Stephen P. Jackson

87.6k total citations · 34 hit papers
350 papers, 66.5k citations indexed

About

Stephen P. Jackson is a scholar working on Molecular Biology, Oncology and Genetics. According to data from OpenAlex, Stephen P. Jackson has authored 350 papers receiving a total of 66.5k indexed citations (citations by other indexed papers that have themselves been cited), including 301 papers in Molecular Biology, 97 papers in Oncology and 61 papers in Genetics. Recurrent topics in Stephen P. Jackson's work include DNA Repair Mechanisms (206 papers), Genomics and Chromatin Dynamics (69 papers) and CRISPR and Genetic Engineering (68 papers). Stephen P. Jackson is often cited by papers focused on DNA Repair Mechanisms (206 papers), Genomics and Chromatin Dynamics (69 papers) and CRISPR and Genetic Engineering (68 papers). Stephen P. Jackson collaborates with scholars based in United Kingdom, United States and France. Stephen P. Jackson's co-authors include Jiří Bártek, Graeme C.M. Smith, Kum Kum Khanna, Julia Coates, Daniel Durocher, Tanya Gottlieb, Andrew N. Blackford, Sophie E. Polo, Robert Tjian and Niall M.B. Martin and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Stephen P. Jackson

346 papers receiving 65.6k citations

Hit Papers

Targeting the DNA repair defect in BRCA mutant ... 1988 2026 2000 2013 2005 2009 2003 2001 2017 1000 2.0k 3.0k 4.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
    2005 4.8k citations Niall M.B. Martin, Stephen P. Jackson et al. profile →
  2. The DNA-damage response in human biology and disease
    2009 4.4k citations Stephen P. Jackson et al. profile →
  3. A DNA damage checkpoint response in telomere-initiated senescence
    2003 2.1k citations Fabrizio d’Adda di Fagagna, Stephen P. Jackson et al. profile →
  4. DNA double-strand breaks: signaling, repair and the cancer connection
    2001 1.9k citations Stephen P. Jackson et al. profile →
  5. ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response
    2017 1.3k citations Andrew N. Blackford, Stephen P. Jackson Molecular Cell profile →
  6. Human CtIP promotes DNA end resection
    2007 1.0k citations Julia Coates, Stephen P. Jackson et al. profile →
  7. The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
    1993 1.0k citations Stephen P. Jackson et al. profile →
  8. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
    2005 983 citations Julia Coates, Stephen P. Jackson et al. profile →
  9. Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM
    2004 983 citations Niall M.B. Martin, Stephen P. Jackson et al. profile →
  10. Sensing and repairing DNA double-strand breaks
    2002 886 citations Stephen P. Jackson profile →
  11. Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
    2011 867 citations Sophie E. Polo, Stephen P. Jackson profile →
  12. MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
    2005 853 citations Manuel Stucki, Michael B. Yaffe et al. profile →
  13. Regulation of p53 in response to DNA damage
    1999 837 citations Stephen P. Jackson et al. profile →
  14. ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
    2005 832 citations Stephen P. Jackson et al. profile →
  15. O-glycosylation of eukaryotic transcription factors: Implications for mechanisms of transcriptional regulation
    1988 794 citations Stephen P. Jackson et al. profile →
  16. The DNA-dependent protein kinase
    1999 741 citations Stephen P. Jackson et al. profile →
  17. Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation
    1995 725 citations Frederick W. Alt, Penny A. Jeggo et al. profile →
  18. Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase
    2007 719 citations Stephen P. Jackson, Daniel Durocher et al. Science profile →
  19. A Pathway of Double-Strand Break Rejoining Dependent upon ATM, Artemis, and Proteins Locating to γ-H2AX Foci
