George Ku

5.0k citations

30 papers · 4.2k indexed · 2 hit papers · h-index 21

Impact in

Immunology top 1%
- Immune Response and Inflammation
- Immune Cell Function and Interaction
- interferon and immune responses
- IL-33, ST2, and ILC Pathways
- Atherosclerosis and Cardiovascular Diseases
Biochemistry top 2%
- Antioxidant Activity and Oxidative Stress

Papers in

Biochemistry 5
- Antioxidant Activity and Oxidative Stress 5
Immunology 14
- Immune Response and Inflammation 5
- Atherosclerosis and Cardiovascular Diseases 4
- Immune Cell Function and Interaction 3

Co-authors: Matthew W. Harding Keisuke Kuida David J. Livingston Richard A. Flavell Michael Su Judith A. Lippke Richard L. Jackson Craig E. Thomas
Journals: The Journal of Immunology (5 papers)Science (3 papers)Journal of Lipid Research (2 papers)Blood (2 papers)Expert Opinion on Investigational Drugs (1 paper)
Partner nations: United States Japan Portugal

In The Last Decade

George Ku

30 papers receiving 4.1k citations

Hit Papers

align trajectories log scale

Activation of Interferon-γ Inducing Factor Mediated by Interleukin-1β Converting Enzyme 1997 · 996 citations

Peers

Countries citing papers authored by George Ku

Since Specialization

Citations

This map shows the geographic impact of George Ku's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by George Ku with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites George Ku more than expected).

Fields of papers citing papers by George Ku

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by George Ku. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by George Ku. The network helps show where George Ku may publish in the future.

