Frank C. P. Holstege

21.1k total citations · 2 hit papers
156 papers, 11.1k citations indexed

About

Frank C. P. Holstege is a scholar working on Molecular Biology, Oncology and Genetics. According to data from OpenAlex, Frank C. P. Holstege has authored 156 papers receiving a total of 11.1k indexed citations (citations by other indexed papers that have themselves been cited), including 119 papers in Molecular Biology, 17 papers in Oncology and 15 papers in Genetics. Recurrent topics in Frank C. P. Holstege's work include Genomics and Chromatin Dynamics (48 papers), RNA Research and Splicing (33 papers) and Fungal and yeast genetics research (25 papers). Frank C. P. Holstege is often cited by papers focused on Genomics and Chromatin Dynamics (48 papers), RNA Research and Splicing (33 papers) and Fungal and yeast genetics research (25 papers). Frank C. P. Holstege collaborates with scholars based in Netherlands, United States and Germany. Frank C. P. Holstege's co-authors include Richard A. Young, Patrick Kemmeren, Marian J.A. Groot Koerkamp, Dik van Leenen, Ezra G. Jennings, Michael R. Green, John J. Wyrick, Eric S. Lander, Tong Ihn Lee and Christoph J. Hengartner and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Frank C. P. Holstege

154 papers receiving 10.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Dissecting the Regulatory Circuitry of a Eukaryotic Genome

1998 1.5k citations Frank C. P. Holstege et al. profile →
Toward a Comprehensive Atlas of the Physical Interactome of Saccharomyces cerevisiae

2007 618 citations Sean R. Collins, Patrick Kemmeren et al. Molecular & Cellular Proteomics profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Frank C. P. Holstege Netherlands	54	8.9k	1.1k	918	835	801	156	11.1k
Edgar Wingender Germany	38	6.8k 0.8×	1.3k 1.2×	947 1.0×	919 1.1×	999 1.2×	146	8.9k
Keith A. Ching United States	24	6.6k 0.7×	1.4k 1.3×	894 1.0×	989 1.2×	1000 1.2×	45	8.8k
Pablo Mínguez Spain	27	6.3k 0.7×	1.0k 0.9×	672 0.7×	1.2k 1.4×	860 1.1×	79	9.0k
Ernest Fraenkel United States	41	7.6k 0.9×	1.2k 1.1×	589 0.6×	573 0.7×	900 1.1×	92	9.7k
Maria Carmo‐Fonseca Portugal	60	10.7k 1.2×	1.3k 1.2×	728 0.8×	877 1.1×	726 0.9×	183	12.5k
Jason Wright United States	12	7.9k 0.9×	1.5k 1.4×	843 0.9×	936 1.1×	914 1.1×	16	9.8k
Stéphane Richard Canada	67	13.1k 1.5×	861 0.8×	1.0k 1.1×	1.4k 1.6×	800 1.0×	182	15.0k
Michiel Vermeulen Netherlands	53	10.5k 1.2×	1.3k 1.2×	1.1k 1.2×	1.0k 1.2×	680 0.8×	182	12.2k
Adriaan B. Houtsmuller Netherlands	56	6.1k 0.7×	1.2k 1.2×	1.2k 1.3×	745 0.9×	476 0.6×	158	8.9k
Minoru S.H. Ko United States	59	9.6k 1.1×	2.0k 1.9×	685 0.7×	872 1.0×	914 1.1×	160	12.3k

Countries citing papers authored by Frank C. P. Holstege

Since Specialization

Citations

This map shows the geographic impact of Frank C. P. Holstege's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank C. P. Holstege with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank C. P. Holstege more than expected).

Fields of papers citing papers by Frank C. P. Holstege

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank C. P. Holstege. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank C. P. Holstege. The network helps show where Frank C. P. Holstege may publish in the future.

Co-authorship network of co-authors of Frank C. P. Holstege

This figure shows the co-authorship network connecting the top 25 collaborators of Frank C. P. Holstege. A scholar is included among the top collaborators of Frank C. P. Holstege based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank C. P. Holstege. Frank C. P. Holstege is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

DeMartino, Jeff, Michael T. Meister, Lindy L. Visser, et al.. (2023). Single-cell transcriptomics reveals immune suppression and cell states predictive of patient outcomes in rhabdomyosarcoma. Nature Communications. 14(1). 3074–3074. 23 indexed citations

Visser, Lindy L., Margit Bleijs, Thanasis Margaritis, et al.. (2023). Ewing Sarcoma Single-cell Transcriptome Analysis Reveals Functionally Impaired Antigen-presenting Cells. Cancer Research Communications. 3(10). 2158–2169. 11 indexed citations

Verwiel, Eugène T.P., Ronald R. de Krijger, Hindrik H. D. Kerstens, et al.. (2022). Molecular Characterization Reveals Subclasses of 1q Gain in Intermediate Risk Wilms Tumors. Cancers. 14(19). 4872–4872. 1 indexed citations

Aristizabal, Maria J., Nancy Lévesque, Dheva Setiaputra, et al.. (2022). A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans. Genetics. 222(3).

