Frederick J. Sheedy

11.5k total citations · 7 hit papers
36 papers, 8.9k citations indexed

About

Frederick J. Sheedy is a scholar working on Immunology, Cancer Research and Molecular Biology. According to data from OpenAlex, Frederick J. Sheedy has authored 36 papers receiving a total of 8.9k indexed citations (citations by other indexed papers that have themselves been cited), including 23 papers in Immunology, 14 papers in Cancer Research and 8 papers in Molecular Biology. Recurrent topics in Frederick J. Sheedy's work include MicroRNA in disease regulation (11 papers), Immune cells in cancer (10 papers) and Immune responses and vaccinations (8 papers). Frederick J. Sheedy is often cited by papers focused on MicroRNA in disease regulation (11 papers), Immune cells in cancer (10 papers) and Immune responses and vaccinations (8 papers). Frederick J. Sheedy collaborates with scholars based in Ireland, United States and Canada. Frederick J. Sheedy's co-authors include Kathryn J. Moore, Edward A. Fisher, Luke O'neill, Claire E. McCoy, Katey J. Rayner, Eva M. Pålsson‐McDermott, Laura E. Gleeson, Elizabeth J. Hennessy, Bhama Ramkhelawon and Joseph Keane and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Frederick J. Sheedy

35 papers receiving 8.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Macrophages in atherosclerosis: a dynamic balance

2013 2.0k citations Kathryn J. Moore, Frederick J. Sheedy et al. Nature reviews. Immunology profile →
Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

2015 1.0k citations Eva M. Pålsson‐McDermott, Annie M. Curtis et al. Cell Metabolism profile →
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

2009 806 citations Frederick J. Sheedy, Eva M. Pålsson‐McDermott et al. profile →
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

2013 731 citations Frederick J. Sheedy, Katey J. Rayner et al. profile →
MicroRNAs: the fine-tuners of Toll-like receptor signalling

2011 728 citations Luke O'neill, Frederick J. Sheedy et al. Nature reviews. Immunology profile →
Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

2011 566 citations Katey J. Rayner, Frederick J. Sheedy et al. Journal of Clinical Investigation profile →
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

2011 556 citations Katey J. Rayner, Christine Esau et al. profile →

Peers

Countries citing papers authored by Frederick J. Sheedy

Since Specialization

Citations

This map shows the geographic impact of Frederick J. Sheedy's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frederick J. Sheedy with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frederick J. Sheedy more than expected).

Fields of papers citing papers by Frederick J. Sheedy

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frederick J. Sheedy. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frederick J. Sheedy. The network helps show where Frederick J. Sheedy may publish in the future.

