Luke A. McNeill

9.6k total citations · 2 hit papers
29 papers, 5.7k citations indexed

About

Luke A. McNeill is a scholar working on Cancer Research, Molecular Biology and Genetics. According to data from OpenAlex, Luke A. McNeill has authored 29 papers receiving a total of 5.7k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Cancer Research, 19 papers in Molecular Biology and 7 papers in Genetics. Recurrent topics in Luke A. McNeill's work include Cancer, Hypoxia, and Metabolism (20 papers), Mitochondrial Function and Pathology (9 papers) and High Altitude and Hypoxia (6 papers). Luke A. McNeill is often cited by papers focused on Cancer, Hypoxia, and Metabolism (20 papers), Mitochondrial Function and Pathology (9 papers) and High Altitude and Hypoxia (6 papers). Luke A. McNeill collaborates with scholars based in United Kingdom, United States and Germany. Luke A. McNeill's co-authors include Christopher J. Schofield, Kirsty S. Hewitson, Peter J. Ratcliffe, Christopher W. Pugh, Jonathan Gleadle, Ya‐Min Tian, David R. Mole, Patrick H. Maxwell, Panu Jaakkola and Norma Masson and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Luke A. McNeill

29 papers receiving 5.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

2001 2.7k citations Andrew Epstein, Jonathan Gleadle et al. Cell profile →
Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family

2002 602 citations Kirsty S. Hewitson, Luke A. McNeill et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Luke A. McNeill United Kingdom	24	4.0k	3.6k	1.1k	751	480	29	5.7k
Kirsty S. Hewitson United Kingdom	34	4.8k 1.2×	4.5k 1.3×	1.3k 1.2×	879 1.2×	669 1.4×	48	7.0k
Mridul Mukherji United States	21	5.5k 1.4×	6.2k 1.7×	1.5k 1.4×	1.1k 1.4×	554 1.2×	40	9.3k
Holger Hebestreit United Kingdom	14	3.4k 0.9×	3.4k 1.0×	850 0.8×	819 1.1×	311 0.6×	17	5.7k
Ya‐Min Tian United Kingdom	25	8.1k 2.1×	7.1k 2.0×	2.0k 1.9×	1.5k 1.9×	811 1.7×	32	11.2k
Peppi Koivunen Finland	37	3.4k 0.9×	3.8k 1.1×	849 0.8×	776 1.0×	397 0.8×	101	6.3k
Nathalie M. Mazure France	39	4.1k 1.0×	5.5k 1.5×	600 0.6×	659 0.9×	263 0.5×	87	8.4k
Matthew E. Cockman United Kingdom	24	4.8k 1.2×	4.8k 1.3×	987 0.9×	863 1.1×	369 0.8×	35	7.1k
Rob A. Cairns Canada	24	5.4k 1.4×	6.1k 1.7×	449 0.4×	685 0.9×	431 0.9×	34	9.9k
Mircea Ivan United States	37	8.3k 2.1×	8.3k 2.3×	1.4k 1.3×	1.2k 1.6×	441 0.9×	80	11.9k
Haifeng Yang United States	18	4.4k 1.1×	4.1k 1.1×	1.0k 1.0×	714 1.0×	352 0.7×	38	6.2k

Countries citing papers authored by Luke A. McNeill

Since Specialization

Citations

This map shows the geographic impact of Luke A. McNeill's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Luke A. McNeill with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Luke A. McNeill more than expected).

Fields of papers citing papers by Luke A. McNeill

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Luke A. McNeill. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Luke A. McNeill. The network helps show where Luke A. McNeill may publish in the future.

Co-authorship network of co-authors of Luke A. McNeill

This figure shows the co-authorship network connecting the top 25 collaborators of Luke A. McNeill. A scholar is included among the top collaborators of Luke A. McNeill based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Luke A. McNeill. Luke A. McNeill is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Pfeffer, Inga, Lennart Brewitz, T. Krojer, et al.. (2019). Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern. Nature Communications. 10(1). 4910–4910. 42 indexed citations

Podobnik, Marjetka, Peter Savory, Nejc Rojko, et al.. (2016). Crystal structure of an invertebrate cytolysin pore reveals unique properties and mechanism of assembly. Nature Communications. 7(1). 11598–11598. 72 indexed citations

Conejo‐García, Ana, M.A. McDonough, Christoph Loenarz, et al.. (2010). Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor. Bioorganic & Medicinal Chemistry Letters. 20(20). 6125–6128. 20 indexed citations

