Seigo Izumo

30.3k citations

161 papers · 24.1k indexed · 7 hit papers · h-index 82

Impact in

Cardiology and Cardiovascular Medicine top 0.05%
- Cardiac Fibrosis and Remodeling
- Cardiomyopathy and Myosin Studies
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Renin-Angiotensin System Studies
Molecular Biology top 0.1%
- Congenital heart defects research
- Signaling Pathways in Disease
- Ion channel regulation and function

Papers in

Cardiology and Cardiovascular Medicine 83
- Cardiomyopathy and Myosin Studies 38
- Cardiac Fibrosis and Remodeling 29
- Cardiac electrophysiology and arrhythmias 19
Molecular Biology 132
- Congenital heart defects research 56
- Signaling Pathways in Disease 15
- Developmental Biology and Gene Regulation 13
- Muscle Physiology and Disorders 13
- Ion channel regulation and function 11

Co-authors: Junichi Sadoshima Vijak Mahdavi Peter M. Kang Julie R. McMullen Armin Haunstetter Oleg Tarnavski B Nadal-Ginard Tetsuo Shioi
Journals: Circulation Research (23 papers)Proceedings of the National Academy of Sciences (12 papers)Journal of Biological Chemistry (10 papers)Journal of Clinical Investigation (10 papers)Molecular and Cellular Biology (9 papers)
Partner nations: United States Japan Australia

In The Last Decade

Seigo Izumo

159 papers receiving 23.6k citations

Hit Papers

7 papers align trajectories log scale

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis 2007 · 1.7k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2007 Nature Medicine
1998 Circulation Research
1997 Annual Review of Physiology
1993 The EMBO Journal
1993 Circulation Research
1988 Proceedings of the National Academy of Sciences
1986 Science

Peers

Countries citing papers authored by Seigo Izumo

Since Specialization

Citations

This map shows the geographic impact of Seigo Izumo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Seigo Izumo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Seigo Izumo more than expected).

Fields of papers citing papers by Seigo Izumo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Seigo Izumo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Seigo Izumo. The network helps show where Seigo Izumo may publish in the future.