Co-authorship network

The 25 scholars most cited alongside George Ku, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with George Ku Line = papers co-authored together George Ku links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X₇ receptor‐mediated IL‐1β release Journal of Neurochemistry ·Liliana Bernardino, Silvia Balosso, Teresa Ravizza, Nicola Marchi, George Ku, John C.R. Randle, João O. Malva, Annamaria Vezzani	2008	66
2	(S)-1-((S)-2-{[1-(4-Amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2 R,3 S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an Orally Available Selective Interleukin (IL)-Converting Enzyme/Caspase-1 Inhibitor, Exhibits Potent Anti-Inflammatory Activities by Inhibiting the Release of IL-1β and IL-18 Journal of Pharmacology and Experimental Therapeutics ·Qiuyan Zeng, A. Milogorodskii, Mark Namchuk, John R. Pollard, Pamella J. Ford, George Ku, Caroline J. Decker, Paul S. Charifson, Peter Weber, Ursula A. Germann, Keisuke Kuida, John C.R. Randle	2007	250
3	Inactivation of Caspase‐1 in Rodent Brain: A Novel Anticonvulsive Strategy Epilepsia ·Teresa Ravizza, С М Куликова, Silvia Balosso, Liliana Bernardino, George Ku, Francesco M. Noè, João O. Malva, John C.R. Randle, Stuart M. Allan, Annamaria Vezzani	2006	141
4	IL-18 translational inhibition restricts IFN-γ expression in crescentic glomerulonephritis Kidney International ·Gabriela García, Yiyang Xia, George Ku, Richard J. Johnson, Curtis B. Wilson, Lili Feng	2003	15
5	Coadministration of interleukin-18 and interleukin-12 induces a fatal inflammatory response in mice: critical role of natural killer cell interferon-γ production and STAT-mediated signal transduction Blood ·William E. Carson, Julie Dierksheide, Helmy Ramadhan Al Anshary, Mirela Anghelina, Page Bouchard, George Ku, Haixin Yu, Heinz Baumann, Manisha H. Shah, Megan A. Cooper, Joan E. Durbin, Michael A. Caligiuri	2000	89
6	A Fatal Cytokine-Induced Systemic Inflammatory Response Reveals a Critical Role for NK Cells The Journal of Immunology ·William E. Carson, Haixin Yu, Julie Dierksheide, Klaus Pfeffer, Page Bouchard, А Д Китов, Joan E. Durbin, Albert S. Baldwin, Jacques J. Peschon, Philip R. Johnson, George Ku, Heinz Baumann, Michael A. Caligiuri	1999	91
7	Severity and Mortality of Experimental Pancreatitis Are Dependent on Interleukin-1 Converting Enzyme (ICE) Journal of Interferon & Cytokine Research ·Jim C. Norman, Jun Yang, G Fink, C. S. Franscisco, George Ku, Woody Denham, David P. Livingston	1997	71
8	Response to local inflammation of IL-1 beta-converting enzyme- deficient mice The Journal of Immunology ·Giamila Fantuzzi, George Ku, Matthew W. Harding, David J. Livingston, Jean D. Sipe, Keisuke Kuida, R. A. Flavell, C A Dinarello	1997	192
9	INTERLEUKIN-1β CONVERTING ENZYME INHIBITION BLOCKS PROGRESSION OF TYPE II COLLAGEN-INDUCED ARTHRITIS IN MICE Cytokine ·George Ku, أسماء السيد السيد شعبان شعبان, Jospeh Y. Drabo, David J. Livingston, Matthew W. Harding	1996	90
10	Altered Cytokine Export and Apoptosis in Mice Deficient in Interleukin-1β Converting Enzyme Science ·Keisuke Kuida, Judith A. Lippke, George Ku, Matthew W. Harding, David J. Livingston, Michael Su, Richard A. Flavell Hit paper breakdown →	1995	1405
11	Multiple lipid oxidation products in low density lipoproteins induce interleukin-1 beta release from human blood mononuclear cells. Journal of Lipid Research ·Craig E. Thomas, Richard L. Jackson, David F. Ohlweiler, George Ku	1994	107
12	Nitrone spin trap lipophilicity as a determinant for inhibition of low density lipoprotein oxidation and activation of interleukin-1 beta release from human monocytes. Journal of Lipid Research ·Craig E. Thomas, George Ku, B. Kalyanaraman	1994	17
13	Antioxidants: A biological defense mechanism for the prevention of atherosclerosis Medicinal Research Reviews ·Richard L. Jackson, George Ku, Craig E. Thomas	1993	41
14	Synthesis and biological activity of sulfoximine-modified myristic acid analogues Bioorganic & Medicinal Chemistry Letters ·Ian A. McDonald, Marshburn, George Ku, Terry L. Bowlin	1993	2
15	A protective role for nitric oxide in the oxidative modification of low density lipoproteins by mouse macrophages FEBS Letters ·Mark T. Yates, Laurie E. Lambert, Jeffrey P. Whitten, Ian A. McDonald, Masayuki Mano, George Ku, Simon J.T. Mao	1992	92
16	Probucol does not alter acetylated low density lipoprotein uptake by murine peritoneal macrophages Atherosclerosis ·George Ku, 恭子中野, Lisa Schmidt, Richard L. Jackson, Niall S. Doherty	1990	8
17	Ex vivo lipopolysaccharide‐induced interleukiri‐1 secretion from murine peritoneal macrophages inhibited by probucol, a hypocholesterolemic agent with antioxidant properties The FASEB Journal ·George Ku, Niall S. Doherty, Lisa Schmidt, Richard L. Jackson, Robert J. Dinerstein	1990	67
18	Inhibition by probucol of interleukin 1 secretion and its implication in atherosclerosis The American Journal of Cardiology ·George Ku, Niall S. Doherty, Jeffrey A. Wolos, Richard L. Jackson, Lisa Schmidt, Elisa P Carbonell	1988	81
19	Corticosteroid-resistant bone marrow-derived B lymphocyte progenitor for long term in vitro cultures. The Journal of Immunology ·George Ku, Owen N. Witte	1986	14
20	The inhibition of the mitogenic stimulation of B lymphocytes by a serine protease inhibitor: commitment to proliferation correlates with an enhanced expression of a cell-associated arginine-specific serine enzyme. The Journal of Immunology ·George Ku, J. P. Quigley, Barnet M. Sultzer	1983	40

About George Ku

George Ku is a scholar working on Biochemistry, Immunology, Immunology and Allergy, Cancer Research and Physiology, having authored 30 papers that have together received 4.2k indexed citations. Recurring topics across this work include Inflammasome and immune disorders (6 papers), Immune Response and Inflammation (5 papers), Antioxidant Activity and Oxidative Stress (5 papers), Atherosclerosis and Cardiovascular Diseases (4 papers), Cytokine Signaling Pathways and Interactions (4 papers), Immune Cell Function and Interaction (3 papers), Cholesterol and Lipid Metabolism (3 papers) and NF-κB Signaling Pathways (3 papers). The work is most often cited by research in Immunology (2.0k citations), Biochemistry (213 citations), Molecular Biology (2.4k citations), Hematology (254 citations) and Physiology (98 citations). George Ku has collaborated with scholars based in United States, Japan and Portugal. Frequent co-authors include Matthew W. Harding, Keisuke Kuida, David J. Livingston, Richard A. Flavell, Michael Su, Judith A. Lippke, Richard L. Jackson, Craig E. Thomas, Kazuya Higashino and Mark Fleming. Their work appears in journals such as The Journal of Immunology, Science, Journal of Lipid Research, Blood and Expert Opinion on Investigational Drugs.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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