Ming S. Chen

2.5k citations

28 papers · 2.2k · 1 hit paper · h-index 18

Impact in

Virology top 2%
- HIV Research and Treatment
Epidemiology top 2%
- Influenza Virus Research Studies
- Respiratory viral infections research
- Cytomegalovirus and herpesvirus research

Papers in

Infectious Diseases 13
- HIV/AIDS drug development and treatment 13
Virology 5
- HIV Research and Treatment 5

Co-authors: Norbert Bischofberger (4 shared papers)Choung U. Kim (4 shared papers)Dirk B. Mendel (4 shared papers)Willard Lew (3 shared papers)Lijun Zhang (3 shared papers)William H. Prusoff (12 shared papers)Matthew A. Williams (2 shared papers)Swami Swaminathan (2 shared papers)
Journals: Journal of Medicinal Chemistry (8 papers)Biochemical Pharmacology (6 papers)Antimicrobial Agents and Chemotherapy (2 papers)Biochemistry (2 papers)Methods in enzymology on CD-ROM/Methods in enzymology (2 papers)
Partner nations: United States Germany United Kingdom

In The Last Decade

Ming S. Chen

28 papers receiving 2.1k citations

Ming S. Chen's Hit Papers

align trajectories log scale

Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site: Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity 1997 · 959 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

1997 Journal of the American Chemical Society

Peers

Countries citing papers authored by Ming S. Chen

Since Specialization

Citations

This map shows the geographic impact of Ming S. Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ming S. Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ming S. Chen more than expected).

Fields of papers citing papers by Ming S. Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ming S. Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ming S. Chen. The network helps show where Ming S. Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside Ming S. Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ming S. Chen Line = papers co-authored together Ming S. Chen links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 28 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site: Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity Journal of the American Chemical Society ·Choung U. Kim, Willard Lew, Matthew A. Williams, Hongtao Liu, Lijun Zhang, Swami Swaminathan, Norbert Bischofberger, Ming S. Chen Hit paper breakdown →	1997	959
2	Oral Administration of a Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071 Protects Mice and Ferrets against Influenza Infection Antimicrobial Agents and Chemotherapy ·Dirk B. Mendel, Chun Y. Tai, Paul A. Escarpe, Weixing Li, Robert W. Sidwell, John H. Huffman, Clive Sweet, K. J. Jakeman	1998	228
3	Identification of GS 4104 as an Orally Bioavailable Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071 Antimicrobial Agents and Chemotherapy ·Weixing Li, Paul A. Escarpe, Eugene J. Eisenberg, Kenneth C. Cundy, Clive Sweet, K. J. Jakeman, James R. Merson, Willard Lew	1998	197
4	Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogs of pyrimidine deoxyribonucleosides against retroviruses Journal of Medicinal Chemistry ·Tai Shun Lin, Ming S. Chen, Colin McLaren, You Song Gao, Ismail Ghazzouli, William H. Prusoff	1987	113
5	Antiviral activity of 2′,3′-dideoxycytidin-2′-ene (2′,3′-dideoxy-2′,3′-didehydrocytidine) against human immunodeficiency virus in vitro Biochemical Pharmacology ·Tai‐Shun Lin, Raymond F. Sohinazi, Ming S. Chen, Elaine Kinney-Thomas, William H. Prusoff	1987	91
6	Kinetic analysis of the interaction of cidofovir diphosphate with human cytomegalovirus DNA polymerase Biochemical Pharmacology ·Xiaofeng Xiong, Jeffrey L. Smith, Choung Kim, Eng‐Shang Huang, Ming S. Chen	1996	71
7	Minor Groove DNA Binders as Antimicrobial Agents. 1. Pyrrole Tetraamides Are Potent Antibacterials against Vancomycin Resistant Enteroccoci and Methicillin Resistant Staphylococcus aureus Journal of Medicinal Chemistry ·Natalia B. Dyatkina, Christopher D. Roberts, Jesse D. Keicher, Yuqin Dai, Joshua P. Nadherny, Wentao Zhang, Uli Schmitz, Ana Kongpachith	2002	63
8	Kinetic analysis of the interaction between the diphosphate of (S)-1-(3-hydroxy-2-phosphonylemthoxypropyl)cytosine, ddCTP, AZTTP, and FIAUTP with human DNA polymerases β and γ Biochemical Pharmacology ·Julie M. Cherrington, S. J. W. Allen, Blaine H. McKee, Ming S. Chen	1994	61
9	New Series of Potent, Orally Bioavailable, Non-Peptidic Cyclic Sulfones as HIV-1 Protease Inhibitors Journal of Medicinal Chemistry ·Choung U. Kim, Lawrence R. McGee, Steven H. Krawczyk, Erik Harwood, Yoko Harada, Swami Swaminathan, Norbert Bischofberger, Ming S. Chen	1996	59
10	Synthesis and biological activities of 5-(hydroxymethyl, azidomethyl, or aminomethyl)-2'-deoxyuridine and related 5'-substituted analogs Journal of Medicinal Chemistry ·George T. Shiau, Raymond F. Schinazi, Ming S. Chen, William H. Prusoff	1980	55
11	Antitumor Agents. 234. Design, Synthesis, and Biological Evaluation of Novel 4β-[(4‘ ‘-Benzamido)-Amino]-4‘-O-Demethyl-Epipodophyllotoxin Derivatives Journal of Medicinal Chemistry ·Zhiyan Xiao, Kenneth F. Bastow, John R. Vance, Robert S. Sidwell, Hui-Kang Wang, Ming S. Chen, Qian Shi, Kuo‐Hsiung Lee	2004	43
12	Inhibition of HIV reverse transcriptase by 2′,3′-dideoxynucleoside triphosphates Biochemical Pharmacology ·Ming S. Chen, Scott C. Oshana	1987	42
13	Selective action of 4'-azidothymidine triphosphate on reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases .alpha. and .beta. Biochemistry ·Ming S. Chen, Rebecca T. Suttmann, Èva Papp, Paul D. Cannon, Mary Jane McRoberts, Chinh Bach, William C. Copeland, Teresa S.‐F. Wang	1993	38
14	Antiviral iodinated pyrimidine deoxyribonucleosides: 5-iodo-2′-deoxyuridine; 5′-iodo-2′-deoxycytidine; 5-iodo-5′-amino-2′,5′-didoxyuridine Pharmacology & Therapeutics ·William H. Prusoff, Ming S. Chen, Tai‐Shun Lin, George T. Shiau, Raymond F. Schinazi, Jamieson Walker +1 other	1979	34
15	The incorporation of 5-iodo-5′-amino-2′,5′-dideoxyuridine and 5-iodo-2′-deoxyuridine into herpes simplex virus DNA. Relationship between antiviral activity and effects on DNA structure Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis ·Ming S. Chen, William H. Prusoff +1 other	1980	33
16	Antiviral and antineoplastic activities of pyrimidine arabinosyl nucleosides and their 5'-amino derivatives Journal of Medicinal Chemistry ·Raymond F. Schinazi, Ming S. Chen, William H. Prusoff	1979	28
17	1-(2-Deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent Journal of Medicinal Chemistry ·Muzammil M. Mansuri, Ismail Ghazzouli, Ming S. Chen, Henry G. Howell, Paul R. Brodfuehrer, Daniel A. Benigni, John C Martin	1987	28
18	[45] Thymidine kinase from Escherichia coli Methods in enzymology on CD-ROM/Methods in enzymology ·Ming S. Chen, William H. Prusoff	1978	18
19	Kinetic and photochemical studies and alteration of ultraviolet sensitivity of Escherichia coli thymidine kinase by halogenated allosteric regulators and substrate analogs Biochemistry ·Ming S. Chen, William H. Prusoff	1977	12
20	In vitro characterization of the anti-human cytomegalovirus activity of PMEA (Adefovir) Antiviral Research ·Xiao‐Feng Xiong, Carmina Flores, Michael D. Fuller, Dirk B. Mendel, Andrew S. Mulato, Keith Moon, Ming S. Chen, Julie M. Cherrington	1997	12

