Margaret C. Frame

21.2k total citations · 5 hit papers
174 papers, 16.5k citations indexed

About

Margaret C. Frame is a scholar working on Molecular Biology, Cell Biology and Immunology and Allergy. According to data from OpenAlex, Margaret C. Frame has authored 174 papers receiving a total of 16.5k indexed citations (citations by other indexed papers that have themselves been cited), including 88 papers in Molecular Biology, 85 papers in Cell Biology and 72 papers in Immunology and Allergy. Recurrent topics in Margaret C. Frame's work include Cell Adhesion Molecules Research (72 papers), Cellular Mechanics and Interactions (55 papers) and Hippo pathway signaling and YAP/TAZ (24 papers). Margaret C. Frame is often cited by papers focused on Cell Adhesion Molecules Research (72 papers), Cellular Mechanics and Interactions (55 papers) and Hippo pathway signaling and YAP/TAZ (24 papers). Margaret C. Frame collaborates with scholars based in United Kingdom, United States and Slovakia. Margaret C. Frame's co-authors include Valerie G. Brunton, Neil O. Carragher, Valerie J. Fincham, Egle Avizienyte, Alan Serrels, Duncan J. McGeoch, Gordon W. McLean, Bryan Serrels, Marta Canel and D. McNab and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Margaret C. Frame

171 papers receiving 16.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Complete DNA Sequence of the Long Unique Region in the Genome of Herpes Simplex Virus Type 1

1988 1.4k citations Margaret C. Frame et al. profile →
The role of focal-adhesion kinase in cancer — a new therapeutic opportunity

2005 855 citations Gordon W. McLean, Neil O. Carragher et al. profile →
Src in cancer: deregulation and consequences for cell behaviour

2002 580 citations Margaret C. Frame profile →
E-cadherin–integrin crosstalk in cancer invasion and metastasis

2013 508 citations Marta Canel, Alan Serrels et al. profile →
Targeting FAK in anticancer combination therapies

2021 254 citations John C. Dawson, Alan Serrels et al. profile →

Peers

Countries citing papers authored by Margaret C. Frame

Since Specialization

Citations

This map shows the geographic impact of Margaret C. Frame's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Margaret C. Frame with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Margaret C. Frame more than expected).

Fields of papers citing papers by Margaret C. Frame

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Margaret C. Frame. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Margaret C. Frame. The network helps show where Margaret C. Frame may publish in the future.

