Roderick E. Hubbard

17.5k total citations · 6 hit papers
110 papers, 11.9k citations indexed

About

Roderick E. Hubbard is a scholar working on Molecular Biology, Computational Theory and Mathematics and Materials Chemistry. According to data from OpenAlex, Roderick E. Hubbard has authored 110 papers receiving a total of 11.9k indexed citations (citations by other indexed papers that have themselves been cited), including 90 papers in Molecular Biology, 38 papers in Computational Theory and Mathematics and 25 papers in Materials Chemistry. Recurrent topics in Roderick E. Hubbard's work include Protein Structure and Dynamics (38 papers), Computational Drug Discovery Methods (38 papers) and Enzyme Structure and Function (24 papers). Roderick E. Hubbard is often cited by papers focused on Protein Structure and Dynamics (38 papers), Computational Drug Discovery Methods (38 papers) and Enzyme Structure and Function (24 papers). Roderick E. Hubbard collaborates with scholars based in United Kingdom, Sweden and United States. Roderick E. Hubbard's co-authors include Edward N. Baker, A.C.W. Pike, A.M. Brzozowski, Jan-Ακε Gustafsson, Mats Carlquist, Zbigniew Dauter, Lars Öhman, Geoffrey L. Greene, Tomas Bonn and Owe Engström and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Roderick E. Hubbard

109 papers receiving 11.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Molecular basis of agonism and antagonism in the oestrogen receptor

1997 2.7k citations A.M. Brzozowski, A.C.W. Pike et al. profile →
Hydrogen bonding in globular proteins

1984 1.6k citations Edward N. Baker, Roderick E. Hubbard Progress in Biophysics and Molecular Biology profile →
Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport

1990 957 citations Roderick E. Hubbard et al. profile →
Twenty years on: the impact of fragments on drug discovery

2016 684 citations Daniel A. Erlanson, Stephen W. Fesik et al. Nature Reviews Drug Discovery profile →
The structure of 2Zn pig insulin crystals at 1.5 Å resolution

1988 558 citations Edward N. Baker, T.L. Blundell et al. Philosophical transactions of the Royal Society of London. Series B, Biological sciences profile →
rDock: A Fast, Versatile and Open Source Program for Docking Ligands to Proteins and Nucleic Acids

2014 409 citations Roderick E. Hubbard et al. profile →

Peers

Countries citing papers authored by Roderick E. Hubbard

Since Specialization

Citations

This map shows the geographic impact of Roderick E. Hubbard's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roderick E. Hubbard with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roderick E. Hubbard more than expected).

Fields of papers citing papers by Roderick E. Hubbard

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roderick E. Hubbard. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roderick E. Hubbard. The network helps show where Roderick E. Hubbard may publish in the future.

