David R. Brittelli

2.2k total citations · 1 hit paper
26 papers, 1.6k citations indexed

About

David R. Brittelli is a scholar working on Organic Chemistry, Molecular Biology and Oncology. According to data from OpenAlex, David R. Brittelli has authored 26 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Organic Chemistry, 9 papers in Molecular Biology and 5 papers in Oncology. Recurrent topics in David R. Brittelli's work include Synthesis and biological activity (4 papers), Chemical Synthesis and Analysis (4 papers) and Click Chemistry and Applications (3 papers). David R. Brittelli is often cited by papers focused on Synthesis and biological activity (4 papers), Chemical Synthesis and Analysis (4 papers) and Click Chemistry and Applications (3 papers). David R. Brittelli collaborates with scholars based in United States, China and India. David R. Brittelli's co-authors include Sarah L. Heald, Ingo Muegge, Walter A. Gregory, Barry M. Trost, Mark A. Wuonola, George A. Boswell, Martin Forbes, Andrew Slee, Charles R. Frihart and G. Michael Bright and has published in prestigious journals such as Journal of the American Chemical Society, Cancer Research and Journal of Medicinal Chemistry.

In The Last Decade

David R. Brittelli

26 papers receiving 1.6k citations

Hit Papers

Simple Selection Criteria for Drug-like Chemical Matter 2001 2026 2009 2017 2001 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Simple Selection Criteria for Drug-like Chemical Matter
    2001 924 citations Ingo Muegge, Sarah L. Heald et al. Journal of Medicinal Chemistry profile →

Peers

David R. Brittelli
Edmund L. Ellsworth United States
Diego Monti Italy
Vithal M. Kulkarni India
Alka Kurup United States
Yvette M. Fobian United States
Zongru Guo China
Martin Schlitzer Germany
José N. Domínguez Venezuela
John Proudfoot United States
Gordon Beck United Kingdom
Edmund L. Ellsworth United States
David R. Brittelli
Citations per year, relative to David R. Brittelli David R. Brittelli (= 1×) peers Edmund L. Ellsworth

Countries citing papers authored by David R. Brittelli

Since Specialization
Citations

This map shows the geographic impact of David R. Brittelli's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David R. Brittelli with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David R. Brittelli more than expected).

Fields of papers citing papers by David R. Brittelli

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David R. Brittelli. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David R. Brittelli. The network helps show where David R. Brittelli may publish in the future.

