Eric Metzen

8.2k total citations · 1 hit paper
51 papers, 6.8k citations indexed

About

Eric Metzen is a scholar working on Molecular Biology, Cancer Research and Genetics. According to data from OpenAlex, Eric Metzen has authored 51 papers receiving a total of 6.8k indexed citations (citations by other indexed papers that have themselves been cited), including 34 papers in Molecular Biology, 34 papers in Cancer Research and 13 papers in Genetics. Recurrent topics in Eric Metzen's work include Cancer, Hypoxia, and Metabolism (31 papers), Mitochondrial Function and Pathology (14 papers) and High Altitude and Hypoxia (11 papers). Eric Metzen is often cited by papers focused on Cancer, Hypoxia, and Metabolism (31 papers), Mitochondrial Function and Pathology (14 papers) and High Altitude and Hypoxia (11 papers). Eric Metzen collaborates with scholars based in Germany, Finland and China. Eric Metzen's co-authors include Wolfgang Jelkmann, Joachim Fandrey, Thomas Hellwig‐Bürgel, Peter J. Ratcliffe, Panu Jaakkola, Norma Masson, Luke A. McNeill, Andrew Epstein, Christopher W. Pugh and Patrick H. Maxwell and has published in prestigious journals such as Cell, Journal of Biological Chemistry and Blood.

In The Last Decade

Eric Metzen

51 papers receiving 6.7k citations

Hit Papers

C. elegans EGL-9 and Mammalian Homologs Define a Family o... 2001 2026 2009 2017 2001 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
    2001 2.7k citations Andrew Epstein, Jonathan Gleadle et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Eric Metzen Germany 30 4.5k 3.8k 1.3k 1.1k 590 51 6.8k
Norma Masson United Kingdom 23 4.5k 1.0× 4.2k 1.1× 1.2k 1.0× 818 0.7× 516 0.9× 34 6.5k
Matthew E. Cockman United Kingdom 24 4.8k 1.1× 4.8k 1.3× 987 0.8× 863 0.8× 785 1.3× 35 7.1k
Peppi Koivunen Finland 37 3.4k 0.8× 3.8k 1.0× 849 0.7× 776 0.7× 458 0.8× 101 6.3k
Sandra W. Leung United States 7 4.9k 1.1× 4.4k 1.2× 1.2k 0.9× 1.1k 1.0× 806 1.4× 7 7.5k
Haifeng Yang United States 18 4.4k 1.0× 4.1k 1.1× 1.0k 0.8× 714 0.6× 650 1.1× 38 6.2k
Richard K. Bruick United States 36 5.0k 1.1× 5.9k 1.6× 1.2k 1.0× 1.2k 1.1× 704 1.2× 47 9.7k
Holger Hebestreit United Kingdom 14 3.4k 0.8× 3.4k 0.9× 850 0.7× 819 0.7× 488 0.8× 17 5.7k
Edurne Berra France 43 4.7k 1.0× 6.0k 1.6× 1.1k 0.8× 1.1k 1.0× 1.1k 1.8× 69 9.4k
Erik Laughner United States 14 5.7k 1.3× 5.0k 1.3× 1.1k 0.9× 927 0.8× 1.2k 2.1× 14 8.1k
Gin-Wen Chang United Kingdom 13 3.8k 0.8× 3.8k 1.0× 744 0.6× 584 0.5× 692 1.2× 18 5.7k

Countries citing papers authored by Eric Metzen

Since Specialization
Citations

This map shows the geographic impact of Eric Metzen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eric Metzen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eric Metzen more than expected).

Fields of papers citing papers by Eric Metzen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eric Metzen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eric Metzen. The network helps show where Eric Metzen may publish in the future.

