Philippe Giguère

4.3k total citations · 2 hit papers
42 papers, 2.8k citations indexed

About

Philippe Giguère is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Infectious Diseases. According to data from OpenAlex, Philippe Giguère has authored 42 papers receiving a total of 2.8k indexed citations (citations by other indexed papers that have themselves been cited), including 30 papers in Molecular Biology, 17 papers in Cellular and Molecular Neuroscience and 5 papers in Infectious Diseases. Recurrent topics in Philippe Giguère's work include Receptor Mechanisms and Signaling (21 papers), Neuropeptides and Animal Physiology (13 papers) and Protein Kinase Regulation and GTPase Signaling (8 papers). Philippe Giguère is often cited by papers focused on Receptor Mechanisms and Signaling (21 papers), Neuropeptides and Animal Physiology (13 papers) and Protein Kinase Regulation and GTPase Signaling (8 papers). Philippe Giguère collaborates with scholars based in United States, Canada and Australia. Philippe Giguère's co-authors include Bryan L. Roth, Xi‐Ping Huang, John D. McCorvy, Maria F. Sassano, David P. Siderovski, Wesley K. Kroeze, Noah Sciaky, Katherine Lansu, Adam J. Kimple and Raymond C. Stevens and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

Philippe Giguère

42 papers receiving 2.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structure-based discovery of opioid analgesics with reduced side effects

2016 697 citations John D. McCorvy, Xi‐Ping Huang et al. Nature profile →
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

2015 519 citations Wesley K. Kroeze, Maria F. Sassano et al. Nature Structural & Molecular Biology profile →

Peers

Philippe Giguère

CMN

IMMUN

PHYSI

CTM

Mohammed Akli Ayoub United Arab Emirates

Berta Strulovici United States

Hideaki Kato Japan

Susana R. Neves United States

Thomas Weiser Germany

Holger Husi United Kingdom

Aylin C. Hanyaloglu United Kingdom

André Schrattenholz Germany

Shoji Maeda Japan

Jonathan Bard United States

Mohammed Akli Ayoub United Arab Emirates

Philippe Giguère

2.9k ×1.4

1.5k ×1.2

CMN

259 ×0.9

IMMUN

305 ×1.3

PHYSI

125 ×0.6

CTM

Citations per year, relative to Philippe Giguère Philippe Giguère (= 1×) peers Mohammed Akli Ayoub

Countries citing papers authored by Philippe Giguère

Since Specialization

Citations

This map shows the geographic impact of Philippe Giguère's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philippe Giguère with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philippe Giguère more than expected).

Fields of papers citing papers by Philippe Giguère

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philippe Giguère. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philippe Giguère. The network helps show where Philippe Giguère may publish in the future.

Co-authorship network of co-authors of Philippe Giguère

This figure shows the co-authorship network connecting the top 25 collaborators of Philippe Giguère. A scholar is included among the top collaborators of Philippe Giguère based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Philippe Giguère. Philippe Giguère is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Laroche, Geneviève, et al.. (2023). Profiling of basal and ligand-dependent GPCR activities by means of a polyvalent cell-based high-throughput platform. Nature Communications. 14(1). 3684–3684. 8 indexed citations

Laroche, Geneviève, et al.. (2023). Development of a V5-tag–directed nanobody and its implementation as an intracellular biosensor of GPCR signaling. Journal of Biological Chemistry. 299(9). 105107–105107. 16 indexed citations

Giguère, Philippe, et al.. (2022). Distinct functional roles for the M4 α-helix from each homologous subunit in the heteropentameric ligand-gated ion channel nAChR. Journal of Biological Chemistry. 298(7). 102104–102104. 3 indexed citations

Bo, Yuxia, Nicholas D. LeBlond, Geneviève Laroche, et al.. (2021). Ebola virus triggers receptor tyrosine kinase-dependent signaling to promote the delivery of viral particles to entry-conducive intracellular compartments. PLoS Pathogens. 17(1). e1009275–e1009275. 15 indexed citations

