Wei Shen Aik

1.8k total citations
22 papers, 1.2k citations indexed

About

Wei Shen Aik is a scholar working on Molecular Biology, Cancer Research and Materials Chemistry. According to data from OpenAlex, Wei Shen Aik has authored 22 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 4 papers in Cancer Research and 4 papers in Materials Chemistry. Recurrent topics in Wei Shen Aik's work include RNA modifications and cancer (16 papers), Epigenetics and DNA Methylation (7 papers) and Cancer-related gene regulation (7 papers). Wei Shen Aik is often cited by papers focused on RNA modifications and cancer (16 papers), Epigenetics and DNA Methylation (7 papers) and Cancer-related gene regulation (7 papers). Wei Shen Aik collaborates with scholars based in United Kingdom, United States and Hong Kong. Wei Shen Aik's co-authors include Christopher J. Schofield, M.A. McDonough, Marina Demetriades, Armin Thalhammer, John S. Scotti, Rasheduzzaman Chowdhury, Hwanho Choi, Lingzhi Gong, Jinrong Min and W. Tempel and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Wei Shen Aik

21 papers receiving 1.2k citations

Peers

Countries citing papers authored by Wei Shen Aik

Since Specialization

Citations

This map shows the geographic impact of Wei Shen Aik's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wei Shen Aik with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wei Shen Aik more than expected).

Fields of papers citing papers by Wei Shen Aik

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wei Shen Aik. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wei Shen Aik. The network helps show where Wei Shen Aik may publish in the future.