Loenarz, Christoph, Jasmin Mecinović, Rasheduzzaman Chowdhury, et al.. (2009). Evidence for a Stereoelectronic Effect in Human Oxygen Sensing. Angewandte Chemie International Edition. 48(10). 1784–1787. 54 indexed citations

McDonough, M.A., Vivian Li, Emily Flashman, et al.. (2006). Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2). Proceedings of the National Academy of Sciences. 103(26). 9814–9819. 295 indexed citations

Hewitson, Kirsty S., Benoît M. R. Liénard, M.A. McDonough, et al.. (2006). Structural and Mechanistic Studies on the Inhibition of the Hypoxia-inducible Transcription Factor Hydroxylases by Tricarboxylic Acid Cycle Intermediates. Journal of Biological Chemistry. 282(5). 3293–3301. 190 indexed citations

McNeill, Luke A., Emily Flashman, Matthew R. Buck, et al.. (2005). Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate. Molecular BioSystems. 1(4). 321–324. 100 indexed citations

Banerji, Biswadip, Ana Conejo‐García, Luke A. McNeill, et al.. (2005). The inhibition of factor inhibiting hypoxia-inducible factor (FIH) by β-oxocarboxylic acids. Chemical Communications. 5438–5438. 27 indexed citations

Hewitson, Kirsty S., Luke A. McNeill, & Christopher J. Schofield. (2004). Modulating the Hypoxia-Inducible Factor Signaling Pathway: Applications From Cardiovascular Disease to Cancer. Current Pharmaceutical Design. 10(8). 821–833. 57 indexed citations

10.

Chapman, Timothy M., Baohua Gu, Timothy M. Block, et al.. (2004). Glyco- and Peptidomimetics from Three-Component Joullié−Ugi Coupling Show Selective Antiviral Activity. Journal of the American Chemical Society. 127(2). 506–507. 71 indexed citations

11.

McNeill, Luke A., Lucas Bethge, Kirsty S. Hewitson, & Christopher J. Schofield. (2004). A fluorescence-based assay for 2-oxoglutarate-dependent oxygenases. Analytical Biochemistry. 336(1). 125–131. 55 indexed citations

12.

Elkins, Jonathan M., Kirsty S. Hewitson, Luke A. McNeill, et al.. (2003). Structure of Factor-inhibiting Hypoxia-inducible Factor (HIF) Reveals Mechanism of Oxidative Modification of HIF-1α. Journal of Biological Chemistry. 278(3). 1802–1806. 326 indexed citations

13.

Schlemminger, Imre, David R. Mole, Luke A. McNeill, et al.. (2003). Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases. Bioorganic & Medicinal Chemistry Letters. 13(8). 1451–1454. 53 indexed citations

14.

Hewitson, Kirsty S., Luke A. McNeill, Jonathan M. Elkins, & Christopher J. Schofield. (2003). The role of iron and 2-oxoglutarate oxygenases in signalling. Biochemical Society Transactions. 31(3). 510–515. 42 indexed citations

15.

Mole, David R., Imre Schlemminger, Luke A. McNeill, et al.. (2003). 2-Oxoglutarate analogue inhibitors of hif prolyl hydroxylase. Bioorganic & Medicinal Chemistry Letters. 13(16). 2677–2680. 126 indexed citations

16.

Hewitson, Kirsty S., Luke A. McNeill, Ya‐Min Tian, et al.. (2002). Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family. Journal of Biological Chemistry. 277(29). 26351–26355. 602 indexed citations breakdown →

17.

McNeill, Luke A., Kirsty S. Hewitson, Timothy D. W. Claridge, et al.. (2002). Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the β-carbon of asparagine-803. Biochemical Journal. 367(3). 571–575. 181 indexed citations

18.

McNeill, Luke A., Kirsty S. Hewitson, Jonathan Gleadle, et al.. (2002). The use of dioxygen by HIF prolyl hydroxylase (PHD1). Bioorganic & Medicinal Chemistry Letters. 12(12). 1547–1550. 95 indexed citations

19.

Epstein, Andrew, Jonathan Gleadle, Luke A. McNeill, et al.. (2001). C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation. Cell. 107(1). 43–54. 2746 indexed citations breakdown →

20.

Taylor, Peter N., Michael J. O’Connell, Luke A. McNeill, et al.. (2000). Insulated Molecular Wires: Synthesis of Conjugated Polyrotaxanes by Suzuki Coupling in Water. Angewandte Chemie International Edition. 39(19). 3456–3460. 216 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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