Saadia A. Karim

10.6k total citations · 2 hit papers
34 papers, 3.3k citations indexed

About

Saadia A. Karim is a scholar working on Oncology, Molecular Biology and Cell Biology. According to data from OpenAlex, Saadia A. Karim has authored 34 papers receiving a total of 3.3k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Oncology, 16 papers in Molecular Biology and 7 papers in Cell Biology. Recurrent topics in Saadia A. Karim's work include Pancreatic and Hepatic Oncology Research (12 papers), Cancer Cells and Metastasis (4 papers) and Cancer-related Molecular Pathways (4 papers). Saadia A. Karim is often cited by papers focused on Pancreatic and Hepatic Oncology Research (12 papers), Cancer Cells and Metastasis (4 papers) and Cancer-related Molecular Pathways (4 papers). Saadia A. Karim collaborates with scholars based in United Kingdom, United States and Germany. Saadia A. Karim's co-authors include Jennifer P. Morton, Owen J. Sansom, Brendan Doyle, Armando E. del Río Hernández, Dariusz Lachowski, Paul Timpson, Valerie G. Brunton, Margaret C. Frame, T.R. Jeffry Evans and Patricia Müller and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Saadia A. Karim

33 papers receiving 3.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mutant p53 Drives Invasion by Promoting Integrin Recycling

2009 641 citations Patricia Müller, Patrick T. Caswell et al. Cell profile →
Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells

2017 401 citations Alistair Rice, E Cortés et al. Oncogenesis profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Saadia A. Karim United Kingdom	22	1.8k	1.6k	725	724	369	34	3.3k
Patrick W.B. Derksen Netherlands	36	3.2k 1.8×	2.4k 1.5×	926 1.3×	765 1.1×	459 1.2×	70	4.9k
María Soledad Sosa United States	21	1.4k 0.8×	1.6k 1.0×	908 1.3×	428 0.6×	501 1.4×	32	2.9k
Cédric Gaggioli France	26	2.2k 1.2×	2.0k 1.3×	959 1.3×	1.4k 1.9×	737 2.0×	37	4.4k
Michael W. Pickup United States	22	1.8k 1.0×	1.9k 1.2×	783 1.1×	812 1.1×	929 2.5×	32	4.0k
Fernando Calvo Spain	22	1.8k 1.0×	1.0k 0.6×	467 0.6×	1.1k 1.5×	336 0.9×	42	2.9k
Jiha Kim United States	15	1.6k 0.9×	1.4k 0.9×	850 1.2×	301 0.4×	351 1.0×	35	2.8k
Naira V. Margaryan United States	28	2.1k 1.2×	1.1k 0.7×	720 1.0×	492 0.7×	278 0.8×	57	2.8k
Bas Ponsioen Netherlands	20	2.2k 1.2×	909 0.6×	473 0.7×	584 0.8×	148 0.4×	27	3.3k
Christine E. Eyler United States	21	1.9k 1.1×	1.8k 1.1×	1.4k 1.9×	294 0.4×	490 1.3×	41	3.9k
Hira Lal Goel United States	29	2.4k 1.3×	1.1k 0.7×	855 1.2×	632 0.9×	366 1.0×	54	3.6k

Countries citing papers authored by Saadia A. Karim

Since Specialization

Citations

This map shows the geographic impact of Saadia A. Karim's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Saadia A. Karim with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Saadia A. Karim more than expected).

Fields of papers citing papers by Saadia A. Karim

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Saadia A. Karim. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Saadia A. Karim. The network helps show where Saadia A. Karim may publish in the future.

Co-authorship network of co-authors of Saadia A. Karim

This figure shows the co-authorship network connecting the top 25 collaborators of Saadia A. Karim. A scholar is included among the top collaborators of Saadia A. Karim based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Saadia A. Karim. Saadia A. Karim is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

May, Stephanie, Katrina H. Stevenson, Miryam Müller, et al.. (2025). A precision image-guided model of stereotactic ablative radiotherapy for hepatocellular carcinoma. Disease Models & Mechanisms. 18(5).

