William C. Merrick

20.1k citations

179 papers · 16.3k indexed · 4 hit papers · h-index 71

Impact in

Molecular Biology top 0.1%
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- RNA modifications and cancer
- RNA regulation and disease
- PI3K/AKT/mTOR signaling in cancer
- Polyamine Metabolism and Applications
- CRISPR and Genetic Engineering
Cardiology and Cardiovascular Medicine top 1%
- Viral Infections and Immunology Research

Papers in

Molecular Biology 168
- RNA and protein synthesis mechanisms 130
- RNA Research and Splicing 58
- RNA modifications and cancer 57
- RNA regulation and disease 29
- Polyamine Metabolism and Applications 16
- Biochemical and Molecular Research 9
Cardiology and Cardiovascular Medicine 24
- Viral Infections and Immunology Research 24

Co-authors: Thomas Dever Nahum Sonenberg John W.B. Hershey George W. Rogers Anton A. Komar J. Grifo Manuel J. Glynias Richard D. Abramson
Journals: Journal of Biological Chemistry (64 papers)Proceedings of the National Academy of Sciences (14 papers)Molecular and Cellular Biology (8 papers)Archives of Biochemistry and Biophysics (7 papers)Methods in enzymology on CD-ROM/Methods in enzymology (6 papers)
Partner nations: United States Canada Russia

In The Last Decade

William C. Merrick

178 papers receiving 15.8k citations

Hit Papers

align trajectories log scale

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin 2010 · 717 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2010 Nature Chemical Biology
1992 Microbiological Reviews
1990 Molecular and Cellular Biology
1987 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by William C. Merrick

Since Specialization

Citations

This map shows the geographic impact of William C. Merrick's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William C. Merrick with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William C. Merrick more than expected).

Fields of papers citing papers by William C. Merrick

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William C. Merrick. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William C. Merrick. The network helps show where William C. Merrick may publish in the future.