Co-authorship network of co-authors of Roderick E. Hubbard

This figure shows the co-authorship network connecting the top 25 collaborators of Roderick E. Hubbard. A scholar is included among the top collaborators of Roderick E. Hubbard based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Roderick E. Hubbard. Roderick E. Hubbard is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Targeting PTPN22 at Nonorthosteric Binding Sites─A Fragment Approach 2026 ·ACS Omega ·Paola Di Lello, (unknown), Ben Davis, Zoe Daniels, Thomas P. Garner, Lewis Gazzard, Richard Harris, Roderick E. Hubbard, (unknown), (unknown), (unknown), (unknown), Heather Simmonite, Nicholas J. Skelton, Mark Ultsch, (unknown), (unknown), Yoana N. Dimitrova, Kim Huard	0
2	Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors 2023 ·SLAS DISCOVERY ·Edward A. Fitzgerald, (unknown), (unknown), Hanna F. Klein, David J. Hamilton, V. Talibov, (unknown), (unknown), Maria T. Lindgren, Claes Holmgren, Ben Davis, Peter O’Brien, Maikel Wijtmans, Roderick E. Hubbard, Iwan J. P. de Esch, U. Helena Danielson	12
3	Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates 2022 ·RSC Medicinal Chemistry ·Simon Jones, James D. Firth, (unknown), Masakazu Atobe, Roderick E. Hubbard, David C. Blakemore, Claudia De Fusco, Simon C. C. Lucas, Stephen D. Roughley, Lewis R. Vidler, (unknown), Alison J.‐A. Woolford, Gail L. Wrigley, Peter O’Brien	4
4	Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V 2020 ·ACS Catalysis ·(unknown), (unknown), (unknown), Christian Roth, E.V. Blagova, Roderick E. Hubbard, Carme Rovira, G.J. Davies, Liang Wu	29
5	Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures 2020 ·Communications Chemistry ·Lisa Baker, A. Aimon, James B. Murray, A.E. Surgenor, Natalia Matassova, Stephen D. Roughley, P.M. Collins, T. Krojer, F. von Delft, Roderick E. Hubbard	12
6	Design and Synthesis of 56 Shape‐Diverse 3D Fragments 2020 ·Chemistry - A European Journal ·Thomas D. Downes, Simon Jones, Hanna F. Klein, (unknown), Masakazu Atobe, Paul S. Bond, James D. Firth, (unknown), (unknown), Roderick E. Hubbard, David C. Blakemore, Claudia De Fusco, Stephen D. Roughley, Lewis R. Vidler, (unknown), Alison J.‐A. Woolford, Gail L. Wrigley, Peter O’Brien	39
7	1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery 2019 ·Journal of Enzyme Inhibition and Medicinal Chemistry ·(unknown), Olivier Cala, (unknown), Marc Le Borgne, Roderick E. Hubbard, Isabelle Krimm	36
8	Increase of enzyme activity through specific covalent modification with fragments 2017 ·Chemical Science ·(unknown), Masakazu Atobe, James D. Firth, Paul S. Bond, G.J. Davies, Peter O’Brien, Roderick E. Hubbard	33
9	Twenty years on: the impact of fragments on drug discovery breakdown → 2016 ·Nature Reviews Drug Discovery ·Daniel A. Erlanson, Stephen W. Fesik, Roderick E. Hubbard, Wolfgang Jahnke, Harren Jhoti	684
10	Lead-oriented synthesis: Investigation of organolithium-mediated routes to 3-D scaffolds and 3-D shape analysis of a virtual lead-like library 2015 ·Bioorganic & Medicinal Chemistry ·Monique Lüthy, (unknown), (unknown), Masakazu Atobe, Paul S. Bond, Peter O’Brien, Roderick E. Hubbard, Ian J. S. Fairlamb	21
11	Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening 2011 ·Topics in current chemistry ·Stephen D. Roughley, Lisa Wright, Paul A. Brough, Andrew J. Massey, Roderick E. Hubbard	21
12	Fragment-based ligand discovery 2009 ·Molecular Interventions ·Marcus Fischer, Roderick E. Hubbard	40
13	The SeeDs Approach: Integrating Fragments into Drug Discovery 2007 ·Current Topics in Medicinal Chemistry ·Roderick E. Hubbard, Ben Davis, I‐Jen Chen, Martin J. Drysdale	57
14	Structure-based drug discovery : an overview 2006 ·Roderick E. Hubbard	32
15	Structure of Fab hGR-2 F6, a competitive antagonist of the glucagon receptor 2000 ·Acta Crystallographica Section D Biological Crystallography ·Lisa Wright, A.M. Brzozowski, Roderick E. Hubbard, A.C.W. Pike, S.M. Roberts, (unknown), I. Svendsen, Henrik Vissing, Robert P. Bywater	4
16	Structure of the protein tyrosine kinase domain of C-terminal Src kinase (CSK) in complex with staurosporine 1 1Edited by I. A. Wilson 1999 ·Journal of Molecular Biology ·Marieke Lamers, Alfred A. Antson, Roderick E. Hubbard, Richard Scott, D. H. Williams	120
17	HOOK: A program for finding novel molecular architectures that satisfy the chemical and steric requirements of a macromolecule binding site 1994 ·Proteins Structure Function and Bioinformatics ·Michael B. Eisen, Don C. Wiley, Martin Karplus, Roderick E. Hubbard	150
18	The structure of 2Zn pig insulin crystals at 1.5 Å resolution breakdown → 1988 ·Philosophical transactions of the Royal Society of London. Series B, Biological sciences ·Edward N. Baker, T.L. Blundell, J.F. Cutfield, (unknown), E.J. Dodson, (unknown), (unknown), Roderick E. Hubbard, (unknown), (unknown), (unknown), (unknown)	558
19	Apomyoglobin as a molecular recognition surface: expression, reconstitution and crystallization of recombinant porcine myoglobin in Escherichia coli 1988 ·Protein Engineering Design and Selection ·Guy Dodson, Roderick E. Hubbard, Tom Oldfield, Stephen J. Smerdon, Anthony J. Wilkinson	22
20	Hydrogen bonding in globular proteins breakdown → 1984 ·Progress in Biophysics and Molecular Biology ·Edward N. Baker, Roderick E. Hubbard	1570

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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