Conrad Kunick

4.1k citations

107 papers · 3.3k indexed · h-index 30

Impact in

Organic Chemistry top 1%
- Synthesis and Biological Evaluation
- Synthesis and biological activity
Toxicology top 1%

Papers in ⓘ

Organic Chemistry 55
- Synthesis and pharmacology of benzodiazepine derivatives 13
- Synthesis and Biological Evaluation 13
- Chemical synthesis and alkaloids 10
- Synthesis and biological activity 9
Molecular Biology 52

Co-authors: Laurent Meijer (26 shared papers)Daniel Zaharevitz (12 shared papers)Maryse Leost (10 shared papers)Rick Gussio (11 shared papers)Edward A. Sausville (6 shared papers)Andreas Link (13 shared papers)Christiane Schultz (6 shared papers)Thomas Lemcke (14 shared papers)
Journals: Journal of Medicinal Chemistry (10 papers)European Journal of Medicinal Chemistry (8 papers)Archiv der Pharmazie (7 papers)Bioorganic & Medicinal Chemistry Letters (6 papers)Molecules (6 papers)
Partner nations: Germany France United States

In The Last Decade

Conrad Kunick

100 papers receiving 3.2k citations

Peers

Countries citing papers authored by Conrad Kunick

Since Specialization

Citations

This map shows the geographic impact of Conrad Kunick's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Conrad Kunick with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Conrad Kunick more than expected).

Fields of papers citing papers by Conrad Kunick

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Conrad Kunick. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Conrad Kunick. The network helps show where Conrad Kunick may publish in the future.