Co-authorship network of co-authors of Wei Shen Aik

This figure shows the co-authorship network connecting the top 25 collaborators of Wei Shen Aik. A scholar is included among the top collaborators of Wei Shen Aik based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Wei Shen Aik. Wei Shen Aik is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Evidence human FTO catalyses hydroxylation of N6-methyladenosine without direct formation of a demethylated product contrasting with ALKBH5/2/3 and bacterial AlkB 2025 ·Nucleic Acids Research ·(unknown), (unknown), (unknown), (unknown), E. Salah, (unknown), (unknown), Christopher J. Schofield, Wei Shen Aik	0
2	Modulator engineering of bifunctional metal-organic framework for synergistic catalysis 2024 ·Chem Catalysis ·(unknown), (unknown), Zhiyi Yang, Yoko Wong, Wei Shen Aik, Herman H. Y. Sung, Ian D. Williams, Yangjian Quan	1
3	Structural basis for Rab23 activation and a loss-of-function mutation in Carpenter syndrome 2024 ·Journal of Biological Chemistry ·(unknown), (unknown), (unknown), (unknown), Wei Shen Aik	1
4	In vitro methylation of the U7 snRNP subunits Lsm11 and SmE by the PRMT5/MEP50/pICln methylosome 2023 ·RNA ·Xiaocui Yang, (unknown), Min-Han Lin, (unknown), Agata Malinowska, Yadong Sun, Wei Shen Aik, Michał Dadlez, Liang Tong, Zbigniew Domiński	2
5	Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5–RNA complexes 2022 ·Nucleic Acids Research ·(unknown), (unknown), M.A. McDonough, Christopher J. Schofield, Wei Shen Aik	54
6	Reconstitution and biochemical assays of an active human histone pre-mRNA 3′-end processing machinery 2021 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Yadong Sun, Wei Shen Aik, Cheng Yang, William F. Marzluff, Zbigniew Domiński, Liang Tong	4
7	Structure of an active human histone pre-mRNA 3′-end processing machinery 2020 ·Science ·Yadong Sun, Yixiao Zhang, Wei Shen Aik, Cheng Yang, William F. Marzluff, Thomas Walz, Zbigniew Domiński, Liang Tong	77
8	Studies with recombinant U7 snRNP demonstrate that CPSF73 is both an endonuclease and a 5′–3′ exonuclease 2020 ·RNA ·Xiaocui Yang, Yadong Sun, Wei Shen Aik, William F. Marzluff, Liang Tong, Zbigniew Domiński	18
9	Composition and processing activity of a semi-recombinant holo U7 snRNP 2019 ·Nucleic Acids Research ·(unknown), Wei Shen Aik, Cheng Yang, Kaituo Wang, Z. Hong Zhou, Michał Dadlez, William F. Marzluff, Liang Tong, Zbigniew Domiński	12
10	The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3’-end processing 2017 ·PLoS ONE ·Wei Shen Aik, Min-Han Lin, Dazhi Tan, Ashutosh Tripathy, William F. Marzluff, Zbigniew Domiński, Chi‐Yuan Chou, Liang Tong	30
11	Pharmacological Inhibition of FTO 2015 ·PLoS ONE ·Fiona McMurray, Marina Demetriades, Wei Shen Aik, Myrte Merkestein, Holger Kramer, (unknown), Cheryl L. Scudamore, Tertius Hough, Sara Wells, Frances M. Ashcroft, M.A. McDonough, Christopher J. Schofield, Roger Cox	31
12	Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases 2015 ·Structure ·Shoichiro Horita, John S. Scotti, Cyrille C. Thinnes, (unknown), Armin Thalhammer, Wei Ge, Wei Shen Aik, Christoph Loenarz, Christopher J. Schofield, M.A. McDonough	32
13	Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-stranded N6-Methyladenosine RNA Demethylation 2014 ·Journal of Biological Chemistry ·Chao Xu, Ke Liu, W. Tempel, Marina Demetriades, Wei Shen Aik, Christopher J. Schofield, Jinrong Min	151
14	Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation 2014 ·Proceedings of the National Academy of Sciences ·John S. Scotti, Ivanhoe K. H. Leung, Wei Ge, Michael A. Bentley, Jordi Paps, Holger Kramer, Joongoo Lee, Wei Shen Aik, Hwanho Choi, Steinar M. Paulsen, Lesley A. H. Bowman, Nikita D. Loik, Shoichiro Horita, Chia-Hua Ho, Nadia J. Kershaw, Christoph M. Tang, Timothy D. W. Claridge, Gail M. Preston, M.A. McDonough, Christopher J. Schofield	57
15	Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition 2014 ·Nature Chemistry ·Jürgen Brem, Sander S. van Berkel, Wei Shen Aik, Anna M. Rydzik, Matthew B. Avison, I. Pettinati, (unknown), Akane Kawamura, James Spencer, Timothy D. W. Claridge, M.A. McDonough, Christopher J. Schofield	101
16	Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation 2014 ·Nucleic Acids Research ·Wei Shen Aik, John S. Scotti, Hwanho Choi, Lingzhi Gong, Marina Demetriades, Christopher J. Schofield, M.A. McDonough	200
17	Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO) 2013 ·Journal of Medicinal Chemistry ·Wei Shen Aik, Marina Demetriades, (unknown), Eleanor A. L. Bagg, Kar Kheng Yeoh, Clarisse Lejeune, Zhihong Zhang, M.A. McDonough, Christopher J. Schofield	134
18	Role of the jelly-roll fold in substrate binding by 2-oxoglutarate oxygenases 2012 ·Current Opinion in Structural Biology ·Wei Shen Aik, M.A. McDonough, Armin Thalhammer, Rasheduzzaman Chowdhury, Christopher J. Schofield	168
19	Dynamic Combinatorial Mass Spectrometry Leads to Inhibitors of a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase 2012 ·Journal of Medicinal Chemistry ·Esther C. Y. Woon, Marina Demetriades, Eleanor A. L. Bagg, Wei Shen Aik, Svetlana M. Krylova, (unknown), Mun Chiang Chan, Louise J. Walport, (unknown), Kevin N. Dack, M.A. McDonough, Sergey N. Krylov, Christopher J. Schofield	44
20	The potential of 2-oxoglutarate oxygenases acting on nucleic acids as therapeutic targets 2012 ·Drug Discovery Today Therapeutic Strategies ·Armin Thalhammer, Wei Shen Aik, Eleanor A. L. Bagg, Christopher J. Schofield	11

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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