Xiaoguang Lei

11.6k total citations · 3 hit papers
208 papers, 7.5k citations indexed

About

Xiaoguang Lei is a scholar working on Molecular Biology, Organic Chemistry and Pharmacology. According to data from OpenAlex, Xiaoguang Lei has authored 208 papers receiving a total of 7.5k indexed citations (citations by other indexed papers that have themselves been cited), including 113 papers in Molecular Biology, 84 papers in Organic Chemistry and 53 papers in Pharmacology. Recurrent topics in Xiaoguang Lei's work include Microbial Natural Products and Biosynthesis (37 papers), Click Chemistry and Applications (22 papers) and Synthetic Organic Chemistry Methods (21 papers). Xiaoguang Lei is often cited by papers focused on Microbial Natural Products and Biosynthesis (37 papers), Click Chemistry and Applications (22 papers) and Synthetic Organic Chemistry Methods (21 papers). Xiaoguang Lei collaborates with scholars based in China, United States and Thailand. Xiaoguang Lei's co-authors include Xiaodong Wang, She Chen, Sudan He, Daohong Liao, Weilong Liu, Liming Sun, Lai Wang, Huayi Wang, Jiacong Yan and Zhigao Wang and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Xiaoguang Lei

200 papers receiving 7.4k citations

Hit Papers

Mixed Lineage Kinase Domain-like Protein Mediates Necrosi... 2012 2026 2016 2021 2012 2020 2025 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
    2012 2.1k citations Daohong Liao, Xiaoguang Lei et al. profile →
  2. Late-Stage Diversification of Natural Products
    2020 266 citations Benke Hong, Xiaoguang Lei et al. profile →
  3. A widespread plant defense compound disarms bacterial type III injectisome assembly
    2025 18 citations Xiaoguang Lei et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Xiaoguang Lei China 42 4.5k 2.1k 1.0k 947 726 208 7.5k
Meiyu Geng China 48 5.3k 1.2× 1.6k 0.7× 745 0.7× 852 0.9× 1.1k 1.6× 295 8.7k
Faustino Mollinedo Spain 55 5.8k 1.3× 979 0.5× 1.6k 1.6× 512 0.5× 1.1k 1.5× 207 9.6k
Ram A. Vishwakarma India 51 4.4k 1.0× 4.2k 1.9× 352 0.3× 1.3k 1.4× 331 0.5× 364 10.5k
Zhiyu Li China 43 3.1k 0.7× 755 0.4× 559 0.5× 825 0.9× 790 1.1× 291 6.0k
Jonathan B. Baell Australia 39 5.1k 1.1× 2.5k 1.1× 482 0.5× 929 1.0× 219 0.3× 177 9.2k
Ho Jeong Kwon South Korea 44 5.0k 1.1× 591 0.3× 562 0.5× 773 0.8× 1.2k 1.6× 204 7.3k
Dongmei Zhang China 43 3.5k 0.8× 628 0.3× 463 0.4× 664 0.7× 892 1.2× 202 6.3k
Wolfgang Sippl Germany 57 6.4k 1.4× 1.6k 0.8× 578 0.6× 830 0.9× 358 0.5× 303 10.3k
Dennis C. Liotta United States 57 5.7k 1.3× 3.8k 1.8× 693 0.7× 565 0.6× 312 0.4× 306 12.0k
Maurizio Pellecchia United States 56 7.7k 1.7× 1.1k 0.5× 1.5k 1.4× 407 0.4× 870 1.2× 205 11.1k

Countries citing papers authored by Xiaoguang Lei

Since Specialization
Citations

This map shows the geographic impact of Xiaoguang Lei's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xiaoguang Lei with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xiaoguang Lei more than expected).

Fields of papers citing papers by Xiaoguang Lei

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xiaoguang Lei. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xiaoguang Lei. The network helps show where Xiaoguang Lei may publish in the future.

