Mark D. Matteucci

6.2k citations

66 papers · 5.2k indexed · 2 hit papers · h-index 35

Co-authors: Brian C. Froehler M. H. CARUTHERS John F. Milligan Richard W. Wagner John C. Martin Peter G. Ng Marvin H. Caruthers Arnold J. Gutierrez
Topics: DNA and Nucleic Acid Chemistry (49 papers)Advanced biosensing and bioanalysis techniques (29 papers)RNA Interference and Gene Delivery (18 papers)
Cited by: Molecular Biology Organic Chemistry Cancer Research
Journals: Science Proceedings of the National Academy of Sciences Journal of the American Chemical Society
Partner nations: United States France Hungary

In The Last Decade

Mark D. Matteucci

64 papers receiving 4.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Synthesis of deoxyoligonucleotides on a polymer support

1981 762 citations Mark D. Matteucci et al. profile →
Current concepts in antisense drug design

1993 507 citations John F. Milligan, Mark D. Matteucci et al. Journal of Medicinal Chemistry profile →

Peers

Countries citing papers authored by Mark D. Matteucci

Since Specialization

Citations

This map shows the geographic impact of Mark D. Matteucci's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark D. Matteucci with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark D. Matteucci more than expected).

Fields of papers citing papers by Mark D. Matteucci

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark D. Matteucci. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark D. Matteucci. The network helps show where Mark D. Matteucci may publish in the future.

