Rick Gussio

4.2k citations

70 papers · 3.6k indexed · h-index 33

Impact in

Toxicology top 1%
Organic Chemistry top 2%
- Synthesis and biological activity

Papers in

Toxicology 4
Neurology 14
- Botulinum Toxin and Related Neurological Disorders 14
- Neurological disorders and treatments 7

Co-authors: Daniel Zaharevitz Conrad Kunick Laurent Meijer Edward A. Sausville James C. Burnett Sina Bavari Christiane Schultz Maryse Leost
Journals: Journal of Medicinal Chemistry (8 papers)Molecular Pharmacology (3 papers)Journal of Biological Chemistry (3 papers)European Journal of Medicinal Chemistry (3 papers)ChemBioChem (3 papers)
Partner nations: United States Germany France

In The Last Decade

Rick Gussio

67 papers receiving 3.5k citations

Peers

Countries citing papers authored by Rick Gussio

Since Specialization

Citations

This map shows the geographic impact of Rick Gussio's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rick Gussio with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rick Gussio more than expected).

Fields of papers citing papers by Rick Gussio

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rick Gussio. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rick Gussio. The network helps show where Rick Gussio may publish in the future.

Co-authors

The 25 scholars most cited alongside Rick Gussio, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Rick Gussio Line = papers co-authored together Rick Gussio links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Specific RITA Modification Produces Hyperselective Cytotoxicity While Maintaining In Vivo Antitumor Efficacy Molecular Cancer Therapeutics ·Brian D. Peyser, Ann Hermone, Joseph M. Salamoun, James C. Burnett, Melinda G. Hollingshead, Connor F. McGrath, Rick Gussio, Peter Wipf	2019	5
2	Modified carbazoles destabilize microtubules and kill glioblastoma multiform cells European Journal of Medicinal Chemistry ·Philippe Diaz, Eric A. Horne, Cong Xu, Ernest Hamel, Michael Wagenbach, Ravil R. Petrov, Weiliang Meng, Brian R. Haas, Parvinder Hothi, Linda Wordeman, Rick Gussio, Nephi Stella	2018	23
3	Evading Pgp Activity in Drug-Resistant Cancer Cells: A Structural and Functional Study of Antitubulin Furan Metotica Compounds Molecular Cancer Therapeutics ·Tam Luong Nguyen, Maria Rosaria, Andrea Pinto, Leonardo Lo Presti, Ernest Hamel, Paola Conti, Rick Gussio, Peter De Wulf	2012	12
4	Interaction of pseudolaric acid B with the colchicine site of tubulin Biochemical Pharmacology ·Taradas Sarkar, Tam Luong Nguyen, SunilJ. Wimalawansa, Jun Hao, Ruoli Bai, Rick Gussio, Samuel X. Qiu, Ernest Hamel	2012	14
5	Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery Stem Cell Research ·Erkan Kiris, Jonathan E. Nuss, James C. Burnett, Krishna P. Kota, 孝志新井, V. Dubenskyy, Vita Kartesiana, Rick Gussio, Lino Tessarollo, Sina Bavari	2011	37
6	Reduced Expression of CD45 Protein-tyrosine Phosphatase Provides Protection against Anthrax Pathogenesis Journal of Biological Chemistry ·Rekha G. Panchal, Ricky L. Ulrich, Steven B. Bradfute, Douglas Lane, Gordon Ruthel, Tara Kenny, Patrick L. Iversen, Arthur O. Anderson, Rick Gussio, William C. Raschke, Sina Bavari	2009	23
7	Evidence for a distinct ligand binding site on tubulin discovered through inhibition by GDP of paclitaxel-induced tubulin assembly in the absence of exogenous GTP Archives of Biochemistry and Biophysics ·Guangfu Zu, Connor F. McGrath, Andrei V. Blokhin, Rick Gussio, Ernest Hamel	2009	0
8	A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has a Very Different Conformation than SNAP-25 Substrate Structure ·Serdar Karabulut, James J. Schmidt, Timothy D. Fenn, James C. Burnett, Demet Araç, Rick Gussio, Robert G. Stafford, 刘续威, Sina Bavari, Axel T. Brünger	2008	49
9	Chemical Genetic Screening Identifies Critical Pathways in Anthrax Lethal Toxin-Induced Pathogenesis Chemistry & Biology ·Rekha G. Panchal, Gordon Ruthel, Katherine C. Brittingham, Douglas Lane, Tara Kenny, Rick Gussio, John S. Lazo, Sina Bavari	2007	10
10	Homology model of RSK2 N-terminal kinase domain, structure-based identification of novel RSK2 inhibitors, and preliminary common pharmacophore Bioorganic & Medicinal Chemistry ·Tam L. Nguyen, Rick Gussio, Jeffrey A. Smith, Deborah A. Lannigan, Sidney M. Hecht, Dominic A. Scudiero, Robert H. Shoemaker, Daniel Zaharevitz	2006	37
11	Comparison of the Activities of the Truncated Halichondrin B Analog NSC 707389 (E7389) with Those of the Parent Compound and a Proposed Binding Site on Tubulin Molecular Pharmacology ·Donnette Dabydeen, James C. Burnett, Ruoli Bai, Pascal Verdier‐Pinard, Sarah J. H. Hickford, George R. Pettit, John W. Blunt, Murray H. G. Munro, Rick Gussio, Ernest Hamel	2006	90
12	Homology Model of the CDK1/cyclin B Complex Journal of Biomolecular Structure and Dynamics ·Connor F. McGrath, Nagarajan Pattabiraman, Glen E. Kellogg, Thomas Lemcke, Conrad Kunick, Edward A. Sausville, Daniel Zaharevitz, Rick Gussio	2005	35
13	Epoxide-containing side chains enhance antiproliferative activity of paullones European Journal of Medicinal Chemistry ·Themistoklis Bilis, Thomas Lemcke, Rick Gussio, Daniel Zaharevitz, Gabriela Fernanda Serrano-Ortega, Laurent Meijer, Conrad Kunick	2005	32
14	Novel small molecule inhibitors of botulinum neurotoxin A metalloprotease activity Biochemical and Biophysical Research Communications ·James C. Burnett, James J. Schmidt, Robert G. Stafford, Rekha G. Panchal, Tam L. Nguyen, Ann Hermone, Jonathan L. Vennerstrom, Connor F. McGrath, Douglas Lane, Edward A. Sausville, Daniel Zaharevitz, Rick Gussio, Sina Bavari	2003	77
15	Identification of a Potent and Selective Pharmacophore for Cdc25 Dual Specificity Phosphatase Inhibitors. Molecular Pharmacology ·John S. Lazo, Kaoru Nemoto, Katharine Pestell, Sigurd D. Petersen, Eileen C. Southwick, Douglas A. Mitchell, William Furey, Rick Gussio, Daniel Zaharevitz, Beomjun Joo, Peter Wipf	2002	162
16	Chemical synthesis and biological properties of pyridine epothilones Chemistry & Biology ·K. C. Nicolaou, Rita Scarpelli, Birgit Bollbuck, Jonathan Carl Zenker, M. Manuela A. Pereira, Markus Wartmann, K.M. REESE, Daniel Zaharevitz, Rick Gussio, P. Giannakakou	2000	125
17	2-Substituted paullones: CDK1/cyclin B-inhibiting property and in vitro antiproliferative activity Bioorganic & Medicinal Chemistry Letters ·Conrad Kunick, Christiane Schultz, Thomas Lemcke, Daniel Zaharevitz, Rick Gussio, А. Н. Канатников, Edward A. Sausville, Maryse Leost, Laurent Meijer	2000	59
18	Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25 European Journal of Biochemistry ·Gabriela Fernanda Serrano-Ortega, Christiane Schultz, Andreas Link, B. Ketzer, Jacek Biernat, Eva‐Maria Mandelkow, James Bibb, Gretchen L. Snyder, Paul Greengard, Daniel Zaharevitz, Rick Gussio, Adrian M. Senderowicz, Edward A. Sausville, Conrad Kunick, Laurent Meijer	2000	328
19	Use of 3D QSAR Methodology for Data Mining the National Cancer Institute Repository of Small Molecules: Application to HIV-1 Reverse Transcriptase Inhibition Methods ·Rick Gussio, Nagarajan Pattabiraman, Glen E. Kellogg, Daniel Zaharevitz	1998	13
20	A pseudoreceptor docking study of 4,5-?-epoxymorphinans with a range of dielectric constants Journal of Computer-Aided Molecular Design ·Rick Gussio, Sovitj Pou, Amman Mujahid, Gary W. Smythers	1992	6

