Graeme Semple

2.8k total citations
65 papers, 1.9k citations indexed

About

Graeme Semple is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Organic Chemistry. According to data from OpenAlex, Graeme Semple has authored 65 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 37 papers in Molecular Biology, 23 papers in Cellular and Molecular Neuroscience and 13 papers in Organic Chemistry. Recurrent topics in Graeme Semple's work include Receptor Mechanisms and Signaling (24 papers), Neuropeptides and Animal Physiology (16 papers) and Neurotransmitter Receptor Influence on Behavior (7 papers). Graeme Semple is often cited by papers focused on Receptor Mechanisms and Signaling (24 papers), Neuropeptides and Animal Physiology (16 papers) and Neurotransmitter Receptor Influence on Behavior (7 papers). Graeme Semple collaborates with scholars based in United States, United Kingdom and Japan. Graeme Semple's co-authors include David J. Unett, Jeremy G. Richman, Robert M. Jones, Alan Wise, Timothy W. Lovenberg, Steven L. Colletti, Stefan Offermanns, Adriaan P. IJzerman, James Leonard and Zhi‐Liang Chu and has published in prestigious journals such as Journal of Biological Chemistry, Gastroenterology and Pharmacological Reviews.

In The Last Decade

Graeme Semple

65 papers receiving 1.8k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Graeme Semple United States	25	989	468	401	398	386	65	1.9k
Kang Cheng United States	26	881 0.9×	322 0.7×	345 0.9×	119 0.3×	428 1.1×	70	1.9k
Elisabeth Christiansen Denmark	21	1.0k 1.0×	533 1.1×	512 1.3×	320 0.8×	153 0.4×	28	1.6k
Claus T. Christoffersen Denmark	20	884 0.9×	367 0.8×	143 0.4×	175 0.4×	230 0.6×	47	1.8k
Wanda Chan United States	27	743 0.8×	944 2.0×	213 0.5×	196 0.5×	533 1.4×	63	2.4k
Hiroyuki Odaka Japan	26	888 0.9×	822 1.8×	607 1.5×	90 0.2×	202 0.5×	45	2.3k
Marya Liimatta United States	19	852 0.9×	252 0.5×	364 0.9×	296 0.7×	200 0.5×	23	2.0k
Judith L. Treadway United States	32	1.7k 1.7×	709 1.5×	704 1.8×	171 0.4×	551 1.4×	63	2.8k
J Saye United States	14	1.1k 1.2×	797 1.7×	161 0.4×	325 0.8×	136 0.4×	16	2.6k
Frédéric Cumin Switzerland	25	857 0.9×	588 1.3×	76 0.2×	221 0.6×	174 0.5×	55	2.2k
Grazia Chiellini Italy	22	834 0.8×	701 1.5×	107 0.3×	338 0.8×	77 0.2×	47	1.8k

Countries citing papers authored by Graeme Semple

Since Specialization

Citations

This map shows the geographic impact of Graeme Semple's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Graeme Semple with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Graeme Semple more than expected).

Fields of papers citing papers by Graeme Semple

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Graeme Semple. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Graeme Semple. The network helps show where Graeme Semple may publish in the future.

Co-authorship network of co-authors of Graeme Semple

This figure shows the co-authorship network connecting the top 25 collaborators of Graeme Semple. A scholar is included among the top collaborators of Graeme Semple based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Graeme Semple. Graeme Semple is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ren, Albert, Xiuwen Zhu, Konrad Feichtinger, et al.. (2019). Discovery of a lead series of potent benzodiazepine 5-HT2C receptor agonists with high selectivity in functional and binding assays. Bioorganic & Medicinal Chemistry Letters. 30(5). 126929–126929. 3 indexed citations

Gaidarov, Ibragim, John W. Adams, John Frazer, et al.. (2018). Angiotensin (1–7) does not interact directly with MAS1, but can potently antagonize signaling from the AT1 receptor. Cellular Signalling. 50. 9–24. 40 indexed citations

Schrader, Thomas O., Albert Ren, Konrad Feichtinger, et al.. (2016). Tetrahydroquinoline-based tricyclic amines as potent and selective agonists of the 5-HT2C receptor. Bioorganic & Medicinal Chemistry Letters. 26(24). 5877–5882. 6 indexed citations

Ullman, Brett R., Konrad Feichtinger, John Frazer, et al.. (2012). Identification of fused bicyclic heterocycles as potent and selective 5-HT2A receptor antagonists for the treatment of insomnia. Bioorganic & Medicinal Chemistry Letters. 22(5). 1870–1873. 9 indexed citations

Semple, Graeme, Albert Ren, Beatriz Fioravanti, et al.. (2011). Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control. Bioorganic & Medicinal Chemistry Letters. 21(10). 3134–3141. 53 indexed citations

