David Needham

18.0k total citations · 4 hit papers
150 papers, 14.5k citations indexed

About

David Needham is a scholar working on Molecular Biology, Biomedical Engineering and Biomaterials. According to data from OpenAlex, David Needham has authored 150 papers receiving a total of 14.5k indexed citations (citations by other indexed papers that have themselves been cited), including 77 papers in Molecular Biology, 47 papers in Biomedical Engineering and 33 papers in Biomaterials. Recurrent topics in David Needham's work include Lipid Membrane Structure and Behavior (55 papers), Nanoparticle-Based Drug Delivery (30 papers) and Surfactants and Colloidal Systems (18 papers). David Needham is often cited by papers focused on Lipid Membrane Structure and Behavior (55 papers), Nanoparticle-Based Drug Delivery (30 papers) and Surfactants and Colloidal Systems (18 papers). David Needham collaborates with scholars based in United States, United Kingdom and Denmark. David Needham's co-authors include Thomas J. McIntosh, Mark W. Dewhirst, R.M. Hochmuth, Kevin C. Olbrich, W. Rawicz, Evan Evans, Rashmi S. Nunn, EA Evans, Gopal Anyarambhatla and Doncho V. Zhelev and has published in prestigious journals such as Nature, Science and Chemical Reviews.

In The Last Decade

David Needham

148 papers receiving 14.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Effect of Chain Length and Unsaturation on Elasticity of Lipid Bilayers

2000 1.5k citations W. Rawicz, Kevin C. Olbrich et al. Biophysical Journal profile →
Elastic deformation and failure of lipid bilayer membranes containing cholesterol

1990 706 citations David Needham et al. Biophysical Journal profile →
A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model.

2000 627 citations David Needham, Mark W. Dewhirst et al. profile →
Physical properties of surfactant bilayer membranes: thermal transitions, elasticity, rigidity, cohesion and colloidal interactions

1987 624 citations David Needham et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David Needham United States	62	7.8k	5.3k	3.7k	2.0k	1.6k	150	14.5k
Rumiana Dimova Germany	57	6.4k 0.8×	3.2k 0.6×	1.4k 0.4×	1.4k 0.7×	1.3k 0.8×	204	10.4k
Dan W. Urry United States	63	6.8k 0.9×	2.4k 0.5×	3.1k 0.8×	1.3k 0.6×	1.1k 0.7×	337	14.3k
Joachim O. Rädler Germany	57	6.8k 0.9×	3.4k 0.6×	1.7k 0.5×	1.5k 0.7×	1.1k 0.7×	192	12.2k
Daniel A. Hammer United States	71	6.6k 0.8×	5.4k 1.0×	3.1k 0.8×	2.1k 1.1×	3.3k 2.1×	279	21.0k
Patrick S. Stayton United States	77	8.8k 1.1×	4.7k 0.9×	4.8k 1.3×	788 0.4×	3.5k 2.1×	264	18.9k
Demetrios Papahadjopoulos United States	82	18.2k 2.3×	3.9k 0.7×	7.4k 2.0×	1.3k 0.7×	2.0k 1.2×	178	26.2k
Shuichi Takayama United States	75	4.7k 0.6×	14.8k 2.8×	1.7k 0.5×	799 0.4×	1.1k 0.7×	317	22.5k
Paul S. Cremer United States	77	7.8k 1.0×	5.8k 1.1×	1.8k 0.5×	6.3k 3.2×	2.7k 1.7×	171	20.7k
Milan Mrksich United States	84	12.0k 1.5×	11.7k 2.2×	2.6k 0.7×	2.2k 1.1×	2.3k 1.4×	266	27.8k
V. Adrian Parsegian United States	74	9.8k 1.2×	4.0k 0.8×	1.0k 0.3×	6.7k 3.4×	2.1k 1.3×	198	18.8k

Countries citing papers authored by David Needham

Since Specialization

Citations

This map shows the geographic impact of David Needham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Needham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Needham more than expected).

Fields of papers citing papers by David Needham

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Needham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Needham. The network helps show where David Needham may publish in the future.

