Alan Ashworth

32.0k citations

162 papers · 15.8k indexed · 5 hit papers · h-index 68

Impact in

Cancer Research top 0.1%
- Cancer Genomics and Diagnostics
- Breast Cancer Treatment Studies
Oncology top 0.2%
- Cancer Cells and Metastasis
- Cancer-related Molecular Pathways
- HER2/EGFR in Cancer Research
- PARP inhibition in cancer therapy

Papers in

Genetics 69
- BRCA gene mutations in cancer 33
- Genomic variations and chromosomal abnormalities 17
Cancer Research 34
- Cancer Genomics and Diagnostics 15
- Breast Cancer Treatment Studies 15

Co-authors: Nicholas C. Turner Andrew Tutt Matthew J. Smalley Jorge S. Reis‐Filho Alan Mackay Rachael Natrajan Anthony J. Swerdlow Michael E. Jones
Journals: British Journal of Cancer (11 papers)Breast Cancer Research (9 papers)The Journal of Pathology (9 papers)Current Biology (7 papers)Oncogene (7 papers)
Partner nations: United Kingdom United States Australia

In The Last Decade

Alan Ashworth

158 papers receiving 15.5k citations

Hit Papers

5 papers align trajectories log scale

FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer 2010 · 544 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2010 Cancer Research
2010 Cell stem cell
2004 Nature reviews. Cancer
2003 Nature
1997 Current Biology

Peers

Countries citing papers authored by Alan Ashworth

Since Specialization

Citations

This map shows the geographic impact of Alan Ashworth's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alan Ashworth with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alan Ashworth more than expected).

Fields of papers citing papers by Alan Ashworth

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alan Ashworth. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alan Ashworth. The network helps show where Alan Ashworth may publish in the future.