About Rick Gussio

Rick Gussio is a scholar working on Toxicology, Neurology, Cell Biology, Virology and Oncology, having authored 70 papers that have together received 3.6k indexed citations. Recurring topics across this work include Botulinum Toxin and Related Neurological Disorders (14 papers), Microtubule and mitosis dynamics (12 papers), Cancer Treatment and Pharmacology (12 papers), Bacillus and Francisella bacterial research (8 papers), Cancer-related Molecular Pathways (7 papers), Neurological disorders and treatments (7 papers), Cancer therapeutics and mechanisms (6 papers) and Biochemical and Structural Characterization (6 papers). The work is most often cited by research in Toxicology (148 citations), Organic Chemistry (1.1k citations), Cell Biology (641 citations), Oncology (927 citations) and Molecular Biology (1.9k citations). Rick Gussio has collaborated with scholars based in United States, Germany and France. Frequent co-authors include Daniel Zaharevitz, Conrad Kunick, Laurent Meijer, Edward A. Sausville, James C. Burnett, Sina Bavari, Christiane Schultz, Maryse Leost, Ann Hermone and Ernest Hamel. Their work appears in journals such as Journal of Medicinal Chemistry, Molecular Pharmacology, Journal of Biological Chemistry, European Journal of Medicinal Chemistry and ChemBioChem.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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