R. Michael Linden

4.9k total citations · 2 hit papers
51 papers, 3.7k citations indexed

About

R. Michael Linden is a scholar working on Genetics, Molecular Biology and Epidemiology. According to data from OpenAlex, R. Michael Linden has authored 51 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 44 papers in Genetics, 32 papers in Molecular Biology and 10 papers in Epidemiology. Recurrent topics in R. Michael Linden's work include Virus-based gene therapy research (43 papers), CRISPR and Genetic Engineering (16 papers) and RNA Interference and Gene Delivery (12 papers). R. Michael Linden is often cited by papers focused on Virus-based gene therapy research (43 papers), CRISPR and Genetic Engineering (16 papers) and RNA Interference and Gene Delivery (12 papers). R. Michael Linden collaborates with scholars based in United States, United Kingdom and France. R. Michael Linden's co-authors include Kenneth I. Berns, Ernest Winocour, Peter Ward, Els Henckaerts, Robert M. Kotin, Catherine Giraud, Marion Kennedy, Gordon Keller, Steven Kattman and Torsten K. Roepke and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

R. Michael Linden

50 papers receiving 3.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

2008 1.1k citations Lei Yang, Mark H. Soonpaa et al. Nature profile →
Site-specific integration by adeno-associated virus.

1996 614 citations R. Michael Linden, Kenneth I. Berns et al. profile →

Peers

Countries citing papers authored by R. Michael Linden

Since Specialization

Citations

This map shows the geographic impact of R. Michael Linden's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by R. Michael Linden with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites R. Michael Linden more than expected).

Fields of papers citing papers by R. Michael Linden

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by R. Michael Linden. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by R. Michael Linden. The network helps show where R. Michael Linden may publish in the future.