Co-authors

The 25 scholars most cited alongside Alan Ashworth, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alan Ashworth Line = papers co-authored together Alan Ashworth links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Discovery of a Novel [6–6–5–5–6] Pentacyclic Tetrahydrocyclopentaphthalazinone as a Promising PARP Inhibitor Scaffold ACS Medicinal Chemistry Letters ·Yagmur U. Doruk, Morgan E. Diolaiti, Alan Ashworth, Tanaji T. Talele	2025	1
2	Family history and risk of breast cancer: an analysis accounting for family structure Breast Cancer Research and Treatment ·Hannah R Brewer, Michael E. Jones, Minouk J. Schoemaker, Alan Ashworth, Anthony J. Swerdlow	2017	174
3	Druggable Genetic Dependencies for Molecularly Defined Subgroups of Oesophageal Cancer Identified From High-Throughput Functional Profiling Annals of Oncology ·Irene Chong, David Cunningham, James Campbell, Ilirjana Bajrami, Rachel Brough, Jessica Frankum, Chris Lord, Alan Ashworth	2014	0
4	Genetic Variants at Chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 Influence the Risk of Breast Cancer in Men PLoS Genetics ·Nick Orr, Rosie Cooke, Michael E. Jones, Olivia Fletcher, Frank Dudbridge, Sarah Chilcott-Burns, Katarzyna Tomczyk, Peter Broderick, Richard S. Houlston, Alan Ashworth, Anthony J. Swerdlow	2011	24
5	FGFR Signaling Promotes the Growth of Triple-Negative and Basal-Like Breast Cancer Cell Lines Both In Vitro and In Vivo Clinical Cancer Research ·Rachel Sharpe, Alex Pearson, María Teresa Herrera-Abreu, Damian Johnson, Alan Mackay, Jonathan Welti, Rachael Natrajan, Andrew R. Reynolds, Jorge S. Reis‐Filho, Alan Ashworth, Nicholas C. Turner	2011	144
6	Molecular profiling reveals frequent gain of MYCN and anaplasia‐specific loss of 4q and 14q in wilms tumor Genes Chromosomes and Cancer ·Richard D. Williams, Reem Al‐Saadi, Rachael Natrajan, Alan Mackay, Tasnim Chagtai, Suzanne E. Little, Sandra Hing, Kerry Fenwick, Alan Ashworth, Paul E. Grundy, James R. Anderson, Jeffrey S. Dome, Elizabeth J. Perlman, Chris Jones, Kathy Pritchard‐Jones	2011	38
7	FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer Cancer Research ·Nicholas C. Turner, Alex Pearson, Rachel Sharpe, Maryou Lambros, Felipe C. Geyer, María Ángeles López‐García, Rachael Natrajan, Caterina Marchiò, Elizabeth Iorns, Alan Mackay, Cheryl Gillett, Anita Grigoriadis, Andrew Tutt, Jorge S. Reis‐Filho, Alan Ashworth Hit paper breakdown →	2010	544
8	A Distinct Spectrum of Copy Number Aberrations in Pediatric High-Grade Gliomas Clinical Cancer Research ·Dorine A. Bax, Alan Mackay, Suzanne E. Little, Diana Carvalho, Marta Viana‐Pereira, Narinder Tamber, Anita Grigoriadis, Alan Ashworth, Rui Manuel Reis, David W. Ellison, Safa Al‐Sarraj, Darren Hargrave, Chris Jones	2010	110
9	BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells Cell stem cell ·Gemma Molyneux, Felipe C. Geyer, Fiona‐Ann Magnay, Afshan McCarthy, Howard Kendrick, Rachael Natrajan, Alan Mackay, Anita Grigoriadis, Andrew Tutt, Alan Ashworth, Jorge S. Reis‐Filho, Matthew J. Smalley Hit paper breakdown →	2010	557
10	Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas The Journal of Pathology ·Felipe C. Geyer, Britta Weigelt, Rachael Natrajan, Maryou B. Lambros, Dario de Biase, Radost Vatcheva, Kay Savage, Alan Mackay, Alan Ashworth, Jorge S. Reis‐Filho	2009	155
11	Genome‐wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (c‐Kit, CD117) and oestrogen receptor‐α (ERα) in response to therapeutic radiation The Journal of Pathology ·Charlotte Westbury, Jorge S. Reis‐Filho, Tim Dexter, Betania Mahler‐Araujo, Kerry Fenwick, Marjan Iravani, Anita Grigoriadis, Suzanne Parry, David Robertson, Alan Mackay, Alan Ashworth, John Yarnold, Clare M. Isacke	2009	32
12	Pathobiology Modern Pathology ·Laura Fulford, Joana Reis, A. Mackay, K. Feinwick, Marjan Iravani, Alan Ashworth, Andrew G. Nicholson, Fernando Schmitt, R. H. W. Simpson, Sunil R. Lakhani, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown)	2007	0
13	Nutrition-Friendly Schools Initiative (NFSI) Public Health Nutrition ·AA Jackson, Alan Ashworth	2006	8
14	Stem cells and breast cancer: A field in transit Nature reviews. Cancer ·Matthew J. Smalley, Alan Ashworth	2003	296
15	Retroviral vectors for establishing tetracycline-regulated gene expression in an otherwise recalcitrant cell line BMC Molecular Biology ·Paraic A. Kenny, Tariq Enver, Alan Ashworth	2002	11
16	Functional and molecular characterisation of mammary side population cells Breast Cancer Research ·Azra Alvi, Helen Clayton, Chirag Joshi, Tariq Enver, Alan Ashworth, María dM Vivanco, Trevor Dale, Matthew J. Smalley	2002	238
17	BRCA1 and BRCA2 Current Biology ·David Bertwistle, Alan Ashworth	2000	5
18	Interaction between the Product of the Breast Cancer Susceptibility Gene BRCA2 and DSS1, a Protein Functionally Conserved from Yeast to Mammals Molecular and Cellular Biology ·Nicola J. Marston, William J. Richards, David A. Hughes, David Bertwistle, Christopher J. Marshall, Alan Ashworth	1999	155
19	3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase Current Biology ·Dario R. Alessi, Mária Deák, Antonio Casamayor, F. Barry Caudwell, Nick Morrice, D. Norman, Piers R. J. Gaffney, Colin B. Reese, Colin N. MacDougall, Diane Harbison, Alan Ashworth, Mary Bownes Hit paper breakdown →	1997	606
20	A candidate spermatogenesis gene on the mouse Y chromosome is homologous to ubiquitin-activating enzyme E1 Nature ·Graham F. Kay, Alan Ashworth, Graeme D. Penny, Morag Dunlop, Sally Swift, Neil Brockdorff, Sohaila Rastant	1991	102

About Alan Ashworth

Alan Ashworth is a scholar working on Genetics, Cancer Research, Reproductive Medicine, Oncology and Molecular Biology, having authored 162 papers that have together received 15.8k indexed citations. Recurring topics across this work include BRCA gene mutations in cancer (33 papers), DNA Repair Mechanisms (17 papers), Genomic variations and chromosomal abnormalities (17 papers), Cancer Genomics and Diagnostics (15 papers), Breast Cancer Treatment Studies (15 papers), Genomics and Chromatin Dynamics (14 papers), Cancer Cells and Metastasis (13 papers) and Cancer Risks and Factors (13 papers). The work is most often cited by research in Cancer Research (4.4k citations), Oncology (5.7k citations), Molecular Biology (9.3k citations), Genetics (3.6k citations) and Pathology and Forensic Medicine (1.8k citations). Alan Ashworth has collaborated with scholars based in United Kingdom, United States and Australia. Frequent co-authors include Nicholas C. Turner, Andrew Tutt, Matthew J. Smalley, Jorge S. Reis‐Filho, Alan Mackay, Rachael Natrajan, Anthony J. Swerdlow, Michael E. Jones, Minouk J. Schoemaker and Howard Kendrick. Their work appears in journals such as British Journal of Cancer, Breast Cancer Research, The Journal of Pathology, Current Biology and Oncogene.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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