational Drug Discovery Methods (13 papers), Neuropeptides and Animal Physiology (10 papers), Pharmacogenetics and Drug Metabolism (9 papers), Hormonal Regulation and Hypertension (7 papers), Regulation of Appetite and Obesity (7 papers) and Neuroendocrine regulation and behavior (5 papers). The work is most often cited by research in Endocrine and Autonomic Systems (932 citations), Computational Theory and Mathematics (1.6k citations), Cellular and Molecular Neuroscience (1.4k citations), Cardiology and Cardiovascular Medicine (1.6k citations) and Pharmacology (569 citations). Steven Whitebread has collaborated with scholars based in Switzerland, United States and United Kingdom. Frequent co-authors include Marc de Gasparo, Jacques Hamon, László Urbán, B. Kamber, Leoluca Criscione, Jeremy L. Jenkins, Karl G. Hofbauer, Christophe Gerald, Andrea O. Schaffhauser and Dejan Bojanic. Their work appears in journals such as Regulatory Peptides, Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Biochemical and Biophysical Research Communications and Diabetes.

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