Offermanns, Stefan, Steven L. Colletti, Timothy W. Lovenberg, et al.. (2011). International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B). Pharmacological Reviews. 63(2). 269–290. 161 indexed citations

Semple, Graeme, Juerg Lehmann, Albert Ren, et al.. (2011). Discovery of a second generation agonist of the orphan G-protein coupled receptor GPR119 with an improved profile. Bioorganic & Medicinal Chemistry Letters. 22(4). 1750–1755. 39 indexed citations

Boatman, P. Douglas, Thomas O. Schrader, Benjamin Johnson, et al.. (2010). Potent tricyclic pyrazole tetrazole agonists of the nicotinic acid receptor (GPR109a). Bioorganic & Medicinal Chemistry Letters. 20(9). 2797–2800. 23 indexed citations

Semple, Graeme, Thuy-Anh Tran, Sangdon Han, et al.. (2009). Pyrimidine-based antagonists of h-MCH-R1 derived from ATC0175: In vitro profiling and in vivo evaluation. Bioorganic & Medicinal Chemistry Letters. 19(21). 6166–6171. 3 indexed citations

10.

Richman, Jeremy G., Ibragim Gaidarov, Jill S. Cameron, et al.. (2007). Nicotinic Acid Receptor Agonists Differentially Activate Downstream Effectors. Journal of Biological Chemistry. 282(25). 18028–18036. 87 indexed citations

11.

Skinner, Philip J., Peter J. Webb, Young‐Jun Shin, et al.. (2007). Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a. Bioorganic & Medicinal Chemistry Letters. 17(20). 5620–5623. 32 indexed citations

12.

Funakoshi, Takeo, Shigeyuki Chaki, Izumi Iida, et al.. (2006). Identification of 4-amino-2-cyclohexylaminoquinazolines as metabolically stable melanin-concentrating hormone receptor 1 antagonists. Bioorganic & Medicinal Chemistry. 14(10). 3307–3319. 28 indexed citations

13.

Funakoshi, Takeo, Shigeyuki Chaki, Graeme Semple, et al.. (2005). Discovery of 4-(dimethylamino)quinazolines as potent and selective antagonists for the melanin-concentrating hormone receptor 1. Bioorganic & Medicinal Chemistry Letters. 15(10). 2565–2569. 23 indexed citations

14.

Funakoshi, Takeo, Shigeyuki Chaki, Graeme Semple, et al.. (2005). Lead optimization of 4-(dimethylamino)quinazolines, potent and selective antagonists for the melanin-concentrating hormone receptor 1. Bioorganic & Medicinal Chemistry Letters. 15(17). 3853–3856. 28 indexed citations

15.

Chaki, Shigeyuki, Takeo Funakoshi, Toshiharu Shimazaki, et al.. (2005). Anxiolytic- and Antidepressant-Like Profile of ATC0065 and ATC0175: Nonpeptidic and Orally Active Melanin-Concentrating Hormone Receptor 1 Antagonists. Journal of Pharmacology and Experimental Therapeutics. 313(2). 831–839. 108 indexed citations

16.

Semple, Graeme, et al.. (2003). Synthesis and Biological activity of kappa opioid receptor agonists. Part 2: Preparation of 3-aryl-2-pyridone analogues generated by solution- and solid-phase parallel synthesis methods. Bioorganic & Medicinal Chemistry Letters. 13(6). 1141–1145. 36 indexed citations

17.

Semple, Graeme, et al.. (2002). 3-Aryl pyridone derivatives. Potent and selective kappa opioid receptor agonists. Bioorganic & Medicinal Chemistry Letters. 12(2). 197–200. 5 indexed citations

18.

Semple, Graeme, Doreen M. Ashworth, Andrew Baxter, et al.. (1998). Peptidomimetic aminomethylene ketone inhibitors of interleukin-1β-converting enzyme (ICE). Bioorganic & Medicinal Chemistry Letters. 8(8). 959–964. 27 indexed citations

19.

Yuki, Hidenobu, Akito Nishida, Shinobu Akuzawa, et al.. (1997). YF476 is a new potent and selective gastrin/cholecystokinin‐B receptor antagonist in vitro and in vivo. Alimentary Pharmacology & Therapeutics. 11(1). 113–120. 56 indexed citations

20.

Okamoto, Yoshinori, Hiroyuki Koshio, Mitsuaki Ohta, et al.. (1996). Biological Activity of Analogues of YM022. Novel (3-Amino Substituted Phenyl)urea Derivatives of 1,4-Benzodiazepin-2-one as Gastrin/Cholecystokinin-B Receptor Antagonists.. Chemical and Pharmaceutical Bulletin. 44(7). 1412–1414. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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