Laroche, Geneviève & Philippe Giguère. (2019). Measurement of β-Arrestin Recruitment at GPCRs Using the Tango Assay. Methods in molecular biology. 1947. 257–267. 6 indexed citations

Gendron, Louis, et al.. (2019). Molecular aspects of delta opioid receptors. Vitamins and hormones. 111. 49–90. 7 indexed citations

Cheng, Jianjun, Philippe Giguère, Wei Lv, Bryan L. Roth, & Alan P. Kozikowski. (2015). Design and synthesis of (2-(5-chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)cyclopropyl)methanamine as a selective serotonin 2C agonist. Tetrahedron Letters. 56(23). 3420–3422. 14 indexed citations

Kroeze, Wesley K., Maria F. Sassano, Xi‐Ping Huang, et al.. (2015). PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome. Nature Structural & Molecular Biology. 22(5). 362–369. 519 indexed citations breakdown →

Giguère, Philippe, Geneviève Laroche, Brian K. Buckley, et al.. (2014). G Protein Signaling Modulator-3 Inhibits the Inflammasome Activity of NLRP3. Journal of Biological Chemistry. 289(48). 33245–33257. 25 indexed citations

10.

Fenalti, Gustavo, Philippe Giguère, Vsevolod Katritch, et al.. (2014). Molecular control of δ-opioid receptor signalling. Nature. 506(7487). 191–196. 396 indexed citations

11.

Lee, Hyeong-Min, Philippe Giguère, & Bryan L. Roth. (2013). DREADDs: novel tools for drug discovery and development. Drug Discovery Today. 19(4). 469–473. 74 indexed citations

12.

Giguère, Philippe, Wesley K. Kroeze, & Bryan L. Roth. (2013). Tuning up the right signal: chemical and genetic approaches to study GPCR functions. Current Opinion in Cell Biology. 27. 51–55. 19 indexed citations

13.

Giguère, Philippe, Geneviève Laroche, Emily A. Oestreich, Joseph A. Duncan, & David P. Siderovski. (2012). Regulation of the Subcellular Localization of the G-protein Subunit Regulator GPSM3 through Direct Association with 14-3-3 Protein. Journal of Biological Chemistry. 287(37). 31270–31279. 7 indexed citations

14.

Bosch, Dustin E., Adam J. Kimple, Philippe Giguère, et al.. (2012). Heterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica. PLoS Pathogens. 8(11). e1003040–e1003040. 21 indexed citations

15.

Giguère, Philippe, Geneviève Laroche, Emily A. Oestreich, & David P. Siderovski. (2011). G-protein Signaling Modulator-3 Regulates Heterotrimeric G-protein Dynamics through Dual Association with Gβ and Gαi Protein Subunits. Journal of Biological Chemistry. 287(7). 4863–4874. 14 indexed citations

16.

Kimple, Adam J., Francis S. Willard, Philippe Giguère, et al.. (2007). The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Gα-interaction face. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1774(9). 1213–1220. 46 indexed citations

17.

Laroche, Geneviève, et al.. (2007). The N-terminal coiled-coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with Gαq. Molecular and Cellular Biochemistry. 306(1-2). 141–152. 12 indexed citations

18.

Giguère, Philippe, Audrey V. Parent, Geneviève Laroche, et al.. (2007). Peroxiredoxin‐4 interacts with and regulates the thromboxane A₂ receptor. FEBS Letters. 581(20). 3863–3868. 37 indexed citations

19.

Giguère, Philippe, Moulay Driss Rochdi, Geneviève Laroche, et al.. (2006). ARF6 activation by Gαq signaling: Gαq forms molecular complexes with ARNO and ARF6. Cellular Signalling. 18(11). 1988–1994. 25 indexed citations

20.

Ear, Thornin, Philippe Giguère, Alain Fleury, et al.. (2001). High efficiency transient transfection of genes in human umbilical vein endothelial cells by electroporation. Journal of Immunological Methods. 257(1-2). 41–49. 26 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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