Simon Heales

16.1k total citations · 2 hit papers
180 papers, 10.6k citations indexed

About

Simon Heales is a scholar working on Molecular Biology, Physiology and Clinical Biochemistry. According to data from OpenAlex, Simon Heales has authored 180 papers receiving a total of 10.6k indexed citations (citations by other indexed papers that have themselves been cited), including 89 papers in Molecular Biology, 73 papers in Physiology and 69 papers in Clinical Biochemistry. Recurrent topics in Simon Heales's work include Metabolism and Genetic Disorders (68 papers), Mitochondrial Function and Pathology (54 papers) and Nitric Oxide and Endothelin Effects (34 papers). Simon Heales is often cited by papers focused on Metabolism and Genetic Disorders (68 papers), Mitochondrial Function and Pathology (54 papers) and Nitric Oxide and Endothelin Effects (34 papers). Simon Heales collaborates with scholars based in United Kingdom, Spain and United States. Simon Heales's co-authors include John M. Land, Juan P. Bolaños, John B. Clark, Iain P. Hargreaves, Victoria C. Stewart, M. P. Brand, Peter T. Clayton, Iain P. Hargreaves, Matthew E. Gegg and Nathan Davies and has published in prestigious journals such as The Lancet, Journal of Biological Chemistry and Circulation.

In The Last Decade

Simon Heales

179 papers receiving 10.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Association between mitochondrial dysfunction and severity and outcome of septic shock

2002 1.1k citations David Brealey, M. P. Brand et al. The Lancet profile →
Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains

2012 440 citations Simon Heales et al. profile →

Peers

Countries citing papers authored by Simon Heales

Since Specialization

Citations

This map shows the geographic impact of Simon Heales's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon Heales with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon Heales more than expected).

Fields of papers citing papers by Simon Heales

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon Heales. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon Heales. The network helps show where Simon Heales may publish in the future.

