S. Swaminathan

22.4k citations

54 papers · 16.8k indexed · 2 hit papers · h-index 30

Molecular Biology top 0.2%
Materials Chemistry top 1%
Atomic and Molecular Physics, and Optics top 1%
Spectroscopy top 0.2%
Organic Chemistry top 1%

Co-authors: Martin Karplus Barry D. Olafson Robert E. Bruccoleri David J. States Bernard R. Brooks Philip H. Bolton Norbert Bischofberger Ke Yu Wang
Topics: DNA and Nucleic Acid Chemistry (16 papers)HIV/AIDS drug development and treatment (16 papers)HIV Research and Treatment (12 papers)
Cited by: Molecular Biology Virology Spectroscopy
Journals: Science Proceedings of the National Academy of Sciences Journal of the American Chemical Society
Partner nations: United States France India

In The Last Decade

S. Swaminathan

54 papers receiving 16.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

1983 12.9k citations Barry D. Olafson, S. Swaminathan et al. profile →
Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site: Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity

1997 876 citations Choung U. Kim, Lijun Zhang et al. profile →

Peers

Countries citing papers authored by S. Swaminathan

Since Specialization

Citations

This map shows the geographic impact of S. Swaminathan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by S. Swaminathan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites S. Swaminathan more than expected).

Fields of papers citing papers by S. Swaminathan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by S. Swaminathan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by S. Swaminathan. The network helps show where S. Swaminathan may publish in the future.