Co-authorship network of co-authors of Xiaoguang Lei

This figure shows the co-authorship network connecting the top 25 collaborators of Xiaoguang Lei. A scholar is included among the top collaborators of Xiaoguang Lei based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Xiaoguang Lei. Xiaoguang Lei is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Fan, Junping, et al.. (2025). Structural Basis for Inhibition of Urate Reabsorption in URAT1. JACS Au. 5(3). 1308–1319. 1 indexed citations
2.
Wang, Xianwei, Haichuan Zhu, Zhou Gong, et al.. (2025). Small-Molecule Inhibitors of Transcription Factor PU.1 for the Treatment of Acute T Cell Lymphoblastic Leukemia and Organ Fibrosis. CCS Chemistry. 8(1). 319–340.
3.
Yang, Ying, Junping Fan, Jun Wu, et al.. (2025). Unveiling FERONIA receptor kinase–mediated cellular mechanisms with a small-molecule inhibitor. Proceedings of the National Academy of Sciences. 122(45). e2515322122–e2515322122.
4.
Guo, Fusheng, et al.. (2025). Photosensitized Gold-Catalyzed Cross-Couplings of Aryl Bromides. Journal of the American Chemical Society. 147(7). 5839–5850. 13 indexed citations
5.
Zhao, Wei, et al.. (2025). Quantitative Reactivity Profiling of Functional Arginine Residues in Human Cancer Cell Line Proteomes. Angewandte Chemie International Edition. 64(50). e202515603–e202515603.
6.
Fan, Junping, Daohong Liao, Jing Lei, et al.. (2024). Structural Pharmacology of TRPV4 Antagonists. Advanced Science. 11(25). e2401583–e2401583. 7 indexed citations
7.
Hong, Benke, et al.. (2024). Chemoenzymatic total synthesis of alchivemycin A. Nature Synthesis. 3(9). 1124–1133. 7 indexed citations
8.
Guo, Hui, Jing Zhang, Caixia Chen, et al.. (2024). Chrysomycins, Anti-Tuberculosis C-Glycoside Polyketides from Streptomyces sp. MS751. Marine Drugs. 22(6). 259–259. 3 indexed citations
9.
Liang, Kai, Yuebin Zhang, Qian Meng, et al.. (2024). Enzymatic Degradation of Deoxynivalenol with the Engineered Detoxification Enzyme Fhb7. SHILAP Revista de lepidopterología. 4(2). 619–634. 14 indexed citations
10.
Zhang, Jing, Fei Sun, Jing Ma, et al.. (2024). Discovery and Total Synthesis of Anhydrotuberosin as a STING Antagonist for Treating Autoimmune Diseases. Angewandte Chemie International Edition. 64(1). e202407641–e202407641. 3 indexed citations
11.
Gao, Lei, et al.. (2022). Enzymatic intermolecular Diels-Alder reactions in synthesis: From nature to design. SHILAP Revista de lepidopterología. 2. 100013–100013. 14 indexed citations
12.
Wei, Tiantian, Jue Wang, Wendong Chen, et al.. (2022). Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. eLife. 11. 14 indexed citations
13.
Tang, Yuliang, Zhou Gong, Rohit Jain, et al.. (2022). Characterization of protein unfolding by fast cross-linking mass spectrometry using di-ortho-phthalaldehyde cross-linkers. Nature Communications. 13(1). 39 indexed citations
14.
Gong, Zhou, Dong Xu, Shu-Qun Liu, et al.. (2022). Fast cross-linking by DOPA2 promotes the capturing of a stereospecific protein complex over nonspecific encounter complexes. Biophysics Reports. 8(5-6). 239–252. 5 indexed citations
15.
Cao, Yong, Yuliang Tang, Jianhua Wang, et al.. (2019). Improving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers. Nature Communications. 10(1). 3911–3911. 54 indexed citations
16.
Liu, Simin, Qinxue Wu, Omar Johnson, et al.. (2019). MRGPRX4 is a bile acid receptor for human cholestatic itch. eLife. 8. 103 indexed citations
17.
Wang, Xin, et al.. (2018). Research Progress of Covalent Inhibitors. Chinese Journal of Organic Chemistry. 38(9). 2296–2296. 4 indexed citations
18.
Lei, Xiaoguang, et al.. (2015). Expressions and clinical significance of autophagy-related markers Beclin1, LC3, and EGFR in human cervical squamous cell carcinoma. SHILAP Revista de lepidopterología. 2 indexed citations
19.
Lei, Xiaoguang, Richard P. Johnson, & John A. Porco. (2003). Total Synthesis of the Ubiquitin‐Activating Enzyme Inhibitor (+)‐Panepophenanthrin. Angewandte Chemie International Edition. 42(33). 3913–3917. 62 indexed citations
20.
Lei, Xiaoguang & Chad H. Stahl. (2001). Biotechnological development of effective phytases for mineral nutrition and environmental protection. Applied Microbiology and Biotechnology. 57(4). 474–481. 141 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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