Martyn Frederickson

2.8k citations

39 papers · 1.8k indexed · h-index 20

Impact in

Computational Theory and Mathematics top 1%
- Computational Drug Discovery Methods
Organic Chemistry top 2%
- Asymmetric Synthesis and Catalysis
- Synthesis and Catalytic Reactions
- Carbohydrate Chemistry and Synthesis
- Organic Chemistry Cycloaddition Reactions

Papers in

Organic Chemistry 25
- Carbohydrate Chemistry and Synthesis 7
- Synthesis and Catalytic Reactions 6
- Asymmetric Synthesis and Catalysis 6
- Organic Chemistry Cycloaddition Reactions 6
- Catalytic C–H Functionalization Methods 3
Biotechnology 4

Co-authors: Christopher W. Murray Anne Cleasby Michael J. Hartshorn Ronald Grigg Harren Jhoti Ian J. Tickle Miles Congreve Chris Abell
Journals: Tetrahedron (8 papers)Journal of Medicinal Chemistry (7 papers)Tetrahedron Letters (3 papers)Organic & Biomolecular Chemistry (3 papers)Journal of the Chemical Society Perkin Transactions 1 (2 papers)
Partner nations: United Kingdom Belgium New Zealand

In The Last Decade

Martyn Frederickson

38 papers receiving 1.6k citations

Peers

Countries citing papers authored by Martyn Frederickson

Since Specialization

Citations

This map shows the geographic impact of Martyn Frederickson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Martyn Frederickson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Martyn Frederickson more than expected).