Co-authorship network of co-authors of David Needham

This figure shows the co-authorship network connecting the top 25 collaborators of David Needham. A scholar is included among the top collaborators of David Needham based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Needham. David Needham is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Williams, Philip M., et al.. (2025). LDLR-targeted orlistat therapeutic nanoparticles: Peptide selection, assembly, characterization, and cell-uptake in breast cancer cell lines. International Journal of Pharmaceutics. 676. 125574–125574. 2 indexed citations

Needham, David, et al.. (2023). Low-Density Lipoprotein Pathway Is a Ubiquitous Metabolic Vulnerability in High Grade Glioma Amenable for Nanotherapeutic Delivery. Pharmaceutics. 15(2). 599–599. 4 indexed citations

Kutsch, Miriam, Linda Sistemich, Dulcemaria Hernandez, et al.. (2023). LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro. Proceedings of the National Academy of Sciences. 120(15). e2216028120–e2216028120. 37 indexed citations

Reddy, Gireesh B., David L. Kerr, Ivan Spasojević, et al.. (2020). Preclinical Testing of a Novel Niclosamide Stearate Prodrug Therapeutic (NSPT) Shows Efficacy Against Osteosarcoma. Molecular Cancer Therapeutics. 19(7). 1448–1461. 20 indexed citations

El-Houri, Rime, et al.. (2019). Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells. Journal of Visualized Experiments. 2 indexed citations

Munk, Merete B., et al.. (2018). Oleogelating properties of ethylcellulose in oil-in-water emulsions: The impact of emulsification methods studied by 13C MAS NMR, surface tension and micropipette manipulation studies. Food Hydrocolloids. 89. 700–706. 26 indexed citations

Duelund, Lars, et al.. (2016). Data for the size of cholesterol-fat micelles as a function of bile salt concentration and the physico-chemical properties of six liquid experimental pine-derived phytosterol formulations in a cholesterol-containing artificial intestine fluid. Data in Brief. 10. 478–481. 3 indexed citations

Manzoor, Ashley A., Lars H. Lindner, Chelsea D. Landon, et al.. (2012). Overcoming Limitations in Nanoparticle Drug Delivery: Triggered, Intravascular Release to Improve Drug Penetration into Tumors. Cancer Research. 72(21). 5566–5575. 375 indexed citations

Ponce, Ana M., Željko Vujašković, Fan Yuan, David Needham, & Mark W. Dewhirst. (2006). Hyperthermia mediated liposomal drug delivery. International Journal of Hyperthermia. 22(3). 205–213. 217 indexed citations

10.

Needham, David, et al.. (2006). Temperature-Triggered Nanotechnology for Chemotherapy: Rapid Release From Lysolipid Temperature-Sensitive Liposomes. TechConnect Briefs. 2(2006). 5–8. 1 indexed citations

11.

Mills, Jeffrey K. & David Needham. (2004). The Materials Engineering of Temperature-Sensitive Liposomes. Methods in enzymology on CD-ROM/Methods in enzymology. 387. 82–113. 48 indexed citations

12.

Brown, S F & David Needham. (2004). FACTORS INFLUENCING THE EARLY LIFE CHARACTERISTICS OF BITUMEN EMULSION MIXTURES. 1. 1 indexed citations

13.

Ravenzwaay, Bennard van, et al.. (2003). Comparative metabolism of 2,4-dichlorophenoxyacetic acid (2,4-D) in rat and dog. Xenobiotica. 33(8). 805–821. 35 indexed citations

14.

Zhelev, Doncho V., Natalia G. Stoicheva, Peter Scherrer, & David Needham. (2001). Interaction of Synthetic HA2 Influenza Fusion Peptide Analog with Model Membranes. Biophysical Journal. 81(1). 285–304. 38 indexed citations

15.

Kiser, Patrick F., et al.. (2000). オリゴ乳酸エステル及びオリゴグリコール酸エステルから成る対称生分解性架橋剤を含むポリ(HPMA)ヒドロゲルの設計と性能. Polymer preprints. 41(1). 712–713. 1 indexed citations

16.

Brown, S F & David Needham. (2000). A STUDY OF CEMENT MODIFIED BITUMEN EMULSION MIXTURES. Association of Asphalt Paving Technologists Proc. 69. 120 indexed citations

17.

Rawicz, W., Kevin C. Olbrich, Thomas J. McIntosh, David Needham, & EA Evans. (2000). Effect of Chain Length and Unsaturation on Elasticity of Lipid Bilayers. Biophysical Journal. 79(1). 328–339. 1533 indexed citations breakdown →

18.

McIntosh, Thomas J., Sidney A. Simon, David Needham, & C.H. Huang. (1992). Interbilayer interactions between sphingomyelin and sphingomyelin/cholesterol bilayers. Biochemistry. 31(7). 2020–2024. 77 indexed citations

19.

Needham, David, et al.. (1986). Points : Heart failure and breast enlargement suggesting cancer. BMJ. 292(6525). 961.1–961. 1 indexed citations

20.

Eley, D. D. & David Needham. (1984). Hydridization and catalysis by lanthanide films. Proceedings of the Royal Society of London A Mathematical and Physical Sciences. 393(1805). 257–276. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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