Maryse Leost

3.9k total citations · 2 hit papers
20 papers, 3.3k citations indexed

About

Maryse Leost is a scholar working on Organic Chemistry, Oncology and Molecular Biology. According to data from OpenAlex, Maryse Leost has authored 20 papers receiving a total of 3.3k indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Organic Chemistry, 8 papers in Oncology and 7 papers in Molecular Biology. Recurrent topics in Maryse Leost's work include Cancer-related Molecular Pathways (8 papers), Bioactive Compounds and Antitumor Agents (5 papers) and Quinazolinone synthesis and applications (5 papers). Maryse Leost is often cited by papers focused on Cancer-related Molecular Pathways (8 papers), Bioactive Compounds and Antitumor Agents (5 papers) and Quinazolinone synthesis and applications (5 papers). Maryse Leost collaborates with scholars based in France, United States and Germany. Maryse Leost's co-authors include Laurent Meijer, Conrad Kunick, Daniel Zaharevitz, Rick Gussio, Sophie Leclerc, Jane Endicott, Laurence H. Pearl, Panagiotis Polychronopoulos, Prokopios Magiatis and Paul Greengard and has published in prestigious journals such as Journal of Biological Chemistry, Nature Cell Biology and Journal of Medicinal Chemistry.

In The Last Decade

Maryse Leost

20 papers receiving 3.2k citations

Hit Papers

Indirubin, the active constituent of a Chinese antileukae... 1999 2026 2008 2017 1999 2003 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases
    1999 682 citations Sophie Leclerc, Jane Endicott et al. Nature Cell Biology profile →
  2. GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins
    2003 672 citations Laurent Meijer, Alexios-Leandros Skaltsounis et al. Chemistry & Biology profile →

Peers

Maryse Leost
Conrad Kunick Germany
Sophie Leclerc France
Christoph Schächtele Germany
Atul Purohit United Kingdom
Chuan Shih United States
Robert T. Nolte United States
Yoshitaka Satoh Japan
James M. Trevillyan United States
Frank Totzke Germany
Motonari Uesugi Japan
Conrad Kunick Germany
Maryse Leost
Citations per year, relative to Maryse Leost Maryse Leost (= 1×) peers Conrad Kunick

Countries citing papers authored by Maryse Leost

Since Specialization
Citations

This map shows the geographic impact of Maryse Leost's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Maryse Leost with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Maryse Leost more than expected).

Fields of papers citing papers by Maryse Leost

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Maryse Leost. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Maryse Leost. The network helps show where Maryse Leost may publish in the future.