Co-authors

The 25 scholars most cited alongside Conrad Kunick, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Conrad Kunick Line = papers co-authored together Conrad Kunick links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 107 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25 European Journal of Biochemistry ·Maryse Leost, Christiane Schultz, Andreas Link, Yong‐Zhong Wu, Jacek Biernat, Eva‐Maria Mandelkow, James Bibb, Gretchen L. Snyder, Paul Greengard, Daniel Zaharevitz, Rick Gussio, Adrian M. Senderowicz, Edward A. Sausville, Conrad Kunick, Laurent Meijer	2000	328
2	Paullones, a Series of Cyclin-Dependent Kinase Inhibitors: Synthesis, Evaluation of CDK1/Cyclin B Inhibition, and in Vitro Antitumor Activity Journal of Medicinal Chemistry ·Christiane Schultz, Andreas Link, Maryse Leost, Daniel Zaharevitz, Rick Gussio, Edward A. Sausville, Laurent Meijer, Conrad Kunick	1999	284
3	Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4 Proceedings of the National Academy of Sciences ·Costas A. Lyssiotis, Ruth K. Foreman, Judith Staerk, Michael Garcia, Divya Mathur, Styliani Markoulaki, Jacob H. Hanna, Luke L. Lairson, Bradley D. Charette, Laure C. Bouchez, Michael J. Bollong, Conrad Kunick, Achim Brinker, Charles Y. Cho, Peter G. Schultz, Rudolf Jaenisch	2009	282
4	Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases. PubMed ·Daniel Zaharevitz, Rick Gussio, Maryse Leost, Adrian M. Senderowicz, Tyler Lahusen, Conrad Kunick, Laurent Meijer, Edward A. Sausville	1999	193
5	1-Azakenpaullone is a selective inhibitor of glycogen synthase kinase-3β Bioorganic & Medicinal Chemistry Letters ·Conrad Kunick, Kathrin Lauenroth, Maryse Leost, Laurent Meijer, Thomas Lemcke	2003	147
6	Adenosine Mimetics as Inhibitors of NAD⁺-Dependent Histone Deacetylases, from Kinase to Sirtuin Inhibition Journal of Medicinal Chemistry ·Johannes Trapp, A.M. Jochum, René Meier, Laura R. Saunders, Brett Marshall, Conrad Kunick, Eric Verdin, Peter G. Goekjian, Wolfgang Sippl, Manfred Jung	2006	131
7	Intracellular Targets of Paullones Journal of Biological Chemistry ·Marie Knockaert, Karen Wieking, Sophie Schmitt, Maryse Leost, Karen M. Grant, Jeremy C. Mottram, Conrad Kunick, Laurent Meijer	2002	121
8	Plasmodium falciparum glycogen synthase kinase-3: molecular model, expression, intracellular localisation and selective inhibitors Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics ·Eliane Droucheau, Aline Primot, Virginie Thomas, Denise Mattei, Marie Knockaert, Chris Richardson, Pina Sallicandro, Pietro Alano, Ali Jafarshad, Blandine Baratte, Conrad Kunick, Daniel Parzy, Laurence H. Pearl, Christian Doerig, Laurent Meijer	2003	97
9	Cyclin-Dependent KinasesInitial Approaches to Exploit a Novel Therapeutic Target Pharmacology & Therapeutics ·Edward A. Sausville, Daniel Zaharevitz, Robert Gussio, Laurent Meijer, Maryse Louarn-Leost, Conrad Kunick, Robert Schultz, Tyler Lahusen, Donna Headlee, Sherman F. Stinson	1999	95
10	10-Iodo-11H-indolo[3,2-c]quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A Journal of Medicinal Chemistry ·Hannes Falke, A. Chaikuad, Anja Becker, Nadège Loaëc, Olivier Lozach, Samira Abu Jhaisha, Walter Becker, Peter G. Jones, Lutz Preu, Knut Baumann, Stefan Knapp, Laurent Meijer, Conrad Kunick	2015	89
11	Evaluation and Comparison of 3D-QSAR CoMSIA Models for CDK1, CDK5, and GSK-3 Inhibition by Paullones Journal of Medicinal Chemistry ·Conrad Kunick, Kathrin Lauenroth, Karen Wieking, Xu Xie, Christiane Schultz, Rick Gussio, Daniel Zaharevitz, Maryse Leost, Laurent Meijer, Alexander Weber, Flemming Steen Jørgensen, Thomas Lemcke	2003	86
12	9-Cyano-1-azapaullone (Cazpaullone), a Glycogen Synthase Kinase-3 (GSK-3) Inhibitor Activating Pancreatic β Cell Protection and Replication Journal of Medicinal Chemistry ·Hendrik Stukenbrock, Rainer Mußmann, Marcus Geese, Yoan Ferandin, Olivier Lozach, Thomas Lemcke, Simone Kegel, Alexander Lomow, Ulrike Burk, Cord Dohrmann, Laurent Meijer, Matthias Austen, Conrad Kunick	2008	78
13	Identification of 2-Anilino-9-methoxy-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-ones as Dual PLK1/VEGF-R2 Kinase Inhibitor Chemotypes by Structure-Based Lead Generation Journal of Medicinal Chemistry ·Anne‐Marie Egert‐Schmidt, Jan Dreher, Ute Dunkel, Simone Kohfeld, Lutz Preu, Holger Weber, Jan E. Ehlert, Bettina Mutschler, Frank Totzke, Christoph Schächtele, Michael H.G. Kubbutat, Knut Baumann, Conrad Kunick	2010	60
14	2-Substituted paullones: CDK1/cyclin B-inhibiting property and in vitro antiproliferative activity Bioorganic & Medicinal Chemistry Letters ·Conrad Kunick, Christiane Schultz, Thomas Lemcke, Daniel Zaharevitz, Rick Gussio, Ravi Jalluri, Edward A. Sausville, Maryse Leost, Laurent Meijer	2000	59
15	2-(3-Aryl-3-oxopropen-1-yl)-9-tert-butyl-paullones: A New Antileishmanial Chemotype Journal of Medicinal Chemistry ·Christina Reichwald, Orly Shimony, Ute Dunkel, Nina Sacerdoti‐Sierra, Charles L. Jaffe, Conrad Kunick	2008	57
16	3,6-Diamino-4-(2-halophenyl)-2-benzoylthieno[2,3-b]pyridine-5-carbonitriles Are Selective Inhibitors of Plasmodium falciparum Glycogen Synthase Kinase-3 Journal of Medicinal Chemistry ·Wiebke Fugel, A.E. Oberholzer, Bernhard Gschloessl, Ron Dzikowski, Narkiss Pressburger, Lutz Preu, Laurence H. Pearl, Blandine Baratte, Morgane Ratin, Ilya Okun, Christian Doerig, Sebastian Kruggel, Thomas Lemcke, Laurent Meijer, Conrad Kunick	2012	52
17	Paullones as Inhibitors of Protein Kinases Current Topics in Medicinal Chemistry ·Nadine Tolle, Conrad Kunick	2011	49
18	Alsterpaullone, a novel cyclin‐dependent kinase inhibitor, induces apoptosis by activation of caspase‐9 due to perturbation in mitochondrial membrane potential Molecular Carcinogenesis ·Tyler Lahusen, Adriana De Siervi, Conrad Kunick, Adrian M. Senderowicz	2003	48
19	Inhibitors of the RET tyrosine kinase based on a 2-(alkylsulfanyl)-4-(3-thienyl)nicotinonitrile scaffold European Journal of Medicinal Chemistry ·Wiebke Brandt, Luca Mologni, Lutz Preu, Thomas Lemcke, Carlo Gambacorti‐Passerini, Conrad Kunick	2010	45
20	2-Anilino-4-(benzimidazol-2-yl)pyrimidines – A multikinase inhibitor scaffold with antiproliferative activity toward cancer cell lines European Journal of Medicinal Chemistry ·Renate Determann, Jan Dreher, Knut Baumann, Lutz Preu, Peter G. Jones, Frank Totzke, Christoph Schächtele, Michael H.G. Kubbutat, Conrad Kunick	2012	42

About Conrad Kunick

Conrad Kunick is a scholar working on Organic Chemistry, Molecular Biology, Public Health, Environmental and Occupational Health, Oncology and Pharmacology, having authored 107 papers that have together received 3.3k indexed citations. Recurring topics across this work include Cancer-related Molecular Pathways (13 papers), Synthesis and pharmacology of benzodiazepine derivatives (13 papers), Synthesis and Biological Evaluation (13 papers), Chemical synthesis and alkaloids (10 papers), Research on Leishmaniasis Studies (10 papers), Trypanosoma species research and implications (9 papers), Synthesis and biological activity (9 papers) and Synthesis of Organic Compounds (9 papers). The work is most often cited by research in Organic Chemistry (1.4k citations), Toxicology (154 citations), Molecular Biology (1.8k citations), Geriatrics and Gerontology (81 citations) and Oncology (537 citations). Conrad Kunick has collaborated with scholars based in Germany, France and United States. Frequent co-authors include Laurent Meijer, Daniel Zaharevitz, Maryse Leost, Rick Gussio, Edward A. Sausville, Andreas Link, Christiane Schultz, Thomas Lemcke, Lutz Preu and Adrian M. Senderowicz. Their work appears in journals such as Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry, Archiv der Pharmazie, Bioorganic & Medicinal Chemistry Letters and Molecules.

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