Co-authors

The 25 scholars most cited alongside William C. Merrick, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with William C. Merrick Line = papers co-authored together William C. Merrick links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A Unique ISR Program Determines Cellular Responses to Chronic Stress Molecular Cell ·Bo‐Jhih Guan, Vincent van Hoef, Raul Jobava, Orna Elroy‐Stein, Leoš Shivaya Valášek, Marie Cargnello, Xing‐Huang Gao, Dawid Krokowski, William C. Merrick, Scot R. Kimball, Anton A. Komar, Antonis E. Koromilas, Anthony Wynshaw‐Boris, Ivan Topisirović, Ola Larsson, Maria Hatzoglou	2017	117
2	OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation Scientific Reports ·Huarong Chen, Renduo Song, Guohui Wang, Zonghui Ding, Chunying Yang, Jiawei Zhang, Zihua Zeng, Valentina Rubio, H. I. KALISH, Dominik Raub, Richard F. Neal, Laurie J. Minze, Prince Jeyabal, Eleni Karkamani, Bai Li, William C. Merrick, Shu Zheng, Zheng-Zheng Shi	2015	38
3	Translational Control during Endoplasmic Reticulum Stress beyond Phosphorylation of the Translation Initiation Factor eIF2α Journal of Biological Chemistry ·Bo-Jhih Guan, Dawid Krokowski, Mithu Majumder, Christine Schmotzer, Scot R. Kimball, William C. Merrick, Antonis E. Koromilas, Maria Hatzoglou	2014	123
4	A new framework for understanding IRES-mediated translation Gene ·Anton A. Komar, Barsanjit Mazumder, William C. Merrick	2012	66
5	Identification of an mRNP Complex Regulating Tumorigenesis at the Translational Elongation Step Molecular Cell ·George S. Hussey, Arindam Chaudhury, Andrea E. Dawson, Daniel J. Lindner, Charlotte R. Knudsen, Matthew C. J. Wilce, William C. Merrick, Philip H. Howe	2011	157
6	GTP-independent tRNA Delivery to the Ribosomal P-site by a Novel Eukaryotic Translation Factor Journal of Biological Chemistry ·Sergey E. Dmitriev, Ilya M. Terenin, Dmitry E. Andreev, Pavel A. Ivanov, A.L. Bruni, William C. Merrick, Ivan N. Shatsky	2010	128
7	An efficient in vitro translation system from mammalian cells lacking the translational inhibition caused by eIF2 phosphorylation RNA ·Anna K. Gragas, Chuanping Wang, Mithu Majumder, Anton A. Komar, Martin D. Snider, William C. Merrick, Randal J. Kaufman, Maria Hatzoglou	2008	35
8	MicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4F Science ·Géraldine Mathonnet, Marc R. Fabian, Yuri V. Svitkin, Armen Parsyan, Laurent Huck, Takayuki Murata, Stefano Biffo, William C. Merrick, Edward Darżynkiewicz, Ramesh S. Pillai, Witold Filipowicz, Thomas F. Duchaîne, Nahum Sonenberg	2007	403
9	6 Translation Initiation Via Cellular Internal Ribosome Entry Sites Cold Spring Harbor Monograph Archive ·Orna Elroy‐Stein, William C. Merrick	2007	34
10	Eukaryotic protein synthesis inhibitors identified by comparison of cytotoxicity profiles RNA ·Jenny Chan, Shakila Nargis Khan, Isabelle Harvey, William C. Merrick, Jerry Pelletier	2004	52
11	The Transformation Suppressor Pdcd4 Is a Novel Eukaryotic Translation Initiation Factor 4A Binding Protein That Inhibits Translation Molecular and Cellular Biology ·Hsin‐Sheng Yang, Aaron P. Jansen, Anton A. Komar, Xiaojing Zheng, William C. Merrick, Sylvain V. Costes, Stephen Lockett, Nahum Sonenberg, Nancy H. Colburn	2002	420
12	Positive and Negative Effects of the Major Mammalian Messenger Ribonucleoprotein p50 on Binding of 40 S Ribosomal Subunits to the Initiation Codon of β-Globin mRNA Journal of Biological Chemistry ·Andrey V. Pisarev, M. Gui, Adri A.M. Thomas, William C. Merrick, Lev P. Ovchinnikov, Ivan N. Shatsky	2002	47
13	Regulation of Internal Ribosome Entry Site-mediated Translation by Eukaryotic Initiation Factor-2α Phosphorylation and Translation of a Small Upstream Open Reading Frame Journal of Biological Chemistry ·James Fernandez, İbrahim Yaman, William C. Merrick, Antonis E. Koromilas, Ronald C. Wek, Et al. Khalid Altarawneh, Jack O. Hensold, Maria Hatzoglou	2002	89
14	3 The Protein Biosynthesis, Elongation Cycle Cold Spring Harbor Monograph Archive ·William C. Merrick, Jens Nyborg	2000	57
15	2 The Pathway and Mechanism of Initiation of Protein Synthesis Cold Spring Harbor Monograph Archive ·John W.B. Hershey, William C. Merrick	2000	104
16	Conservation and Diversity of Eukaryotic Translation Initiation Factor eIF3 Journal of Biological Chemistry ·Katsura Asano, Terri Goss Kinzy, William C. Merrick, John W.B. Hershey	1997	123
17	2 The Pathway and Mechanism of Eukaryotic Protein Synthesis Cold Spring Harbor Monograph Archive ·William C. Merrick, John W.B. Hershey	1996	198
18	Further Biochemical Characterization of Rabbit Reticulocyte eIF-4B Archives of Biochemistry and Biophysics ·Diane L. Hughes, Thomas Dever, William C. Merrick	1993	11
19	Affinity labeling of protein synthesis factors Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States) ·Donald D. Anthony, Thomas Dever, Richard D. Abramson, Ann Webb, William C. Merrick	1986	1
20	[8] Purification of protein synthesis initiation factors from rabbit reticulocytes Methods in enzymology on CD-ROM/Methods in enzymology ·William C. Merrick	1979	89

About William C. Merrick

William C. Merrick is a scholar working on Molecular Biology, Cardiology and Cardiovascular Medicine, Microbiology, Cell Biology and Immunology and Allergy, having authored 179 papers that have together received 16.3k indexed citations. Recurring topics across this work include RNA and protein synthesis mechanisms (130 papers), RNA Research and Splicing (58 papers), RNA modifications and cancer (57 papers), RNA regulation and disease (29 papers), Viral Infections and Immunology Research (24 papers), Polyamine Metabolism and Applications (16 papers), Biochemical and Molecular Research (9 papers) and Bacteriophages and microbial interactions (9 papers). The work is most often cited by research in Molecular Biology (13.9k citations), Cardiology and Cardiovascular Medicine (1.9k citations), Cell Biology (1.2k citations), Aging (111 citations) and Cancer Research (911 citations). William C. Merrick has collaborated with scholars based in United States, Canada and Russia. Frequent co-authors include Thomas Dever, Nahum Sonenberg, John W.B. Hershey, George W. Rogers, Anton A. Komar, J. Grifo, Manuel J. Glynias, Richard D. Abramson, Aaron J. Shatkin and M A Morgan. Their work appears in journals such as Journal of Biological Chemistry, Proceedings of the National Academy of Sciences, Molecular and Cellular Biology, Archives of Biochemistry and Biophysics and Methods in enzymology on CD-ROM/Methods in enzymology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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