Anastassis Perrakis

21.5k total citations · 7 hit papers
157 papers, 15.9k citations indexed

About

Anastassis Perrakis is a scholar working on Molecular Biology, Materials Chemistry and Cell Biology. According to data from OpenAlex, Anastassis Perrakis has authored 157 papers receiving a total of 15.9k indexed citations (citations by other indexed papers that have themselves been cited), including 137 papers in Molecular Biology, 51 papers in Materials Chemistry and 35 papers in Cell Biology. Recurrent topics in Anastassis Perrakis's work include Enzyme Structure and Function (51 papers), Protein Structure and Dynamics (37 papers) and Sphingolipid Metabolism and Signaling (20 papers). Anastassis Perrakis is often cited by papers focused on Enzyme Structure and Function (51 papers), Protein Structure and Dynamics (37 papers) and Sphingolipid Metabolism and Signaling (20 papers). Anastassis Perrakis collaborates with scholars based in Netherlands, United Kingdom and Germany. Anastassis Perrakis's co-authors include Victor S. Lamzin, Richard J. Morris, Titia K. Sixma, Keith S. Wilson, Serge X. Cohen, Robbie P. Joosten, Gerrit G. Langer, Garib N. Murshudov, Wouter H. Moolenaar and Fei Long and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Anastassis Perrakis

154 papers receiving 15.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Automated protein model building combined with iterative structure refinement.

1999 2.3k citations Anastassis Perrakis, Richard J. Morris et al. profile →
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

2008 1.4k citations Serge X. Cohen, Victor S. Lamzin et al. profile →
ThePDB_REDOserver for macromolecular structure model optimization

2014 632 citations Robbie P. Joosten, Anastassis Perrakis et al. profile →
RNA-Binding Protein Dnd1 Inhibits MicroRNA Access to Target mRNA

2007 591 citations Martijn Kedde, Bijan Boldajipour et al. Cell profile →
Developments in theCCP4 molecular-graphics project

2004 520 citations Serge Cohen, Anastassis Perrakis et al. profile →
The crystal structure of DNA mismatch repair protein MutS binding to a G·T mismatch

2000 520 citations Anastassis Perrakis et al. profile →
AlphaFill: enriching AlphaFold models with ligands and cofactors

2022 268 citations Maarten L. Hekkelman, Ida de Vries et al. Nature Methods profile →

Peers

Countries citing papers authored by Anastassis Perrakis

Since Specialization

Citations

This map shows the geographic impact of Anastassis Perrakis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Anastassis Perrakis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Anastassis Perrakis more than expected).

Fields of papers citing papers by Anastassis Perrakis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Anastassis Perrakis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Anastassis Perrakis. The network helps show where Anastassis Perrakis may publish in the future.