Co-authorship network of co-authors of Margaret C. Frame

This figure shows the co-authorship network connecting the top 25 collaborators of Margaret C. Frame. A scholar is included among the top collaborators of Margaret C. Frame based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Margaret C. Frame. Margaret C. Frame is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	FAK modulates glioblastoma stem cell energetics via regulation of glycolysis and glutamine oxidation 2025 ·Disease Models & Mechanisms ·(unknown), John C. Dawson, Virginia Álvarez-García, Morwenna Muir, Roderick N. Carter, Giles E. Hardingham, C J Davies, Robert M. Graham, Alex von Kriegsheim, Jair Mendes Marques, (unknown), Steven M. Pollard, Neil O. Carragher, Valerie G. Brunton, Margaret C. Frame	0
2	Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia 2023 ·Frontiers in Oncology ·(unknown), (unknown), Sara Erridge, Geoff S. Higgins, Joelle P. Straehla, Margaret C. Frame, Tero Aittokallio, Neil O. Carragher, Daniel Ebner	8
3	A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical–Genetic High-Content Phenotypic Screen 2019 ·Molecular Cancer Therapeutics ·John C. Dawson, Bryan Serrels, Adam Byron, Morwenna Muir, (unknown), Amaya García-Muñoz, Alex von Kriegsheim, Daniel Lietha, Neil O. Carragher, Margaret C. Frame	19
4	Adhesion protein networks reveal functions proximal and distal to cell-matrix contacts 2016 ·Current Opinion in Cell Biology ·Adam Byron, Margaret C. Frame	34
5	Intravital FLIM-FRET Imaging Reveals Dasatinib-Induced Spatial Control of Src in Pancreatic Cancer 2013 ·Cancer Research ·Max Nobis, Ewan J. McGhee, Jennifer P. Morton, Juliane P. Schwarz, Saadia A. Karim, Jean A. Quinn, Mike Edward, Andrew D. Campbell, Lynn McGarry, T.R. Jeffry Evans, Valerie G. Brunton, Margaret C. Frame, Neil O. Carragher, Yingxiao Wang, Owen J. Sansom, Paul Timpson, Kurt I. Anderson	99
6	Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53 2011 ·Cancer Research ·Paul Timpson, Ewan J. McGhee, Jennifer P. Morton, Alex von Kriegsheim, Juliane P. Schwarz, Saadia A. Karim, Brendan Doyle, Jean A. Quinn, Neil O. Carragher, Mike Edward, Michael F. Olson, Margaret C. Frame, Valerie G. Brunton, Owen J. Sansom, Kurt I. Anderson	109
7	The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells 2011 ·International Journal of Cancer ·Alan Serrels, Kenneth J. McLeod, Marta Canel, (unknown), Kathryn Graham, Margaret C. Frame, Valerie G. Brunton	47
8	mDia1 Targets v-Src to the Cell Periphery and Facilitates Cell Transformation, Tumorigenesis, and Invasion 2010 ·Molecular and Cellular Biology ·Masahiro Tanji, Toshimasa Ishizaki, Saman Ebrahimi, (unknown), Taiko Sukezane, Tsuyoshi Akagi, Margaret C. Frame, Nobuo Hashimoto, Susumu Miyamoto, Shuh Narumiya	23
9	Quantitative In vivo Imaging of the Effects of Inhibiting Integrin Signaling via Src and FAK on Cancer Cell Movement: Effects on E-cadherin Dynamics 2010 ·Cancer Research ·Marta Canel, Alan Serrels, Derek Miller, Paul Timpson, Bryan Serrels, Margaret C. Frame, Valerie G. Brunton	111
10	Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer 2009 ·Proceedings of the National Academy of Sciences ·Jennifer P. Morton, Paul Timpson, Saadia A. Karim, Rachel A. Ridgway, Dimitris Athineos, Brendan Doyle, Nigel B. Jamieson, Karin A. Oien, Andrew M. Lowy, Valerie G. Brunton, Margaret C. Frame, T.R. Jeffry Evans, Owen J. Sansom	465
11	Real-time Study of E-Cadherin and Membrane Dynamics in Living Animals: Implications for Disease Modeling and Drug Development 2009 ·Cancer Research ·Alan Serrels, Paul Timpson, Marta Canel, Juliane P. Schwarz, Neil O. Carragher, Margaret C. Frame, Valerie G. Brunton, Kurt I. Anderson	58
12	Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex 2007 ·Nature Cell Biology ·Bryan Serrels, Alan Serrels, Valerie G. Brunton, Mark Holt, Gordon W. McLean, Christopher H. Gray, Gareth E. Jones, Margaret C. Frame	211
13	Identification of Src-Specific Phosphorylation Site on Focal Adhesion Kinase: Dissection of the Role of Src SH2 and Catalytic Functions and Their Consequences for Tumor Cell Behavior 2005 ·Cancer Research ·Valerie G. Brunton, Egle Avizienyte, Valerie J. Fincham, Bryan Serrels, Chester A. Metcalf, Tomi K. Sawyer, Margaret C. Frame	180
14	Src-Mediated Phosphorylation of Focal Adhesion Kinase Couples Actin and Adhesion Dynamics to Survival Signaling 2004 ·Molecular and Cellular Biology ·Mike‐Andrew Westhoff, Bryan Serrels, Valerie J. Fincham, Margaret C. Frame, Neil O. Carragher	215
15	Cell adhesion receptors, tyrosine kinases and actin modulators: a complex three-way circuitry 2004 ·Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·Valerie G. Brunton, Iain R. Macpherson, Margaret C. Frame	149
16	Focal adhesion kinase as a potential target in oncology 2003 ·Expert Opinion on Pharmacotherapy ·Gordon W. McLean, Egle Avizienyte, Margaret C. Frame	51
17	A Novel Role for FAK as a Protease-Targeting Adaptor Protein 2003 ·Current Biology ·Neil O. Carragher, Mike‐Andrew Westhoff, Valerie J. Fincham, Michael D. Schaller, Margaret C. Frame	159
18	Src in cancer 2002 ·Biochimica et Biophysica Acta ·Margaret C. Frame	3
19	v-Src-Induced Modulation of the Calpain-Calpastatin Proteolytic System Regulates Transformation 2002 ·Molecular and Cellular Biology ·Neil O. Carragher, Mike‐Andrew Westhoff, (unknown), David A. Potter, Previn Dutt, John S. Elce, Peter A. Greer, Margaret C. Frame	91
20	The Catalytic Activity of the Src Family Kinases Is Required to Disrupt Cadherin-dependent Cell–Cell Contacts 2000 ·Molecular Biology of the Cell ·(unknown), Gordon W. McLean, Anne W. Wyke, Christos Paraskeva, E. Kenneth Parkinson, Margaret C. Frame, Valerie G. Brunton	140

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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