Laura M. Machesky

21.0k total citations · 4 hit papers
199 papers, 15.9k citations indexed

About

Laura M. Machesky is a scholar working on Cell Biology, Molecular Biology and Immunology and Allergy. According to data from OpenAlex, Laura M. Machesky has authored 199 papers receiving a total of 15.9k indexed citations (citations by other indexed papers that have themselves been cited), including 135 papers in Cell Biology, 74 papers in Molecular Biology and 48 papers in Immunology and Allergy. Recurrent topics in Laura M. Machesky's work include Cellular Mechanics and Interactions (108 papers), Cell Adhesion Molecules Research (48 papers) and Cellular transport and secretion (31 papers). Laura M. Machesky is often cited by papers focused on Cellular Mechanics and Interactions (108 papers), Cell Adhesion Molecules Research (48 papers) and Cellular transport and secretion (31 papers). Laura M. Machesky collaborates with scholars based in United Kingdom, United States and Germany. Laura M. Machesky's co-authors include Robert H. Insall, Robin C. May, Alan Hall, Thomas D. Pollard, Pascal J. Goldschmidt‐Clermont, Vania Braga, Thomas H. Millard, Neil A. Hotchin, John C. Dawson and Stephen J. Sharp and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Laura M. Machesky

197 papers receiving 15.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Scar1 and the related Wiskott–Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex

1998 753 citations Laura M. Machesky, Robert H. Insall Current Biology profile →
The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

1997 650 citations Laura M. Machesky et al. The Journal of Cell Biology profile →
Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex

1999 613 citations Laura M. Machesky et al. Proceedings of the National Academy of Sciences profile →
Phagocytosis and the actin cytoskeleton

2001 568 citations Laura M. Machesky et al. Journal of Cell Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Laura M. Machesky United Kingdom	68	8.8k	7.9k	2.9k	1.8k	1.3k	199	15.9k
Tadaomi Takenawa Japan	72	10.6k 1.2×	11.4k 1.4×	3.2k 1.1×	1.2k 0.7×	1.3k 1.0×	237	19.3k
Frank B. Gertler United States	78	7.9k 0.9×	9.8k 1.2×	2.2k 0.8×	1.8k 1.0×	2.7k 2.0×	163	18.9k
David R. Critchley United Kingdom	72	9.4k 1.1×	7.3k 0.9×	7.1k 2.4×	2.0k 1.1×	1.1k 0.8×	199	16.9k
Alan Rick Horwitz United States	38	6.8k 0.8×	5.5k 0.7×	2.9k 1.0×	909 0.5×	1.1k 0.8×	56	12.3k
Michiyuki Matsuda Japan	67	5.2k 0.6×	11.2k 1.4×	2.1k 0.7×	2.7k 1.5×	2.2k 1.6×	304	18.1k
Anthony Bretscher United States	70	9.1k 1.0×	11.9k 1.5×	2.3k 0.8×	1.2k 0.7×	1.3k 0.9×	148	19.0k
John H. Hartwig United States	87	9.9k 1.1×	9.7k 1.2×	3.6k 1.2×	3.9k 2.2×	1.1k 0.8×	234	24.8k
Tomas Kirchhausen United States	92	12.2k 1.4×	16.2k 2.0×	1.5k 0.5×	3.5k 2.0×	1.1k 0.8×	215	25.4k
J. Victor Small Austria	78	10.0k 1.1×	6.9k 0.9×	2.5k 0.9×	672 0.4×	699 0.5×	171	15.6k
Klemens Rottner Germany	56	6.3k 0.7×	4.3k 0.5×	1.9k 0.7×	871 0.5×	576 0.4×	151	10.2k

Countries citing papers authored by Laura M. Machesky

Since Specialization

Citations

This map shows the geographic impact of Laura M. Machesky's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Laura M. Machesky with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Laura M. Machesky more than expected).

Fields of papers citing papers by Laura M. Machesky

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Laura M. Machesky. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Laura M. Machesky. The network helps show where Laura M. Machesky may publish in the future.