Co-authorship network of co-authors of S. Swaminathan

This figure shows the co-authorship network connecting the top 25 collaborators of S. Swaminathan. A scholar is included among the top collaborators of S. Swaminathan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with S. Swaminathan. S. Swaminathan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Structural basis for RNA replication by the hepatitis C virus polymerase 2015 ·Science ·T.C. Appleby,Jason K. Perry,Eisuke Murakami,Ona Barauskas,Joy Y. Feng,Aesop Cho,David Fox,Diana Wetmore,Mary E. McGrath,Adrian S. Ray,Michael J. Sofia,S. Swaminathan,Thomas E. Edwards	254
2	Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350) 2013 ·Bioorganic & Medicinal Chemistry Letters ·Lianhong Xu,(unknown),Allen Y. Hong,(unknown),Bernard P. Murray,Christian Callebaut,(unknown),(unknown),(unknown),Luong Tsai,Kirsten M. Stray,Robert G. Strickley,Jianhong Wang,L. Tong,S. Swaminathan,Gerry Rhodes,Manoj C. Desai	22
3	Visualizing the Molecular Interactions of a Nucleotide Analog, GS-9148, with HIV-1 Reverse Transcriptase–DNA Complex 2010 ·Journal of Molecular Biology ·E.B. Lansdon,Dharmaraj Samuel,Leanna Lagpacan,Katherine M. Brendza,Kirsten White,Magdeleine Hung,Xiaohong Liu,Constantine G. Boojamra,Richard L. Mackman,Tomáš Cihlář,Adrian S. Ray,Mary E. McGrath,S. Swaminathan	37
4	Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs 2007 ·Bioorganic & Medicinal Chemistry ·Richard L. Mackman,Lijun Zhang,(unknown),Constantine G. Boojamra,Janet L. Douglas,Deborah Grant,Hon C. Hui,Choung U. Kim,Geneviève Laflamme,Jay P. Parrish,Antitsa Stoycheva,S. Swaminathan,Keyu Wang,Tomáš Cihlář	24
5	Synthesis And Anti-Hiv Activity Of Cyclic Pyrimidine Phosphonomethoxy Nucleosides And Their Prodrugs: A Comparison Of Phosphonates And Corresponding Nucleosides 2007 ·Nucleosides Nucleotides & Nucleic Acids ·Richard L. Mackman,Lijun Zhang,(unknown),Constantine G. Boojamra,James Chen,Janet L. Douglas,Deborah Grant,Geneviève Laflamme,Hon C. Hui,Choung U. Kim,Jay P. Parrish,Antitsa Stoycheva,S. Swaminathan,Keyu Wang,Tomáš Cihlář	17
6	Suppression of HIV-1 Protease Inhibitor Resistance by Phosphonate-mediated Solvent Anchoring 2006 ·Journal of Molecular Biology ·Tomáš Cihlář,Gong-Xin He,Xiaohong Liu,James Chen,Marcos Hatada,S. Swaminathan,Martin J. McDermott,Zhengyu Yang,Andrew Mulato,Xiaowu Chen,Stephanie A. Leavitt,Kirsten M. Stray,William A. Lee	47
7	A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT 2005 ·AIDS ·Kirsten White,Nicolas Margot,(unknown),James Chen,Adrian S. Ray,(unknown),Ruth Wang,Martin J. McDermott,S. Swaminathan,Michael D. Miller	65
8	Microbial reduction of ?-chloroketone to ?-chlorohydrin 2001 ·Journal of Industrial Microbiology & Biotechnology ·Animesh Goswami,(unknown),Michael J. Totleben,S. Swaminathan,R. N. Patel	11
9	Biexponential Decomposition of a Neuraminidase Inhibitor Prodrug (GS-4104) in Aqueous Solution 1998 ·Pharmaceutical Research ·Reza Oliyai,Lung‐Chi Yuan,(unknown),S. Swaminathan,(unknown),William A. Lee	9
10	Determination of the Number and Location of the Manganese Binding Sites of DNA Quadruplexes in Solution by EPR and NMR in the Presence and Absence of Thrombin 1996 ·Journal of Molecular Biology ·Vasilios M. Marathias,Ke Yu Wang,Surat Kumar,(unknown),S. Swaminathan,Philip H. Bolton	59
11	New Series of Potent, Orally Bioavailable, Non-Peptidic Cyclic Sulfones as HIV-1 Protease Inhibitors 1996 ·Journal of Medicinal Chemistry ·Choung U. Kim,Lawrence R. McGee,Steven H. Krawczyk,(unknown),Yoko Harada,S. Swaminathan,Norbert Bischofberger,Ming S. Chen,Julie M. Cherrington,Shelly Xiong,Linda C. Griffin,Kenneth C. Cundy,Angela Lee,Betty Yu,(unknown),John W. Erickson	56
12	Determination of the number and location of the manganese binding sites of DNA quadruplexes in solution by EPR and NMR 1995 ·Nucleic Acids Research ·Ke Yu Wang,(unknown),S. Swaminathan,Philip H. Bolton	22
13	Tertiary Structure Motif of Oxytricha Telomere DNA 1994 ·Biochemistry ·Ke Yu Wang,S. Swaminathan,Philip H. Bolton	19
14	Deoxyoligonucleotides containing 2′,5′ acetal linkages: Synthesis and hybridization properties 1994 ·Tetrahedron Letters ·(unknown),Xiaodong Cao,S. Swaminathan,Mark D. Matteucci	14
15	The tertiary structure of a DNA aptamer which binds to and inhibits thrombin determines activity 1993 ·Biochemistry ·Ke Yu Wang,Steven H. Krawczyk,Norbert Bischofberger,S. Swaminathan,Philip H. Bolton	146
16	Theoretical Account of the ‘Spine of Hydration’ in the Minor Groove of Duplex d(CGCGAATTCGCG) 1990 ·Journal of Biomolecular Structure and Dynamics ·P.S. Subramanian,S. Swaminathan,D. L. Beveridge	19
17	Conformational and helicoidal analysis of the molecular dynamics of proteins: “Curves,” dials and windows for a 50 psec dynamic trajectory of BPTI 1990 ·Proteins Structure Function and Bioinformatics ·S. Swaminathan,G. Ravishanker,David L. Beveridge,Richard Lavery,(unknown),Heinz Sklenar	22
18	Conformational and Helicoidal Analysis of 30 PS of Molecular Dynamics on the d(CGCGAATTCGCG) Double Helix: “Curves”, Dials and Windows 1989 ·Journal of Biomolecular Structure and Dynamics ·G. Ravishanker,S. Swaminathan,D. L. Beveridge,Richard Lavery,Heinz Sklenar	200
19	Structure and internal mobility of proteins: A molecular dynamics study of hen egg white lysozyme 1986 ·Biopolymers ·Toshiko Ichiye,Barry D. Olafson,S. Swaminathan,Martin Karplus	23
20	Molecular dynamics of myoglobin at 298 degrees K. Results from a 300-ps computer simulation 1985 ·Biophysical Journal ·Ronald M. Levy,Robert P. Sheridan,Joe W. Keepers,(unknown),S. Swaminathan,Martin Karplus	59

About S. Swaminathan

S. Swaminathan is a scholar working on Virology, Infectious Diseases and Spectroscopy, having authored 54 papers that have together received 16.8k indexed citations. Recurring topics across this work include DNA and Nucleic Acid Chemistry (16 papers), HIV/AIDS drug development and treatment (16 papers) and HIV Research and Treatment (12 papers). The work is most often cited by research in Molecular Biology (11.7k citations), Virology (770 citations) and Spectroscopy (1.8k citations). S. Swaminathan has collaborated with scholars based in United States, France and India. Frequent co-authors include Martin Karplus, Barry D. Olafson, Robert E. Bruccoleri, David J. States, Bernard R. Brooks, Philip H. Bolton, Norbert Bischofberger, Ke Yu Wang, Tomáš Cihlář and Matthew A. Williams. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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