Tomáš Smutný

910 total citations
33 papers, 710 citations indexed

About

Tomáš Smutný is a scholar working on Pharmacology, Oncology and Molecular Biology. According to data from OpenAlex, Tomáš Smutný has authored 33 papers receiving a total of 710 indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Pharmacology, 12 papers in Oncology and 9 papers in Molecular Biology. Recurrent topics in Tomáš Smutný's work include Pharmacogenetics and Drug Metabolism (21 papers), Drug Transport and Resistance Mechanisms (12 papers) and Hormonal Regulation and Hypertension (7 papers). Tomáš Smutný is often cited by papers focused on Pharmacogenetics and Drug Metabolism (21 papers), Drug Transport and Resistance Mechanisms (12 papers) and Hormonal Regulation and Hypertension (7 papers). Tomáš Smutný collaborates with scholars based in Czechia, Finland and Germany. Tomáš Smutný's co-authors include Petr Pávek, Sridhar Mani, Alejandro Carazo, František Trejtnar, Ján Dušek, Zdeněk Dvořák, Kateřina Vávrová, Alexandr Hrabálek, Věra Klimešová and Jaroslav Roh and has published in prestigious journals such as Biomaterials, International Journal of Molecular Sciences and Journal of Medicinal Chemistry.

In The Last Decade

Tomáš Smutný

32 papers receiving 697 citations

Peers

Countries citing papers authored by Tomáš Smutný

Since Specialization

Citations

This map shows the geographic impact of Tomáš Smutný's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tomáš Smutný with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tomáš Smutný more than expected).

Fields of papers citing papers by Tomáš Smutný

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tomáš Smutný. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tomáš Smutný. The network helps show where Tomáš Smutný may publish in the future.

