Bharat B. Aggarwal

139.0k total citations · 43 hit papers
574 papers, 104.9k citations indexed

About

Bharat B. Aggarwal is a scholar working on Molecular Biology, Cancer Research and Immunology. According to data from OpenAlex, Bharat B. Aggarwal has authored 574 papers receiving a total of 104.9k indexed citations (citations by other indexed papers that have themselves been cited), including 325 papers in Molecular Biology, 194 papers in Cancer Research and 141 papers in Immunology. Recurrent topics in Bharat B. Aggarwal's work include NF-κB Signaling Pathways (176 papers), Curcumin's Biomedical Applications (107 papers) and Natural product bioactivities and synthesis (99 papers). Bharat B. Aggarwal is often cited by papers focused on NF-κB Signaling Pathways (176 papers), Curcumin's Biomedical Applications (107 papers) and Natural product bioactivities and synthesis (99 papers). Bharat B. Aggarwal collaborates with scholars based in United States, India and Germany. Bharat B. Aggarwal's co-authors include Ajaikumar B. Kunnumakkara, Subash C. Gupta, Shishir Shishodia, Bokyung Sung, Preetha Anand, Sahdeo Prasad, Gautam Sethi, Kuzhuvelil B. Harikumar, Madan M. Chaturvedi and Yasunari Takada and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Bharat B. Aggarwal