Co-authorship network of co-authors of Frederick J. Sheedy

This figure shows the co-authorship network connecting the top 25 collaborators of Frederick J. Sheedy. A scholar is included among the top collaborators of Frederick J. Sheedy based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frederick J. Sheedy. Frederick J. Sheedy is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Trained immunity causes myeloid cell hypercoagulability 2025 ·Science Advances ·Aisling M. Rehill, (unknown), (unknown), Tristram A. J. Ryan, (unknown), Gemma León, Hugo Charles‐Messance, Edmund Gilbert, (unknown), Emily A. Day, Judith A. Coppinger, Jamie M. O’Sullivan, Corrina McMahon, James S. O’Donnell, Annie M. Curtis, Luke O'neill, Frederick J. Sheedy, Roger J. S. Preston	3
2	Adiposity, immunity, and inflammation: interrelationships in health and disease: a report from 24th Annual Harvard Nutrition Obesity Symposium, June 2023 2024 ·American Journal of Clinical Nutrition ·M. Furkan Burak, Takara L. Stanley, Elizabeth A. Lawson, (unknown), Lydia Lynch, Alyssa H. Hasty, Ana I. Domingos, Vishwa Deep Dixit, Gökhan S. Hotamışlıgil, Frederick J. Sheedy, Anne E. Dixon, Tina E. Brinkley, Joseph A. Hill, Marc Y. Donath, Steven Grinspoon	5
3	β-glucans from Agaricus bisporus mushroom products drive Trained Immunity 2024 ·Frontiers in Nutrition ·(unknown), (unknown), (unknown), Shilong Chen, (unknown), (unknown), (unknown), Hugo Charles‐Messance, Elaine Dempsey, (unknown), Jude Wilson, Sinéad C. Corr, Shipra Nagar, Frederick J. Sheedy	12
4	Recognition of yeast β-glucan particles triggers immunometabolic signaling required for trained immunity 2024 ·iScience ·(unknown), (unknown), Mimmi L. E. Lundahl, Hugo Charles‐Messance, (unknown), (unknown), (unknown), Hannah Prendeville, (unknown), Aaron M. Walsh, (unknown), (unknown), (unknown), Elaine Dempsey, Sinéad C. Corr, Frederick J. Sheedy	12
5	Negative Regulation of Innate Immune Signaling by Components of the Button Mushroom Agaricus bisporus 2023 ·Molecular Nutrition & Food Research ·(unknown), Elaine Dempsey, (unknown), (unknown), (unknown), Hannah Prendeville, (unknown), (unknown), Dearbhla M Murphy, (unknown), Jude Wilson, Sinéad C. Corr, Frederick J. Sheedy	4
6	Respiratory Tract Infections in Diabetes – Lessons From Tuberculosis and Influenza to Guide Understanding of COVID-19 Severity 2022 ·Frontiers in Endocrinology ·(unknown), Katina D. Hulme, Ronan Thibaut, Jagadeesh Bayry, Frederick J. Sheedy, Kirsty R. Short, Fawaz Alzaïd	21
7	Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses 2022 ·eLife ·Mimmi L. E. Lundahl, (unknown), Dylan G. Ryan, (unknown), Niamh C. Williams, Ming Yang, (unknown), (unknown), Filipa Lebre, Aoife L. Gorman, (unknown), Adrian P. Bracken, Christian Frezza, Frederick J. Sheedy, Eoin M. Scanlan, Luke O'neill, Stephen V. Gordon, Ed C. Lavelle	58
8	Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21 2020 ·Cell Reports ·(unknown), Hugo Charles‐Messance, Seónadh M. O’Leary, Laura E. Gleeson, Natalia Muñoz‐Wolf, (unknown), (unknown), Daniel Johnston, Michelle A. Williams, Alicia Smyth, Mireille Ouimet, Kathryn J. Moore, Ed C. Lavelle, Sinéad C. Corr, Stephen V. Gordon, Joseph Keane, Frederick J. Sheedy	108
9	Obesity, COVID-19 and innate immunometabolism 2020 ·British Journal Of Nutrition ·Laura E. Gleeson, Helen M. Roche, Frederick J. Sheedy	22
10	An Army Marches on Its Stomach: Metabolic Intermediates as Antimicrobial Mediators in Mycobacterium tuberculosis Infection 2020 ·Frontiers in Cellular and Infection Microbiology ·(unknown), Frederick J. Sheedy	5
11	Train to Lose: Innate Immune Memory in Metaflammation 2020 ·Molecular Nutrition & Food Research ·Hugo Charles‐Messance, Frederick J. Sheedy	12
12	Cigarette Smoking Impairs the Bioenergetic Immune Response to Mycobacterium tuberculosis Infection 2018 ·American Journal of Respiratory Cell and Molecular Biology ·Laura E. Gleeson, Seónadh M. O’Leary, D Ryan, Anne Marie McLaughlin, Frederick J. Sheedy, Joseph Keane	42
13	Metabolic reprogramming & inflammation: Fuelling the host response to pathogens 2016 ·Seminars in Immunology ·Laura E. Gleeson, Frederick J. Sheedy	53
14	Turning 21: Induction of miR-21 as a Key Switch in the Inflammatory Response 2015 ·Frontiers in Immunology ·Frederick J. Sheedy	402
15	Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages breakdown → 2015 ·Cell Metabolism ·Eva M. Pålsson‐McDermott, Annie M. Curtis, Gautam Goel, Mario Lauterbach, Frederick J. Sheedy, Laura E. Gleeson, (unknown), Susan R. Quinn, Raquel Domingo-Fernandéz, Daniel Johnston, Jian‐kang Jiang, William J. Israelsen, Joseph Keane, Craig J. Thomas, Clary B. Clish, Matthew G. Vander Heiden, Ramnik J. Xavier, Luke O'neill	1029
16	Macrophages in atherosclerosis: a dynamic balance breakdown → 2013 ·Nature reviews. Immunology ·Kathryn J. Moore, Frederick J. Sheedy, Edward A. Fisher	1994
17	Antagonism of miR-33 in Mice Promotes Reverse Cholesterol Transport and Regression of Atherosclerosis 2011 ·Journal of Vascular Surgery ·Katey J. Rayner, Frederick J. Sheedy, Christine Esau	3
18	Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis breakdown → 2011 ·Journal of Clinical Investigation ·Katey J. Rayner, Frederick J. Sheedy, Christine Esau, Farah Hussain, Ryan E. Temel, Saj Parathath, Janine M. van Gils, (unknown), Aaron N. Chang, Yajaira Suárez, Carlos Fernández‐Hernando, Edward A. Fisher, Kathryn J. Moore	566
19	MicroRNAs: the fine-tuners of Toll-like receptor signalling breakdown → 2011 ·Nature reviews. Immunology ·Luke O'neill, Frederick J. Sheedy, Claire E. McCoy	728
20	The Mal/TIRAP S180L and TLR4 G299D polymorphisms are not associated with susceptibility to, or severity of, rheumatoid arthritis 2008 ·Annals of the Rheumatic Diseases ·Frederick J. Sheedy, Ιωάννα Μαρίνου, Luke O'neill, Anthony G. Wilson	34

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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