Co-authorship network of co-authors of David R. Brittelli

This figure shows the co-authorship network connecting the top 25 collaborators of David R. Brittelli. A scholar is included among the top collaborators of David R. Brittelli based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David R. Brittelli. David R. Brittelli is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Gordon, Michael S., et al.. (2010). 400 Phase I study of JI-101, a novel oral tyrosine kinase inhibitor that selectively targets EphB4, VEGFR2, and PDGFRβ. European Journal of Cancer Supplements. 8(7). 127–127. 2 indexed citations
2.
Velleca, Mark, Sunil Sharma, Michael S. Gordon, et al.. (2010). Abstract 17: Preclinical and phase 1 trial results of JI-101, a novel, oral tyrosine kinase inhibitor that selectively targets VEGFR2, EphB4, and PDGFRβ. Cancer Research. 70(8_Supplement). 17–17. 3 indexed citations
3.
Mitchell, Scott A., Peter Blomgren, James W. Darrow, et al.. (2009). Imidazo[1,2-a]pyrazine diaryl ureas: Inhibitors of the receptor tyrosine kinase EphB4. Bioorganic & Medicinal Chemistry Letters. 19(24). 6991–6995. 28 indexed citations
4.
Muegge, Ingo, Sarah L. Heald, & David R. Brittelli. (2001). Simple Selection Criteria for Drug-like Chemical Matter. Journal of Medicinal Chemistry. 44(12). 1841–1846. 924 indexed citations breakdown →
5.
Dumas, Jacques, David R. Brittelli, Jinshan Chen, et al.. (1999). Synthesis and structure activity relationships of novel small molecule cathepsin D inhibitors. Bioorganic & Medicinal Chemistry Letters. 9(17). 2531–2536. 82 indexed citations
6.
Chen, Jinshan, Brian R. Dixon, Jacques Dumas, & David R. Brittelli. (1999). Protocols for amide high-speed analoging. Preparation of novel, small molecule cathepsin D inhibitors. Tetrahedron Letters. 40(52). 9195–9199. 8 indexed citations
7.
Fevig, John M., Matthew M. Abelman, David R. Brittelli, et al.. (1996). Design and synthesis of ring-constrained boropeptide thrombin inhibitors. Bioorganic & Medicinal Chemistry Letters. 6(3). 295–300. 30 indexed citations
8.
Brittelli, David R., Frank D. Marsh, Walter A. Gregory, et al.. (1992). Antibacterials. Synthesis and structure-activity studies of 3-aryl-2-oxooxazolidines. 4. Multiply-substituted aryl derivatives. Journal of Medicinal Chemistry. 35(6). 1156–1165. 79 indexed citations
9.
Gregory, Walter A., David R. Brittelli, Hollis S. Kezar, et al.. (1991). ChemInform Abstract: Antibacterials. Synthesis and Structure‐Activity Studies of 3‐Aryl‐2‐ oxooxazolidines. Part 2. The “A” Group.. ChemInform. 22(8). 3 indexed citations
10.
Gregory, Walter A., et al.. (1990). Antibacterials. Synthesis and structure-activity studies of 3-aryl-2-oxooxazolidines. 2. The "A" group. Journal of Medicinal Chemistry. 33(9). 2569–2578. 68 indexed citations
11.
Gregory, Walter A., David R. Brittelli, Mark A. Wuonola, et al.. (1989). Antibacterials. Synthesis and structure-activity studies of 3-aryl-2-oxooxazolidines. 1. The B group. Journal of Medicinal Chemistry. 32(8). 1673–1681. 141 indexed citations
12.
Brittelli, David R. & David F. Eaton. (1989). Twisted internal charge transfer emission in B,B‐bis(mesityl) pyrroloboranes. Journal of Physical Organic Chemistry. 2(1). 89–92. 5 indexed citations
13.
Brittelli, David R.. (1985). A study of the reaction of 2-haloacyl halides with trialkyl phosphites. Synthesis of 2-substituted acyl phosphonates. The Journal of Organic Chemistry. 50(11). 1845–1847. 13 indexed citations
14.
Burton, Donald J., Douglas G. Naae, Richard M. Flynn, Bruce E. Smart, & David R. Brittelli. (1983). Phosphine- and phosphite-mediated difluorocarbene exchange reactions of (bromodifluoromethyl)phosphonium salts. Evidence for facile dissociation of (difluoromethylene)triphenylphosphorane. The Journal of Organic Chemistry. 48(20). 3616–3618. 31 indexed citations
15.
Brittelli, David R. & George A. Boswell. (1981). New furoxan chemistry. 1. Synthesis of diacylfuroxans by reaction of ethynyl acetates with nitrosyl fluoride nitrosonium tetrafluoroborate. The Journal of Organic Chemistry. 46(2). 312–315. 16 indexed citations
16.
Brittelli, David R.. (1981). Phosphite-mediated in situ carboxyvinylation: a new general acrylic acid synthesis. The Journal of Organic Chemistry. 46(12). 2514–2520. 46 indexed citations
17.
Brittelli, David R. & George A. Boswell. (1981). ChemInform Abstract: NEW FUROXAN CHEMISTRY. 2. CHEMISTRY OF ACYL NITRILE OXIDES GENERATED IN SITU BY THERMOLYSIS OF DIACYLFUROXANS. Chemischer Informationsdienst. 12(26). 5 indexed citations
18.
Trost, Barry M., G. Michael Bright, Charles R. Frihart, & David R. Brittelli. (1971). Perturbed [12]annulenes. Synthesis of pyracylenes. Journal of the American Chemical Society. 93(3). 737–745. 82 indexed citations
19.
Trost, Barry M. & David R. Brittelli. (1967). 1,2-dibromopyracylene: A new aromatic system. Tetrahedron Letters. 8(2). 119–122. 1 indexed citations
20.
Trost, Barry M. & David R. Brittelli. (1967). The halogenation of acenaphthene derivatives. The Journal of Organic Chemistry. 32(8). 2620–2621. 14 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Edmund L. Ellsworth Breakdown of academic impact, for papers by Diego Monti Breakdown of academic impact, for papers by Vithal M. Kulkarni Breakdown of academic impact, for papers by Alka Kurup Breakdown of academic impact, for papers by Yvette M. Fobian Breakdown of academic impact, for papers by Zongru Guo Breakdown of academic impact, for papers by Martin Schlitzer Breakdown of academic impact, for papers by José N. Domínguez Breakdown of academic impact, for papers by John Proudfoot Breakdown of academic impact, for papers by Gordon Beck
Rankless by CCL
2026