Co-authorship network of co-authors of Tomáš Smutný

This figure shows the co-authorship network connecting the top 25 collaborators of Tomáš Smutný. A scholar is included among the top collaborators of Tomáš Smutný based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tomáš Smutný. Tomáš Smutný is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Quantifying expression and metabolic activity of genes regulated by pregnane X receptor in primary human hepatocyte spheroids 2025 ·PLoS Computational Biology ·(unknown), (unknown), (unknown), Tomáš Smutný, Jurjen Duintjer Tebbens, Petr Pávek, (unknown)	0
2	LIM and SH3 protein 2 (Lasp2) is a novel pregnane X receptor target gene in mouse liver 2025 ·Molecular Pharmacology ·(unknown), (unknown), Tomáš Smutný, (unknown), (unknown), Matti Ahonen, (unknown), Outi Kummu, Petr Pávek, Jukka Hakkola	1
3	Rifampicin and its derivatives: stability, disposition, and affinity towards pregnane X receptor employing 2D and 3D primary human hepatocytes 2024 ·Biochemical Pharmacology ·Tomáš Smutný, (unknown), (unknown), (unknown), Radim Kučera, Petr Pávek	3
4	Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure 2023 ·Journal of Medicinal Chemistry ·(unknown), Ján Dušek, (unknown), (unknown), (unknown), Karel Chalupský, (unknown), Ivona Pávková, Thales Kronenberger, (unknown), (unknown), (unknown), Tomáš Smutný, Petr Pávek, Radim Nencka	13
5	Gene Expression Profiling of 1α,25(OH)₂D₃ Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic‐Metabolizing Genes 2022 ·Molecular Nutrition & Food Research ·Petr Pávek, Ján Dušek, Tomáš Smutný, (unknown), Radim Kučera, (unknown), (unknown), (unknown), Pavel Souček, Radim Vrzal, Zdeněk Dvořák	2
6	Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids 2021 ·Archives of Toxicology ·Tomáš Smutný, (unknown), (unknown), Jurjen Duintjer Tebbens, Petr Pávek	5
7	3β-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3α-epimer by hepatic metabolism 2020 ·The Journal of Steroid Biochemistry and Molecular Biology ·(unknown), (unknown), (unknown), Ondřej Holas, M Hroch, Tomáš Smutný, (unknown), (unknown), Amit V. Pandey, Stanislav Mičuda, Eva Kudová, Petr Pávek	7
8	Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver 2019 ·International Journal of Molecular Sciences ·(unknown), (unknown), Tomáš Smutný, Petr Pávek, (unknown), Petra Matoušková, Lenka Skálová, Iva Boušová	3
9	Stilbene compound trans-3,4,5,4´-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver 2019 ·Toxicology Letters ·(unknown), (unknown), Ondřej Holas, (unknown), Tomáš Smutný, (unknown), Petra Hirsova, Otto Kučera, Stanislav Mičuda, Albert Braeuning, Petr Pávek	4
10	The 3ʹ-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids 2019 ·Acta Pharmaceutica Sinica B ·Tomáš Smutný, Ján Dušek, (unknown), Jana Nekvindová, (unknown), Stanislav Mičuda, Sabine Gerbal‐Chaloin, Petr Pávek	23
11	Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors 2018 ·Toxicology Letters ·(unknown), (unknown), Ján Dušek, Tomáš Smutný, Alejandro Carazo, (unknown), František Trejtnar, Pavel Bárta, Pavel Anzenbacher, Zdeněk Dvořák, Petr Pávek	37
12	A feasibility study of the toxic responses of human induced pluripotent stem cell-derived hepatocytes to phytochemicals 2018 ·Toxicology in Vitro ·Tomáš Smutný, Riina Harjumäki, Liisa Kanninen, Marjo Yliperttula, Petr Pávek, Yan‐Ru Lou	6
13	Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling 2018 ·Frontiers in Pharmacology ·Alejandro Carazo, Ján Dušek, Ondřej Holas, (unknown), (unknown), Tomáš Smutný, Tomáš Soukup, Martin Doseděl, Petr Pávek	17
14	Iron depletion induces hepatic secretion of biliary lipids and glutathione in rats 2017 ·Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ·(unknown), Jolana Cermanová, M Hroch, Eva Doleželová, (unknown), Tomáš Smutný, Alejandro Carazo, Jaroslav Chládek, Martin Leníček, Petr Nachtigal, Libor Vı́tek, Petr Pávek, Stanislav Mičuda	21
15	Steviol, an aglycone of steviol glycoside sweeteners, interacts with the pregnane X (PXR) and aryl hydrocarbon (AHR) receptors in detoxification regulation 2017 ·Food and Chemical Toxicology ·Ján Dušek, Alejandro Carazo, František Trejtnar, (unknown), Ondřej Holas, Tomáš Smutný, Stanislav Mičuda, Petr Pávek	16
16	Laminin-511 and laminin-521-based matrices for efficient hepatic specification of human pluripotent stem cells 2016 ·Biomaterials ·Liisa Kanninen, Riina Harjumäki, (unknown), (unknown), (unknown), Pauliina Porola, (unknown), Tomáš Smutný, Arto Urtti, Marjo Yliperttula, Yan‐Ru Lou	55
17	1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria 2014 ·European Journal of Medicinal Chemistry ·Galina Karabanovich, Jaroslav Roh, Tomáš Smutný, Jan Němeček, (unknown), Jiřina Stolaříková, Marcela Vejsová, (unknown), Kateřina Vávrová, Petr Pávek, Věra Klimešová, Alexandr Hrabálek	46
18	Resveratrol as an Inhibitor of Pregnane X Receptor (PXR): Another Lesson in PXR Antagonism 2014 ·Journal of Pharmacological Sciences ·Tomáš Smutný, Petr Pávek	11
19	Nuclear receptors in regulation of biotransformation enzymes and drug transporters in the placental barrier 2013 ·Drug Metabolism Reviews ·Petr Pávek, Tomáš Smutný	29
20	Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4α upregulation in primary human hepatocytes 2013 ·Pharmacological Reports ·(unknown), Lucie Krausová, Tomáš Smutný, Radim Vrzal, Zdeněk Dvořák, Ramiro Jover, Petr Pávek	25

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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