Sidney M. Hecht

23.1k citations

457 papers · 19.2k indexed · 1 hit paper · h-index 63

Impact in

Toxicology top 0.02%
- Bioactive Compounds and Antitumor Agents
Molecular Biology top 0.1%
- Cancer therapeutics and mechanisms
- DNA and Nucleic Acid Chemistry
- RNA and protein synthesis mechanisms
- Advanced biosensing and bioanalysis techniques
- Chemical Synthesis and Analysis
- RNA modifications and cancer

Papers in

Toxicology 39
- Bioactive Compounds and Antitumor Agents 39
Molecular Biology 369
- DNA and Nucleic Acid Chemistry 117
- RNA and protein synthesis mechanisms 110
- Cancer therapeutics and mechanisms 84
- RNA modifications and cancer 61
- Chemical Synthesis and Analysis 51

Co-authors: Robert Hertzberg Y H Hsiang Leroy F. Liu Mary Jo Caranfa Luis O. Rodriguez Larisa M. Dedkova Nicolas J. Rahier Shengxi Chen
Journals: Journal of the American Chemical Society (89 papers)Biochemistry (70 papers)Bioorganic & Medicinal Chemistry (42 papers)Journal of Biological Chemistry (33 papers)Journal of Natural Products (31 papers)
Partner nations: United States Netherlands France

In The Last Decade

Sidney M. Hecht

456 papers receiving 18.6k citations

Hit Papers

align trajectories log scale

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. 1985 · 2.0k citations

Peers

Countries citing papers authored by Sidney M. Hecht

Since Specialization

Citations

This map shows the geographic impact of Sidney M. Hecht's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sidney M. Hecht with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sidney M. Hecht more than expected).

Fields of papers citing papers by Sidney M. Hecht

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sidney M. Hecht. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sidney M. Hecht. The network helps show where Sidney M. Hecht may publish in the future.

