Donald S. Middleton

965 citations

45 papers · 625 indexed · h-index 16

Co-authors: Scott E. Denmark Nigel S. Simpkins Atli Thorarensen N.K. Terrett A. J. Boulton Jeremy Robertson Barry Jones A. Mackenzie
Topics: HIV/AIDS drug development and treatment (10 papers)Biochemical and Molecular Research (6 papers)Synthesis of β-Lactam Compounds (5 papers)
Cited by: Organic Chemistry Virology Toxicology
Journals: Journal of the American Chemical Society Journal of Medicinal Chemistry The Journal of Organic Chemistry
Partner nations: United Kingdom United States Canada

In The Last Decade

Donald S. Middleton

45 papers receiving 593 citations

Peers

Countries citing papers authored by Donald S. Middleton

Since Specialization

Citations

This map shows the geographic impact of Donald S. Middleton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Donald S. Middleton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Donald S. Middleton more than expected).

Fields of papers citing papers by Donald S. Middleton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Donald S. Middleton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Donald S. Middleton. The network helps show where Donald S. Middleton may publish in the future.

Co-authorship network of co-authors of Donald S. Middleton

This figure shows the co-authorship network connecting the top 25 collaborators of Donald S. Middleton. A scholar is included among the top collaborators of Donald S. Middleton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Donald S. Middleton. Donald S. Middleton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Non-benzimidazole containing inhibitors of respiratory syncytial virus 2012 ·Bioorganic & Medicinal Chemistry Letters ·David C. Pryde,(unknown),Iain Gardner,Helen Bright,Paul A. Stupple,Sébastien R. G. Galan,(unknown),(unknown),Donald S. Middleton,(unknown),(unknown),Edward J. Murray,Tanya Parkinson,Robert O. Webster	7
2	The design and discovery of novel amide CCR5 antagonists 2009 ·Bioorganic & Medicinal Chemistry Letters ·David C. Pryde,(unknown),David R. Fenwick,Helen J. Mason,(unknown),Peter T. Stephenson,David A. Ellis,(unknown),David W. Gordon,Chris Barber,Anthony Wood,Donald S. Middleton,David C. Blakemore,(unknown),(unknown),(unknown),(unknown),(unknown),Catherine Burt,Wolfgang Klute	16
3	Discovery of a small molecule inhibitor through interference with the gp120–CD4 interaction 2009 ·Bioorganic & Medicinal Chemistry Letters ·D. H. Williams,(unknown),David R. Fenwick,Juin Fok‐Seang,Iain Gardner,Duncan A. Hay,(unknown),Donald S. Middleton,Charles E. Mowbray,Tanya Parkinson,Manos Perros,(unknown),(unknown),Amy Randall,(unknown),Peter T. Stephenson,Thien-Duc Tran,(unknown)	8
4	6 Cytochrome P450 Metabolism and Inhibition: Analysis for Drug Discovery 2009 ·Progress in medicinal chemistry ·Barry Jones,Donald S. Middleton,Kuresh Youdim	7
5	1-Amido-1-phenyl-3-piperidinylbutanes — CCR5 antagonists for the treatment of HIV. Part 1 2009 ·Bioorganic & Medicinal Chemistry Letters ·Chris Barber,David C. Blakemore,(unknown),(unknown),Donald S. Middleton,(unknown)	12
6	1-Amido-1-phenyl-3-piperidinylbutanes – CCR5 antagonists for the treatment of HIV: Part 2 2009 ·Bioorganic & Medicinal Chemistry Letters ·Chris Barber,David C. Blakemore,(unknown),(unknown),Donald S. Middleton,(unknown)	17
7	Design and optimisation of potent gp120-CD4 inhibitors 2009 ·Bioorganic & Medicinal Chemistry Letters ·Thien-Duc Tran,(unknown),(unknown),David R. Fenwick,Juin Fok‐Seang,Iain Gardner,Duncan A. Hay,Manos Perros,(unknown),Donald S. Middleton,Tanya Parkinson,(unknown),(unknown),Amy Randall,Peter T. Stephenson,(unknown),D. H. Williams	8
8	Designing rapid onset selective serotonin re-uptake inhibitors. 2: Structure–activity relationships of substituted (aryl)benzylamines 2008 ·Bioorganic & Medicinal Chemistry Letters ·Donald S. Middleton,Mark D. Andrews,Paul A. Glossop,Geoffrey E. Gymer,David Hepworth,Alan S. Jessiman,Patrick S. Johnson,(unknown),Michael J. Pitcher,(unknown),Alan Stobie,Kim Tang,Paul Morgan	8
9	Optimization of 5‐Aryloxyimidazole Non‐Nucleoside Reverse Transcriptase Inhibitors 2008 ·ChemMedChem ·Lyn H. Jones,(unknown),Romuald Corbau,Duncan A. Hay,Donald S. Middleton,Charles E. Mowbray,(unknown),Manos Perros,Amy Randall,(unknown),Rob Webster,Mike Westby,David J. Williams	8