Tesson, Mathias, Katrina H. Stevenson, Saadia A. Karim, et al.. (2024). Targeted irradiation in an autochthonous mouse model of pancreatic cancer. Disease Models & Mechanisms. 17(3). 1 indexed citations

Munro, June, Louise Mitchell, Sarah Laing, et al.. (2023). Optimisation of Sample Preparation from Primary Mouse Tissue to Maintain RNA Integrity for Methods Examining Translational Control. Cancers. 15(15). 3985–3985. 2 indexed citations

Graziano, Vincenzo, Andreas Dannhorn, Heather Hulme, et al.. (2023). Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma. Journal for ImmunoTherapy of Cancer. 11(8). e006457–e006457. 10 indexed citations

Nielsen, Sebastian R., Edward R. Horton, René Jackstadt, et al.. (2021). Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade. Nature Communications. 12(1). 3414–3414. 89 indexed citations

Rice, Alistair, E Cortés, Dariusz Lachowski, et al.. (2017). Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells. Oncogenesis. 6(7). e352–e352. 401 indexed citations breakdown →

Driscoll, David R., Saadia A. Karim, Makoto Sano, et al.. (2016). mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer. Cancer Research. 76(23). 6911–6923. 58 indexed citations

Li, Ang, Jennifer P. Morton, Yafeng Ma, et al.. (2014). Fascin Is Regulated by Slug, Promotes Progression of Pancreatic Cancer in Mice, and Is Associated With Patient Outcomes. Gastroenterology. 146(5). 1386–1396.e17. 89 indexed citations

Nobis, Max, Ewan J. McGhee, Jennifer P. Morton, et al.. (2013). Intravital FLIM-FRET Imaging Reveals Dasatinib-Induced Spatial Control of Src in Pancreatic Cancer. Cancer Research. 73(15). 4674–4686. 99 indexed citations

10.

Karim, Saadia A., Hitesh Patel, Neil O. Carragher, et al.. (2013). Dasatinib inhibits mammary tumour development in a genetically engineered mouse model. The Journal of Pathology. 230(4). 430–440. 12 indexed citations

11.

Müller, Patricia, Antonio G. Trinidad, Paul Timpson, et al.. (2012). Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion. Oncogene. 32(10). 1252–1265. 162 indexed citations

12.

Timpson, Paul, Ewan J. McGhee, Jennifer P. Morton, et al.. (2011). Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53. Cancer Research. 71(3). 747–757. 109 indexed citations

13.

McGhee, Ewan J., Jennifer P. Morton, Alex von Kriegsheim, et al.. (2011). FLIM-FRET imaging in vivo reveals 3D-environment spatially regulates RhoGTPase activity during cancer cell invasion. Small GTPases. 2(4). 239–244. 24 indexed citations

14.

Barrie, Jennifer A., Paul Montague, Saadia A. Karim, et al.. (2010). Modulation of rumpshaker phenotype with wild‐type PLP/DM20 suggests several pathogenic mechanisms. Journal of Neuroscience Research. 88(10). 2135–2145. 6 indexed citations

15.

Morton, Jennifer P., Nigel B. Jamieson, Saadia A. Karim, et al.. (2010). LKB1 Haploinsufficiency Cooperates With Kras to Promote Pancreatic Cancer Through Suppression of p21-Dependent Growth Arrest. Gastroenterology. 139(2). 586–597.e6. 126 indexed citations

16.

Morton, Jennifer P., Paul Timpson, Saadia A. Karim, et al.. (2009). Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer. Proceedings of the National Academy of Sciences. 107(1). 246–251. 465 indexed citations

17.

Müller, Patricia, Patrick T. Caswell, Brendan Doyle, et al.. (2009). Mutant p53 Drives Invasion by Promoting Integrin Recycling. Cell. 139(7). 1327–1341. 641 indexed citations breakdown →

18.

McLaughlin, Marκ, Jennifer A. Barrie, Saadia A. Karim, et al.. (2006). Processing of PLP in a model of Pelizaeus‐Merzbacher disease/SPG2 due to the rumpshaker mutation. Glia. 53(7). 715–722. 18 indexed citations

19.

McLaughlin, Marκ, Saadia A. Karim, Paul Montague, et al.. (2006). Genetic Background Influences UPR but not PLP Processing in the rumpshaker Model of PMD/SPG2. Neurochemical Research. 32(2). 167–176. 20 indexed citations

20.

Vouyiouklis, Demetrius A., Thomas Anderson, H. E. King, et al.. (2002). Mapping of the Dysmyelinating Murine Hindshaker Mutation to a 1.2-cM Interval on Chromosome 3. Genomics. 80(2). 126–128. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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