Gary L. Skiles

1.5k total citations
31 papers, 1.1k citations indexed

About

Gary L. Skiles is a scholar working on Molecular Biology, Pharmacology and Organic Chemistry. According to data from OpenAlex, Gary L. Skiles has authored 31 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 12 papers in Pharmacology and 7 papers in Organic Chemistry. Recurrent topics in Gary L. Skiles's work include Pharmacogenetics and Drug Metabolism (12 papers), Drug Transport and Resistance Mechanisms (5 papers) and Pharmacological Effects and Toxicity Studies (5 papers). Gary L. Skiles is often cited by papers focused on Pharmacogenetics and Drug Metabolism (12 papers), Drug Transport and Resistance Mechanisms (5 papers) and Pharmacological Effects and Toxicity Studies (5 papers). Gary L. Skiles collaborates with scholars based in United States, United Kingdom and Germany. Gary L. Skiles's co-authors include Garold S. Yost, Magang Shou, Lilly Xu, Donglu Zhang, Yang Xu, W. Griffith Humphreys, Haiying Zhang, Raju Subramanian, Weiping Zhao and Kenneth L. Ray and has published in prestigious journals such as Journal of Pharmacology and Experimental Therapeutics, Toxicology and Applied Pharmacology and Toxicological Sciences.

In The Last Decade

Gary L. Skiles

30 papers receiving 1.1k citations

Peers

Gary L. Skiles
Michael Malfatti United States
Shangara S. Dehal United States
John C. L. Erve United States
David E. Amacher United States
Dieter Lang Germany
George Hammons United States
Rasmy Talaat United States
Thomas N. Thompson United States
Gloria Y. Kwei United States
Richard H. Reitz United States
Michael Malfatti United States
Gary L. Skiles
Citations per year, relative to Gary L. Skiles Gary L. Skiles (= 1×) peers Michael Malfatti

Countries citing papers authored by Gary L. Skiles

Since Specialization
Citations

This map shows the geographic impact of Gary L. Skiles's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gary L. Skiles with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gary L. Skiles more than expected).

Fields of papers citing papers by Gary L. Skiles

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gary L. Skiles. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gary L. Skiles. The network helps show where Gary L. Skiles may publish in the future.

