Nigel A. Swain

2.1k citations

24 papers · 1.3k indexed · 1 hit paper · h-index 15

Molecular Biology top 10%
Cellular and Molecular Neuroscience top 5%
Organic Chemistry top 10%
Physiology
Cardiology and Cardiovascular Medicine

Co-authors: Richard Storer Sharan K. Bagal Christopher G. Tate Miles Congreve Chris de Graaf Brian E. Marron Richard C. D. Brown Robert M. Owen
Topics: Neuroscience and Neuropharmacology Research (5 papers)Ion channel regulation and function (5 papers)Receptor Mechanisms and Signaling (4 papers)
Cited by: Cellular and Molecular Neuroscience Sensory Systems Molecular Biology
Journals: Cell Proceedings of the National Academy of Sciences Nature Communications
Partner nations: United Kingdom United States China

In The Last Decade

Nigel A. Swain

24 papers receiving 1.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Impact of GPCR Structures on Drug Discovery

2020 245 citations Miles Congreve, Chris de Graaf et al. Cell profile →

Peers

Countries citing papers authored by Nigel A. Swain

Since Specialization

Citations

This map shows the geographic impact of Nigel A. Swain's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nigel A. Swain with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nigel A. Swain more than expected).

Fields of papers citing papers by Nigel A. Swain

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nigel A. Swain. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nigel A. Swain. The network helps show where Nigel A. Swain may publish in the future.

