Stephen J. Smerdon

14.2k citations

99 papers · 11.3k indexed · 5 hit papers · h-index 50

Molecular Biology top 0.5%
Cell Biology top 0.2%
Oncology top 2%
Immunology top 5%
Genetics top 2%

Co-authors: Michael B. Yaffe S.J. Gamblin Katrin Rittinger Steven G. Sedgwick Lewis C. Cantley Stephen P. Jackson Julie A. Clapperton Alastair Aitken
Topics: DNA Repair Mechanisms (19 papers)Ubiquitin and proteasome pathways (15 papers)Enzyme Structure and Function (15 papers)
Cited by: Cell Biology Molecular Biology Virology
Journals: Nature Science Cell
Partner nations: United Kingdom United States Tanzania

In The Last Decade

Stephen J. Smerdon

96 papers receiving 11.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity

1997 1.4k citations Michael B. Yaffe, Katrin Rittinger et al. Cell profile →
MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks

2005 853 citations Julie A. Clapperton, Michael B. Yaffe et al. Cell profile →
The ankyrin repeat: a diversity of interactions on a common structural framework

1999 663 citations Stephen J. Smerdon et al. profile →
The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain

2003 617 citations L.F. Haire, Stephen J. Smerdon et al. Cell profile →
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.

1994 290 citations Stephen J. Smerdon, Thomas A. Steitz et al. profile →

Peers

Countries citing papers authored by Stephen J. Smerdon

Since Specialization

Citations

This map shows the geographic impact of Stephen J. Smerdon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stephen J. Smerdon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stephen J. Smerdon more than expected).

Fields of papers citing papers by Stephen J. Smerdon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stephen J. Smerdon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stephen J. Smerdon. The network helps show where Stephen J. Smerdon may publish in the future.