Co-authorship network of co-authors of R. Michael Linden

This figure shows the co-authorship network connecting the top 25 collaborators of R. Michael Linden. A scholar is included among the top collaborators of R. Michael Linden based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with R. Michael Linden. R. Michael Linden is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The Rare Disease Moonshot: Paradigms Shift, Translational Medicine, and Regulatory Science for the World's Rarest Conditions 2024 ·Clinical Pharmacology & Therapeutics ·(unknown), Solange Corriol‐Rohou, Marta del Álamo, (unknown), (unknown), Mathieu Boudes, Antón Ussi, K. Viel, R. Michael Linden, (unknown)	0
2	Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2 2021 ·Journal of Structural Biology ·Antonette Bennett, Joshua A. Hull, (unknown), Julie Tordo, Katie Moss, (unknown), Mario Mietzsch, (unknown), R. Michael Linden, Andrea Serio, Paul R. Chipman, Duncan Sousa, Felix Broecker, Peter H. Seeberger, Els Henckaerts, Robert McKenna, Mavis Agbandje‐McKenna	7
3	An Improved Adeno-Associated Virus Vector for Neurological Correction of the Mouse Model of Mucopolysaccharidosis IIIA 2019 ·Human Gene Therapy ·Anna L. Gray, Claire O’Leary, Aiyin Liao, (unknown), (unknown), Hélène F.E. Gleitz, Helen Parker, (unknown), Olivier Danos, Michaël Hocquemiller, (unknown), R. Michael Linden, Els Henckaerts, Rebecca Holley, Brian Bigger	14
4	Exchange of functional domains between a bacterial conjugative relaxase and the integrase of the human adeno-associated virus 2018 ·PLoS ONE ·(unknown), (unknown), (unknown), Martino Bardelli, Matxalen Llosa, Carlos Escalante, R. Michael Linden, Els Henckaerts	4
5	Determination of Adeno-associated Virus Rep DNA Binding Using Fluorescence Anisotropy 2017 ·BIO-PROTOCOL ·(unknown), (unknown), Martino Bardelli, (unknown), R. Michael Linden, Els Henckaerts, Carlos Escalante	2
6	Identification of a Functionally Relevant Adeno-Associated Virus Rep68 Oligomeric Interface 2016 ·Journal of Virology ·Martino Bardelli, (unknown), (unknown), R. Michael Linden, Carlos Escalante, Els Henckaerts	11
7	The Interdomain Linker of AAV-2 Rep68 Is an Integral Part of Its Oligomerization Domain: Role of a Conserved SF3 Helicase Residue in Oligomerization 2012 ·PLoS Pathogens ·(unknown), Martino Bardelli, John W. Burgner, (unknown), (unknown), Demet Kekilli, Jorge Mansilla‐Soto, R. Michael Linden, Carlos Escalante	25
8	Quantification of AAV Particle Titers by Infrared Fluorescence Scanning of Coomassie-Stained Sodium Dodecyl Sulfate–Polyacrylamide Gels 2012 ·Human Gene Therapy Methods ·Erik Kohlbrenner, Els Henckaerts, Kleopatra Rapti, Ronald E. Gordon, R. Michael Linden, Roger J. Hajjar, Thomas Weber	26
9	DNA Structure Modulates the Oligomerization Properties of the AAV Initiator Protein Rep68 2009 ·PLoS Pathogens ·Jorge Mansilla‐Soto, (unknown), William J. Rice, Shailee Arya, Carlos Escalante, R. Michael Linden	33
10	Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population breakdown → 2008 ·Nature ·Lei Yang, Mark H. Soonpaa, Eric Adler, Torsten K. Roepke, Steven Kattman, Marion Kennedy, Els Henckaerts, (unknown), Geoffrey W. Abbott, R. Michael Linden, Loren J. Field, Gordon Keller	1059
11	Effect of inhibition of dynein function and microtubule-altering drugs on AAV2 transduction 2007 ·Virology ·Sachiko Hirosue, (unknown), Nathalie Clément, Mathieu Nonnenmacher, (unknown), R. Michael Linden, Thomas Weber	28
12	Altering AAV tropism with mosaic viral capsids 2005 ·Molecular Therapy ·(unknown), (unknown), Nathalie Clément, Kenneth H. Warrington, Nicholas Muzyczka, R. Michael Linden, Thomas Weber	56
13	Transduction of Pancreatic Islets with Pseudotyped Adeno-Associated Virus: Effect of Viral Capsid and Genome Conversion 2005 ·Transplantation ·Nan Zhang, Nathalie Clément, Dongmei Chen, Shuang Fu, (unknown), (unknown), R. Michael Linden, Jonathan S. Bromberg	10
14	Residues within the B′ Motif Are Critical for DNA Binding by the Superfamily 3 Helicase Rep40 of Adeno-associated Virus Type 2 2004 ·Journal of Biological Chemistry ·(unknown), Amanda G. Blouin, (unknown), Jürgen A. Kleinschmidt, Aneel K. Aggarwal, Carlos Escalante, R. Michael Linden	40
15	Crystal Structure of the SF3 Helicase from Adeno-Associated Virus Type 2 2003 ·Structure ·Jeffrey A. James, Carlos Escalante, (unknown), Thomas A. Edwards, R. Michael Linden, Aneel K. Aggarwal	96
16	Identification of Active Site Residues of the Adeno-associated Virus Type 2 Rep Endonuclease 2003 ·Journal of Biological Chemistry ·(unknown), R. Michael Linden	19
17	Molecular Biology of Adeno-Associated Viruses 2000 ·PubMed ·R. Michael Linden, Kenneth I. Berns	37
18	The cryptic life style of adenoassociated virus 1995 ·BioEssays ·Kenneth I. Berns, R. Michael Linden	207
19	Expression of Neurospora crassa laccase under the control of the copper-inducible metallothionein-promoter 1992 ·Current Genetics ·Boris Schilling, R. Michael Linden, (unknown), Konrad Lerch	12
20	Regulation of laccase synthesis in induced Neurospora crassa cultures 1991 ·Current Genetics ·R. Michael Linden, Boris Schilling, Ursula A. Germann, Konrad Lerch	17

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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