David Leys

11.2k total citations
190 papers, 8.7k citations indexed

About

David Leys is a scholar working on Molecular Biology, Pharmacology and Biochemistry. According to data from OpenAlex, David Leys has authored 190 papers receiving a total of 8.7k indexed citations (citations by other indexed papers that have themselves been cited), including 140 papers in Molecular Biology, 34 papers in Pharmacology and 33 papers in Biochemistry. Recurrent topics in David Leys's work include Pharmacogenetics and Drug Metabolism (34 papers), Microbial Metabolic Engineering and Bioproduction (28 papers) and Enzyme Structure and Function (27 papers). David Leys is often cited by papers focused on Pharmacogenetics and Drug Metabolism (34 papers), Microbial Metabolic Engineering and Bioproduction (28 papers) and Enzyme Structure and Function (27 papers). David Leys collaborates with scholars based in United Kingdom, United States and France. David Leys's co-authors include Nigel S. Scrutton, Andrew W. Munro, Colin Levy, Kirsty J. McLean, Mark S. Dunstan, Karl Fisher, Stephen E. J. Rigby, K.A.P. Payne, Helen S. Toogood and Sam Hay and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

David Leys

186 papers receiving 8.6k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
David Leys United Kingdom 58 5.6k 1.6k 1.0k 887 832 190 8.7k
Andrew W. Munro United Kingdom 56 5.6k 1.0× 4.2k 2.6× 1.9k 1.9× 717 0.8× 986 1.2× 219 9.3k
David P. Ballou United States 57 6.0k 1.1× 968 0.6× 1.9k 1.9× 742 0.8× 561 0.7× 202 10.3k
Nigel S. Scrutton United Kingdom 63 10.7k 1.9× 1.1k 0.7× 1.8k 1.8× 1.7k 1.9× 361 0.4× 460 15.9k
Rita Bernhardt Germany 51 5.9k 1.1× 4.3k 2.7× 966 0.9× 384 0.4× 622 0.7× 292 10.5k
Peter Macheroux Austria 49 4.9k 0.9× 383 0.2× 518 0.5× 1.1k 1.3× 331 0.4× 205 7.1k
Michelle C. Y. Chang United States 34 4.7k 0.9× 380 0.2× 852 0.8× 765 0.9× 252 0.3× 70 8.0k
Andrea Mattevi Italy 69 10.0k 1.8× 529 0.3× 812 0.8× 2.3k 2.6× 345 0.4× 236 15.4k
Yoshitsugu Shiro Japan 51 4.6k 0.8× 1.4k 0.9× 1.8k 1.8× 634 0.7× 496 0.6× 232 8.4k
Atta‐ur Rahman Pakistan 56 5.9k 1.1× 2.8k 1.8× 474 0.5× 4.5k 5.0× 881 1.1× 738 16.2k
Willem J. H. van Berkel Netherlands 60 7.4k 1.3× 476 0.3× 1.0k 1.0× 1.1k 1.3× 145 0.2× 314 12.7k

Countries citing papers authored by David Leys

Since Specialization
Citations

This map shows the geographic impact of David Leys's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Leys with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Leys more than expected).

Fields of papers citing papers by David Leys

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Leys. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Leys. The network helps show where David Leys may publish in the future.