    2004 683 citations Aidan J. Doherty, Stephen P. Jackson et al. Molecular Cell profile →
  20. The MRE11 complex: at the crossroads of DNA repair and checkpoint signalling
    2002 680 citations Stephen P. Jackson et al. profile →
  21. Deubiquitylating enzymes and drug discovery: emerging opportunities
    2017 657 citations Jeanine A. Harrigan, Xavier Jacq et al. Nature Reviews Drug Discovery profile →
  22. DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
    1995 637 citations Stephen P. Jackson et al. profile →
  23. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase
    1990 616 citations Stephen P. Jackson et al. profile →
  24. Small-molecule–induced DNA damage identifies alternative DNA structures in human genes
    2012 589 citations Raphaël Rodriguez, Charles R. Bradshaw et al. profile →
  25. XLF Interacts with the XRCC4-DNA Ligase IV Complex to Promote DNA Nonhomologous End-Joining
    2006 574 citations Stephen P. Jackson et al. profile →
  26. Interfaces Between the Detection, Signaling, and Repair of DNA Damage
    2002 562 citations John Rouse, Stephen P. Jackson Science profile →
  27. Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination
    1994 555 citations Frederick W. Alt, Stephen P. Jackson et al. Science profile →
  28. A role for Saccharomyces cerevisiae histone H2A in DNA repair
    2000 522 citations Stephen P. Jackson et al. profile →
  29. Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining
    2010 513 citations Julia Coates, Sophie E. Polo et al. profile →
  30. Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks
    2014 497 citations Christine K. Schmidt, Stephen P. Jackson et al. profile →
  31. Regulation of DNA Damage Responses by Ubiquitin and SUMO
    2013 481 citations Stephen P. Jackson, Daniel Durocher Molecular Cell profile →
  32. Targeting DNA Repair in Cancer: Beyond PARP Inhibitors
    2016 458 citations Stephen P. Jackson et al. profile →
  33. A Compendium of Mutational Signatures of Environmental Agents
    2019 358 citations Stephen P. Jackson et al. profile →
  34. Predicting the mutations generated by repair of Cas9-induced double-strand breaks
    2018 348 citations Stephen P. Jackson et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Stephen P. Jackson United Kingdom 119 56.5k 20.9k 9.8k 7.3k 5.6k 350 66.5k
Jiří Bártek Denmark 107 41.7k 0.7× 23.3k 1.1× 9.5k 1.0× 4.7k 0.6× 8.3k 1.5× 383 54.0k
J. Wade Harper United States 120 48.8k 0.9× 19.5k 0.9× 7.1k 0.7× 5.0k 0.7× 11.7k 2.1× 307 62.5k
Stephen J. Elledge United States 152 76.0k 1.3× 27.7k 1.3× 13.9k 1.4× 10.1k 1.4× 15.0k 2.7× 367 93.0k
Charles J. Sherr United States 96 39.2k 0.7× 30.4k 1.5× 6.9k 0.7× 6.0k 0.8× 7.6k 1.4× 271 58.0k
Paul Tempst United States 143 62.1k 1.1× 8.3k 0.4× 7.6k 0.8× 6.6k 0.9× 8.7k 1.6× 320 80.8k
Scott W. Lowe United States 123 50.1k 0.9× 23.0k 1.1× 16.9k 1.7× 4.2k 0.6× 5.1k 0.9× 325 69.6k
David Beach United States 100 34.4k 0.6× 20.2k 1.0× 5.3k 0.5× 3.5k 0.5× 9.2k 1.6× 247 47.3k
Hediye Erdjument‐Bromage United States 125 53.4k 0.9× 7.4k 0.4× 6.0k 0.6× 5.5k 0.7× 7.7k 1.4× 285 68.1k
Jan H.J. Hoeijmakers Netherlands 107 38.1k 0.7× 7.8k 0.4× 8.4k 0.9× 5.8k 0.8× 2.8k 0.5× 399 48.0k
Tony Hunter United States 155 77.6k 1.4× 23.2k 1.1× 8.6k 0.9× 9.5k 1.3× 17.5k 3.1× 504 103.8k

Countries citing papers authored by Stephen P. Jackson

Since Specialization
Citations

This map shows the geographic impact of Stephen P. Jackson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stephen P. Jackson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stephen P. Jackson more than expected).

Fields of papers citing papers by Stephen P. Jackson

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stephen P. Jackson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stephen P. Jackson. The network helps show where Stephen P. Jackson may publish in the future.

