Roderick E. Hubbard

17.5k total citations · 6 hit papers
110 papers, 11.9k citations indexed

About

Roderick E. Hubbard is a scholar working on Molecular Biology, Computational Theory and Mathematics and Materials Chemistry. According to data from OpenAlex, Roderick E. Hubbard has authored 110 papers receiving a total of 11.9k indexed citations (citations by other indexed papers that have themselves been cited), including 90 papers in Molecular Biology, 38 papers in Computational Theory and Mathematics and 25 papers in Materials Chemistry. Recurrent topics in Roderick E. Hubbard's work include Protein Structure and Dynamics (38 papers), Computational Drug Discovery Methods (38 papers) and Enzyme Structure and Function (24 papers). Roderick E. Hubbard is often cited by papers focused on Protein Structure and Dynamics (38 papers), Computational Drug Discovery Methods (38 papers) and Enzyme Structure and Function (24 papers). Roderick E. Hubbard collaborates with scholars based in United Kingdom, Sweden and United States. Roderick E. Hubbard's co-authors include Edward N. Baker, A.C.W. Pike, A.M. Brzozowski, Jan-Ακε Gustafsson, Mats Carlquist, Zbigniew Dauter, Owe Engström, Lars Öhman, Tomas Bonn and Geoffrey L. Greene and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Roderick E. Hubbard

109 papers receiving 11.6k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Molecular basis of agonism and antagonism in the oestrogen receptor

1997 2.7k citations A.M. Brzozowski, A.C.W. Pike et al. profile →
Hydrogen bonding in globular proteins

1984 1.6k citations Edward N. Baker, Roderick E. Hubbard Progress in Biophysics and Molecular Biology profile →
Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport

1990 957 citations Roderick E. Hubbard et al. profile →
Twenty years on: the impact of fragments on drug discovery

2016 684 citations Roderick E. Hubbard et al. profile →
The structure of 2Zn pig insulin crystals at 1.5 Å resolution

1988 558 citations Edward N. Baker, T.L. Blundell et al. Philosophical transactions of the Royal Society of London. Series B, Biological sciences profile →
rDock: A Fast, Versatile and Open Source Program for Docking Ligands to Proteins and Nucleic Acids

2014 409 citations Xavier Barril, Roderick E. Hubbard et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Roderick E. Hubbard	7.7k	3.0k	2.5k	1.6k	1.5k	110	11.9k
Gregory L. Warren	13.8k 1.8×	2.0k 0.7×	2.1k 0.8×	4.2k 2.5×	1.4k 0.9×	32	18.8k
Maria J. Ramos	7.3k 1.0×	821 0.3×	1.7k 0.7×	2.1k 1.3×	1.3k 0.9×	436	13.6k
Zbigniew Dauter	9.9k 1.3×	2.9k 1.0×	694 0.3×	3.8k 2.3×	1.1k 0.7×	352	15.4k
Sunhwan Jo	12.6k 1.6×	999 0.3×	1.4k 0.6×	1.5k 0.9×	916 0.6×	69	17.0k
Pedro Alexandrino Fernandes	6.3k 0.8×	670 0.2×	1.6k 0.6×	2.0k 1.2×	1.1k 0.7×	376	11.8k
Malcolm W. MacArthur	18.7k 2.4×	2.4k 0.8×	1.3k 0.5×	5.7k 3.5×	1.7k 1.1×	20	25.5k
D. S. Moss	16.8k 2.2×	2.2k 0.7×	1.1k 0.4×	5.3k 3.2×	1.6k 1.1×	56	23.2k
Anton Simeonov	8.4k 1.1×	828 0.3×	2.4k 0.9×	658 0.4×	1.5k 1.0×	298	14.1k
Rebecca C. Wade	10.6k 1.4×	748 0.2×	2.7k 1.1×	2.6k 1.6×	956 0.6×	288	14.5k
Thomas Simonson	15.7k 2.0×	2.2k 0.7×	761 0.3×	4.7k 2.8×	1.3k 0.9×	128	20.4k

Countries citing papers authored by Roderick E. Hubbard

Since Specialization

Citations

This map shows the geographic impact of Roderick E. Hubbard's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Roderick E. Hubbard with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Roderick E. Hubbard more than expected).

Fields of papers citing papers by Roderick E. Hubbard

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Roderick E. Hubbard. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Roderick E. Hubbard. The network helps show where Roderick E. Hubbard may publish in the future.

