Michael A. Mohutsky

959 total citations
34 papers, 716 citations indexed

About

Michael A. Mohutsky is a scholar working on Pharmacology, Oncology and Computational Theory and Mathematics. According to data from OpenAlex, Michael A. Mohutsky has authored 34 papers receiving a total of 716 indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Pharmacology, 17 papers in Oncology and 6 papers in Computational Theory and Mathematics. Recurrent topics in Michael A. Mohutsky's work include Pharmacogenetics and Drug Metabolism (27 papers), Drug Transport and Resistance Mechanisms (15 papers) and Drug-Induced Hepatotoxicity and Protection (10 papers). Michael A. Mohutsky is often cited by papers focused on Pharmacogenetics and Drug Metabolism (27 papers), Drug Transport and Resistance Mechanisms (15 papers) and Drug-Induced Hepatotoxicity and Protection (10 papers). Michael A. Mohutsky collaborates with scholars based in United States, United Kingdom and Singapore. Michael A. Mohutsky's co-authors include Steven Wrighton, Stephen D. Hall, Gary W. Elmer, Annie Lam, Barbara J. Ring, Jenny Y. Chien, John Harrelson, Jialin Mao, John W. Miller and Gail D. Anderson and has published in prestigious journals such as Journal of Pharmacology and Experimental Therapeutics, International Journal of Pharmaceutics and Biochemical Pharmacology.

In The Last Decade

Michael A. Mohutsky

33 papers receiving 689 citations

Peers

Michael A. Mohutsky

PHARM

ONCOL

CTM

PPCH

Susan Wong United States

Jouko Uusitalo Finland

Jingjing Yu United States

Gary L. Skiles United States

Ke Lan China

Anima Ghosal United States

Stephanie D. Turner United States

Timothy J. Strelevitz United States

R. Foti United States

Susan Wong United States

Michael A. Mohutsky

314 ×0.7

PHARM

248 ×1.2

ONCOL

220 ×1.3

55 ×0.6

CTM

98 ×1.4

PPCH

Citations per year, relative to Michael A. Mohutsky Michael A. Mohutsky (= 1×) peers Susan Wong

Countries citing papers authored by Michael A. Mohutsky

Since Specialization

Citations

This map shows the geographic impact of Michael A. Mohutsky's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael A. Mohutsky with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael A. Mohutsky more than expected).

Fields of papers citing papers by Michael A. Mohutsky

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael A. Mohutsky. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael A. Mohutsky. The network helps show where Michael A. Mohutsky may publish in the future.

Co-authorship network of co-authors of Michael A. Mohutsky

This figure shows the co-authorship network connecting the top 25 collaborators of Michael A. Mohutsky. A scholar is included among the top collaborators of Michael A. Mohutsky based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael A. Mohutsky. Michael A. Mohutsky is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Mohutsky, Michael A., et al.. (2026). Profiling RNA metabolism to understand tissue and subcellular clearance of therapeutic RNA. Drug Metabolism and Disposition. 54(3). 100243–100243.

Posada, Maria M., et al.. (2019). The Effect of Promiscuous Aggregation on in Vitro Drug Metabolism Assays. Pharmaceutical Research. 36(12). 170–170. 1 indexed citations

Posada, Maria M., et al.. (2018). Mechanistic understanding of the phase behavior of supersaturated solutions of poorly water-soluble drugs. International Journal of Pharmaceutics. 543(1-2). 29–37. 25 indexed citations

Zhou, Xin, Yu‐Hua Hui, Michael A. Mohutsky, et al.. (2018). In Vitro and In Vivo Correlation of Hepatic Fraction of Metabolism by P450 in Dogs. Journal of Pharmaceutical Sciences. 108(2). 1017–1026. 2 indexed citations

Morse, Bridget L., Jingqi Bao, Michael A. Mohutsky, et al.. (2018). Hepatic Organic Anion Transporting Polypeptide–Mediated Clearance in the Beagle Dog: Assessing In Vitro–In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance. Drug Metabolism and Disposition. 47(3). 215–226. 17 indexed citations

Hariparsad, Niresh, Diane Ramsden, Jairam Palamanda, et al.. (2017). Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive Control. Drug Metabolism and Disposition. 45(10). 1049–1059. 33 indexed citations

Mohutsky, Michael A., et al.. (2017). The Impact of the Hepatocyte-to-Plasma pH Gradient on the Prediction of Hepatic Clearance and Drug-Drug Interactions for CYP2C9 and CYP3A4 Substrates. Drug Metabolism and Disposition. 45(9). 1008–1018. 14 indexed citations