Co-authorship network of co-authors of Gary L. Skiles

This figure shows the co-authorship network connecting the top 25 collaborators of Gary L. Skiles. A scholar is included among the top collaborators of Gary L. Skiles based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Gary L. Skiles. Gary L. Skiles is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Edson, Katheryne Z., et al.. (2016). Determination of Etelcalcetide Biotransformation and Hemodialysis Kinetics to Guide the Timing of Its Dosing. Kidney International Reports. 1(1). 24–33. 17 indexed citations
2.
Subramanian, Raju, Xiaochun Zhu, M. Benjamin Hock, et al.. (2016). Pharmacokinetics, Biotransformation, and Excretion of [14C]Etelcalcetide (AMG 416) Following a Single Microtracer Intravenous Dose in Patients with Chronic Kidney Disease on Hemodialysis. Clinical Pharmacokinetics. 56(2). 179–192. 21 indexed citations
3.
Subramanian, Raju, Xiaochun Zhu, Steven W. Louie, et al.. (2016). Nonclinical Pharmacokinetics, Disposition, and Drug-Drug Interaction Potential of a Novel d-Amino Acid Peptide Agonist of the Calcium-Sensing Receptor AMG 416 (Etelcalcetide). Drug Metabolism and Disposition. 44(8). 1319–1331. 28 indexed citations
4.
Subramanian, Raju, Keith Bailey, Dan Branstetter, et al.. (2014). P450-Mediated O-Demethylated Metabolite Is Responsible for Rat Hepatobiliary Toxicity of Pyridyltriazine-Containing PI3K Inhibitors. Toxicological Sciences. 142(1). 298–310. 6 indexed citations
5.
Zhu, Xiaochun, J. Greg Slatter, Maurice G. Emery, et al.. (2012). Activity-based exposure comparisons among humans and nonclinical safety testing species in an extensively metabolized drug candidate. Xenobiotica. 43(7). 617–627. 3 indexed citations
6.
Chen, Yuping, Gary L. Skiles, Magang Shou, Dean Hickman, & Faye Hsieh. (2011). A Novel Biotransformation of Alkyl Aminopyrrolidine to Aminopiperidine Ring by Human CYP3A. Drug Metabolism and Disposition. 39(9). 1668–1673. 3 indexed citations
7.
Xu, Lilly, et al.. (2009). Prediction of Human Drug-Drug Interactions from Time-Dependent Inactivation of CYP3A4 in Primary Hepatocytes Using a Population-Based Simulator. Drug Metabolism and Disposition. 37(12). 2330–2339. 67 indexed citations
8.
Shou, Magang, et al.. (2008). Modeling, Prediction, and in Vitro in Vivo Correlation of CYP3A4 Induction. Drug Metabolism and Disposition. 36(11). 2355–2370. 102 indexed citations
10.
Surapaneni, Sekhar, et al.. (2007). Biosynthesis of Drug Metabolites Using Microbes in Hollow Fiber Cartridge Reactors: Case Study of Diclofenac Metabolism by Actinoplanes Species. Drug Metabolism and Disposition. 36(2). 234–240. 41 indexed citations
11.
Zhang, Donglu, Nirmala Raghavan, Shiang-Yuan Chen, et al.. (2007). Reductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and Dogs. Drug Metabolism and Disposition. 36(2). 303–315. 46 indexed citations
12.
Zhu, Mingshe, Li Ma, Donglu Zhang, et al.. (2006). Detection and Characterization of Metabolites in Biological Matrices Using Mass Defect Filtering of Liquid Chromatography/High Resolution Mass Spectrometry Data. Drug Metabolism and Disposition. 34(10). 1722–1733. 168 indexed citations
13.
Skiles, Gary L., et al.. (2001). An ion exchange liquid chromatography/mass spectrometry method for the determination of reduced and oxidized glutathione and glutathione conjugates in hepatocytes. Journal of Pharmaceutical and Biomedical Analysis. 26(1). 131–142. 63 indexed citations
14.
Prahalada, S., A. F. Tarantal, G. S. Harris, et al.. (1997). Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta). Teratology. 55(2). 119–131. 54 indexed citations
15.
Bennett, Gregory D., Benny Amore, Richard H. Finnell, et al.. (1996). Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse.. Journal of Pharmacology and Experimental Therapeutics. 279(3). 1237–1242. 44 indexed citations
16.
Thornton‐Manning, Janice R., et al.. (1993). Metabolism and Bioactivation of 3-Methylindole by Clara Cells, Alveolar Macrophages, and Subcellular Fractions from Rabbit Lungs. Toxicology and Applied Pharmacology. 122(2). 182–190. 17 indexed citations
17.
Ruangyuttikarn, Werawan, Gary L. Skiles, & Garold S. Yost. (1992). Identification of a cysteinyl adduct of oxidized 3-methylindole from goat lung and human liver microsomal proteins. Chemical Research in Toxicology. 5(5). 713–719. 21 indexed citations
18.
Skiles, Gary L., et al.. (1991). Toxicity of 3-Methyleneoxindole, a Proposed Reactive Intermediate in the Metabolism of 3-Methylindole. Advances in experimental medicine and biology. 283. 245–248. 2 indexed citations
19.
Skiles, Gary L., et al.. (1991). Isolation of a mercapturate adduct produced subsequent to glutathione conjugation of bioactivated 3-methylindole. Toxicology and Applied Pharmacology. 108(3). 531–537. 20 indexed citations
20.
Skiles, Gary L., James D. Adams, & Garold S. Yost. (1989). Isolation and identification of 3-hydroxy-3-methyloxindole, the major murine metabolite of 3-methylindole. Chemical Research in Toxicology. 2(4). 254–259. 19 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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