About Ming S. Chen

Ming S. Chen is a scholar working on Infectious Diseases, Virology, Organic Chemistry, Epidemiology and Molecular Biology, having authored 28 papers that have together received 2.2k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (13 papers), Biochemical and Molecular Research (5 papers), HIV Research and Treatment (5 papers), Cytomegalovirus and herpesvirus research (5 papers), DNA and Nucleic Acid Chemistry (5 papers), Herpesvirus Infections and Treatments (4 papers), Influenza Virus Research Studies (3 papers) and Synthesis and Characterization of Heterocyclic Compounds (3 papers). The work is most often cited by research in Virology (234 citations), Epidemiology (1.1k citations), Organic Chemistry (727 citations), Infectious Diseases (453 citations) and Molecular Biology (1.0k citations). Ming S. Chen has collaborated with scholars based in United States, Germany and United Kingdom. Frequent co-authors include Norbert Bischofberger, Choung U. Kim, Dirk B. Mendel, Willard Lew, Lijun Zhang, William H. Prusoff, Matthew A. Williams, Swami Swaminathan, William Graeme Laver and Hongtao Liu. Their work appears in journals such as Journal of Medicinal Chemistry, Biochemical Pharmacology, Antimicrobial Agents and Chemotherapy, Biochemistry and Methods in enzymology on CD-ROM/Methods in enzymology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Ming S. Chen

Impact in

Papers in i

In The Last Decade

Ming S. Chen

Ming S. Chen's Hit Papers

Peers

Countries citing papers authored by Ming S. Chen

Fields of papers citing papers by Ming S. Chen

All Works

About Ming S. Chen

Explore authors with similar magnitude of impact

Papers in