564 papers receiving 101.2k citations

Hit Papers

Bioavailability of Curcumin: Problems ... 1984 2026 1998 2012 2007 2010 2003 2003 2007 1000 2.0k 3.0k 4.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Bioavailability of Curcumin: Problems and Promises
    2007 4.4k citations Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal et al. profile →
  2. Oxidative stress, inflammation, and cancer: How are they linked?
    2010 4.2k citations Simone Reuter, Subash C. Gupta et al. Free Radical Biology and Medicine profile →
  3. Anticancer potential of curcumin: preclinical and clinical studies.
    2003 2.2k citations Bharat B. Aggarwal et al. profile →
  4. Signalling pathways of the TNF superfamily: a double-edged sword
    2003 2.2k citations Bharat B. Aggarwal profile →
  5. Curcumin as “Curecumin”: From kitchen to clinic
    2007 1.8k citations Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal et al. Biochemical Pharmacology profile →
  6. Cancer is a Preventable Disease that Requires Major Lifestyle Changes
    2008 1.6k citations Kuzhuvelil B. Harikumar, Bokyung Sung et al. profile →
  7. Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases
    2008 1.5k citations Bharat B. Aggarwal, Kuzhuvelil B. Harikumar profile →
  8. Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials
    2012 1.5k citations Subash C. Gupta, Bharat B. Aggarwal et al. profile →
  9. Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin
    1984 1.4k citations Bharat B. Aggarwal et al. profile →
  10. Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro
    1985 1.4k citations Bharat B. Aggarwal et al. profile →
  11. Molecular targets of dietary agents for prevention and therapy of cancer
    2006 1.4k citations Bharat B. Aggarwal et al. Biochemical Pharmacology profile →
  12. Nuclear factor-κB
    2004 1.4k citations Bharat B. Aggarwal profile →
  13. CURCUMIN: THE INDIAN SOLID GOLD
    2007 1.3k citations Bharat B. Aggarwal et al. profile →
  14. Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane)
    1995 1.2k citations Bharat B. Aggarwal et al. Journal of Biological Chemistry profile →
  15. Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.
    2004 1.2k citations Bharat B. Aggarwal, Yasunari Takada et al. profile →
  16. Inflammation and cancer: How hot is the link?
    2006 1.1k citations Bharat B. Aggarwal, Manoj K. Pandey et al. Biochemical Pharmacology profile →
  17. Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer
    2008 1.1k citations Bharat B. Aggarwal, Ajaikumar B. Kunnumakkara et al. Clinical Cancer Research profile →
  18. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B.
    1996 1.0k citations Bharat B. Aggarwal et al. profile →
  19. Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature
    2008 990 citations Ajaikumar B. Kunnumakkara, Kuzhuvelil B. Harikumar et al. Biochemical Pharmacology profile →
  20. Curcumin and cancer: An “old-age” disease with an “age-old” solution
    2008 914 citations Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal et al. profile →
  21. Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets
    2008 901 citations Bharat B. Aggarwal, Bokyung Sung profile →
  22. Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins
    2008 877 citations Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal et al. profile →
  23. Recent Developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin: the Golden Pigment from Golden Spice
    2014 835 citations Sahdeo Prasad, Bharat B. Aggarwal et al. profile →
  24. Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases
    2016 795 citations Ajaikumar B. Kunnumakkara, Sahdeo Prasad et al. profile →
  25. Characterization of receptors for human tumour necrosis factor and their regulation by γ-interferon
    1985 781 citations Bharat B. Aggarwal et al. profile →
  26. Human tumor necrosis factor. Production, purification, and characterization.
    1985 777 citations Bharat B. Aggarwal et al. Journal of Biological Chemistry profile →