Co-authorship network of co-authors of Laura M. Machesky

This figure shows the co-authorship network connecting the top 25 collaborators of Laura M. Machesky. A scholar is included among the top collaborators of Laura M. Machesky based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Laura M. Machesky. Laura M. Machesky is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Palmulli, Roberta & Laura M. Machesky. (2025). Is macropinocytosis more than just a passive gulp?. Current Opinion in Cell Biology. 94. 102513–102513. 3 indexed citations

Liu, Hengrui, Samir W. Hamaia, Fernando Hernández, et al.. (2025). The voltage-gated sodium channel β3 subunit modulates C6 glioma cell motility independently of channel activity. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1871(6). 167844–167844. 8 indexed citations

Nicolai, Leo, et al.. (2024). Differential Role of the RAC1-Binding Proteins FAM49b (CYRI-B) and CYFIP1 in Platelets. Cells. 13(4). 299–299.

Megaw, Roly, Zhixian Zhang, Fay Newton, et al.. (2024). Ciliary tip actin dynamics regulate photoreceptor outer segment integrity. Nature Communications. 15(1). 4316–4316. 8 indexed citations

Burgess, Selena G., Nikki R. Paul, Mark W. Richards, et al.. (2024). A nanobody inhibitor of Fascin-1 actin-bundling activity and filopodia formation. Open Biology. 14(3). 230376–230376. 3 indexed citations

Juin, Amélie, Heather J. Spence, & Laura M. Machesky. (2024). Dichotomous role of the serine/threonine kinase MAP4K4 in pancreatic ductal adenocarcinoma onset and metastasis through control of AKT and ERK pathways. The Journal of Pathology. 262(4). 454–466. 1 indexed citations

Machesky, Laura M.. (2023). CYRI proteins: controllers of actin dynamics in the cellular ‘eat vs walk’ decision. Biochemical Society Transactions. 51(2). 579–585. 4 indexed citations

Papalazarou, Vassilis, James Drew, Amélie Juin, et al.. (2022). Collagen VI expression is negatively mechanosensitive in pancreatic cancer cells and supports the metastatic niche. Journal of Cell Science. 135(24). 12 indexed citations

Yelland, Tamas, et al.. (2021). CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation. The Journal of Cell Biology. 220(9). 24 indexed citations

10.

Swaminathan, Karthic, Andrew D. Campbell, Vassilis Papalazarou, et al.. (2020). The RAC1 Target NCKAP1 Plays a Crucial Role in the Progression of Braf;Pten-Driven Melanoma in Mice. Journal of Investigative Dermatology. 141(3). 628–637.e15. 12 indexed citations

11.

Papalazarou, Vassilis, Tong Zhang, Nikki R. Paul, et al.. (2020). The creatine–phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis. Nature Metabolism. 2(1). 62–80. 114 indexed citations

12.

Yelland, Tamas, et al.. (2020). Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1. Structure. 29(3). 226–237.e4. 12 indexed citations

13.

Singh, Shashi Prakash, Peter A. Thomason, Sérgio Lilla, et al.. (2020). Cell–substrate adhesion drives Scar/WAVE activation and phosphorylation by a Ste20-family kinase, which controls pseudopod lifetime. PLoS Biology. 18(8). e3000774–e3000774. 17 indexed citations

14.

Volz, Julia, Sarah Beck, Sheila Bryson, et al.. (2019). Platelet lamellipodium formation is not required for thrombus formation and stability. Blood. 134(25). 2318–2329. 33 indexed citations

15.

Maritzen, Tanja, Tobias Zech, Michael Rahbek Schmidt, et al.. (2012). Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex. Proceedings of the National Academy of Sciences. 109(26). 10382–10387. 36 indexed citations

16.

Veltman, Douwe M., Jason King, Laura M. Machesky, & Robert H. Insall. (2012). SCAR knockouts in Dictyostelium : WASP assumes SCAR’s position and upstream regulators in pseudopods. The Journal of Cell Biology. 198(4). 501–508. 69 indexed citations

17.

Yu, Xinzi, Tobias Zech, Laura McDonald, et al.. (2012). N-WASP coordinates the delivery and F-actin–mediated capture of MT1-MMP at invasive pseudopods. The Journal of Cell Biology. 199(3). 527–544. 138 indexed citations

18.

Li, Ang, John C. Dawson, Manuel G. Forero, et al.. (2010). The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion. Current Biology. 20(4). 339–345. 241 indexed citations

19.

Magdalena, Juana, Thomas H. Millard, & Laura M. Machesky. (2003). Microtubule involvement in NIH 3T3 Golgi and MTOC polarity establishment. Journal of Cell Science. 116(4). 743–756. 97 indexed citations

20.

Millard, Tom H. & Laura M. Machesky. (2001). The Wiskott–Aldrich syndrome protein (WASP) family. Trends in Biochemical Sciences. 26(3). 198–199. 20 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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