Bao, Xue, Martijn C. Koorengevel, Marian J.A. Groot Koerkamp, et al.. (2021). Shortening of membrane lipid acyl chains compensates for phosphatidylcholine deficiency in choline‐auxotroph yeast. The EMBO Journal. 40(20). e107966–e107966. 21 indexed citations

Brok, Mariël, et al.. (2020). Genome‐wide off‐rates reveal how DNA binding dynamics shape transcription factor function. Molecular Systems Biology. 16(10). e9885–e9885. 12 indexed citations

Kanter, Jurrian K. de, Philip Lijnzaad, Tito Candelli, Thanasis Margaritis, & Frank C. P. Holstege. (2019). CHETAH: a selective, hierarchical cell type identification method for single-cell RNA sequencing. Nucleic Acids Research. 47(16). e95–e95. 163 indexed citations

Welsem, Tibor van, Reggy Ekkebus, Su Ming Sun, et al.. (2018). Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism. Nucleic Acids Research. 46(21). 11251–11261. 26 indexed citations

Hornsveld, Marten, Lydia M.M. Smits, Maaike Meerlo, et al.. (2018). FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression. Cancer Research. 78(9). 2356–2369. 60 indexed citations

10.

Gómez-Herreros, Fernando, Thanasis Margaritis, Olga Rodríguez‐Galán, et al.. (2017). The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation. Nucleic Acids Research. 45(16). 9302–9318. 12 indexed citations

11.

O’Duibhir, Eoghan, Philip Lijnzaad, Dik van Leenen, et al.. (2016). Molecular mechanisms that distinguish TFIID housekeeping from regulatable SAGA promoters. The EMBO Journal. 36(3). 274–290. 29 indexed citations

12.

Steenbeek, Frank G. van, Guy C. M. Grinwis, Robert P. Favier, et al.. (2014). Aberrant Expression and Distribution of Enzymes of the Urea Cycle and Other Ammonia Metabolizing Pathways in Dogs with Congenital Portosystemic Shunts. PLoS ONE. 9(6). e100077–e100077. 14 indexed citations

13.

Pijnappel, W.W.M. Pim, Daniel Esch, Marijke Baltissen, et al.. (2013). A central role for TFIID in the pluripotent transcription circuitry. Nature. 495(7442). 516–519. 64 indexed citations

14.

Zheng, Jiashun, Joris J. Benschop, Michael Shales, et al.. (2010). Epistatic relationships reveal the functional organization of yeast transcription factors. Molecular Systems Biology. 6(1). 420–420. 41 indexed citations

15.

Werven, Folkert J. van, Hetty A.A.M. van Teeffelen, Frank C. P. Holstege, & H. T. Marc Timmers. (2009). Distinct promoter dynamics of the basal transcription factor TBP across the yeast genome. Nature Structural & Molecular Biology. 16(10). 1043–1048. 68 indexed citations

16.

Bakel, Harm van, Folkert J. van Werven, Marijana Radonjić, et al.. (2008). Improved genome-wide localization by ChIP-chip using double-round T7 RNA polymerase-based amplification. Nucleic Acids Research. 36(4). e21–e21. 36 indexed citations

17.

Collins, Sean R., Patrick Kemmeren, Xuechu Zhao, et al.. (2007). Toward a Comprehensive Atlas of the Physical Interactome of Saccharomyces cerevisiae. Molecular & Cellular Proteomics. 6(3). 439–450. 618 indexed citations breakdown →

18.

Roepman, Paul, Patrick Kemmeren, Lodewijk F.A. Wessels, Piet J. Slootweg, & Frank C. P. Holstege. (2006). Multiple Robust Signatures for Detecting Lymph Node Metastasis in Head and Neck Cancer. Cancer Research. 66(4). 2361–2366. 72 indexed citations

19.

Andrau, Jean‐Christophe, et al.. (2002). Mot1p is essential for TBP recruitment to selected promoters during in vivo gene activation. The EMBO Journal. 21(19). 5173–5183. 50 indexed citations

20.

Verdaasdonk, Rudolf M., E. Jansen, Frank C. P. Holstege, & Cornelius Borst. (1991). Mechanism of CW Nd:YAG laser recanalization with modified fiber tips: Influence of temperature and axial force on tissue penetration in vitro. Lasers in Surgery and Medicine. 11(3). 204–212. 12 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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