Ursula A. Germann

6.4k citations

49 papers · 4.8k indexed · 1 hit paper · h-index 31

Impact in

Oncology top 0.5%
- Drug Transport and Resistance Mechanisms
Pediatrics, Perinatology and Child Health top 1%
- Pharmacological Effects and Toxicity Studies

Papers in

Physiology 6
- Adenosine and Purinergic Signaling 6
Oncology 27
- Drug Transport and Resistance Mechanisms 26

Co-authors: Michael M. Gottesman Ira Pastan Balázs Sarkadi Elmer M. Price Christine A. Hrycyna R. C. Boucher Konrad Lerch Gene A. Scarborough
Journals: Journal of Biological Chemistry (8 papers)Biochemistry (4 papers)Anti-Cancer Drugs (2 papers)The FASEB Journal (2 papers)Proceedings of the National Academy of Sciences (2 papers)
Partner nations: United States Switzerland Hungary

In The Last Decade

Ursula A. Germann

49 papers receiving 4.7k citations

Hit Papers

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Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase. 1992 · 562 citations

Peers

Countries citing papers authored by Ursula A. Germann

Since Specialization

Citations

This map shows the geographic impact of Ursula A. Germann's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ursula A. Germann with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ursula A. Germann more than expected).

Fields of papers citing papers by Ursula A. Germann

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ursula A. Germann. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ursula A. Germann. The network helps show where Ursula A. Germann may publish in the future.