Co-authors

The 25 scholars most cited alongside Sidney M. Hecht, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Sidney M. Hecht Line = papers co-authored together Sidney M. Hecht links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Alteration of CD40 Protein Expression by Tyrosine Phosphorylation of the NF‐ κ B p50 Subunit ChemBioChem ·Shengxi Chen, Gongli Li, Xun Ji, Sidney M. Hecht	2025	0
2	Expedited quantification of mutant ribosomal RNA by binary deoxyribozyme (BiDz) sensors RNA ·Yulia V. Gerasimova, Petro Yakovchuk, Larisa M. Dedkova, Sidney M. Hecht, Dmitry M. Kolpashchikov	2015	14
3	The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure Journal of the American Chemical Society ·Samantha Kendrick, Hyun-Jin Kang, Mohammad P. Alam, Manikandadas M. Madathil, Prashansa Agrawal, Vijay Gokhale, Danzhou Yang, Sidney M. Hecht, Laurence H. Hurley	2014	237
4	Probing of CD4 binding pocket of HIV-1 gp120 glycoprotein using unnatural phenylalanine analogues Bioorganic & Medicinal Chemistry Letters ·Xiaobo Yu, Наталья Гефан, Chandrabali Bhattacharya, Nour Eddine Fahmi, B Vidhya, Larisa M. Dedkova, Joshua LaBaer, Sidney M. Hecht, Shengxi Chen	2014	6
5	Selective Tumor Cell Targeting by the Disaccharide Moiety of Bleomycin Journal of the American Chemical Society ·Zhiqiang Yu, Simona Filiposka, L. A. Maffia, R. J. Paul, Michael J. Rishel, Krystal S. Tsosie, Sidney M. Hecht	2013	237
6	Incorporation of β-amino acids into dihydrofolate reductase by ribosomes having modifications in the peptidyltransferase center Bioorganic & Medicinal Chemistry ·Rumit Maini, Dan T. Nguyen, Shengxi Chen, Larisa M. Dedkova, Sandipan Chowdhury, M. Ángeles López Garrido, Sidney M. Hecht	2013	65
7	Synthesis and Biological Activities of Topopyrones Journal of Natural Products ·M. Gaussin, Rumit Maini, 王德营, Ann John Mampilli, Sidney M. Hecht	2012	13
8	Modeling the reactive properties of tandemly activated tRNAs Organic & Biomolecular Chemistry ·Maria Duca, Shengxi Chen, Sidney M. Hecht	2008	8
9	Identification of the First Specific Inhibitor of p90 Ribosomal S6 Kinase (RSK) Reveals an Unexpected Role for RSK in Cancer Cell Proliferation Cancer Research ·Jeffrey A. Smith, Celeste E. Poteet-Smith, Ya-Ming Xu, Timothy M. Errington, Sidney M. Hecht, Deborah A. Lannigan	2005	246
10	New lupane triterpenoids from Solidago canadensis that inhibit the lyase activity of DNA polymerase β Bioorganic & Medicinal Chemistry ·Venkata Sai Prakash Chaturvedula, KMB Adjukeiwicz, Zhijie Gao, Laura Shaikhislamovna Seitzhanova, Sidney M. Hecht, David G. I. Kingston	2004	40
11	On the role of E-ring oxygen atoms in the binding of camptothecin to the topoisomerase I–DNA covalent binary complex Bioorganic & Medicinal Chemistry ·Nicolas J. Rahier, Brian M. Eisenhauer, Rong Gao, Laura Shaikhislamovna Seitzhanova, Sidney M. Hecht	2004	14
12	Plant sterols as selective DNA polymerase β lyase inhibitors and potentiators of bleomycin cytotoxicity Bioorganic & Medicinal Chemistry ·Martha Alexandra Macias Cedeño, Zhijie Gao, Xizhi Feng, Shannon H. Jones, Sidney M. Hecht	2004	16
13	Guarding the Genome Molecular Cell ·D.L. Ormond, Renaly Gonçalves, Sidney M. Hecht, Stewart Shuman	2003	31
14	Facile characterization of translation initiation via nonsense codon suppression Nucleic Acids Research ·Andrei V. Karginov, Michiel Lodder, Sidney M. Hecht	1999	6
15	Bioorganic chemistry : peptides and proteins Oxford University Press eBooks ·Sidney M. Hecht	1998	76
16	Structurally Altered Substrates for DNA Topoisomerase. I. Effects of Inclusion of a Single 3'-Deoxynucleotide Within the Scissile Strand Nucleosides Nucleotides & Nucleic Acids ·Yann Paclot, Anil Abraham, Sidney M. Hecht	1998	6
17	In Vitro Suppression as a Tool for the Investigation of Translation Initiation Nucleic Acids Research ·Vladimir A. Karginov, Sergey Mamaev, Sidney M. Hecht	1997	11
18	Bioorganic chemistry : nucleic acids Oxford University Press eBooks ·Sidney M. Hecht	1996	139
19	Copper(II) facilitates bleomycin-mediated unwinding of plasmid DNA Biochemistry ·Emrizal Emrizal, Sidney M. Hecht	1988	29
20	2′-OH vs 3′-OH Specificity in tRNA Aminoacylation Cold Spring Harbor Monograph Archive ·Sidney M. Hecht	1979	8

About Sidney M. Hecht

Sidney M. Hecht is a scholar working on Toxicology, Molecular Biology, Organic Chemistry, Oncology and Biochemistry, having authored 457 papers that have together received 19.2k indexed citations. Recurring topics across this work include DNA and Nucleic Acid Chemistry (117 papers), RNA and protein synthesis mechanisms (110 papers), Cancer therapeutics and mechanisms (84 papers), RNA modifications and cancer (61 papers), Chemical Synthesis and Analysis (51 papers), Metal complexes synthesis and properties (47 papers), Synthesis and Biological Evaluation (42 papers) and Bioactive Compounds and Antitumor Agents (39 papers). The work is most often cited by research in Toxicology (1.6k citations), Molecular Biology (14.6k citations), Organic Chemistry (5.2k citations), Oncology (4.0k citations) and Pharmacology (1.4k citations). Sidney M. Hecht has collaborated with scholars based in United States, Netherlands and France. Frequent co-authors include Robert Hertzberg, Y H Hsiang, Leroy F. Liu, Mary Jo Caranfa, Luis O. Rodriguez, Larisa M. Dedkova, Nicolas J. Rahier, Shengxi Chen, Craig J. Thomas and Laurence H. Hurley. Their work appears in journals such as Journal of the American Chemical Society, Biochemistry, Bioorganic & Medicinal Chemistry, Journal of Biological Chemistry and Journal of Natural Products.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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