Mohutsky, Michael A., et al.. (2016). The Impact of the Hepatocyte-to-Plasma pH Gradient on the Prediction of Hepatic Clearance and Drug-Drug Interactions for CYP2D6 Substrates. Drug Metabolism and Disposition. 44(11). 1819–1827. 17 indexed citations

Zamek‐Gliszczynski, Maciej J., Michael A. Mohutsky, Jessica Rehmel, & Alice Ke. (2014). Investigational Small-Molecule Drug Selectively Suppresses Constitutive CYP2B6 Activity at the Gene Transcription Level: Physiologically Based Pharmacokinetic Model Assessment of Clinical Drug Interaction Risk. Drug Metabolism and Disposition. 42(6). 1008–1015. 16 indexed citations

10.

Ring, Barbara J., Steven Wrighton, & Michael A. Mohutsky. (2014). Reversible Mechanisms of Enzyme Inhibition and Resulting Clinical Significance. Methods in molecular biology. 1113. 37–56. 35 indexed citations

11.

Mao, Jialin, Michael A. Mohutsky, John Harrelson, Steven Wrighton, & Stephen D. Hall. (2012). Predictions of Cytochrome P450-Mediated Drug-Drug Interactions Using Cryopreserved Human Hepatocytes: Comparison of Plasma and Protein-Free Media Incubation Conditions. Drug Metabolism and Disposition. 40(4). 706–716. 30 indexed citations

12.

Taxak, Nikhil, Prashant Desai, Bhargav A. Patel, et al.. (2012). Metabolic‐intermediate complex formation with cytochrome P450: Theoretical studies in elucidating the reaction pathway for the generation of reactive nitroso intermediate. Journal of Computational Chemistry. 33(21). 1740–1747. 32 indexed citations

13.

Mao, Jialin, Michael A. Mohutsky, John Harrelson, Steven Wrighton, & Stephen D. Hall. (2011). Prediction of CYP3A-Mediated Drug-Drug Interactions Using Human Hepatocytes Suspended in Human Plasma. Drug Metabolism and Disposition. 39(4). 591–602. 45 indexed citations

14.

Danielson, Matthew L., Prashant Desai, Michael A. Mohutsky, Steven Wrighton, & Markus A. Lill. (2011). Potentially increasing the metabolic stability of drug candidates via computational site of metabolism prediction by CYP2C9: The utility of incorporating protein flexibility via an ensemble of structures. European Journal of Medicinal Chemistry. 46(9). 3953–3963. 20 indexed citations

15.

Dennison, Jennifer B., Michael A. Mohutsky, Robert J. Barbuch, Steven Wrighton, & Stephen D. Hall. (2008). Apparent High CYP3A5 Expression Is Required for Significant Metabolism of Vincristine by Human Cryopreserved Hepatocytes. Journal of Pharmacology and Experimental Therapeutics. 327(1). 248–257. 28 indexed citations

16.

Hashizume, Takanori, Yang Xu, Michael A. Mohutsky, et al.. (2007). Identification of human UDP-glucuronosyltransferases catalyzing hepatic 1α,25-dihydroxyvitamin D3 conjugation. Biochemical Pharmacology. 75(5). 1240–1250. 24 indexed citations

17.

Mohutsky, Michael A., Gail D. Anderson, John W. Miller, & Gary W. Elmer. (2006). Ginkgo biloba: Evaluation of CYP2C9 Drug Interactions In Vitro and In Vivo. American Journal of Therapeutics. 13(1). 24–31. 54 indexed citations

18.

Mohutsky, Michael A., Jenny Y. Chien, Barbara J. Ring, & Steven Wrighton. (2006). Predictions of the In Vivo Clearance of Drugs from Rate of Loss Using Human Liver Microsomes for Phase I and Phase II Biotransformations. Pharmaceutical Research. 23(4). 654–662. 40 indexed citations

19.

Mohutsky, Michael A., et al.. (2005). THE USE OF A SUBSTRATE CASSETTE STRATEGY TO IMPROVE THE CAPACITY AND THROUGHPUT OF CYTOCHROME P450 INDUCTION STUDIES IN HUMAN HEPATOCYTES. Drug Metabolism and Disposition. 33(7). 920–923. 7 indexed citations

20.

Chien, Jenny Y., Michael A. Mohutsky, & Steven Wrighton. (2003). Physiological Approaches to the Prediction of Drug-Drug Interactions in Study Populations. Current Drug Metabolism. 4(5). 347–356. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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