Francesca Deflorian

2.2k total citations
42 papers, 1.8k citations indexed

About

Francesca Deflorian is a scholar working on Molecular Biology, Physiology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Francesca Deflorian has authored 42 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 37 papers in Molecular Biology, 22 papers in Physiology and 16 papers in Cellular and Molecular Neuroscience. Recurrent topics in Francesca Deflorian's work include Receptor Mechanisms and Signaling (31 papers), Adenosine and Purinergic Signaling (22 papers) and Neuropeptides and Animal Physiology (15 papers). Francesca Deflorian is often cited by papers focused on Receptor Mechanisms and Signaling (31 papers), Adenosine and Purinergic Signaling (22 papers) and Neuropeptides and Animal Physiology (15 papers). Francesca Deflorian collaborates with scholars based in United States, Italy and United Kingdom. Francesca Deflorian's co-authors include Kenneth A. Jacobson, Stefano Moro, Fiona H. Marshall, Jonathan S. Mason, Roger Cooke, Zhan‐Guo Gao, A.S. Dore, James C. Errey, Giampiero Spalluto and Andrea Bortolato and has published in prestigious journals such as Nature, Angewandte Chemie International Edition and Nature Communications.

In The Last Decade

Francesca Deflorian

41 papers receiving 1.7k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Francesca Deflorian United States 24 1.3k 641 449 373 299 42 1.8k
Silvia Paoletta United States 23 1.1k 0.8× 775 1.2× 440 1.0× 357 1.0× 131 0.4× 42 1.6k
Jonathan S. Mason United States 21 1.7k 1.3× 283 0.4× 754 1.7× 178 0.5× 494 1.7× 29 1.9k
Antonella Ciancetta Italy 22 896 0.7× 471 0.7× 214 0.5× 344 0.9× 206 0.7× 61 1.4k
Stephen P. Andrews United Kingdom 18 1.0k 0.8× 203 0.3× 402 0.9× 364 1.0× 195 0.7× 27 1.4k
N.J. Robertson United Kingdom 16 1.4k 1.1× 393 0.6× 628 1.4× 121 0.3× 183 0.6× 29 1.8k
Margot W. Beukers Netherlands 27 1.0k 0.8× 849 1.3× 418 0.9× 410 1.1× 87 0.3× 42 1.9k
Gina H. Lu United States 21 1.1k 0.9× 594 0.9× 388 0.9× 460 1.2× 105 0.4× 32 2.0k
David M. Thal Australia 22 2.2k 1.7× 243 0.4× 1.1k 2.5× 99 0.3× 250 0.8× 41 2.5k
Céline Valant Australia 29 3.0k 2.3× 282 0.4× 1.9k 4.2× 220 0.6× 521 1.7× 70 3.4k
Paul Jackson United States 22 809 0.6× 142 0.2× 509 1.1× 407 1.1× 51 0.2× 43 1.7k

Countries citing papers authored by Francesca Deflorian

Since Specialization
Citations

This map shows the geographic impact of Francesca Deflorian's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Francesca Deflorian with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Francesca Deflorian more than expected).

Fields of papers citing papers by Francesca Deflorian

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Francesca Deflorian. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Francesca Deflorian. The network helps show where Francesca Deflorian may publish in the future.

