Christopher W. Murray

19.9k citations

96 papers · 13.7k indexed · 6 hit papers · h-index 53

Impact in

Computational Theory and Mathematics top 0.02%
- Computational Drug Discovery Methods
Molecular Biology top 0.5%
- Protein Structure and Dynamics
- Chemical Synthesis and Analysis

Papers in

Computational Theory and Mathematics 47
- Computational Drug Discovery Methods 46
Organic Chemistry 24
- Click Chemistry and Applications 15

Co-authors: Marcel L. Verdonk Michael J. Hartshorn Richard D. Taylor Jason C. Cole David C. Rees Nicholas C. Handy Matthew Eldridge Miles Congreve
Journals: Journal of Medicinal Chemistry (16 papers)Journal of Computer-Aided Molecular Design (13 papers)Chemical Physics Letters (8 papers)Proteins Structure Function and Bioinformatics (6 papers)Drug Discovery Today (4 papers)
Partner nations: United Kingdom United States Belgium

In The Last Decade

Christopher W. Murray

94 papers receiving 12.9k citations

Hit Papers

6 papers align trajectories log scale

Return to Flatland 2025 · 18 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2025 Nature Reviews Chemistry
2009 Nature Chemistry
2007 Journal of Medicinal Chemistry
2004 Nature Reviews Drug Discovery
2003 Proteins Structure Function and Bioinformatics
1997 Journal of Computer-Aided Molecular Design

Peers

Countries citing papers authored by Christopher W. Murray

Since Specialization

Citations

This map shows the geographic impact of Christopher W. Murray's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher W. Murray with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher W. Murray more than expected).