Co-authorship network of co-authors of Stephen J. Smerdon

This figure shows the co-authorship network connecting the top 25 collaborators of Stephen J. Smerdon. A scholar is included among the top collaborators of Stephen J. Smerdon based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stephen J. Smerdon. Stephen J. Smerdon is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Uncoupling conformational states from activity in an allosteric enzyme 2017 ·Nature Communications ·(unknown),Cesira de Chiara,Kamila J. Pacholarz,Acely Garza-Garcı́a,R.W. Ogrodowicz,P.A. Walker,Perdita E. Barran,Stephen J. Smerdon,Luiz Pedro S. de Carvalho	19
2	HF‐Free Boc Synthesis of Peptide Thioesters for Ligation and Cyclization 2016 ·Angewandte Chemie International Edition ·(unknown),Fabienne Burlina,(unknown),Julian Downward,Jiejin Li,Stephen J. Smerdon,Martin Quibell,Peter D. White,John Offer	21
3	HF‐Free Boc Synthesis of Peptide Thioesters for Ligation and Cyclization 2016 ·Angewandte Chemie ·(unknown),Fabienne Burlina,(unknown),Julian Downward,Jiejin Li,Stephen J. Smerdon,Martin Quibell,Peter D. White,John Offer	3
4	Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains 2015 ·DNA repair ·(unknown),Timothy J. Nott,Geoff Kelly,Stuart L. Rulten,Keith W. Caldecott,Stephen J. Smerdon	22
5	Phosphorylation-Dependent PIH1D1 Interactions Define Substrate Specificity of the R2TP Cochaperone Complex 2014 ·Cell Reports ·Zuzana Hořejšı́,Lasse Stach,Thomas G. Flower,Dhira Joshi,Helen R. Flynn,(unknown),Nicola O’Reilly,R.W. Ogrodowicz,Stephen J. Smerdon,Simon J. Boulton	63
6	Activation of the Yeast Hippo Pathway by Phosphorylation-Dependent Assembly of Signaling Complexes 2013 ·DSpace@MIT (Massachusetts Institute of Technology) ·Daniel Lim,Lasse Stach,R.W. Ogrodowicz,Jamie M. Keck,Michele H. Jones,Catherine C. L. Wong,John R. Yates,Mark Winey,Stephen J. Smerdon,Jeremy M. Rock,Michael B. Yaffe,Angelika Amon	84
7	Substituted aminopyrimidine protein kinase B (PknB) inhibitors show activity against Mycobacterium tuberculosis 2012 ·Bioorganic & Medicinal Chemistry Letters ·Timothy M. Chapman,Nathalie Bouloc,Roger S. Buxton,(unknown),Kathryn Lougheed,Simon A. Osborne,Barbara Saxty,Stephen J. Smerdon,Debra L. Taylor,David Whalley	42
8	Structural and Functional Analysis of Phosphothreonine-Dependent FHA Domain Interactions 2010 ·Structure ·Simon Pennell,Sarah L. Westcott,M. Ortiz-Lombardı́a,(unknown),Jiejin Li,Timothy J. Nott,(unknown),Roger S. Buxton,Michael B. Yaffe,Chandra Verma,Stephen J. Smerdon	45
9	Access to phosphoproteins and glycoproteins through semi-synthesis, Native Chemical Ligation and N→S acyl transfer 2010 ·Organic & Biomolecular Chemistry ·Jinit Masania,Jiejin Li,Stephen J. Smerdon,Derek Macmillan	15
10	Function of the Nucleotide Exchange Activity of Vav1 in T Cell Development and Activation 2009 ·Science Signaling ·Alexander Saveliev,Lesley Vanes,(unknown),(unknown),Stephen J. Smerdon,Katrin Rittinger,Victor L. J. Tybulewicz	61
11	A Supramodular FHA/BRCT-Repeat Architecture Mediates Nbs1 Adaptor Function in Response to DNA Damage 2009 ·Cell ·(unknown),J. Ross Chapman,Julie A. Clapperton,L.F. Haire,Edgar Hartsuiker,Jiejin Li,Antony M. Carr,Stephen P. Jackson,Stephen J. Smerdon	133
12	Inhibition of Rac by the GAP Activity of Centralspindlin Is Essential for Cytokinesis 2008 ·Science ·Julie C. Canman,Lindsay Lewellyn,Kimberley Laband,Stephen J. Smerdon,Arshad Desai,Bruce Bowerman,Karen Oegema	135
13	The stimulatory RNA of the Visna-Maedi retrovirus ribosomal frameshifting signal is an unusual pseudoknot with an interstem element 2008 ·RNA ·Simon Pennell,(unknown),Andrew A. Flatt,Geoff Kelly,Stephen J. Smerdon,Ian Brierley	21
14	The Molecular Basis of FHA Domain:Phosphopeptide Binding Specificity and Implications for Phospho-Dependent Signaling Mechanisms 2000 ·Molecular Cell ·Daniel Durocher,Ian A. Taylor,(unknown),L.F. Haire,Sarah L. Westcott,Stephen P. Jackson,Stephen J. Smerdon,Michael B. Yaffe	358
15	The FHA Domain in DNA Repair and Checkpoint Signaling 2000 ·Cold Spring Harbor Symposia on Quantitative Biology ·Daniel Durocher,Stephen J. Smerdon,Michael B. Yaffe,Stephen P. Jackson	28
16	The structure of the GTPase-activating domain from p50rhoGAP 1997 ·Nature ·Tracey Barrett,Bing Xiao,(unknown),Guy Dodson,Steven B. Ludbrook,(unknown),S.J. Gamblin,(unknown),Stephen J. Smerdon,John F. Eccleston	96
17	Structure at 1.65 Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue 1997 ·Nature ·Katrin Rittinger,P.A. Walker,John F. Eccleston,Stephen J. Smerdon,S.J. Gamblin	418
18	Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways 1995 ·Nature ·Bing Xiao,Stephen J. Smerdon,David H. Jones,Guy Dodson,Yasmina Soneji,Alastair Aitken,S.J. Gamblin	404
19	Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion 1994 ·Structure ·Joachim Jäger,Stephen J. Smerdon,Jimin Wang,D.C. Boisvert,Thomas A. Steitz	57
20	Apomyoglobin as a molecular recognition surface: expression, reconstitution and crystallization of recombinant porcine myoglobin in Escherichia coli 1988 ·Protein Engineering Design and Selection ·Guy Dodson,Roderick E. Hubbard,Tom Oldfield,Stephen J. Smerdon,Anthony J. Wilkinson	22

About Stephen J. Smerdon

Stephen J. Smerdon is a scholar working on Cell Biology, Virology and Molecular Biology, having authored 99 papers that have together received 11.3k indexed citations. Recurring topics across this work include DNA Repair Mechanisms (19 papers), Ubiquitin and proteasome pathways (15 papers) and Enzyme Structure and Function (15 papers). The work is most often cited by research in Cell Biology (3.1k citations), Molecular Biology (9.1k citations) and Virology (556 citations). Stephen J. Smerdon has collaborated with scholars based in United Kingdom, United States and Tanzania. Frequent co-authors include Michael B. Yaffe, S.J. Gamblin, Katrin Rittinger, Steven G. Sedgwick, Lewis C. Cantley, Stephen P. Jackson, Julie A. Clapperton, Alastair Aitken, Duaa H. Mohammad and Stefano Volinia. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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