Co-authorship network of co-authors of Francesca Deflorian

This figure shows the co-authorship network connecting the top 25 collaborators of Francesca Deflorian. A scholar is included among the top collaborators of Francesca Deflorian based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Francesca Deflorian. Francesca Deflorian is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Thomas, Morgan, Pierre Matricon, Jonathan S. Mason, et al.. (2025). Identification of nanomolar adenosine A2A receptor ligands using reinforcement learning and structure-based drug design. Nature Communications. 16(1). 5485–5485. 2 indexed citations
2.
Deflorian, Francesca, Chris de Graaf, Martyna Szpakowska, et al.. (2025). Design, Synthesis and Pharmacological Characterization of the First Photoswitchable Small-Molecule Agonist for the Atypical Chemokine Receptor 3. ACS Omega. 10(8). 8675–8686.
3.
Southall, Stacey M., Joydeep Banerjee, Jason Brown, et al.. (2022). Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode. ACS Medicinal Chemistry Letters. 13(11). 1776–1782. 1 indexed citations
4.
Deganutti, Giuseppe, Andrei Zhukov, Francesca Deflorian, et al.. (2017). Impact of protein–ligand solvation and desolvation on transition state thermodynamic properties of adenosine A2A ligand binding kinetics. In Silico Pharmacology. 5(1). 16–16. 14 indexed citations
5.
Cheng, R.K., Elena Segala, N.J. Robertson, et al.. (2017). Structures of Human A 1 and A 2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity. Structure. 25(8). 1275–1285.e4. 168 indexed citations
6.
Oswald, Christine, Mathieu Rappas, James Kean, et al.. (2016). Intracellular allosteric antagonism of the CCR9 receptor. Nature. 540(7633). 462–465. 196 indexed citations
7.
Jacobson, Kenneth A., Stefano Costanzi, & Francesca Deflorian. (2013). Probing GPCR Structure. Methods in enzymology on CD-ROM/Methods in enzymology. 520. 199–217. 6 indexed citations
8.
Högberg, Carl, Olof Gidlöf, Francesca Deflorian, et al.. (2012). Farnesyl pyrophosphate is an endogenous antagonist to ADP-stimulated P2Y12 receptor-mediated platelet aggregation. Thrombosis and Haemostasis. 108(7). 119–132. 10 indexed citations
9.
Jacobson, Kenneth A., Рамачандран Баласубраманиан, Francesca Deflorian, & Zhan‐Guo Gao. (2012). G protein-coupled adenosine (P1) and P2Y receptors: ligand design and receptor interactions. Purinergic Signalling. 8(3). 419–436. 72 indexed citations
10.
Deflorian, Francesca & Kenneth A. Jacobson. (2011). Comparison of three GPCR structural templates for modeling of the P2Y12 nucleotide receptor. Journal of Computer-Aided Molecular Design. 25(4). 329–338. 30 indexed citations
11.
Jacobson, Kenneth A., et al.. (2011). Pharmacochemistry of the platelet purinergic receptors. Purinergic Signalling. 7(3). 305–324. 37 indexed citations
12.
Shinkre, Bidhan A., T. Santhosh Kumar, Zhan‐Guo Gao, et al.. (2010). Synthesis and evaluation of 1,2,4-triazolo[1,5-c]pyrimidine derivatives as A2A receptor-selective antagonists. Bioorganic & Medicinal Chemistry Letters. 20(19). 5690–5694. 21 indexed citations
13.
Kumar, T. Santhosh, Francesca Deflorian, Lena S. Yoo, et al.. (2010). Molecular probes for the A2A adenosine receptor based on a pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine scaffold. Bioorganic & Medicinal Chemistry Letters. 21(9). 2740–2745. 21 indexed citations
14.
Rosemond, Erica, Joel Karpiak, Francesca Deflorian, et al.. (2009). Structural basis of the selectivity of the β2-adrenergic receptor for fluorinated catecholamines. Bioorganic & Medicinal Chemistry. 17(23). 7987–7992. 15 indexed citations
15.
Deflorian, Francesca, Stanislav Engel, Anny‐Odile Colson, et al.. (2007). Understanding the structural and functional differences between mouse thyrotropin‐releasing hormone receptors 1 and 2. Proteins Structure Function and Bioinformatics. 71(2). 783–794. 16 indexed citations
16.
Moro, Stefano, Magdalena Bacilieri, & Francesca Deflorian. (2007). Combining ligand-based and structure-based drug design in the virtual screening arena. Expert Opinion on Drug Discovery. 2(1). 37–49. 18 indexed citations
17.
Moro, Stefano, Francesca Deflorian, Magdalena Bacilieri, & Giampiero Spalluto. (2006). Novel Strategies for the Design of New Potent and Selective Human A3 Receptor Antagonists: An Update. Current Medicinal Chemistry. 13(6). 639–645. 25 indexed citations
18.
Cacciari, Barbara, Giampiero Spalluto, Karl‐Norbert Klotz, et al.. (2006). Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: A complete structure–activity profile. Purinergic Signalling. 3(3). 183–193. 14 indexed citations
19.
Varano, Flavia, Daniela Catarzi, Vittoria Colotta, et al.. (2005). 1-Substituted pyrazolo[1,5-c]quinazolines as novel Gly/NMDA receptor antagonists: Synthesis, biological evaluation, and molecular modeling study. Bioorganic & Medicinal Chemistry. 13(19). 5536–5549. 62 indexed citations
20.
Moro, Stefano, Francesca Deflorian, Giampiero Spalluto, et al.. (2003). Demystifying the three dimensional structure of G protein-coupled receptors (GPCRs) with the aid of molecular modeling. Chemical Communications. 2949–2949. 38 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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