Co-authorship network of co-authors of Maryse Leost

This figure shows the co-authorship network connecting the top 25 collaborators of Maryse Leost. A scholar is included among the top collaborators of Maryse Leost based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Maryse Leost. Maryse Leost is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Lemcke, Thomas, Rick Gussio, Daniel Zaharevitz, et al.. (2005). Epoxide‐Containing Side Chains Enhance Antiproliferative Activity of Paullones.. ChemInform. 36(46). 1 indexed citations
2.
Gompel, Marie, Maryse Leost, Elisa Bal de Kier Joffé, et al.. (2004). Meridianins, a new family of protein kinase inhibitors isolated from the Ascidian Aplidium meridianum. Bioorganic & Medicinal Chemistry Letters. 14(7). 1703–1707. 175 indexed citations
3.
Schaper, Klaus‐Jürgen, Maryse Leost, Daniel Zaharevitz, et al.. (2004). CDK1‐Inhibitory Activity of Paullones Depends on Electronic Properties of 9‐Substituents. Archiv der Pharmazie. 337(9). 486–492. 24 indexed citations
4.
Kunick, Conrad, et al.. (2004). 1‐Azakenpaullone Is a Selective Inhibitor of Glycogen Synthase Kinase‐3β.. ChemInform. 35(18). 2 indexed citations
5.
Gompel, Marie, et al.. (2004). Meridianins, a New Family of Protein Kinase Inhibitors Isolated from the Ascidian Aplidium meridianum.. ChemInform. 35(34). 2 indexed citations
6.
Polychronopoulos, Panagiotis, Prokopios Magiatis, Alexios‐Léandros Skaltsounis, et al.. (2004). Structural Basis for the Synthesis of Indirubins as Potent and Selective Inhibitors of Glycogen Synthase Kinase-3 and Cyclin-Dependent Kinases. Journal of Medicinal Chemistry. 47(4). 935–946. 326 indexed citations
7.
Kunick, Conrad, et al.. (2003). 1-Azakenpaullone is a selective inhibitor of glycogen synthase kinase-3β. Bioorganic & Medicinal Chemistry Letters. 14(2). 413–416. 147 indexed citations
8.
Meijer, Laurent, Alexios-Leandros Skaltsounis, Prokopios Magiatis, et al.. (2003). GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins. Chemistry & Biology. 10(12). 1255–1266. 672 indexed citations breakdown →
9.
Orhan, İlkay Erdoğan, et al.. (2003). Polyprenyl-hydroquinones and -furans from three marine sponges inhibit the cell cycle regulating phosphatase CDC25A. Natural Product Research. 18(1). 1–9. 39 indexed citations
10.
Knockaert, Marie, et al.. (2002). Synthesis of Paullones with Aminoalkyl Side Chains. Archiv der Pharmazie. 335(7). 311–317. 23 indexed citations
11.
Knockaert, Marie, Sophie Schmitt, Maryse Leost, et al.. (2002). Intracellular Targets of Paullones. Journal of Biological Chemistry. 277(28). 25493–25501. 121 indexed citations
12.
Mettey, Yvette, Marie Gompel, Matthieu Garnier, et al.. (2002). Aloisines, a New Family of CDK/GSK-3 Inhibitors. SAR Study, Crystal Structure in Complex with CDK2, Enzyme Selectivity, and Cellular Effects. Journal of Medicinal Chemistry. 46(2). 222–236. 126 indexed citations
13.
Kunick, Conrad, Christiane Schultz, Thomas Lemcke, et al.. (2000). 2-Substituted paullones: CDK1/cyclin B-inhibiting property and in vitro antiproliferative activity. Bioorganic & Medicinal Chemistry Letters. 10(6). 567–569. 59 indexed citations
14.
Gussio, Rick, Nagarajan Pattabiraman, Glen E. Kellogg, et al.. (2000). Structure-based design modifications of the paullone molecular scaffold for cyclin-dependent kinase inhibition.. PubMed. 15(1). 53–66. 40 indexed citations
15.
Legraverend, Michel, Paul Tunnah, M.E.M. Noble, et al.. (2000). Cyclin-Dependent Kinase Inhibition by New C-2 Alkynylated Purine Derivatives and Molecular Structure of a CDK2−Inhibitor Complex. Journal of Medicinal Chemistry. 43(7). 1282–1292. 75 indexed citations
16.
Leclerc, Sophie, Jane Endicott, Alison M. Lawrie, et al.. (1999). Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases. Nature Cell Biology. 1(1). 60–67. 682 indexed citations breakdown →
17.
Chang, Young‐Tae, Nathanael S. Gray, Gustavo R. Rosania, et al.. (1999). Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors. Chemistry & Biology. 6(6). 361–375. 226 indexed citations
18.
Meijer, Laurent, Sophie Leclerc, & Maryse Leost. (1999). Properties and Potential Applications of Chemical Inhibitors of Cyclin-Dependent Kinases. Pharmacology & Therapeutics. 82(2-3). 279–284. 72 indexed citations
19.
Zaharevitz, Daniel, Rick Gussio, Maryse Leost, et al.. (1999). Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases.. PubMed. 59(11). 2566–9. 193 indexed citations
20.
Schultz, Christiane, Andreas Link, Maryse Leost, et al.. (1999). Paullones, a Series of Cyclin-Dependent Kinase Inhibitors:  Synthesis, Evaluation of CDK1/Cyclin B Inhibition, and in Vitro Antitumor Activity. Journal of Medicinal Chemistry. 42(15). 2909–2919. 284 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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