Co-authorship network of co-authors of Roderick E. Hubbard

This figure shows the co-authorship network connecting the top 25 collaborators of Roderick E. Hubbard. A scholar is included among the top collaborators of Roderick E. Hubbard based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Roderick E. Hubbard. Roderick E. Hubbard is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Lello, Paola Di, Ben Davis, Zoe Daniels, et al.. (2026). Targeting PTPN22 at Nonorthosteric Binding Sites─A Fragment Approach. ACS Omega. 11(2). 3465–3480.

Fitzgerald, Edward A., Hanna F. Klein, David J. Hamilton, et al.. (2023). Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors. SLAS DISCOVERY. 29(1). 40–51. 12 indexed citations

Jones, Simon, James D. Firth, Masakazu Atobe, et al.. (2022). Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates. RSC Medicinal Chemistry. 13(12). 1614–1620. 4 indexed citations

Baker, Lisa, A. Aimon, James B. Murray, et al.. (2020). Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures. Communications Chemistry. 3(1). 122–122. 12 indexed citations

Downes, Thomas D., Simon Jones, Hanna F. Klein, et al.. (2020). Design and Synthesis of 56 Shape‐Diverse 3D Fragments. Chemistry - A European Journal. 26(41). 8969–8975. 39 indexed citations

Roth, Christian, E.V. Blagova, Roderick E. Hubbard, et al.. (2020). Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V. ACS Catalysis. 10(15). 8590–8596. 29 indexed citations

Cala, Olivier, et al.. (2019). 1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery. Journal of Enzyme Inhibition and Medicinal Chemistry. 34(1). 1218–1225. 36 indexed citations

Atobe, Masakazu, James D. Firth, Paul S. Bond, et al.. (2017). Increase of enzyme activity through specific covalent modification with fragments. Chemical Science. 8(11). 7772–7779. 33 indexed citations

Roth, Christian, et al.. (2014). Discovery of Selective Small‐Molecule Activators of a Bacterial Glycoside Hydrolase. Angewandte Chemie International Edition. 53(49). 13419–13423. 28 indexed citations

10.

Roth, Christian, et al.. (2014). Discovery of Selective Small‐Molecule Activators of a Bacterial Glycoside Hydrolase. Angewandte Chemie. 126(49). 13637–13641. 6 indexed citations

11.

Richardson, Christine M., D.S. Williamson, Martin J. Parratt, et al.. (2007). Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scoping. Bioorganic & Medicinal Chemistry Letters. 17(14). 3880–3885. 38 indexed citations

12.

Hubbard, Roderick E.. (2006). Structure-based drug discovery : an overview. 32 indexed citations

13.

Barril, Xavier, Paul A. Brough, Martin J. Drysdale, et al.. (2005). Structure-based discovery of a new class of Hsp90 inhibitors. Bioorganic & Medicinal Chemistry Letters. 15(23). 5187–5191. 58 indexed citations

14.

Wright, Lisa, Xavier Barril, Brian Dymock, et al.. (2004). Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms. Chemistry & Biology. 11(6). 775–785. 210 indexed citations

15.

Wright, Lisa, A.M. Brzozowski, Roderick E. Hubbard, et al.. (2000). Structure of Fab hGR-2 F6, a competitive antagonist of the glucagon receptor. Acta Crystallographica Section D Biological Crystallography. 56(5). 573–580. 4 indexed citations

16.

Verma, Chandra, et al.. (1998). Conformational change in the activation of lipase: An analysis in terms of low‐frequency normal modes. Protein Science. 7(6). 1359–1367. 32 indexed citations

17.

Hubbard, Roderick E.. (1997). Can drugs be designed?. Current Opinion in Biotechnology. 8(6). 696–700. 20 indexed citations

18.

Oldfield, Tom & Roderick E. Hubbard. (1994). Analysis of Cα geometry in protein structures. Proteins Structure Function and Bioinformatics. 18(4). 324–337. 69 indexed citations

19.

Baker, Edward N., et al.. (1988). The structure of 2Zn pig insulin crystals at 1.5 Å resolution. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 319(1195). 369–456. 558 indexed citations breakdown →

20.

Baker, Edward N. & Roderick E. Hubbard. (1984). Hydrogen bonding in globular proteins. Progress in Biophysics and Molecular Biology. 44(2). 97–179. 1570 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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