Co-authorship network of co-authors of Anastassis Perrakis

This figure shows the co-authorship network connecting the top 25 collaborators of Anastassis Perrakis. A scholar is included among the top collaborators of Anastassis Perrakis based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Anastassis Perrakis. Anastassis Perrakis is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Halogen bonds between ligands and proteins: Can we use them in validation? 2025 ·Protein Science ·Ida de Vries, (unknown), Anastassis Perrakis, Robbie P. Joosten	1
2	Unlocking the signaling potential of GPI-anchored proteins through lipolytic cleavage 2025 ·Trends in Cell Biology ·(unknown), Elisa Matas-Rico, Anastassis Perrakis, Wouter H. Moolenaar	1
3	Caskin2 is a novel talin- and Abi1-binding protein that promotes cell motility 2024 ·Journal of Cell Science ·Wei Wang, Paul Atherton, Maaike Kreft, Lisa te Molder, (unknown), Liesbeth Hoekman, Patrick H. N. Celie, Robbie P. Joosten, Reinhard Fässler, Anastassis Perrakis, Arnoud Sonnenberg	1
4	AlphaFill: enriching AlphaFold models with ligands and cofactors breakdown → 2022 ·Nature Methods ·Maarten L. Hekkelman, Ida de Vries, Robbie P. Joosten, Anastassis Perrakis	268
5	Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin 2022 ·The Journal of Cell Biology ·(unknown), (unknown), (unknown), Mathias Girbig, Franziska Müller, Sabine Wohlgemuth, Andreas Brockmeyer, Stefano Maffini, Petra Janning, Ingrid R. Vetter, Andrew P. Carter, Anastassis Perrakis, (unknown)	16
6	Posttranslational modification of microtubules by the MATCAP detyrosinase 2022 ·Science ·(unknown), (unknown), Athanassios Adamopoulos, (unknown), (unknown), Lisa G. van den Hengel, Ji‐Ying Song, Onno B. Bleijerveld, Joppe Nieuwenhuis, Tatjana Heidebrecht, Linda Henneman, Marie‐Jo Moutin, Marin Barišić, Stavros Taraviras, Anastassis Perrakis, Thijn R. Brummelkamp	43
7	Conserved residues Glu37 and Trp229 play an essential role in protein folding of β‐lactamase 2021 ·FEBS Journal ·(unknown), (unknown), (unknown), (unknown), Anastassis Perrakis, Marcellus Ubbink	8
8	Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery 2021 ·Journal of Visualized Experiments ·(unknown), Alexander Fish, (unknown), Sridhar Sreeramulu, Christian Richter, Nadide Altincekic, Harald Schwalbe, Hans Wienk, Anastassis Perrakis	4
9	Imaging Autotaxin In Vivo with ¹⁸F-Labeled Positron Emission Tomography Ligands 2021 ·Journal of Medicinal Chemistry ·Xiaoyun Deng, Fernando Salgado-Polo, Tuo Shao, Zhiwei Xiao, Richard Van, Jiahui Chen, Jian Rong, Ahmed Haider, Yihan Shao, Lee Josephson, Anastassis Perrakis, Steven H. Liang	4
10	Sequence-dependent trafficking and activity of GDE2, a GPI-specific phospholipase promoting neuronal differentiation 2020 ·Journal of Cell Science ·Fernando Salgado-Polo, (unknown), Bram van den Broek, Kees Jalink, Daniela Leyton-Puig, Anastassis Perrakis, Wouter H. Moolenaar, Elisa Matas-Rico	11
11	Characterization and structure determination of a llama-derived nanobody targeting the J-base binding protein 1 2018 ·Acta Crystallographica Section F Structural Biology Communications ·Bart van Beusekom, Tatjana Heidebrecht, Athanassios Adamopoulos, Alexander Fish, Els Pardon, Jan Steyaert, Robbie P. Joosten, Anastassis Perrakis	2
12	Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA–mDia2 signaling and filopodium formation 2018 ·Journal of Biological Chemistry ·Elisabetta Argenzio, Jeffrey Klarenbeek, Katarzyna M. Kedziora, Leila Nahidiazar, Tadamoto Isogai, Anastassis Perrakis, Kees Jalink, Wouter H. Moolenaar, Metello Innocenti	13
13	Vasohibins encode tubulin detyrosinating activity 2017 ·Science ·Joppe Nieuwenhuis, Athanassios Adamopoulos, Onno B. Bleijerveld, Abdelghani Mazouzi, Elmer Stickel, Patrick H. N. Celie, Maarten Altelaar, Puck Knipscheer, Anastassis Perrakis, Vincent A. Blomen, Thijn R. Brummelkamp	178
14	Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells 2017 ·eLife ·(unknown), Elisa Matas-Rico, Koen van de Wetering, Daniela Leyton-Puig, Katarzyna M. Kedziora, Valentina De Lorenzi, (unknown), Bram van den Broek, Kees Jalink, Nicolai Sidénius, Anastassis Perrakis, Wouter H. Moolenaar	42
15	The first step of peptide selection in antigen presentation by MHC class I molecules 2015 ·Proceedings of the National Academy of Sciences ·Malgorzata Garstka, Alexander Fish, Patrick H. N. Celie, Robbie P. Joosten, George M. C. Janssen, Ilana Berlin, (unknown), (unknown), Lennert Janssen, Huib Ovaa, Peter A. van Veelen, Anastassis Perrakis, Jacques Neefjes	66
16	Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling 2015 ·Science ·Yoshitaka Hiruma, Carlos Sacristán, Spyridon T. Pachis, Athanassios Adamopoulos, (unknown), Marcellus Ubbink, Eleonore von Castelmur, Anastassis Perrakis, Geert J.P.L. Kops	165
17	Automatic rebuilding and optimization of crystallographic structures in the Protein Data Bank 2011 ·Bioinformatics ·Robbie P. Joosten, (unknown), Serge X. Cohen, Gert Vriend, Anastassis Perrakis	81
18	RNA-Binding Protein Dnd1 Inhibits MicroRNA Access to Target mRNA breakdown → 2007 ·Cell ·Martijn Kedde, (unknown), Bijan Boldajipour, Joachim A.F. Oude Vrielink, Krasimir Slanchev, Carlos le Sage, Remco Nagel, P. Mathijs Voorhoeve, (unknown), Ulf Andersson Ørom, Anders H. Lund, Anastassis Perrakis, Erez Raz, Reuven Agami	591
19	Inhibition of Autotaxin by Lysophosphatidic Acid and Sphingosine 1-Phosphate 2005 ·Journal of Biological Chemistry ·Laurens A. van Meeteren, Paula Ruurs, Evangelos Christodoulou, James W. Goding, Hideo Takakusa, Kazuya Kikuchi, Anastassis Perrakis, Tetsuo Nagano, Wouter H. Moolenaar	164
20	Breaking good resolutions with ARP/wARP 2003 ·Journal of Synchrotron Radiation ·Richard J. Morris, Petrus H. Zwart, Serge Cohen, Francisco J. Fernández, (unknown), (unknown), Clemens Vonrhein, Anastassis Perrakis, Victor S. Lamzin	125

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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