Co-authors

The 25 scholars most cited alongside Ursula A. Germann, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ursula A. Germann Line = papers co-authored together Ursula A. Germann links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	(S)-1-((S)-2-{[1-(4-Amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2 R,3 S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an Orally Available Selective Interleukin (IL)-Converting Enzyme/Caspase-1 Inhibitor, Exhibits Potent Anti-Inflammatory Activities by Inhibiting the Release of IL-1β and IL-18 Journal of Pharmacology and Experimental Therapeutics ·Qiuyan Zeng, A. Milogorodskii, Mark Namchuk, John R. Pollard, Pamella J. Ford, George Ku, Caroline J. Decker, Paul S. Charifson, Peter Weber, Ursula A. Germann, Keisuke Kuida, John C.R. Randle	2007	250
2	c-Jun N-Terminal Kinases Mediate Reactivation of Akt and Cardiomyocyte Survival After Hypoxic Injury In Vitro and In Vivo Circulation Research ·Zhili Shao, Kausik Bhattacharya, Eileen Hsich, Larry Park, Brian Walters, Ursula A. Germann, Yow‐Ming Wang, John Kyriakis, Ramon Mohanlal, Keisuke Kuida, Mark Namchuk, Francesco G. Salituro, Yung‐Mae Yao, Weimin Hou, Xin Chen, Mark Aronovitz, Philip N. Tsichlis, Susmita Bhattacharya, Thomas Force, Heiko Kilter	2005	106
3	Detection of Expressed Recombinant Protein Based on Multidrug Resistance: P-Glycoprotein Humana Press eBooks ·Ursula A. Germann	2003	1
4	Detection of Recombinant P-Glycoprotein in Multidrug Resistant Cultured Cells Molecular Biotechnology ·Ursula A. Germann	2000	6
5	Inhibitors ofp38 MAP Kinase: TherapeuticIntervention inCytokine-Mediated Diseases Current Medicinal Chemistry ·Francesco G. Salituro, Ursula A. Germann, Keith P. Wilson, Guy W. Bemis, Ted Fox, Michael Su	1999	71
6	[31] Baculovirus-mediated expression of human multidrug resistance cDNA in insect cells and functional analysis of recombinant P-glycoprotein Methods in enzymology on CD-ROM/Methods in enzymology ·Ursula A. Germann	1998	14
7	Cellular and biochemical characterization of VX-710 as a chemosensitizer Anti-Cancer Drugs ·Ursula A. Germann, Stuttgart Satz, Valerie S. Mason, Robert E. Zelle, John P. Duffy, Vincent Galullo, David M. Armistead, Jeffrey O. Saunders, Joshua Boger, Matthew W. Harding	1997	119
8	Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP Anti-Cancer Drugs ·Ursula A. Germann, Pamella J. Ford, Leo Katzen, Valerie S. Mason, Matthew W. Harding	1997	113
9	Characterization of Phosphorylation-defective Mutants of Human P-glycoprotein Expressed in Mammalian Cells Journal of Biological Chemistry ·Ursula A. Germann, Timothy C. Chambers, Suresh V. Ambudkar, Thomas Licht, Carol Cardarelli, Ira Pastan, Michael M. Gottesman	1996	149
10	P-glycoprotein—A mediator of multidrug resistance in tumour cells European Journal of Cancer ·Ursula A. Germann	1996	368
11	Effects of phosphorylation of P-glycoprotein on multidrug resistance Journal of Bioenergetics and Biomembranes ·Ursula A. Germann, Timothy C. Chambers, Suresh V. Ambudkar, Ira Pastan, Michael M. Gottesman	1995	57
12	Bacterial expression of the linker region of human MDR1 P-glycoprotein and mutational analysis of phosphorylation sites Biochemistry ·Timothy C. Chambers, Ursula A. Germann, Michael M. Gottesman, Ira Pastan, J.F. Kuo, Suresh V. Ambudkar	1995	16
13	GENETIC ANALYSIS OF THE MULTIDRUG TRANSPORTER Annual Review of Genetics ·Michael M. Gottesman, Christine A. Hrycyna, Patricia V. Schoenlein, Ursula A. Germann, Ira Pastan	1995	417
14	Heterologous expression systems for P-glycoprotein:E. coli, yeast, and baculovirus Journal of Bioenergetics and Biomembranes ·Wendi Abraham, Baofu Ni, Christine A. Hrycyna, David D. Y. Chen, Suresh V. Ambudkar, I Pastan, Ursula A. Germann, Michael M. Gottesman	1995	41
15	Putative “MDR enhancer” is located on human chromosome 20 and not linked to the MDRI gene on chromosome 7 Genes Chromosomes and Cancer ·Ursula A. Germann, Patricia V. Schoenlein, Drazen B. Zimonjic, Nicholas C. Popescu, Ira Pastan, Michael M. Gottesman	1994	6
16	Gene Transfer of Drug Resistance Genes Implications for Cancer Therapy Annals of the New York Academy of Sciences ·Michael M. Gottesman, Ursula A. Germann, I Aksentijevich, Yoshikazu Sugimoto, Carol Cardarelli, Ira Pastan	1994	27
17	Regulation of laccase synthesis in induced Neurospora crassa cultures Current Genetics ·R. Michael Linden, Boris Schilling, Ursula A. Germann, Konrad Lerch	1991	17
18	Characterization by somatic cell genetics of a monoclonal antibody to the MDR1 gene product (P‐glycoprotein): Determination of p‐glycoprotein expression in multi‐drug‐resistant kb and cem cell variants International Journal of Cancer ·Cristina Cenciarelli, Stephen J. Currier, Mark C. Willingham, SunJiangwen, Ursula A. Germann, A V Rutherford, Michael M. Gottesman, Stefano Barca, J. L. Doremieux, Stefania Morrone, Angela Santoni, Massimo A. Mariani, Carlo Ramoni, Maria Luisa Dupuis, Maurizio Cianfriglia	1991	32
19	Expression of the human multidrug transporter in insect cells by a recombinant baculovirus Biochemistry ·Ursula A. Germann, Mark C. Willingham, Ira Pastan, Michael M. Gottesman	1990	110
20	Isolation and Regulation of Expression of the Neurospora Crassa Copper Metallothionein Gene Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions ·Karl Münger, Ursula A. Germann, Konrad Lerch	1987	11

About Ursula A. Germann

Ursula A. Germann is a scholar working on Physiology, Oncology, Biochemistry, Infectious Diseases and Molecular Biology, having authored 49 papers that have together received 4.8k indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (26 papers), HIV/AIDS drug development and treatment (10 papers), Melanoma and MAPK Pathways (6 papers), Adenosine and Purinergic Signaling (6 papers), Amino Acid Enzymes and Metabolism (5 papers), Enzyme-mediated dye degradation (4 papers), RNA Interference and Gene Delivery (4 papers) and Biochemical and Molecular Research (4 papers). The work is most often cited by research in Oncology (2.9k citations), Pediatrics, Perinatology and Child Health (935 citations), Infectious Diseases (791 citations), Physiology (176 citations) and Molecular Biology (2.4k citations). Ursula A. Germann has collaborated with scholars based in United States, Switzerland and Hungary. Frequent co-authors include Michael M. Gottesman, Ira Pastan, Balázs Sarkadi, Elmer M. Price, Christine A. Hrycyna, R. C. Boucher, Konrad Lerch, Gene A. Scarborough, I Pastan and Patricia V. Schoenlein. Their work appears in journals such as Journal of Biological Chemistry, Biochemistry, Anti-Cancer Drugs, The FASEB Journal and Proceedings of the National Academy of Sciences.

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