Co-authors

The 25 scholars most cited alongside Seigo Izumo, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Seigo Izumo Line = papers co-authored together Seigo Izumo links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Reduced Phosphoinositide 3-Kinase (p110α) Activation Increases the Susceptibility to Atrial Fibrillation American Journal Of Pathology ·Lynette Pretorius, Xiao‐Jun Du, Elizabeth A. Woodcock, Helen Kiriazis, Ruby C.Y. Lin, Silvana Marasco, Robert L. Medcalf, Ziqiu Ming, Geoffrey A. Head, Joon Win Tan, Nelly Cemerlang, Junichi Sadoshima, Tetsuo Shioi, Seigo Izumo, Е. В. Лукошкова, Anthony M. Dart, Garry Jennings, Julie R. McMullen	2009	152
2	Lipopolysaccharide-induced myocardial protection against ischaemia/reperfusion injury is mediated through a PI3K/Akt-dependent mechanism Cardiovascular Research ·Tuanzhu Ha, Fang Hua, Xinhua Liu, Jie Ma, Julie R. McMullen, Tetsuo Shioi, Seigo Izumo, Jim Kelley, Xiang Gao, William Browder, David L. Williams, Race L. Kao, Chuanfu Li	2008	150
3	A Conserved Role for Phosphatidylinositol 3-Kinase but Not Akt Signaling in Mitochondrial Adaptations that Accompany Physiological Cardiac Hypertrophy Cell Metabolism ·Brian T. O’Neill, Jaetaek Kim, Adam R. Wende, Heather Theobald, Joseph Tuinei, Jonathan Buchanan, Aili Guo, Vlad G. Zaha, Don Davis, John C. Schell, Sihem Boudina, Benjamin Wayment, Sheldon E. Litwin, Tetsuo Shioi, Seigo Izumo, Morris J. Birnbaum, E. Dale Abel	2007	112
4	Nkx2.5 cell-autonomous gene function is required for the postnatal formation of the peripheral ventricular conduction system Developmental Biology ·Sonia Meysen, Laurine Marger, Kenneth W. Hewett, T. Jarry‐Guichard, Irina Agarkova, J P Chauvin, Jean Claude Perriard, Seigo Izumo, Robert G. Gourdie, Matteo E. Mangoni, Joël Nargeot, Daniel Gros, Lucile Miquerol	2006	61
5	Phenotype-Genotype Association Grid: A Convenient Method for Summarizing Multiple Association Analyses SHILAP Revista de lepidopterología ·Emelia J. Benjamin, Helen Parise, Ramachandran S. Vasan, Seigo Izumo, Martin G. Larson, Daniel Levy, Steven R. DePalma, Christopher J. O’Donnell, Joel N. Hirschhorn	2006	3
6	18 Mechanisms Controlling Heart Growth in Mammals Cold Spring Harbor Monograph Archive ·Julie R. McMullen, Seigo Izumo	2004	3
7	Alterations in apoptosis regulatory factors during hypertrophy and heart failure American Journal of Physiology-Heart and Circulatory Physiology ·Peter Kang, Patrick Yue, Zhilin Liu, Oleg Tarnavski, Natalya D. Bodyak, Seigo Izumo	2004	54
8	Cardiac Conduction and Arrhythmia: Insights from Nkx2.5 Mutations in Mouse and Humans Novartis Foundation symposium ·Patrick Y. Jay, Charles I. Berul, Makoto Tanaka, Masao Ishii, Yoshihisa Kurachi, Seigo Izumo	2003	22
9	A Mouse Model of Congenital Heart Disease: Cardiac Arrhythmias and Atrial Septal Defect Caused by Haploinsufficiency of the Cardiac Transcription Factor Csx/Nkx2.5 Cold Spring Harbor Symposia on Quantitative Biology ·Makoto Tanaka, Charles I. Berul, Masao Ishii, Patrick Y. Jay, Hiroko Wakimoto, Pamela S. Douglas, Naohito Yamasaki, T. Kawamoto, Josef Gehrmann, Colin T. Maguire, Martina Schinke, Christine E. Seidman, J.G. Seidman, Y Kurachi, Seigo Izumo	2002	45
10	Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein Journal of Clinical Investigation ·Hideko Kasahara, Hiroko Wakimoto, Margaret Liu, Colin T. Maguire, Kimber Converso, Tetsuo Shioi, Weei‐Yuarn Huang, Warren J. Manning, David Paul, Joel Lawitts, Charles I. Berul, Seigo Izumo	2001	106
11	Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein Journal of Clinical Investigation ·Hideko Kasahara, Hiroko Wakimoto, Margaret Liu, Colin T. Maguire, Kimber Converso, Tetsuo Shioi, Weei‐Yuarn Huang, Warren J. Manning, David Paul, Joel Lawitts, Charles I. Berul, Seigo Izumo	2001	14
12	COUP-TF1 Antagonizes Nkx2.5-mediated Activation of the Calreticulin Gene during Cardiac Development Journal of Biological Chemistry ·Lei Guo, Jeffrey M. Lynch, Kimitoshi Nakamura, Larry Fliegel, Hideko Kasahara, Seigo Izumo, Issei Komuro, Luis B. Agellon, Marek Michalak	2001	45
13	Characterization of Homo- and Heterodimerization of Cardiac Csx/Nkx2.5 Homeoprotein Journal of Biological Chemistry ·Hideko Kasahara, Anny Usheva, Tomomi Ueyama, Hiroki Aoki, Nobuo Horikoshi, Seigo Izumo	2001	83
14	IS101 Phosphoinositide 3-Kinase Selectively Regulates Cell Size and Specific Gene Expression in the Adult Mouse Heart Japanese Circulation Journal-english Edition ·Tetsuo Shioi, Peter Kang, Pamela S. Douglas, Claudine M. Yballe, Cantley C Lewis, Joel Lawitts, Seigo Izumo	2000	1
15	Cardiac Expression of the Ventricle-Specific Homeobox Gene Irx4 Is Modulated by Nkx2-5 and dHand Developmental Biology ·Benoit G. Bruneau, Zheng‐Zheng Bao, Makoto Tanaka, Jean‐Jacques Schott, Seigo Izumo, Constance L. Cepko, J.G. Seidman, Christine E. Seidman	2000	149
16	Expression of the Nkx3.1 homobox gene during pre and postnatal development Mechanisms of Development ·Makoto Tanaka, Gary E. Lyons, Seigo Izumo	1999	39
17	Molecular cloning of the human HAND2 gene Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ·Mark W. Russell, Paul R. Kemp, Lihong Wang, Lawrence C. Brody, Seigo Izumo	1998	18
18	Myocyte-Specific Enhancer Factor 2 and Thyroid Hormone Receptor Associate and Synergistically Activate the α-Cardiac Myosin Heavy-Chain Gene Molecular and Cellular Biology ·Youngsook Lee, Bernardo Nadal‐Ginard, Vijak Mahdavi, Seigo Izumo	1997	84
19	Expression of dihydropyridine receptor (Ca2+ channel) and calsequestrin genes in the myocardium of patients with end-stage heart failure. Journal of Clinical Investigation ·Toshiyuki Takahashi, Paul D. Allen, Ronald V. Lacro, Andrew R. Marks, A R Dennis, F J Schoen, William Grossman, James D. Marsh, Seigo Izumo	1992	159
20	Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interaction between hemodynamic and thyroid hormone-induced signals. Journal of Clinical Investigation ·Seigo Izumo, Anne‐Marie Lompré, Rumiko Matsuoka, Gideon Koren, K Schwartz, B Nadal-Ginard, Vijak Mahdavi	1987	382

About Seigo Izumo

Seigo Izumo is a scholar working on Cardiology and Cardiovascular Medicine, Molecular Biology, Immunology and Allergy, Genetics and Aging, having authored 161 papers that have together received 24.1k indexed citations. Recurring topics across this work include Congenital heart defects research (56 papers), Cardiomyopathy and Myosin Studies (38 papers), Cardiac Fibrosis and Remodeling (29 papers), Cardiac electrophysiology and arrhythmias (19 papers), Signaling Pathways in Disease (15 papers), Developmental Biology and Gene Regulation (13 papers), Muscle Physiology and Disorders (13 papers) and Ion channel regulation and function (11 papers). The work is most often cited by research in Cardiology and Cardiovascular Medicine (10.4k citations), Molecular Biology (15.6k citations), Aging (263 citations), Cell Biology (2.0k citations) and Immunology and Allergy (634 citations). Seigo Izumo has collaborated with scholars based in United States, Japan and Australia. Frequent co-authors include Junichi Sadoshima, Vijak Mahdavi, Peter M. Kang, Julie R. McMullen, Armin Haunstetter, Oleg Tarnavski, B Nadal-Ginard, Tetsuo Shioi, Bernardo Nadal‐Ginard and Hiroki Aoki. Their work appears in journals such as Circulation Research, Proceedings of the National Academy of Sciences, Journal of Biological Chemistry, Journal of Clinical Investigation and Molecular and Cellular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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