Co-authorship network of co-authors of Stephen P. Jackson

This figure shows the co-authorship network connecting the top 25 collaborators of Stephen P. Jackson. A scholar is included among the top collaborators of Stephen P. Jackson based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stephen P. Jackson. Stephen P. Jackson is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Kochenova, Olga V., Giuseppina D’Alessandro, Domenic Pilger, et al.. (2025). USP37 prevents premature disassembly of stressed replisomes by TRAIP. Nature Communications. 16(1). 5333–5333.
2.
Bader, Aldo S., et al.. (2024). TDP1 splice-site mutation causes HAP1 cell hypersensitivity to topoisomerase I inhibition. Nucleic Acids Research. 53(2). 2 indexed citations
3.
Sagawa, Zachary K., Azra Blazevic, Janice Tennant, et al.. (2023). Safety and immunogenicity of a thermostable ID93 + GLA-SE tuberculosis vaccine candidate in healthy adults. Nature Communications. 14(1). 1138–1138. 20 indexed citations
4.
Sun, Dawei, Oriol Llorà-Batlle, Jelle van den Ameele, et al.. (2022). SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling. The EMBO Journal. 41(21). e111338–e111338. 23 indexed citations
5.
Jenner, Matthew, Thomas A. Jowitt, Christian Loc’h, et al.. (2022). Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining. Nucleic Acids Research. 50(8). 4732–4754. 12 indexed citations
6.
Herzog, Mareike, Israel Salguero, Jonas Warringer, et al.. (2021). Mutagenic mechanisms of cancer-associated DNA polymerase ϵ alleles. Nucleic Acids Research. 49(7). 3919–3931. 13 indexed citations
7.
Harrigan, Jeanine A., Xavier Jacq, Niall M.B. Martin, & Stephen P. Jackson. (2017). Deubiquitylating enzymes and drug discovery: emerging opportunities. Nature Reviews Drug Discovery. 17(1). 57–78. 657 indexed citations breakdown →
8.
Puddu, Fabio, Ilaria Guerini, Hengyao Niu, et al.. (2015). Synthetic viability genomic screening defines Sae2 function in DNA repair. The EMBO Journal. 34(11). 1509–1522. 36 indexed citations
9.
Ochi, Takashi, Andrew N. Blackford, Julia Coates, et al.. (2015). PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science. 347(6218). 185–188. 237 indexed citations
10.
Larrieu, Delphine, Sébastien Britton, Mehmet Demir, Raphaël Rodriguez, & Stephen P. Jackson. (2014). Chemical Inhibition of NAT10 Corrects Defects of Laminopathic Cells. Science. 344(6183). 527–532. 294 indexed citations
11.
Britton, Sébastien, Julia Coates, & Stephen P. Jackson. (2013). A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair. The Journal of Cell Biology. 202(3). 579–595. 206 indexed citations
12.
Harrigan, Jeanine A., Rimma Belotserkovskaya, Julia Coates, et al.. (2011). Replication stress induces 53BP1-containing OPT domains in G1 cells. The Journal of Cell Biology. 193(1). 97–108. 266 indexed citations
13.
Hájková, Petra, et al.. (2010). Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway. Science. 329(5987). 78–82. 358 indexed citations
14.
Hořejšı́, Zuzana, Nicola Wiechens, Sophie E. Polo, et al.. (2009). Poly(ADP-ribose)–Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1. Science. 325(5945). 1240–1243. 467 indexed citations
15.
Xie, Anyong, Andrea J. Hartlerode, Manuel Stucki, et al.. (2007). Distinct Roles of Chromatin-Associated Proteins MDC1 and 53BP1 in Mammalian Double-Strand Break Repair. Molecular Cell. 28(6). 1045–1057. 182 indexed citations
16.
Weller, Geoffrey R., Boris Kysela, Rajat Roy, et al.. (2002). Identification of a DNA Nonhomologous End-Joining Complex in Bacteria. Science. 297(5587). 1686–1689. 252 indexed citations
17.
Rouse, John & Stephen P. Jackson. (2002). Lcd1p Recruits Mec1p to DNA Lesions In Vitro and In Vivo. Molecular Cell. 9(4). 857–869. 150 indexed citations
18.
Durocher, Daniel, Ian A. Taylor, L.F. Haire, et al.. (2000). The Molecular Basis of FHA Domain:Phosphopeptide Binding Specificity and Implications for Phospho-Dependent Signaling Mechanisms. Molecular Cell. 6(5). 1169–1182. 358 indexed citations
19.
Critchlow, Susan E., Richard P. Bowater, & Stephen P. Jackson. (1997). Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV. Current Biology. 7(8). 588–598. 386 indexed citations
20.
Jongmans, Wim, et al.. (1996). The role of Ataxia telangiectasia and the DNA-dependent protein kinase in the p53-mediated cellular response to ionising radiation.. PubMed. 13(6). 1133–8. 39 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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