Co-authorship network of co-authors of Simon Heales

This figure shows the co-authorship network connecting the top 25 collaborators of Simon Heales. A scholar is included among the top collaborators of Simon Heales based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Simon Heales. Simon Heales is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Multi-omic analysis reveals lipid dysregulation associated with mitochondrial dysfunction in parkinson’s disease brain 2025 ·Nature Communications ·Jenny Hällqvist, Christina E. Toomey, Rui Pinto, (unknown), Ivan Doykov, Anna I. Wernick, Mesfer Al Shahrani, James R. Evans, (unknown), Simon Pope, Simon Heales, Simon Eaton, Kevin Mills, Sonia Gandhi, Wendy Heywood	0
2	Clinical Features, Biochemistry, Imaging, and Treatment Response in a Single-Center Cohort With Coenzyme Q ₁₀ Biosynthesis Disorders 2024 ·Neurology Genetics ·(unknown), Sniya Sudhakar, Amanda Lam, (unknown), Philippa B. Mills, Paul Gissen, Alice Gardham, (unknown), Jane Hassell, Simon Heales, Shamima Rahman	1
3	Reply to Maase et al. Comment on “Jones et al. Application of a Novel Algorithm for Expanding Newborn Screening for Inherited Metabolic Disorders across Europe. Int. J. Neonatal Screen. 2022, 8, 20” 2023 ·International Journal of Neonatal Screening ·Simon Jones, David Cheillan, Anupam Chakrapani, Heather J. Church, Simon Heales, (unknown), (unknown), (unknown), (unknown), Alberto Burlina	1
4	Application of a Novel Algorithm for Expanding Newborn Screening for Inherited Metabolic Disorders across Europe 2022 ·International Journal of Neonatal Screening ·Simon Jones, David Cheillan, Anupam Chakrapani, Heather J. Church, Simon Heales, (unknown), (unknown), (unknown), (unknown), Alberto Burlina	16
5	A New Approach to Objectively Evaluate Inherited Metabolic Diseases for Inclusion on Newborn Screening Programmes 2022 ·International Journal of Neonatal Screening ·Alberto Burlina, Simon Jones, Anupam Chakrapani, Heather J. Church, Simon Heales, (unknown), (unknown), (unknown), (unknown), David Cheillan	17
6	Diagnosing Mitochondrial Disorders Remains Challenging in the Omics Era 2021 ·Neurology Genetics ·Patrick Forny, Emma Footitt, James Davison, Amanda Lam, Cathy E. Woodward, Spyros Batzios, Sanjay Bhate, Anupam Chakrapani, Maureen Cleary, Paul Gissen, Stephanie Grünewald, Jane A. Hurst, Richard H. Scott, Simon Heales, Thomas S. Jacques, Thomas Cullup, Shamima Rahman	16
7	Bi-allelic Variants in TKFC Encoding Triokinase/FMN Cyclase Are Associated with Cataracts and Multisystem Disease 2020 ·The American Journal of Human Genetics ·Saskia B. Wortmann, Brigitte Meunier, Lamia Mestek, (unknown), (unknown), Emma Clement, Daniel Weghuber, (unknown), (unknown), F. Taha, Wyatt W. Yue, Simon Heales, James Davison, Johannes A. Mayr, Shamima Rahman	18
8	Cerebral folate deficiency: Analytical tests and differential diagnosis 2019 ·Journal of Inherited Metabolic Disease ·Simon Pope, Rafael Artuch, Simon Heales, Shamima Rahman	53
9	Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial–neuronal interactions 2012 ·Journal of Neurochemistry ·Emma Mead, Angelina J. Mosley, Simon Eaton, (unknown), Simon Heales, Jennifer M. Pocock	69
10	The monoamine neurotransmitter disorders: an expanding range of neurological syndromes 2011 ·The Lancet Neurology ·Manju A. Kurian, Paul Gissen, Martin A. Smith, Simon Heales, Peter T. Clayton	248
11	Pyridoxal 5′‐phosphate deficiency causes a loss of aromatic l‐amino acid decarboxylase in patients and human neuroblastoma cells, implications for aromatic l‐amino acid decarboxylase and vitamin B₆ deficiency states 2010 ·Journal of Neurochemistry ·G Allen, Viruna Neergheen, Marcus Oppenheim, Julia C. Fitzgerald, Emma Footitt, Keith Hyland, Peter T. Clayton, John M. Land, Simon Heales	33
12	Molecular and phenotypic characterization of a mouse model of oculopharyngeal muscular dystrophy reveals severe muscular atrophy restricted to fast glycolytic fibres 2010 ·Human Molecular Genetics ·Capucine Trollet, Seyed Yahya Anvar, Andrea Venema, Iain P. Hargreaves, Keith Foster, Alban Vignaud, Arnaud Ferry, Elisa Négroni, Christophe Hourdé, Martín A. Baraibar, Peter A.C. ’t Hoen, J. Eric Davies, David C. Rubinsztein, Simon Heales, Vincent Mouly, Silvère M. van der Maarel, Gillian Butler‐Browne, Vered Raz, George Dickson	70
13	Differential effects of albumin on microglia and macrophages; implications for neurodegeneration following blood–brain barrier damage 2009 ·Journal of Neurochemistry ·Claudie Hooper, (unknown), (unknown), Ioanna Sevastou, David Baker, Simon Heales, Jennifer M. Pocock	48
14	Mutations in the Gene Encoding 3-Hydroxyisobutyryl-CoA Hydrolase Results in Progressive Infantile Neurodegeneration 2006 ·The American Journal of Human Genetics ·Ference J. Loupatty, Peter T. Clayton, Jos P.N. Ruiter, Rob Ofman, Lodewijk IJlst, Garry K. Brown, David R. Thorburn, Robert A. Harris, Marinus Durán, (unknown), S. Krywawych, Simon Heales, Ronald J. A. Wanders	66
15	The Effect of HMG-CoA Reductase Inhibitors on Coenzyme Q10 2005 ·Drug Safety ·Iain P. Hargreaves, Andrew Duncan, Simon Heales, John M. Land	68
16	Neuroprotective Role of the Reaper-Related Serine Protease HtrA2/Omi Revealed by Targeted Deletion in Mice 2004 ·Molecular and Cellular Biology ·L. Miguel Martins, Alastair Morrison, Kristina Klupsch, Valentina Fedele, Nicoleta Moisoi, Peter Teismann, Alejandro Abuin, Evelyn Grau, Martin Geppert, George P. Livi, Caretha L. Creasy, Alison Martin, Iain P. Hargreaves, Simon Heales, Hitoshi Okada, Sebastian Brandner, Jörg B. Schulz, Tak W. Mak, Julian Downward	315
17	Association between mitochondrial dysfunction and severity and outcome of septic shock breakdown → 2002 ·The Lancet ·David Brealey, M. P. Brand, Iain P. Hargreaves, Simon Heales, John M. Land, Ryszard T. Smoleński, Nathan Davies, Chris E. Cooper, Mervyn Singer	1085
18	Mitochondrial dysfunction in human septic shock 1999 ·UCL Discovery (University College London) ·David Brealey, (unknown), Nathan Davies, Chris E. Cooper, Simon Heales, Jochen Lang, Mervyn Singer	1
19	Peroxynitrite Anion Stimulates Arginine Release from Cultured Rat Astrocytes 1999 ·Journal of Neurochemistry ·(unknown), Ángeles Almeida, Simon Heales, José M. Medina, (unknown)	22
20	Production of Stable Solutions of 7,8-Dihydropterin 1989 ·Pteridines ·Simon Heales, Κ. Hyland	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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