10	Designing rapid onset selective serotonin re-uptake inhibitors. Part 3: Site-directed metabolism as a strategy to avoid active circulating metabolites: Structure–activity relationships of (thioalkyl)phenoxy benzylamines 2008 ·Bioorganic & Medicinal Chemistry Letters ·Donald S. Middleton,Mark D. Andrews,Paul A. Glossop,Geoffrey E. Gymer,David Hepworth,Alan S. Jessiman,Patrick S. Johnson,(unknown),Alan Stobie,Kim Tang,(unknown),Barry Jones	8
11	Synthesis of Enantiomerically Pure 4-Substituted Riboses 2007 ·Synlett ·David C. Pryde,(unknown),(unknown),(unknown),Rebecca Glen,(unknown),Xiurong Zhang,(unknown),Donald S. Middleton,(unknown),Nicholas C. Smith,Scott C. Sutton	2
12	Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder 2006 ·Bioorganic & Medicinal Chemistry ·David C. Pryde,Andrew S. Cook,(unknown),Lyn H. Jones,(unknown),(unknown),(unknown),(unknown),Alan Stobie,Donald S. Middleton,(unknown),(unknown),(unknown),Peter Stacey,Christopher Kohl,Sara Coggon,Kevin Beaumont	16
13	Highly potent and selective zwitterionic agonists of the δ-opioid receptor. Part 1 2005 ·Bioorganic & Medicinal Chemistry Letters ·Donald S. Middleton,Graham N. Maw,(unknown),Alan S. Jessiman,Patrick S. Johnson,(unknown),(unknown),(unknown),Michael A. Trevethick	10
14	Structure–activity relationships of 1-alkyl-5-(3,4-dichlorophenyl)-5-{2-[3-(substituted)-1-azetidinyl]-ethyl}-2-piperidones. Part 2: Improving oral absorption 2005 ·Bioorganic & Medicinal Chemistry Letters ·Donald S. Middleton,A. Mackenzie,(unknown),(unknown),(unknown),(unknown),Barry Jones	6
15	Designing rapid onset selective serotonin re-uptake inhibitors. Part 1: Structure–activity relationships of substituted (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthaleneamine 2005 ·Bioorganic & Medicinal Chemistry Letters ·Donald S. Middleton,Mark D. Andrews,Paul A. Glossop,Geoffrey E. Gymer,Alan S. Jessiman,Patrick S. Johnson,(unknown),Michael J. Pitcher,(unknown),Alan Stobie,Kim Tang,Paul Morgan	10
16	4-Amino-2-(aryl)-butylbenzamides and Their conformationally constrained analogues. Potent antagonists of the human neurokinin-2 (NK2) receptor 2003 ·Bioorganic & Medicinal Chemistry Letters ·A. Mackenzie,(unknown),Donald S. Middleton,(unknown),(unknown),N.K. Terrett	8
17	ChemInform Abstract: Tandem Inter [4 + 2]/Intra [3 + 2] Cycloadditions. Part 17. The Spiro Mode. Efficient and Highly Selective Synthesis of Azapropellanes. 1998 ·ChemInform ·Scott E. Denmark,Donald S. Middleton	1
18	The tandem cycloaddition chemistry of nitroalkenes 1994 ·Pure and Applied Chemistry ·Scott E. Denmark,Mark E. Schnute,(unknown),Donald S. Middleton,Andreas Stolle	9
19	Total synthesis of (±)-fredericamycin A. Use of radical spirocyclization 1992 ·Journal of the Chemical Society Chemical Communications ·Derrick L. J. Clive,Yong Tao,(unknown),Yongjin Wu,(unknown),Sharon M. Bennett,Christopher N. Boddy,(unknown),(unknown),(unknown),Donald S. Middleton,Christopher J. Nichols,(unknown),(unknown)	17
20	Regioselective Oxidation of Polyalkoxy Naphthalenes: Formation of Naphthoquinones by Ammonium Cerium(IV) Nitrate Oxidation of Methoxymethyl Ethers 1991 ·Israel Journal of Chemistry ·Derrick L. J. Clive,Donald S. Middleton	5

About Donald S. Middleton

Donald S. Middleton is a scholar working on Organic Chemistry, Virology and Pharmacology, having authored 45 papers that have together received 625 indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (10 papers), Biochemical and Molecular Research (6 papers) and Synthesis of β-Lactam Compounds (5 papers). The work is most often cited by research in Organic Chemistry (443 citations), Virology (68 citations) and Toxicology (26 citations). Donald S. Middleton has collaborated with scholars based in United Kingdom, United States and Canada. Frequent co-authors include Scott E. Denmark, Nigel S. Simpkins, Atli Thorarensen, N.K. Terrett, A. J. Boulton, Jeremy Robertson, Barry Jones, A. Mackenzie, Michael J. Begley and Derrick L. J. Clive. Their work appears in journals such as Journal of the American Chemical Society, Journal of Medicinal Chemistry and The Journal of Organic Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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