Co-authorship network of co-authors of David Leys

This figure shows the co-authorship network connecting the top 25 collaborators of David Leys. A scholar is included among the top collaborators of David Leys based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Leys. David Leys is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Yu, Yuqi, Linus O. Johannissen, Michiyo Sakuma, et al.. (2024). SignatureFinder enables sequence mining to identify cobalamin‐dependent photoreceptor proteins. FEBS Journal. 292(3). 635–652.
2.
Zhang, Shaowei, Michiyo Sakuma, Girdhar Singh Deora, et al.. (2019). A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Communications Biology. 2(1). 271–271. 44 indexed citations
3.
Girvan, Hazel M., Kirsty J. McLean, David R. Nelson, et al.. (2018). Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus. Journal of Inorganic Biochemistry. 188. 18–28. 22 indexed citations
4.
Acevedo‐Rocha, Carlos G., Richard Lonsdale, Aitao Li, et al.. (2018). P450-Catalyzed Regio- and Diastereoselective Steroid Hydroxylation: Efficient Directed Evolution Enabled by Mutability Landscaping. ACS Catalysis. 8(4). 3395–3410. 136 indexed citations
5.
Weise, Nicholas J., Mark S. Dunstan, Michael A. R. Hollas, et al.. (2017). Adenylation Activity of Carboxylic Acid Reductases Enables the Synthesis of Amides. Angewandte Chemie International Edition. 56(46). 14498–14501. 81 indexed citations
6.
Payer, Stefan E., Stephen Marshall, Xiang Sheng, et al.. (2017). Regioselective para‐Carboxylation of Catechols with a Prenylated Flavin Dependent Decarboxylase. Angewandte Chemie International Edition. 56(44). 13893–13897. 64 indexed citations
7.
Weise, Nicholas J., Mark S. Dunstan, Michael A. R. Hollas, et al.. (2017). Adenylation Activity of Carboxylic Acid Reductases Enables the Synthesis of Amides. Angewandte Chemie. 129(46). 14690–14693. 28 indexed citations
8.
Kavanagh, Madeline E., Max D. Driscoll, Kirsty J. McLean, et al.. (2016). Structural characterization of CYP144A1 – a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis. Scientific Reports. 6(1). 26628–26628. 8 indexed citations
9.
10.
McLean, Kirsty J., Marcus Hans, Wibo B. van Scheppingen, et al.. (2015). Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum. Proceedings of the National Academy of Sciences. 112(9). 2847–2852. 97 indexed citations
11.
Menon, Binuraj R. K., Karl Fisher, Stephen E. J. Rigby, Nigel S. Scrutton, & David Leys. (2014). A Conformational Sampling Model for Radical Catalysis in Pyridoxal Phosphate- and Cobalamin-dependent Enzymes. Journal of Biological Chemistry. 289(49). 34161–34174. 2 indexed citations
12.
Dunstan, Mark S., et al.. (2013). Research article: The transcriptional regulator CprK detects chlorination by combining direct and indirect readout mechanisms. Philosophical Transactions of the Royal Society B Biological Sciences. 368(1616). 1–6. 94 indexed citations
13.
Khara, B., Colin Levy, David Mansell, et al.. (2013). Production of Propane and Other Short‐Chain Alkanes by Structure‐Based Engineering of Ligand Specificity in Aldehyde‐Deformylating Oxygenase. ChemBioChem. 14(10). 1204–1208. 82 indexed citations
14.
Nolan, Karen A., et al.. (2011). In Silico Screening Reveals Structurally Diverse, Nanomolar Inhibitors of NQO2 That Are Functionally Active in Cells and Can Modulate NF-κB Signaling. Molecular Cancer Therapeutics. 11(1). 194–203. 17 indexed citations
15.
Dixon, Neil, John Duncan, Torsten H. Geerlings, et al.. (2010). Reengineering orthogonally selective riboswitches. Proceedings of the National Academy of Sciences. 107(7). 2830–2835. 131 indexed citations
16.
Wolthers, Kirsten R., Colin Levy, Nigel S. Scrutton, & David Leys. (2010). Large-scale Domain Dynamics and Adenosylcobalamin Reorientation Orchestrate Radical Catalysis in Ornithine 4,5-Aminomutase. Journal of Biological Chemistry. 285(18). 13942–13950. 42 indexed citations
17.
Levy, Colin, Derren J. Heyes, Michael Joyce, et al.. (2008). Molecular basis of halorespiration control by CprK, a CRP‐FNR type transcriptional regulator. Molecular Microbiology. 70(1). 151–167. 39 indexed citations
18.
McLean, Kirsty J., Paul Carroll, Daniel Lewis, et al.. (2008). Characterization of Active Site Structure in CYP121: A Cytochrome P450 Essential for Viability of Mycobacterium Tuberculosis H37Rv*. Journal of Biological Chemistry. 283(48). 33406–33416. 107 indexed citations
19.
Leys, David, et al.. (2007). P450 systems in Mycobacterium tuberculosis: structure, function and drug targeting. Drug Metabolism Reviews. 39. 4–5. 1 indexed citations
20.
Joyce, Michael, Colin Levy, Tzanko Doukov, et al.. (2006). CprK Crystal Structures Reveal Mechanism for Transcriptional Control of Halorespiration. Journal of Biological Chemistry. 281(38). 28318–28325. 27 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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