Kenneth E. Thummel

27.1k total citations · 6 hit papers
263 papers, 20.2k citations indexed

About

Kenneth E. Thummel is a scholar working on Pharmacology, Oncology and Pediatrics, Perinatology and Child Health. According to data from OpenAlex, Kenneth E. Thummel has authored 263 papers receiving a total of 20.2k indexed citations (citations by other indexed papers that have themselves been cited), including 153 papers in Pharmacology, 85 papers in Oncology and 54 papers in Pediatrics, Perinatology and Child Health. Recurrent topics in Kenneth E. Thummel's work include Pharmacogenetics and Drug Metabolism (142 papers), Drug Transport and Resistance Mechanisms (80 papers) and Pharmacological Effects and Toxicity Studies (45 papers). Kenneth E. Thummel is often cited by papers focused on Pharmacogenetics and Drug Metabolism (142 papers), Drug Transport and Resistance Mechanisms (80 papers) and Pharmacological Effects and Toxicity Studies (45 papers). Kenneth E. Thummel collaborates with scholars based in United States, United Kingdom and Canada. Kenneth E. Thummel's co-authors include Erin G. Schuetz, Evan D. Kharasch, Kent L. Kunze, Danny D. Shen, Yvonne S. Lin, Jatinder K. Lamba, G. Wilkinson, Mary F. Paine, Paul B. Watkins and James D. Perkins and has published in prestigious journals such as New England Journal of Medicine, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

Kenneth E. Thummel

261 papers receiving 19.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

2001 1.8k citations Kenneth E. Thummel et al. profile →
Effect of VKORC1 Haplotypes on Transcriptional Regulation and Warfarin Dose

2005 988 citations Deborah A. Nickerson, Kenneth E. Thummel et al. profile →
Genetic contribution to variable human CYP3A-mediated metabolism

2002 798 citations Yvonne S. Lin, Kenneth E. Thummel et al. profile →
IN VITRO AND IN VIVO DRUG INTERACTIONS INVOLVING HUMAN CYP3A

1998 703 citations Kenneth E. Thummel et al. profile →
Characterization of Interintestinal and Intraintestinal Variations in Human CYP3A-Dependent Metabolism

1997 645 citations Mary F. Paine, Danny D. Shen et al. profile →
Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism*

1996 509 citations Kenneth E. Thummel, Mary F. Paine et al. Clinical Pharmacology & Therapeutics profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Kenneth E. Thummel United States	73	11.5k	7.2k	4.7k	3.1k	1.9k	263	20.2k
Paul B. Watkins United States	73	11.5k 1.0×	6.2k 0.9×	3.2k 0.7×	3.5k 1.1×	1.4k 0.7×	246	19.9k
Erin G. Schuetz United States	77	9.8k 0.9×	9.7k 1.3×	4.0k 0.9×	4.7k 1.5×	2.5k 1.3×	198	19.9k
Ann K. Daly United Kingdom	74	9.9k 0.9×	4.5k 0.6×	2.3k 0.5×	4.3k 1.4×	2.9k 1.5×	282	20.5k
Ulrich M. Zanger Germany	74	10.1k 0.9×	6.8k 0.9×	3.1k 0.7×	5.1k 1.6×	1.5k 0.8×	197	19.8k
Philippe Beaune France	75	9.2k 0.8×	5.7k 0.8×	2.3k 0.5×	5.1k 1.6×	1.1k 0.6×	352	18.7k
Steven Wrighton United States	71	11.1k 1.0×	6.7k 0.9×	2.6k 0.6×	3.9k 1.2×	1.5k 0.8×	172	17.1k
Michel Eichelbaum Germany	87	12.0k 1.0×	11.4k 1.6×	6.8k 1.5×	4.7k 1.5×	1.6k 0.8×	335	25.4k
Ivar Roots Germany	68	5.9k 0.5×	4.9k 0.7×	3.3k 0.7×	4.7k 1.5×	836 0.4×	253	16.4k
Pertti J. Neuvonen Finland	84	10.9k 0.9×	8.1k 1.1×	5.7k 1.2×	3.1k 1.0×	2.3k 1.2×	506	26.6k
Jürgen Brockmöller Germany	65	5.1k 0.4×	4.0k 0.6×	2.7k 0.6×	4.0k 1.3×	842 0.4×	236	13.8k

Countries citing papers authored by Kenneth E. Thummel

Since Specialization

Citations

This map shows the geographic impact of Kenneth E. Thummel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kenneth E. Thummel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kenneth E. Thummel more than expected).

Fields of papers citing papers by Kenneth E. Thummel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kenneth E. Thummel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kenneth E. Thummel. The network helps show where Kenneth E. Thummel may publish in the future.