Co-authorship network of co-authors of Mark D. Matteucci

This figure shows the co-authorship network connecting the top 25 collaborators of Mark D. Matteucci. A scholar is included among the top collaborators of Mark D. Matteucci based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark D. Matteucci. Mark D. Matteucci is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Comparison of hypoxia-activated prodrug evofosfamide (TH-302) and ifosfamide in preclinical non-small cell lung cancer models 2016 ·Cancer Biology & Therapy ·Jessica D. Sun,Qian Liu,Dharmendra Ahluwalia,Damien Ferraro,Yan Wang,Don Jung,Mark D. Matteucci,Charles P. Hart	21
2	Enhancement of hypoxia-activated prodrug TH-302 anti-tumor activity by Chk1 inhibition 2015 ·BMC Cancer ·Fanying Meng,(unknown),Jessica D. Sun,Qian Liu,Dharmendra Ahluwalia,Yan Wang,Mark D. Matteucci,Charles P. Hart	21
3	TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: optimization of dosing regimens and schedules 2012 ·Cancer Chemotherapy and Pharmacology ·Qian Liu,Jessica D. Sun,Jingli Wang,Dharmendra Ahluwalia,Amanda F. Baker,Lee D. Cranmer,Damien Ferraro,Yan Wang,(unknown),W. S. Ammons,John G. Curd,Mark D. Matteucci,Charles P. Hart	86
4	Molecular and Cellular Pharmacology of the Hypoxia-Activated Prodrug TH-302 2011 ·Molecular Cancer Therapeutics ·Fanying Meng,James Evans,(unknown),Monica Banica,Lingyun Lan,Gustavo Lorente,Jianxin Duan,Xiaohong Cai,Alexandra M. Mowday,Christopher P. Guise,Andrej Maroz,Robert F. Anderson,Adam V. Patterson,Gregory C. Stachelek,Peter M. Glazer,Mark D. Matteucci,Charles P. Hart	160
5	Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer 2011 ·Clinical Cancer Research ·Jessica D. Sun,Qian Liu,Jingli Wang,Dharmendra Ahluwalia,Damien Ferraro,Yan Wang,Jianxin Duan,W. S. Ammons,John G. Curd,Mark D. Matteucci,Charles P. Hart	142
6	Synthesis and hybridization property of an oligonucleotide containing a 3′-thioformcetal linked pentathymidylate 1999 ·Bioorganic & Medicinal Chemistry Letters ·Jiancun Zhang,Jared T. Shaw,Mark D. Matteucci	8
7	Cellular penetration and antisense activity by a phenoxazine-substituted heptanucleotide 1999 ·Nature Biotechnology ·W. Michael Flanagan,Richard W. Wagner,(unknown),Kuei‐Ying Lin,Mark D. Matteucci	43
8	Synthesis of a N-acylsulfamide linked dinucleoside and its incorporation into an oligonucleotide 1999 ·Bioorganic & Medicinal Chemistry Letters ·Jiancun Zhang,Mark D. Matteucci	9
9	The synthesis and binding properties of oligonucleotide analogs containing diastereomerically pure conformationally restricted acetal linkages 1997 ·Bioorganic & Medicinal Chemistry Letters ·Jianying Wang,Mark D. Matteucci	12
10	Hybridization properties of oligonucleotides bearing a tricyclic 2′-deoxycytidine analog based on a carbazole ring system 1996 ·Tetrahedron Letters ·Mark D. Matteucci,(unknown)	22
11	Potent and selective inhibition of gene expression by an antisense heptanucleotide 1996 ·Nature Biotechnology ·Richard W. Wagner,Mark D. Matteucci,Deborah Grant,(unknown),Brian C. Froehler	97
12	Site and Mechanism of Antisense Inhibition by C-5 Propyne Oligonucleotides 1995 ·Biochemistry ·Courtney Moulds,(unknown),Brian C. Froehler,Deborah Grant,(unknown),John F. Milligan,Mark D. Matteucci,Richard W. Wagner	77
13	An assessment of the antisense properties of RNase H-competent and steric-blocking oligomers 1995 ·Nucleic Acids Research ·Michele A. Bonham,Stephen Brown,Ann L. Boyd,(unknown),David A. Bruckenstein,Jeffery C. Hanvey,Stephen A. Thomson,Adrian Pipe,(unknown),John Bisi,Brian C. Froehler,Mark D. Matteucci,Richard W. Wagner,Stewart A. Noble,Lee E. Babiss	134
14	A mild method for the syntheses of 3′-thioformacetal dinucleotides: The development of diphenylphosphinate as a glycosyl donor 1995 ·Tetrahedron Letters ·Jiancun Zhang,Mark D. Matteucci	5
15	Development of Antisense Therapeutics: Implications for Cancer Gene Therapy 1994 ·Annals of the New York Academy of Sciences ·John F. Milligan,Robert J. Jones,Brian C. Froehler,Mark D. Matteucci	19
16	Deoxyoligonucleotides containing 2′,5′ acetal linkages: Synthesis and hybridization properties 1994 ·Tetrahedron Letters ·(unknown),Xiaodong Cao,S. Swaminathan,Mark D. Matteucci	14
17	An anti-parallel triple helix motif with oligodeoxynucleotidescontaining 2'-deoxyguanosine and 7-deaza-2'-deoxy xanthosine 1993 ·Nucleic Acids Research ·John F. Milligan,(unknown),Shalini Wadwani,Mark D. Matteucci	89
18	Current concepts in antisense drug designbreakdown → 1993 ·Journal of Medicinal Chemistry ·John F. Milligan,Mark D. Matteucci,John C. Martin	507
19	Oligonucleotide-mediated triple helix formation using an N3-protonated deoxycytidine analog exhibiting pH-independent binding within the physiological range. 1992 ·Proceedings of the National Academy of Sciences ·S. H. KRAWCZYK,John F. Milligan,Shalini Wadwani,Courtney Moulds,Brian C. Froehler,Mark D. Matteucci	73
20	The Use of Nucleoside H-Phosphonates in the Synthesis of Deoxyoligonucleotides 1987 ·Nucleosides and Nucleotides ·Brian C. Froehler,Mark D. Matteucci	13

About Mark D. Matteucci

Mark D. Matteucci is a scholar working on Molecular Biology, Cancer Research and Organic Chemistry, having authored 66 papers that have together received 5.2k indexed citations. Recurring topics across this work include DNA and Nucleic Acid Chemistry (49 papers), Advanced biosensing and bioanalysis techniques (29 papers) and RNA Interference and Gene Delivery (18 papers). The work is most often cited by research in Molecular Biology (4.4k citations), Organic Chemistry (906 citations) and Cancer Research (421 citations). Mark D. Matteucci has collaborated with scholars based in United States, France and Hungary. Frequent co-authors include Brian C. Froehler, M. H. CARUTHERS, John F. Milligan, Richard W. Wagner, John C. Martin, Peter G. Ng, Marvin H. Caruthers, Arnold J. Gutierrez, Kuei‐Ying Lin and Courtney Moulds. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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