Marc O’Reilly

2.7k total citations · 1 hit paper
20 papers, 1.3k citations indexed

About

Marc O’Reilly is a scholar working on Molecular Biology, Materials Chemistry and Computational Theory and Mathematics. According to data from OpenAlex, Marc O’Reilly has authored 20 papers receiving a total of 1.3k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Molecular Biology, 7 papers in Materials Chemistry and 4 papers in Computational Theory and Mathematics. Recurrent topics in Marc O’Reilly's work include Enzyme Structure and Function (7 papers), Computational Drug Discovery Methods (4 papers) and Protein Structure and Dynamics (3 papers). Marc O’Reilly is often cited by papers focused on Enzyme Structure and Function (7 papers), Computational Drug Discovery Methods (4 papers) and Protein Structure and Dynamics (3 papers). Marc O’Reilly collaborates with scholars based in United Kingdom, Netherlands and Russia. Marc O’Reilly's co-authors include L.N. Johnson, Finn P. Holding, Barbara Chaneton, Agnés C. L. Martin, Karen H. Vousden, Achuthanunni Chokkathukalam, Christian Frezza, Eyal Gottlieb, Petra Hillmann and Joseph E. Coyle and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Marc O’Reilly

19 papers receiving 1.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

2012 497 citations Barbara Chaneton, Petra Hillmann et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Marc O’Reilly United Kingdom	15	1.0k	368	219	158	137	20	1.3k
Gillian Paine-Murrieta United States	16	1.4k 1.4×	545 1.5×	323 1.5×	68 0.4×	137 1.0×	18	2.1k
Chad N. Hancock United States	12	1.0k 1.0×	637 1.7×	252 1.2×	60 0.4×	77 0.6×	16	1.4k
Scott J. Novick United States	22	1.3k 1.3×	128 0.3×	242 1.1×	99 0.6×	93 0.7×	41	1.9k
Hariprasad Vankayalapati United States	21	1.5k 1.5×	180 0.5×	257 1.2×	75 0.5×	280 2.0×	61	2.2k
Sukjoon Yoon South Korea	21	702 0.7×	219 0.6×	155 0.7×	123 0.8×	56 0.4×	54	974
William P. Katt United States	22	946 0.9×	602 1.6×	315 1.4×	69 0.4×	213 1.6×	38	1.5k
Rashid Syed United States	14	724 0.7×	258 0.7×	198 0.9×	41 0.3×	143 1.0×	15	1.5k
Richard A. Norman United Kingdom	18	1.0k 1.0×	145 0.4×	269 1.2×	165 1.0×	325 2.4×	26	1.5k
Ariele Viacava Follis United States	16	1.4k 1.3×	133 0.4×	303 1.4×	119 0.8×	123 0.9×	21	1.7k
Xiaonan Zhang Sweden	21	1.2k 1.2×	383 1.0×	475 2.2×	44 0.3×	156 1.1×	65	1.9k

Countries citing papers authored by Marc O’Reilly

Since Specialization

Citations

This map shows the geographic impact of Marc O’Reilly's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Marc O’Reilly with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Marc O’Reilly more than expected).

Fields of papers citing papers by Marc O’Reilly

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Marc O’Reilly. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Marc O’Reilly. The network helps show where Marc O’Reilly may publish in the future.

Co-authorship network of co-authors of Marc O’Reilly

This figure shows the co-authorship network connecting the top 25 collaborators of Marc O’Reilly. A scholar is included among the top collaborators of Marc O’Reilly based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Marc O’Reilly. Marc O’Reilly is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Day, Philip J., Duncan Laverty, Juan A. Bueren‐Calabuig, et al.. (2024). Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design. Structure. 32(8). 1040–1048.e3. 3 indexed citations

Denis, Jeffrey D. St., Gianni Chessari, Anne Cleasby, et al.. (2022). X-ray Screening of an Electrophilic Fragment Library and Application toward the Development of a Novel ERK 1/2 Covalent Inhibitor. Journal of Medicinal Chemistry. 65(18). 12319–12333. 17 indexed citations

Kidger, Andrew M., Joanne M. Munck, Harpreet K. Saini, et al.. (2019). Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2. Molecular Cancer Therapeutics. 19(2). 525–539. 17 indexed citations