  27. Resveratrol Suppresses TNF-Induced Activation of Nuclear Transcription Factors NF-κB, Activator Protein-1, and Apoptosis: Potential Role of Reactive Oxygen Intermediates and Lipid Peroxidation
    2000 716 citations Sunil K. Manna, Bharat B. Aggarwal et al. profile →
  28. Discovery of curcumin, a component of golden spice, and its miraculous biological activities
    2011 673 citations Subash C. Gupta, Bharat B. Aggarwal et al. profile →
  29. Curcumin, a component of golden spice: From bedside to bench and back
    2014 637 citations Sahdeo Prasad, Bharat B. Aggarwal et al. profile →
  30. Inhibiting NF-κB activation by small molecules as a therapeutic strategy
    2010 633 citations Subash C. Gupta, Simone Reuter et al. profile →
  31. Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journey
    2011 629 citations Bharat B. Aggarwal, Subash C. Gupta et al. profile →
  32. Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
    2010 622 citations Subash C. Gupta, Sahdeo Prasad et al. profile →
  33. Curcumin and Cancer Cells: How Many Ways Can Curry Kill Tumor Cells Selectively?
    2009 621 citations Jayaraj Ravindran, Sahdeo Prasad et al. profile →
  34. Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe
    2009 613 citations Bharat B. Aggarwal, Bokyung Sung et al. Clinical Cancer Research profile →
  35. Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy
    2011 604 citations Subash C. Gupta, Bharat B. Aggarwal et al. profile →
  36. Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor–κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis
    2003 596 citations Bharat B. Aggarwal et al. profile →
  37. Signal Transducer and Activator of Transcription‐3, Inflammation, and Cancer
    2009 578 citations Bharat B. Aggarwal, Ajaikumar B. Kunnumakkara et al. profile →
  38. Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism
    2007 562 citations Manoj K. Pandey, Bokyung Sung et al. profile →
  39. Multitargeting by curcumin as revealed by molecular interaction studies
    2011 522 citations Subash C. Gupta, Sahdeo Prasad et al. profile →
  40. Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity
    1984 514 citations Bharat B. Aggarwal et al. profile →
  41. Overexpression of Manganese Superoxide Dismutase Suppresses Tumor Necrosis Factor-induced Apoptosis and Activation of Nuclear Transcription Factor-κB and Activated Protein-1
    1998 507 citations Sunil K. Manna, Bharat B. Aggarwal et al. Journal of Biological Chemistry profile →
  42. Tocotrienols, the vitamin E of the 21st century: Its potential against cancer and other chronic diseases
    2010 439 citations Bharat B. Aggarwal, Ramaswamy Kannappan et al. Biochemical Pharmacology profile →
  43. Role of Turmeric and Curcumin in Prevention and Treatment of Chronic Diseases: Lessons Learned from Clinical Trials
    2023 115 citations Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Bharat B. Aggarwal United States 166 48.7k 26.3k 16.0k 14.7k 13.9k 574 104.9k
Amirhossein Sahebkar Iran 127 22.9k 0.5× 11.9k 0.5× 8.4k 0.5× 6.8k 0.5× 5.0k 0.4× 1.9k 69.4k
Gautam Sethi Singapore 125 26.2k 0.5× 3.3k 0.1× 4.5k 0.3× 9.1k 0.6× 8.7k 0.6× 615 48.2k
Masayuki Yamamoto Japan 169 85.7k 1.8× 987 0.0× 11.1k 0.7× 9.1k 0.6× 5.1k 0.4× 1.4k 119.9k
Carl Nathan United States 115 23.9k 0.5× 1.8k 0.1× 22.2k 1.4× 4.3k 0.3× 5.0k 0.4× 318 73.0k
Guido Kroemer France 228 128.2k 2.6× 1.2k 0.0× 51.4k 3.2× 28.9k 2.0× 45.9k 3.3× 1.4k 235.5k
Michael Karin United States 229 113.1k 2.3× 1.2k 0.0× 60.2k 3.8× 56.6k 3.8× 45.8k 3.3× 652 212.6k
Tim R. Mosmann United States 53 22.7k 0.5× 901 0.0× 20.7k 1.3× 3.5k 0.2× 9.4k 0.7× 124 75.3k
Douglas R. Green United States 178 80.9k 1.7× 689 0.0× 35.3k 2.2× 15.1k 1.0× 18.8k 1.4× 613 125.1k
Christopher J. Schofield United Kingdom 96 27.9k 0.6× 3.1k 0.1× 1.4k 0.1× 15.3k 1.0× 3.2k 0.2× 803 45.6k
Hasan Mukhtar United States 114 14.6k 0.3× 1.5k 0.1× 2.1k 0.1× 4.1k 0.3× 4.2k 0.3× 557 41.3k