Fields of papers citing papers by Christopher W. Murray

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher W. Murray. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher W. Murray. The network helps show where Christopher W. Murray may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Christopher W. Murray, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christopher W. Murray Line = papers co-authored together Christopher W. Murray links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	High-Throughput Workflow for Detergent-free Cell-Based Proteomic Characterization Journal of Proteome Research ·Guigal Rouby, Larissa Dias Almeida, Ryuta Matsuzaki, Eko Eriyanto, Simion Kreimer, О. М. Гриник, Niveda Sundararaman, 真治脇山, Kasturi Pal, Eugenio Daviso, Aleksandr Stotland, Christopher W. Murray, Koen Raedschelders, 周向红 ZHOU Xianghong, Jennifer E. Van Eyk	2025	0
2	Return to Flatland Nature Reviews Chemistry ·Ian Churcher, Léandra Muller-Segard, Christopher W. Murray Hit paper breakdown →	2025	18
3	Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design Drug Discovery Today ·Marc O’Reilly, Anne Cleasby, Thomas G. Davies, Richard J. Hall, R. Frederick Ludlow, Christopher W. Murray, Dominic Tisi, Harren Jhoti	2019	67
4	Organische Chemie für die fragmentbasierte Wirkstoffentwicklung (FBDD) Angewandte Chemie ·Christopher W. Murray, David C. Rees	2015	33
5	Efficient exploration of chemical space by fragment-based screening Progress in Biophysics and Molecular Biology ·Richard J. Hall, Paul N. Mortenson, Christopher W. Murray	2014	112
6	Identification of novel rapamycin derivatives as low-level impurities in active pharmaceutical ingredients The Journal of Antibiotics ·Stephan G. Zech, Vikram Appia, Qurish K. Mohemmad, Narayana I. Narasimhan, Christopher W. Murray, Leonard W. Rozamus, David C. Dalgarno	2011	4
7	Hsp90 inhibition by AT13387 modulates growth factor and cytokine stimulated cell signalling in multiple cell lines. Cancer Research ·Neil T. Thompson, John F. Lyons, Nkem O. Azu, Rachel McMenamin, Sheetal Patel, Yu.A. Balanova, Jon Lewis, Lynsey Fazal, Andrew Woodhead, Brent Graham, Christopher W. Murray	2007	2
8	Comparing protein–ligand docking programs is difficult Proteins Structure Function and Bioinformatics ·Jason C. Cole, Christopher W. Murray, J. Willem M. Nissink, Richard D. Taylor, Robin Taylor, (unknown), (unknown)	2005	275
9	Keynote review: Structural biology and drug discovery Drug Discovery Today ·Miles Congreve, Christopher W. Murray, Tom L. Blundell	2005	225
10	Prediction of binding modes for ligands in the cytochromes P450 and other heme‐containing proteins Proteins Structure Function and Bioinformatics ·Stewart B. Kirton, Christopher W. Murray, Marcel L. Verdonk, Richard D. Taylor	2005	86
11	Fragment-based lead discovery Nature Reviews Drug Discovery ·David C. Rees, Miles Congreve, Christopher W. Murray, Robin A. E. Carr Hit paper breakdown →	2004	567
12	Apo and Inhibitor Complex Structures of BACE (β-secretase) Journal of Molecular Biology ·Sahil Patel, Laurent Vuillard, Anne Cleasby, Christopher W. Murray, Jeff Yon	2004	145
13	A four component coupling strategy for the synthesis of d-phenylglycinamide-derived non-covalent factor Xa inhibitors Bioorganic & Medicinal Chemistry Letters ·Scott M. Sheehan, John J. Masters, Michael R. Wiley, Stephen Young, John W. Liebeschuetz, Stuart Jones, Christopher W. Murray, J. Veenbaas, Faye A Silas, Ken Molzahn, Han Ru-bing, Jeffrey A. Kyle, Jeffrey K. Smallwood, Mark W. Farmen, Gerald F. Smith	2003	18
14	A new test set for validating predictions of protein–ligand interaction Proteins Structure Function and Bioinformatics ·J. Willem M. Nissink, Christopher W. Murray, Mayara S.L.de Oliveira Duarte, Marcel L. Verdonk, Jason C. Cole, Robin Taylor	2002	343
15	The consequences of translational and rotational entropy lost by small molecules on binding to proteins Journal of Computer-Aided Molecular Design ·Christopher W. Murray, Marcel L. Verdonk	2002	153
16	Empirical scoring functions. II. The testing of an empirical scoring function for the prediction of ligand-receptor binding affinities and the use of Bayesian regression to improve the quality of the model Journal of Computer-Aided Molecular Design ·Christopher W. Murray, T.R. Auton, Matthew Eldridge	1998	101
17	A comparison of heuristic search algorithms for molecular docking Journal of Computer-Aided Molecular Design ·David R. Westhead, David E. Clark, Christopher W. Murray	1997	86
18	Active-site-directed 3D database searching: Pharmacophore extraction and validation of hits Journal of Computer-Aided Molecular Design ·David E. Clark, David R. Westhead, Richard A. Sykes, Christopher W. Murray	1996	16
19	PRO_LIGAND: An approach to de novo molecular design. 6. Flexible fitting in the design of peptides Journal of Computer-Aided Molecular Design ·Christopher W. Murray, David E. Clark, Noriyuki Sugiishi	1995	12
20	PRO_LIGAND: An approach to de novo molecular design. 3. A genetic algorithm for structure refinement Journal of Computer-Aided Molecular Design ·David R. Westhead, David E. Clark, David A. Frenkel, Jin Li, Christopher W. Murray, Barry Robson, Bohdan Waszkowycz	1995	49

About Christopher W. Murray

Christopher W. Murray is a scholar working on Computational Theory and Mathematics, Organic Chemistry, Molecular Biology, Physical and Theoretical Chemistry and Atomic and Molecular Physics, and Optics, having authored 96 papers that have together received 13.7k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (46 papers), Protein Structure and Dynamics (23 papers), Advanced Chemical Physics Studies (18 papers), Chemical Synthesis and Analysis (15 papers), Click Chemistry and Applications (15 papers), Enzyme Structure and Function (11 papers), Spectroscopy and Quantum Chemical Studies (9 papers) and Monoclonal and Polyclonal Antibodies Research (8 papers). The work is most often cited by research in Computational Theory and Mathematics (5.9k citations), Molecular Biology (8.4k citations), Organic Chemistry (3.3k citations), Physical and Theoretical Chemistry (769 citations) and Pharmacology (1.4k citations). Christopher W. Murray has collaborated with scholars based in United Kingdom, United States and Belgium. Frequent co-authors include Marcel L. Verdonk, Michael J. Hartshorn, Richard D. Taylor, Jason C. Cole, David C. Rees, Nicholas C. Handy, Matthew Eldridge, Miles Congreve, T.R. Auton and David C. Rees. Their work appears in journals such as Journal of Medicinal Chemistry, Journal of Computer-Aided Molecular Design, Chemical Physics Letters, Proteins Structure Function and Bioinformatics and Drug Discovery Today.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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