Co-authorship network of co-authors of Nigel A. Swain

This figure shows the co-authorship network connecting the top 25 collaborators of Nigel A. Swain. A scholar is included among the top collaborators of Nigel A. Swain based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nigel A. Swain. Nigel A. Swain is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Identification of nanomolar adenosine A2A receptor ligands using reinforcement learning and structure-based drug design 2025 ·Nature Communications ·Morgan Thomas,Pierre Matricon,(unknown),(unknown),(unknown),Jonathan S. Mason,Jason Brown,(unknown),(unknown),Nigel A. Swain,(unknown),Noel M. O’Boyle,Francesca Deflorian,Andreas Bender,Chris de Graaf	2
2	Delineating the Ligand–Receptor Interactions That Lead to Biased Signaling at the μ-Opioid Receptor 2021 ·Journal of Chemical Information and Modeling ·Brendan Kelly,Scott A. Hollingsworth,David C. Blakemore,Robert M. Owen,Richard Storer,Nigel A. Swain,Deniz Aydın,Rubben Torella,Joseph S. Warmus,Ron O. Dror	18
3	Impact of GPCR Structures on Drug Discoverybreakdown → 2020 ·Cell ·Miles Congreve,Chris de Graaf,Nigel A. Swain,Christopher G. Tate	245
4	The discovery of a potent Na_v1.3 inhibitor with good oral pharmacokinetics 2017 ·MedChemComm ·David C. Pryde,Nigel A. Swain,Paul A. Stupple,Christopher W. West,Brian E. Marron,Christopher J. Markworth,David Printzenhoff,Zhiwu Lin,Peter J. Cox,Rie Suzuki,(unknown),(unknown),(unknown),Joseph S. Warmus,Mark L. Chapman	6
5	Discovery of a Series of Indazole TRPA1 Antagonists 2017 ·ACS Medicinal Chemistry Letters ·David C. Pryde,Brian E. Marron,Christopher W. West,(unknown),George Amato,(unknown),Brett M. Antonio,Karen Padilla,(unknown),(unknown),Joseph S. Warmus,Nigel A. Swain,Kiyoyuki Omoto,John H. Mahoney,Aaron C. Gerlach	19
6	The discovery of a potent series of carboxamide TRPA1 antagonists 2016 ·MedChemComm ·David C. Pryde,Brian E. Marron,(unknown),(unknown),George Amato,(unknown),Karen Padilla,(unknown),Nigel A. Swain,(unknown),S. Skerratt,Thomas Ryckmans,David C. Blakemore,Joseph S. Warmus,Aaron C. Gerlach	9
7	Voltage gated sodium channels as drug discovery targets 2015 ·Channels ·Sharan K. Bagal,Brian E. Marron,Robert M. Owen,Richard Storer,Nigel A. Swain	100
8	Recent progress in sodium channel modulators for pain 2014 ·Bioorganic & Medicinal Chemistry Letters ·Sharan K. Bagal,Mark L. Chapman,Brian E. Marron,(unknown),Richard Storer,Nigel A. Swain	124
9	Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels 2013 ·Proceedings of the National Academy of Sciences ·Ken McCormack,(unknown),Mark L. Chapman,Douglas S. Krafte,Brian E. Marron,Christopher W. West,Michael J. Krambis,Brett M. Antonio,(unknown),David Printzenhoff,Karen Padilla,Zhixin Lin,P. Kay Wagoner,Nigel A. Swain,Paul A. Stupple,Marcel de Groot,Richard P. Butt,Neil A. Castle	174
10	An Ammonia‐Triggered Stereocontrolled Conversion of a γ‐Lactone to the Central Tetrahydropyran of Pederin, Psymberin, and Onnamides D–F 2012 ·European Journal of Organic Chemistry ·(unknown),Nigel A. Swain,(unknown),Théo P. Gonçalves,(unknown)	12
11	Synthesis of novel histamine H4 receptor antagonists 2011 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Duncan A. Hay,Charles E. Mowbray,Michael Paradowski,Matthew D. Selby,Nigel A. Swain,D. H. Williams	14
12	Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: A novel histamine H4 receptor antagonist 2011 ·Bioorganic & Medicinal Chemistry Letters ·Charles E. Mowbray,Andrew Bell,(unknown),Michelle A. Collins,Rhys Jones,(unknown),(unknown),(unknown),Michael Paradowski,Emanuel Schenck,(unknown),Nigel A. Swain,D. H. Williams	29
13	A novel three-step synthesis of Celecoxib via palladium-catalyzed direct arylation 2011 ·Tetrahedron Letters ·(unknown),(unknown),Nigel A. Swain	40
14	Novel Indazole Non-Nucleoside Reverse Transcriptase Inhibitors Using Molecular Hybridization Based on Crystallographic Overlays 2009 ·Journal of Medicinal Chemistry ·Lyn H. Jones,(unknown),(unknown),Catherine Burt,Romuald Corbau,(unknown),Thorsten Knöchel,(unknown),Donald S. Middleton,Charles E. Mowbray,Manos Perros,(unknown),Nigel A. Swain,Robert O. Webster,Mike Westby,Chris Phillips	43
15	Intramolecular C–H insertions adjacent to sulfur for the diastereoselective synthesis of thienofuranones 2004 ·Chemical Communications ·(unknown),Nigel A. Swain,(unknown),(unknown),Gordon Bruton,Richard C. D. Brown	11
16	Synthesis of Furofuran Lignans 2004 ·Synthesis ·Richard C. D. Brown,Nigel A. Swain	23
17	A Versatile Stereoselective Synthesis of endo,exo‐Furofuranones: Application to the Enantioselective Synthesis of Furofuran Lignans. 2004 ·ChemInform ·Nigel A. Swain,Richard C. D. Brown,Gordon Bruton	1
18	An efficient synthesis of endo,exo-furofuranone derivatives 2002 ·Chemical Communications ·Nigel A. Swain,Richard C. D. Brown,Gordon Bruton	14
19	C−H Insertion Approach to the Synthesis of endo,exo-Furofuranones: Synthesis of (±)-Asarinin, (±)-Epimagnolin A, and (±)-Fargesin 2001 ·The Journal of Organic Chemistry ·Richard C. D. Brown,Carole J. R. Bataille,Gordon Bruton,(unknown),Nigel A. Swain	53
20	Mutagenic evaluation of morphine sulphate and pethidine hydrochloride in mice by the micronucleus test. 1982 ·PubMed ·(unknown),Nigel A. Swain	11

About Nigel A. Swain

Nigel A. Swain is a scholar working on Toxicology, Cellular and Molecular Neuroscience and Biochemistry, having authored 24 papers that have together received 1.3k indexed citations. Recurring topics across this work include Neuroscience and Neuropharmacology Research (5 papers), Ion channel regulation and function (5 papers) and Receptor Mechanisms and Signaling (4 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (342 citations), Sensory Systems (73 citations) and Molecular Biology (857 citations). Nigel A. Swain has collaborated with scholars based in United Kingdom, United States and China. Frequent co-authors include Richard Storer, Sharan K. Bagal, Christopher G. Tate, Miles Congreve, Chris de Graaf, Brian E. Marron, Richard C. D. Brown, Robert M. Owen, Gordon Bruton and Mark L. Chapman. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact