Michael Shales

11.8k total citations · 2 hit papers
34 papers, 3.7k citations indexed

About

Michael Shales is a scholar working on Molecular Biology, Genetics and Epidemiology. According to data from OpenAlex, Michael Shales has authored 34 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 30 papers in Molecular Biology, 5 papers in Genetics and 4 papers in Epidemiology. Recurrent topics in Michael Shales's work include RNA and protein synthesis mechanisms (12 papers), RNA Research and Splicing (11 papers) and Genomics and Chromatin Dynamics (10 papers). Michael Shales is often cited by papers focused on RNA and protein synthesis mechanisms (12 papers), RNA Research and Splicing (11 papers) and Genomics and Chromatin Dynamics (10 papers). Michael Shales collaborates with scholars based in United States, Canada and Ireland. Michael Shales's co-authors include C. James Ingles, Nevan J. Krogan, Lori A. Allison, Matthew Moyle, Sean R. Collins, Hannes Braberg, Steven J. Triezenberg, Jack Greenblatt, W. Douglas Cress and Jonathan S. Weissman and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Michael Shales

34 papers receiving 3.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases

1985 591 citations Michael Shales, C. James Ingles et al. Cell profile →
Phenotypic Landscape of a Bacterial Cell

2010 509 citations Robert J. Nichols, Śaunak Sen et al. Cell profile →

Peers

Countries citing papers authored by Michael Shales

Since Specialization

Citations

This map shows the geographic impact of Michael Shales's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael Shales with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael Shales more than expected).

Fields of papers citing papers by Michael Shales

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael Shales. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael Shales. The network helps show where Michael Shales may publish in the future.

Co-authorship network of co-authors of Michael Shales

This figure shows the co-authorship network connecting the top 25 collaborators of Michael Shales. A scholar is included among the top collaborators of Michael Shales based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael Shales. Michael Shales is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A Quantitative Genetic Interaction Map of HIV Infection 2020 ·Molecular Cell ·David E. Gordon, Ariane Watson, Assen Roguev, Simin Zheng, Gwendolyn Μ. Jang, (unknown), Jiewei Xu, Jeffrey Guo, Erica Stevenson, Danielle L. Swaney, (unknown), Erik Verschueren, Michael Shales, David C. Crosby, Alan D. Frankel, Alexander Marson, Ivan Marazzi, Gerard Cagney, Nevan J. Krogan	13
2	Quantitative Yeast Genetic Interaction Profiling of Bacterial Effector Proteins Uncovers a Role for the Human Retromer in Salmonella Infection 2018 ·Cell Systems ·Kristin L. Patrick, Jason A. Wojcechowskyj, Samantha L. Bell, (unknown), Tao Jing, (unknown), Pengbiao Xu, (unknown), Jiewei Xu, Michael Shales, David Jimenez‐Morales, Thomas A. Ficht, Paul de Figueiredo, James E. Samuel, Pingwei Li, Nevan J. Krogan, Robert O. Watson	16
3	Genetic interaction mapping in mammalian cells using CRISPR interference 2017 ·Nature Methods ·Dan Du, Assen Roguev, David E. Gordon, Meng Chen, Sihan Chen, Michael Shales, John Paul Shen, Trey Ideker, Prashant Mali, Lei S. Qi, Nevan J. Krogan	114
4	Differential genetic interactions of yeast stress response MAPK pathways 2015 ·Molecular Systems Biology ·Humberto Martı́n, Michael Shales, (unknown), Ping Wei, Marı́a Molina, Dorothea Fiedler, Kevan M. Shokat, Pedro Beltrão, Wendell A. Lim, Nevan J. Krogan	39
5	Genetic Interaction Mapping Reveals a Role for the SWI/SNF Nucleosome Remodeler in Spliceosome Activation in Fission Yeast 2015 ·PLoS Genetics ·Kristin L. Patrick, Colm J. Ryan, Jiewei Xu, Jesse Lipp, (unknown), Assen Roguev, Michael Shales, Nevan J. Krogan, Christine Guthrie	23
6	Quantitative analysis of triple-mutant genetic interactions 2014 ·Nature Protocols ·Hannes Braberg, (unknown), Michael Shales, Jiewei Xu, Kathleen E. Franks-Skiba, (unknown), James E. Haber, Nevan J. Krogan	13
7	Global Mapping of Herpesvirus-Host Protein Complexes Reveals a Transcription Strategy for Late Genes 2014 ·Molecular Cell ·Zoe H. Davis, Erik Verschueren, Gwendolyn Μ. Jang, (unknown), Jeffrey R. Johnson, Jimin Park, John Von Dollen, M. Cyrus Maher, Tasha L. Johnson, W. H. Newton, Stefanie Jäger, Michael Shales, Julie A. Horner, Ryan D. Hernandez, Nevan J. Krogan, Britt A. Glaunsinger	146
8	Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells 2014 ·Genome Medicine ·Elena Tosti, (unknown), Sonja Schaetzlein, Hyun Soo Kim, Colm J. Ryan, Michael Shales, Assen Roguev, Nevan J. Krogan, Deborah Palliser, Michael‐Christopher Keogh, Winfried Edelmann	10
9	Quantitative genetic-interaction mapping in mammalian cells 2013 ·Nature Methods ·Assen Roguev, Dale Talbot, Gian Luca Negri, Michael Shales, Gerard Cagney, Sourav Bandyopadhyay, Barbara Panning, Nevan J. Krogan	79
10	A Lipid E-MAP Identifies Ubx2 as a Critical Regulator of Lipid Saturation and Lipid Bilayer Stress 2013 ·Molecular Cell ·Michał A. Surma, Christian Klose, (unknown), Michael Shales, Caroline Mrejen, (unknown), Hannes Braberg, David E. Gordon, Daniela Vorkel, Christer S. Ejsing, Robert V. Farese, Kai Simons, Nevan J. Krogan, Robert Ernst	111
11	Chemical Genetics of Rapamycin-Insensitive TORC2 in S. cerevisiae 2013 ·Cell Reports ·Joseph I. Kliegman, Dorothea Fiedler, Colm J. Ryan, (unknown), Xiaoyang Su, David M. Thomas, (unknown), (unknown), Michael Shales, Joshua D. Rabinowitz, Nevan J. Krogan, Kevan M. Shokat	26
12	Epistatic relationships reveal the functional organization of yeast transcription factors 2010 ·Molecular Systems Biology ·Jiashun Zheng, Joris J. Benschop, Michael Shales, Patrick Kemmeren, Jack Greenblatt, Gerard Cagney, Frank C. P. Holstege, Hao Li, Nevan J. Krogan	41
13	Phenotypic Landscape of a Bacterial Cell breakdown → 2010 ·Cell ·Robert J. Nichols, Śaunak Sen, (unknown), Pedro Beltrão, Matylda Zietek, Rachna Chaba, (unknown), Krystyna M. Kazmierczak, (unknown), Angela Wong, Michael Shales, Susan T. Lovett, Malcolm E. Winkler, Nevan J. Krogan, Athanasios Typas, Carol A. Gross	509
14	Individual Lysine Acetylations on the N Terminus of Saccharomyces cerevisiae H2A.Z Are Highly but Not Differentially Regulated 2010 ·Journal of Biological Chemistry ·Monika Mehta, Hannes Braberg, Shuyi Wang, (unknown), Michael Shales, Alejandra Solache, Nevan J. Krogan, (unknown)	20
15	A Complex-based Reconstruction of the Saccharomyces cerevisiae Interactome 2009 ·Molecular & Cellular Proteomics ·Haidong Wang, Boyko Kakaradov, Sean R. Collins, (unknown), Dorothea Fiedler, Michael Shales, Kevan M. Shokat, Tobias C. Walther, Nevan J. Krogan, Daphne Koller	71
16	High-throughput, quantitative analyses of genetic interactions in E. coli 2008 ·Nature Methods ·Athanasios Typas, Robert J. Nichols, Deborah A. Siegele, Michael Shales, Sean R. Collins, Bentley Lim, Hannes Braberg, Natsuko Yamamoto, Rikiya Takeuchi, Barry L. Wanner, Hirotada Mori, Jonathan S. Weissman, Nevan J. Krogan, Carol A. Gross	181
17	Splicing and transcription-associated proteins PSF and p54nrb/NonO bind to the RNA polymerase II CTD 2002 ·RNA ·Andrew Emili, Michael Shales, Susan McCracken, (unknown), Philip W. Tucker, Ryûji Kobayashi, Benjamin J. Blencowe, C. James Ingles	160
18	Characterization of the Interaction between the Acidic Activation Domain of VP16 and the RNA Polymerase II Initiation Factor TFIIB 1996 ·Nucleic Acids Research ·Rashi Gupta, Andrew Emili, Guohua Pan, Hua Xiao, Michael Shales, Jack Greenblatt, C. James Ingles	21
19	Reduced binding of TFIID to transcriptionally compromised mutants of VP16 1991 ·Nature ·C. James Ingles, Michael Shales, W. Douglas Cress, Steven J. Triezenberg, Jack Greenblatt	320
20	DNA-Mediated Transfer of an RNA Polymerase II Gene: Reversion of the Temperature-Sensitive Hamster Cell Cycle Mutant TsAF8 by Mammalian DNA 1982 ·Molecular and Cellular Biology ·C. James Ingles, Michael Shales	10

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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