O’Reilly, Marc, Anne Cleasby, Thomas G. Davies, et al.. (2019). Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design. Drug Discovery Today. 24(5). 1081–1086. 67 indexed citations

Lebraud, Honorine, Olga Surova, Aurélie Courtin, et al.. (2018). Quantitation of ERK1/2 inhibitor cellular target occupancies with a reversible slow off-rate probe. Chemical Science. 9(45). 8608–8618. 10 indexed citations

Wright, David J., Marc O’Reilly, & Dominic Tisi. (2017). Engineering and purification of a thermostable, high-yield, variant of PfCRT, the Plasmodium falciparum chloroquine resistance transporter. Protein Expression and Purification. 141. 7–18. 5 indexed citations

Lebraud, Honorine, et al.. (2016). In-gel activity-based protein profiling of a clickable covalent ERK1/2 inhibitor. Molecular BioSystems. 12(9). 2867–2874. 18 indexed citations

Mortenson, Paul N., Valério Berdini, & Marc O’Reilly. (2014). Fragment-Based Approaches to the Discovery of Kinase Inhibitors. Methods in enzymology on CD-ROM/Methods in enzymology. 548. 69–92. 14 indexed citations

Parnell, K. Mark, Jason M. Foulks, Rebecca N. Nix, et al.. (2013). Pharmacologic Activation of PKM2 Slows Lung Tumor Xenograft Growth. Molecular Cancer Therapeutics. 12(8). 1453–1460. 55 indexed citations

10.

Chaneton, Barbara, Petra Hillmann, Liang Zheng, et al.. (2012). Serine is a natural ligand and allosteric activator of pyruvate kinase M2. Nature. 491(7424). 458–462. 497 indexed citations breakdown →

11.

Day, Philip J., Anne Cleasby, Ian J. Tickle, et al.. (2009). Crystal structure of human CDK4 in complex with a D-type cyclin. Proceedings of the National Academy of Sciences. 106(11). 4166–4170. 176 indexed citations

12.

O’Reilly, Marc, M. Vinković, Andrew Sharff, & Harren Jhoti. (2006). High throughput protein crystallography: Developments in crystallisation, data collection and data processing. Drug Discovery Today Technologies. 3(4). 451–456. 4 indexed citations

13.

Gill, Adrian L., Martyn Frederickson, Anne Cleasby, et al.. (2004). Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation. Journal of Medicinal Chemistry. 48(2). 414–426. 146 indexed citations

14.

Wyatt, Paul G., Valério Berdini, Maria G. Carr, et al.. (2004). 117 Identification of novel cyclin dependent kinase 1/2 inhibitors using fragment based high-throughput X-ray crystallography and structure based drug design. European Journal of Cancer Supplements. 2(8). 38–38. 1 indexed citations

15.

O’Reilly, Marc, et al.. (2000). How the multifunctional yeast Rap1p discriminates between DNA target sites: a crystallographic analysis 1 1Edited by T. R. Richmond. Journal of Molecular Biology. 303(5). 693–707. 39 indexed citations

16.

O’Reilly, Marc, Sarah A. Teichmann, & Daniela Rhodes. (1999). Telomerases. Current Opinion in Structural Biology. 9(1). 56–65. 49 indexed citations

17.

O’Reilly, Marc, Kimberly A. Watson, & L.N. Johnson. (1999). The Crystal Structure of the Escherichia coli Maltodextrin Phosphorylase−Acarbose Complex^,. Biochemistry. 38(17). 5337–5345. 24 indexed citations

18.

O’Reilly, Marc, Kimberly A. Watson, Reinhard Schinzel, D. Palm, & L.N. Johnson. (1997). Oligosaccharide substrate binding in Escherichia coli maltodextrin phosphorylase. Nature Structural & Molecular Biology. 4(5). 405–412. 53 indexed citations

19.

Johnson, L.N. & Marc O’Reilly. (1996). Control by phosphorylation. Current Opinion in Structural Biology. 6(6). 762–769. 91 indexed citations

20.

O’Reilly, Marc, Andrew G. Geiser, Leslie A. Bruggeman, et al.. (1992). Identification of an activating transcription factor (ATF) binding site in the human transforming growth factor-beta 2 promoter.. Journal of Biological Chemistry. 267(28). 19938–19943. 48 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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