Countries citing papers authored by Bharat B. Aggarwal

Since Specialization
Citations

This map shows the geographic impact of Bharat B. Aggarwal's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bharat B. Aggarwal with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bharat B. Aggarwal more than expected).

Fields of papers citing papers by Bharat B. Aggarwal

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bharat B. Aggarwal. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bharat B. Aggarwal. The network helps show where Bharat B. Aggarwal may publish in the future.

Co-authorship network of co-authors of Bharat B. Aggarwal

This figure shows the co-authorship network connecting the top 25 collaborators of Bharat B. Aggarwal. A scholar is included among the top collaborators of Bharat B. Aggarwal based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Bharat B. Aggarwal. Bharat B. Aggarwal is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Aggarwal, Bharat B., et al.. (2025). Comparative analysis of brain volumetric measurements between contrast-enhanced and non-contrast MRI images. Neuroscience Letters. 848. 138118–138118. 1 indexed citations
2.
3.
Buhrmann, Constanze, Bastian Popper, Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal, & Mehdi Shakibaei. (2019). Evidence That Calebin A, a Component of Curcuma Longa Suppresses NF-κB Mediated Proliferation, Invasion and Metastasis of Human Colorectal Cancer Induced by TNF-β (Lymphotoxin). Nutrients. 11(12). 2904–2904. 58 indexed citations
4.
Aggarwal, Bharat B., et al.. (2014). Correlation of blood culture and band cell ratio in neonatal septicaemia.. IOSR Journal of Dental and Medical Sciences. 13(3). 55–58. 1 indexed citations
5.
Gupta, Subash C., et al.. (2013). Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment. Clinical Cancer Research. 19(16). 4465–4476. 86 indexed citations
6.
Buhrmann, Constanze, Parviz Shayan, Bharat B. Aggarwal, & Mehdi Shakibaei. (2013). Evidence that TNF-β (lymphotoxin α) can activate the inflammatory environment in human chondrocytes. Arthritis Research & Therapy. 15(6). R202–R202. 56 indexed citations
7.
Prasad, Sahdeo, Vivek R. Yadav, Bokyung Sung, et al.. (2012). Ursolic Acid Inhibits Growth and Metastasis of Human Colorectal Cancer in an Orthotopic Nude Mouse Model by Targeting Multiple Cell Signaling Pathways: Chemosensitization with Capecitabine. Clinical Cancer Research. 18(18). 4942–4953. 152 indexed citations
8.
Heymach, John V., Terry J. Shackleford, Hai T. Tran, et al.. (2011). Effect of Low-Fat Diets on Plasma Levels of NF-κB–Regulated Inflammatory Cytokines and Angiogenic Factors in Men with Prostate Cancer. Cancer Prevention Research. 4(10). 1590–1598. 43 indexed citations
9.
Kunnumakkara, Ajaikumar B., Bokyung Sung, Jayaraj Ravindran, et al.. (2010). γ-Tocotrienol Inhibits Pancreatic Tumors and Sensitizes Them to Gemcitabine Treatment by Modulating the Inflammatory Microenvironment. Cancer Research. 70(21). 8695–8705. 107 indexed citations
10.
Reuter, Simone, Subash C. Gupta, Madan M. Chaturvedi, & Bharat B. Aggarwal. (2010). Oxidative stress, inflammation, and cancer: How are they linked?. Free Radical Biology and Medicine. 49(11). 1603–1616. 4200 indexed citations breakdown →
11.
Matsuo, Yoichi, Paul M. Campbell, Rolf A. Brekken, et al.. (2009). K-Ras Promotes Angiogenesis Mediated by Immortalized Human Pancreatic Epithelial Cells through Mitogen-Activated Protein Kinase Signaling Pathways. Molecular Cancer Research. 7(6). 799–808. 68 indexed citations
12.
Tong, Zhimin, Ajaikumar B. Kunnumakkara, Huamin Wang, et al.. (2008). Neutrophil Gelatinase–Associated Lipocalin: A Novel Suppressor of Invasion and Angiogenesis in Pancreatic Cancer. Cancer Research. 68(15). 6100–6108. 144 indexed citations
13.
Pandey, Manoj K., Bokyung Sung, Ajaikumar B. Kunnumakkara, et al.. (2008). Berberine Modifies Cysteine 179 of IκBα Kinase, Suppresses Nuclear Factor-κB–Regulated Antiapoptotic Gene Products, and Potentiates Apoptosis. Cancer Research. 68(13). 5370–5379. 159 indexed citations
14.
Sethi, Gautam, Kwang Seok Ahn, M. Chaturvedi, & Bharat B. Aggarwal. (2007). Epidermal growth factor (EGF) activates nuclear factor-κB through IκBα kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IκBα. Oncogene. 26(52). 7324–7332. 84 indexed citations
15.
Takada, Yasunari, Bokyung Sung, Gautam Sethi, Madan M. Chaturvedi, & Bharat B. Aggarwal. (2007). Evidence that genetic deletion of the TNF receptor p60 or p80 inhibits Fas mediated apoptosis in macrophages. Biochemical Pharmacology. 74(7). 1057–1064. 20 indexed citations
16.
Xia, Dianren, Young‐Ho Ahn, Gautam Sethi, et al.. (2006). Mitogen-activated Protein Kinase Kinase-4 Promotes Cell Survival by Decreasing PTEN Expression through an NFκB-dependent Pathway. Journal of Biological Chemistry. 282(6). 3507–3519. 84 indexed citations
17.
Ahn, Kwang Seok, Gautam Sethi, Abhinav K. Jain, Anil K. Jaiswal, & Bharat B. Aggarwal. (2006). Genetic Deletion of NAD(P)H:Quinone Oxidoreductase 1 Abrogates Activation of Nuclear Factor-κB, IκBα Kinase, c-Jun N-terminal Kinase, Akt, p38, and p44/42 Mitogen-activated Protein Kinases and Potentiates Apoptosis. Journal of Biological Chemistry. 281(29). 19798–19808. 119 indexed citations
18.
Malhotra, Usha, Walter N. Hittelman, Tsung Teh Wu, et al.. (2005). Association of activated NF-kB, altered cyclin D1 and poor outcome in esophageal adenocarcinoma. Cancer Research. 65. 548–548. 1 indexed citations
19.
Chainy, G.B.N., Sunil K. Manna, Madan M. Chaturvedi, & Bharat B. Aggarwal. (2000). Anethole blocks both early and late cellular responses transduced by tumor necrosis factor: effect on NF-κB, AP-1, JNK, MAPKK and apoptosis. Oncogene. 19(25). 2943–2950. 173 indexed citations
20.
Higuchi, Masahiro & Bharat B. Aggarwal. (1993). P80 form of the human tumor necrosis factor receptor is involved in DNA fragmentation. FEBS Letters. 331(3). 252–255. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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