Co-authorship network of co-authors of Kenneth E. Thummel

This figure shows the co-authorship network connecting the top 25 collaborators of Kenneth E. Thummel. A scholar is included among the top collaborators of Kenneth E. Thummel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kenneth E. Thummel. Kenneth E. Thummel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Clarke, John, Dandan Tian, Trevor O. Kirby, et al.. (2023). Co‐consuming green tea with raloxifene decreases raloxifene systemic exposure in healthy adult participants. Clinical and Translational Science. 16(10). 1779–1790. 8 indexed citations

Beans, Julie A., et al.. (2022). Retention in a 6-Month Smoking Cessation Study Among Alaska Native and American Indian People. American Indian and Alaska Native Mental Health Research. 29(3). 71–89. 2 indexed citations

Singleton, Rosalyn, Gretchen Day, Timothy K. Thomas, et al.. (2022). Impact of a Prenatal Vitamin D Supplementation Program on Vitamin D Deficiency, Rickets and Early Childhood Caries in an Alaska Native Population. Nutrients. 14(19). 3935–3935. 5 indexed citations

Boyer, Bert B., Scarlett E. Hopkins, Howard W. Wiener, et al.. (2021). Habitual Intake of Marine-Derived n-3 PUFAs is Inversely Associated with a Cardiometabolic Inflammatory Profile in Yup'ik Alaska Native People. Journal of Nutrition. 152(3). 844–855. 6 indexed citations

Best, Cora M., Leila R. Zelnick, Kenneth E. Thummel, et al.. (2021). Serum Vitamin D: Correlates of Baseline Concentration and Response to Supplementation in VITAL-DKD. The Journal of Clinical Endocrinology & Metabolism. 107(2). 525–537. 10 indexed citations

Hsu, Simon, Leila R. Zelnick, Yvonne S. Lin, et al.. (2021). Validation of the 24,25-dihydroxyvitamin D3 to 25-hydroxyvitamin D3 ratio as a biomarker of 25-hydroxyvitamin D3 clearance. The Journal of Steroid Biochemistry and Molecular Biology. 217. 106047–106047. 6 indexed citations

Hsu, Simon, Leila R. Zelnick, Yvonne S. Lin, et al.. (2020). Differences in 25-Hydroxyvitamin D Clearance by eGFR and Race: A Pharmacokinetic Study. Journal of the American Society of Nephrology. 32(1). 188–198. 15 indexed citations

Jolliffe, David A., Zhican Wang, Nazanin Zounemat Kermani, et al.. (2020). Vitamin D Metabolism is Dysregulated in Asthma and Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 202(3). 371–382. 52 indexed citations

Best, Cora M., Thomas J. Laha, Leila R. Zelnick, et al.. (2020). Vitamin D in human serum and adipose tissue after supplementation. American Journal of Clinical Nutrition. 113(1). 83–91. 17 indexed citations

10.

Claw, Katrina G., Julie A. Beans, Seung‐been Lee, et al.. (2019). Pharmacogenomics of Nicotine Metabolism: Novel CYP2A6 and CYP2B6 Genetic Variation Patterns in Alaska Native and American Indian Populations. Nicotine & Tobacco Research. 22(6). 910–918. 15 indexed citations

11.

Yin, Jia, David J. Wagner, Bhagwat Prasad, et al.. (2019). Renal secretion of hydrochlorothiazide involves organic anion transporter 1/3, organic cation transporter 2, and multidrug and toxin extrusion protein 2-K. American Journal of Physiology-Renal Physiology. 317(4). F805–F814. 9 indexed citations

12.

Ryman, Tove K., Allan E. Rettie, Scarlett E. Hopkins, et al.. (2017). Dietary Vitamin K and Association with Hepatic Vitamin K Status in a Yup'ik Study Population from Southwestern Alaska. Molecular Nutrition & Food Research. 62(3). 6 indexed citations

13.

Ryman, Tove K., Bert B. Boyer, Scarlett E. Hopkins, et al.. (2017). Association between iq’mik smokeless tobacco use and cardiometabolic risk profile among Yup’ik Alaska Native people. Ethnicity and Health. 23(5). 488–502. 5 indexed citations

14.

O’Brien, Diane M., Kenneth E. Thummel, Lisa Bulkow, et al.. (2016). Declines in traditional marine food intake and vitamin D levels from the 1960s to present in young Alaska Native women. Public Health Nutrition. 20(10). 1738–1745. 30 indexed citations

15.

Canestaro, William J., Melissa A. Austin, & Kenneth E. Thummel. (2014). Genetic factors affecting statin concentrations and subsequent myopathy: a HuGENet systematic review. Genetics in Medicine. 16(11). 810–819. 57 indexed citations

16.

Zheng, Songmao, Thomas R. Easterling, Jason G. Umans, et al.. (2012). Pharmacokinetics of Tacrolimus During Pregnancy. Therapeutic Drug Monitoring. 34(6). 660–670. 80 indexed citations

17.

Dixit, Vaishali, Niresh Hariparsad, Fang Li, et al.. (2007). Cytochrome P450 Enzymes and Transporters Induced by Anti-Human Immunodeficiency Virus Protease Inhibitors in Human Hepatocytes: Implications for Predicting Clinical Drug Interactions. Drug Metabolism and Disposition. 35(10). 1853–1859. 121 indexed citations

18.

Tran, Agnès, Elisabeth Rey, Gérard Pons, et al.. (1997). Influence of stiripentol on cytochrome P450-mediated metabolic pathways in humans: In vitro and in vivo comparison and calculation of in vivo inhibition constants*. Clinical Pharmacology & Therapeutics. 62(5). 490–504. 89 indexed citations

19.

Thummel, Kenneth E., Evan D. Kharasch, Terry Podoll, & Kent L. Kunze. (1993). Human liver microsomal enflurane defluorination catalyzed by cytochrome P-450 2E1.. Drug Metabolism and Disposition. 21(2). 350–357. 79 indexed citations

20.

Thummel, Kenneth E., et al.. (1991). Activation of acetaminophen-reactive metabolite formation by methylxanthines and known cytochrome P-450 activators.. Drug Metabolism and Disposition. 19(5). 966–971. 10 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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