Co-authorship network of co-authors of Eric Metzen

This figure shows the co-authorship network connecting the top 25 collaborators of Eric Metzen. A scholar is included among the top collaborators of Eric Metzen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Eric Metzen. Eric Metzen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Schreiber, Timm, et al.. (2024). Reduced vacuolar ATPase protects mice from Friend virus infection – an unintended but instructive effect in Hif-2afl mice. Journal of Cell Science. 137(12). 1 indexed citations
2.
3.
Baumann, J, et al.. (2021). Overcoming hypoxia-induced resistance of pancreatic and lung tumor cells by disrupting the PERK-NRF2-HIF-axis. Cell Death and Disease. 12(1). 82–82. 36 indexed citations
4.
Pompsch, Mosche, et al.. (2018). Autophagy induced by ionizing radiation promotes cell death over survival in human colorectal cancer cells. Experimental Cell Research. 374(1). 29–37. 31 indexed citations
5.
Neumann, Fabian, Alexandra Wolf, Mosche Pompsch, et al.. (2017). PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR). Cell Death and Disease. 8(8). e2986–e2986. 83 indexed citations
6.
Matschke, Johann, Diana Klein, René Handrick, et al.. (2016). Targeted Inhibition of Glutamine-Dependent Glutathione Metabolism Overcomes Death Resistance Induced by Chronic Cycling Hypoxia. Antioxidants and Redox Signaling. 25(2). 89–107. 49 indexed citations
7.
Jin, Fengyan, Ulf Brockmeier, Friedrich Otterbach, & Eric Metzen. (2012). New Insight into the SDF-1/CXCR4 Axis in a Breast Carcinoma Model: Hypoxia-Induced Endothelial SDF-1 and Tumor Cell CXCR4 Are Required for Tumor Cell Intravasation. Molecular Cancer Research. 10(8). 1021–1031. 107 indexed citations
8.
Jin, Fengyan, Huifan Ji, Chunshu Jia, et al.. (2012). Synergistic Antitumor Effects of Endostar in Combination with Oxaliplatin via Inhibition of HIF and CXCR4 in the Colorectal Cell Line SW1116. PLoS ONE. 7(10). e47161–e47161. 17 indexed citations
9.
10.
Su, Yun, Martin Loos, Nathalia A. Giese, et al.. (2010). PHD3 regulates differentiation, tumour growth and angiogenesis in pancreatic cancer. British Journal of Cancer. 103(10). 1571–1579. 61 indexed citations
11.
Rantanen, Krista, et al.. (2008). Prolyl Hydroxylase PHD3 Activates Oxygen-dependent Protein Aggregation. Molecular Biology of the Cell. 19(5). 2231–2240. 52 indexed citations
12.
Depping, Reinhard, Susann Schindler, Beate Friedrich, et al.. (2007). Nuclear translocation of hypoxia-inducible factors (HIFs): Involvement of the classical importin α/β pathway. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1783(3). 394–404. 115 indexed citations
13.
Jelkmann, Wolfgang, et al.. (2007). Hydroxylation of Hypoxia-Inducible Transcription Factors and Chemical Compounds Targeting the HIF-α Hydroxylases. Current Medicinal Chemistry. 14(17). 1853–1862. 78 indexed citations
14.
15.
Hellwig‐Bürgel, Thomas, Daniel P. Stiehl, Anika E. Wagner, Eric Metzen, & Wolfgang Jelkmann. (2005). Review: Hypoxia-Inducible Factor-1 (HIF-1): A Novel Transcription Factor in Immune Reactions. Journal of Interferon & Cytokine Research. 25(6). 297–310. 217 indexed citations
16.
Berchner‐Pfannschmidt, Utta, Frank Petrat, Patrícia Freitag, et al.. (2004). Chelation of Cellular Calcium Modulates Hypoxia-inducible Gene Expression through Activation of Hypoxia-inducible Factor-1α. Journal of Biological Chemistry. 279(43). 44976–44986. 58 indexed citations
17.
Metzen, Eric, Jie Zhou, Wolfgang Jelkmann, Joachim Fandrey, & Bernhard Brüne. (2003). Nitric Oxide Impairs Normoxic Degradation of HIF-1α by Inhibition of Prolyl Hydroxylases. Molecular Biology of the Cell. 14(8). 3470–3481. 351 indexed citations
18.
Metzen, Eric, et al.. (2001). Cytosolic Ca<sup>2+</sup> Levels and DNA Synthesis of Human Umbilical Vein Endothelial Cell Cultures are Unresponsive to Thrombopoietin Treatment. Cellular Physiology and Biochemistry. 11(4). 197–202. 2 indexed citations
19.
Epstein, Andrew, Jonathan Gleadle, Luke A. McNeill, et al.. (2001). C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation. Cell. 107(1). 43–54. 2746 indexed citations breakdown →
20.
Kreft, Burkhard, et al.. (2000). Hypoxia and interleukin-1β stimulate vascular endothelial growth factor production in human proximal tubular cells. Kidney International. 58(1). 43–50. 104 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Norma Masson Breakdown of academic impact, for papers by Matthew E. Cockman Breakdown of academic impact, for papers by Peppi Koivunen Breakdown of academic impact, for papers by Sandra W. Leung Breakdown of academic impact, for papers by Haifeng Yang Breakdown of academic impact, for papers by Richard K. Bruick Breakdown of academic impact, for papers by Holger Hebestreit Breakdown of academic impact, for papers by Edurne Berra Breakdown of academic impact, for papers by Erik Laughner Breakdown of academic impact, for papers by Gin-Wen Chang
Rankless by CCL
2026