Fields of papers citing papers by Martyn Frederickson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Martyn Frederickson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Martyn Frederickson. The network helps show where Martyn Frederickson may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Martyn Frederickson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Martyn Frederickson Line = papers co-authored together Martyn Frederickson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening approach (XP screen) European Journal of Medicinal Chemistry ·Martyn Frederickson, Merna Elseragy, Dimitrios Evangelopoulos, Kirsty J. McLean, V.N. Buzin, Richard B. Tunnicliffe, Flora Isabel Ramalho Leite Reis, Madeline E. Kavanagh, Sitthivut Charoensutthivarakul, Richard T. Blankley, Colin Levy, Luiz Pedro S. de Carvalho, David Leys, Andrew W. Munro, Anthony G. Coyne, Chris Abell	2022	5
2	Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP) Journal of Medicinal Chemistry ·Emiliano Tamanini, Ildiko M. Buck, Gianni Chessari, Elisabetta Chiarparin, James E. H. Day, Martyn Frederickson, Charlotte Griffiths-Jones, Keisha Hearn, Tom D. Heightman, Aman Iqbal, Christopher N. Johnson, Edward J. Lewis, Vanessa Martins, Torren M. Peakman, Michael Reader, Sharna J. Rich, George A. Ward, Pamela A. Williams, Nicola E. Wilsher	2017	57
3	Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase ACS Medicinal Chemistry Letters ·Christopher N. Johnson, Valério Berdini, Lijs Beke, Pascal Bonnet, Dirk Brehmer, Joseph E. Coyle, M Rino, Martyn Frederickson, Eddy Freyne, Ron Gilissen, C. Hamlett, Steven Howard, Lieven Meerpoel, Rachel McMenamin, Sahil Patel, David C. Rees, Andrew Sharff, T. Varbanova, Tongfei Wu, Joannes T. M. Linders	2014	25
4	Tri-partite complex for axonal transport drug delivery achieves pharmacological effect BMC Neuroscience ·Aaron G. Filler, Garth T. Whiteside, Mark Bacon, Martyn Frederickson, Franklyn A. Howe, Miri Rabinowitz, Alan J. Sokoloff, Terrence W. Deacon, Chris Abell, ASRIYUNI ASMIN, John R. Griffiths, B. Anthony Bell, Andrew Lever	2010	12
5	Application of Fragment Screening by X-ray Crystallography to β-Secretase Journal of Medicinal Chemistry ·Christopher W. Murray, Owen Callaghan, Gianni Chessari, Anne Cleasby, Miles Congreve, Martyn Frederickson, Michael J. Hartshorn, Rachel McMenamin, Sahil Patel, Nicola G. Wallis	2007	106
6	Fragment-Based Discovery of Mexiletine Derivatives as Orally Bioavailable Inhibitors of Urokinase-Type Plasminogen Activator Journal of Medicinal Chemistry ·Martyn Frederickson, Owen Callaghan, Gianni Chessari, Miles Congreve, Faisal Akbar Saenal, A Rody, Rachel McMenamin, Donna-Michelle Smith, M. Vinković, Nicola G. Wallis	2007	39
7	Application of Fragment Screening by X-ray Crystallography to the Discovery of Aminopyridines as Inhibitors of β-Secretase Journal of Medicinal Chemistry ·Miles Congreve, David Aharony, Jeffrey S. Albert, Owen Callaghan, James B. Campbell, Robin A. E. Carr, Gianni Chessari, Faisal Akbar Saenal, Philip D. Edwards, Martyn Frederickson, Rachel McMenamin, Christopher W. Murray, Sahil Patel, Nicola G. Wallis	2007	107
8	(1R,4S,5R)-3-Fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid: the fluoro analogue of the enolate intermediate in the reaction catalyzed by type II dehydroquinases Organic & Biomolecular Chemistry ·Martyn Frederickson, A.W. Roszak, John R. Coggins, Adrian J. Lapthorn, Chris Abell	2004	21
9	Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation Journal of Medicinal Chemistry ·Adrian L. Gill, Martyn Frederickson, Anne Cleasby, Steven J. Woodhead, Maria G. Carr, Andrew Woodhead, Andreas Greiner, Miles Congreve, Lindsay A. Devine, Dominic Tisi, Marc O’Reilly, Lisa C. A. Seavers, Deborah Davis, Jayne Curry, C Darsow, Alessandro Padova, Christopher W. Murray, Robin A. E. Carr, Harren Jhoti	2004	146
10	Design, synthesis and evaluation of bifunctional inhibitors of type II dehydroquinase Organic & Biomolecular Chemistry ·Miguel D. Toscano, Martyn Frederickson, David P. Evans, John R. Coggins, Chris Abell, Concepción González‐Bello	2003	19
11	Enzymic synthesis of 3-[3-13C]dehydroquinic acid Organic & Biomolecular Chemistry ·Martyn Frederickson, Emily J. Parker, John R. Coggins, Chris Abell	2003	2
12	Vinyl fluoride as an isoelectronic replacement for an enolate anion: Inhibition of type II dehydroquinases Chemical Communications ·Martyn Frederickson, John R. Coggins, Chris Abell	2002	13
13	Selective Inhibition of Type II Dehydroquinases The Journal of Organic Chemistry ·Martyn Frederickson, Emily J. Parker, Alastair R. Hawkins, John R. Coggins, Chris Abell	1999	39
14	ELECTROPHILE MEDIATED HETEROATOM CYCLIZATIONS ONTO C-C π-BONDS. PART 2: METAL ION MEDIATED CYCLIZATION Organic Preparations and Procedures International ·Martyn Frederickson, Ronald Grigg	1997	21
15	Palladium (II) catalysed oxime-metallo-nitrone-isoxazolidine cascade reactions of α-imino aldoximes Tetrahedron Letters ·Martyn Frederickson, Ronald Grigg, Mark Thornton‐Pett, James Redpath	1997	15
16	X=Y-ZH systems as potential 1,3-dipoles. Part 49. Catalytic palladium (II) mediated oxime-nitrone-isoxazolidine cascades Tetrahedron ·Martyn Frederickson, Ronald Grigg, Jasothara Markandu, Mark Thornton‐Pett, James Redpath	1997	21
17	Synthesis of (3R)- and (3S)-Fluoro-(4R,5R)-dihydroxy-1-cyclohexene-1-carboxylic acids: The (3R)- and (3S)-fluoro analogues of (−)-shikimic acid Bioorganic & Medicinal Chemistry Letters ·Roger Brettle, Richard Cross, Martyn Frederickson, Edwin Haslam, R.K. Donalbedian, Gareth M. Davies	1996	12
18	On the stereochemical outcome of the reaction between (–)-chorismic acid and diazomethane: absolute proof of stereochemistry of the major pyrazoline by X-ray crystallography of a cyclopropane based derivative Journal of the Chemical Society Perkin Transactions 1 ·Harry Adams, Neil A. Bailey, Martyn Frederickson, Edwin Haslam, Gareth M. Davies, David A. Jude	1996	1
19	5,21-Dimethyl-8,24-pentamethylenedioxy-1,10,17,26-tetra-aza[2,2](mo)2cyclophane Journal of the Chemical Society Perkin Transactions 1 ·Martyn Frederickson, Neil A. Bailey, Harry Adams, Edwin Haslam	1990	1
20	ChemInform Abstract: 5,21‐Dimethyl‐8,24‐pentamethylenedioxy‐1,10,17,26‐tetra‐aza(2,2)(mo)2‐cyclophane. ChemInform ·Martyn Frederickson, Neil A. Bailey, Harry Adams, Edwin Haslam	1990	0

About Martyn Frederickson

Martyn Frederickson is a scholar working on Organic Chemistry, Biotechnology, Biochemistry, Molecular Biology and Pharmacology, having authored 39 papers that have together received 1.8k indexed citations. Recurring topics across this work include Carbohydrate Chemistry and Synthesis (7 papers), Synthesis and Catalytic Reactions (6 papers), Asymmetric Synthesis and Catalysis (6 papers), Organic Chemistry Cycloaddition Reactions (6 papers), Microbial Natural Products and Biosynthesis (4 papers), Chemical Synthesis and Analysis (4 papers), Catalytic C–H Functionalization Methods (3 papers) and Enzyme Structure and Function (3 papers). The work is most often cited by research in Computational Theory and Mathematics (479 citations), Organic Chemistry (832 citations), Pharmaceutical Science (116 citations), Molecular Biology (1.0k citations) and Toxicology (48 citations). Martyn Frederickson has collaborated with scholars based in United Kingdom, Belgium and New Zealand. Frequent co-authors include Christopher W. Murray, Anne Cleasby, Michael J. Hartshorn, Ronald Grigg, Harren Jhoti, Ian J. Tickle, Miles Congreve, Chris Abell, Gianni Chessari and Rachel McMenamin. Their work appears in journals such as Tetrahedron, Journal of Medicinal Chemistry, Tetrahedron Letters, Organic & Biomolecular Chemistry and Journal of the Chemical Society Perkin Transactions 1.

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