Lufen Chang

14.6k total citations · 5 hit papers
27 papers, 12.2k citations indexed

About

Lufen Chang is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Lufen Chang has authored 27 papers receiving a total of 12.2k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 15 papers in Cancer Research and 13 papers in Oncology. Recurrent topics in Lufen Chang's work include NF-κB Signaling Pathways (12 papers), Melanoma and MAPK Pathways (8 papers) and Cancer-related Molecular Pathways (8 papers). Lufen Chang is often cited by papers focused on NF-κB Signaling Pathways (12 papers), Melanoma and MAPK Pathways (8 papers) and Cancer-related Molecular Pathways (8 papers). Lufen Chang collaborates with scholars based in United States, Taiwan and Japan. Lufen Chang's co-authors include Michael Karin, Shin Maeda, Gürol Tuncman, Jiro Hirosumi, Gökhan S. Hotamışlıgil, Kazuhisa Maeda, Cem Z. Görgün, K. Teoman Uysal, Hideaki Kamata and Hajime Hirata and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Lufen Chang

27 papers receiving 12.0k citations

Hit Papers

Mammalian MAP kinase signalling cascades 2001 2026 2009 2017 2001 2002 2005 2001 2006 1000 2.0k 3.0k 4.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Mammalian MAP kinase signalling cascades
    2001 4.3k citations Lufen Chang, Michael Karin Nature profile →
  2. A central role for JNK in obesity and insulin resistance
    2002 2.6k citations Jiro Hirosumi, Gürol Tuncman et al. Nature profile →
  3. Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases
    2005 1.5k citations Hideaki Kamata, Shinichi Honda et al. Cell profile →
  4. c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis
    2001 691 citations Zuoning Han, David L. Boyle et al. Journal of Clinical Investigation profile →
  5. The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover
    2006 582 citations Lufen Chang, Hideaki Kamata et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Lufen Chang United States 21 7.2k 2.3k 2.1k 2.0k 1.8k 27 12.2k
Sebastian Wesselborg Germany 56 7.2k 1.0× 3.9k 1.7× 2.6k 1.2× 1.5k 0.8× 1.6k 0.9× 136 13.4k
Nika N. Danial United States 35 7.2k 1.0× 1.5k 0.7× 1.3k 0.6× 1.2k 0.6× 1.5k 0.8× 56 10.4k
Lisardo Boscá Spain 59 5.6k 0.8× 3.1k 1.3× 1.7k 0.8× 1.8k 0.9× 893 0.5× 284 12.8k
Spencer B. Gibson Canada 53 7.8k 1.1× 2.1k 0.9× 3.0k 1.4× 2.2k 1.1× 1.8k 1.0× 163 13.0k
Atsushi Matsuzawa Japan 51 7.0k 1.0× 2.5k 1.1× 1.4k 0.7× 1.6k 0.8× 914 0.5× 124 11.3k
Masashi Narita United Kingdom 45 8.9k 1.2× 1.7k 0.7× 1.8k 0.9× 1.6k 0.8× 1.8k 1.0× 104 13.1k
Mathieu Laplante Canada 36 8.9k 1.2× 1.6k 0.7× 3.3k 1.6× 1.6k 0.8× 1.1k 0.6× 78 15.1k
Wei‐Xing Zong United States 43 8.4k 1.2× 2.0k 0.9× 2.1k 1.0× 2.2k 1.1× 2.1k 1.1× 79 12.0k
María T. Díaz‐Meco United States 72 11.1k 1.5× 2.5k 1.1× 4.1k 1.9× 3.3k 1.7× 2.7k 1.5× 155 16.2k
David Gius United States 65 8.0k 1.1× 1.0k 0.4× 2.4k 1.1× 2.6k 1.3× 1.6k 0.9× 148 13.7k

Countries citing papers authored by Lufen Chang

Since Specialization
Citations

This map shows the geographic impact of Lufen Chang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lufen Chang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lufen Chang more than expected).

Fields of papers citing papers by Lufen Chang

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lufen Chang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lufen Chang. The network helps show where Lufen Chang may publish in the future.

Co-authorship network of co-authors of Lufen Chang

This figure shows the co-authorship network connecting the top 25 collaborators of Lufen Chang. A scholar is included among the top collaborators of Lufen Chang based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lufen Chang. Lufen Chang is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Chang, Lufen, Hu Zhou, Jing Gao, et al.. (2018). ITCH nuclear translocation and H1.2 polyubiquitination negatively regulate the DNA damage response. Nucleic Acids Research. 47(2). 824–842. 18 indexed citations
2.
Zheng, Li, Jia Jia, Huifang Dai, et al.. (2017). Triptolide-Assisted Phosphorylation of p53 Suppresses Inflammation-Induced NF-κB Survival Pathways in Cancer Cells. Molecular and Cellular Biology. 37(15). 32 indexed citations
3.
Chang, Lufen, Robin Guo, Qin Huang, & Yun Yen. (2013). Chromosomal Instability Triggered by Rrm2b Loss Leads to IL-6 Secretion and Plasmacytic Neoplasms. Cell Reports. 3(5). 1389–1397. 23 indexed citations
4.
Kuo, Mei-Ling, Lijun Xue, Terence T. Yen, et al.. (2012). RRM2B Suppresses Activation of the Oxidative Stress Pathway and is Up-regulated by P53 During Senescence. Scientific Reports. 2(1). 822–822. 32 indexed citations
5.
Zhang, Lisheng, Lixin Yang, Xiyong Liu, et al.. (2012). MicroRNA-657 promotes tumorigenesis in hepatocellular carcinoma by targeting transducin-like enhancer protein 1 through nuclear factor kappa B pathways. Hepatology. 57(5). 1919–1930. 55 indexed citations
6.
Zhang, Keqiang, Jun Wu, Xiwei Wu, et al.. (2011). p53R2 Inhibits the Proliferation of Human Cancer Cells in Association with Cell-Cycle Arrest. Molecular Cancer Therapeutics. 10(2). 269–278. 43 indexed citations
7.
Guo, Robin, Lufen Chang, Zheng Liu, et al.. (2011). Canonical Nuclear Factor κB Pathway Links Tumorigenesis of Synchronous Mantle-Cell Lymphoma, Clear-Cell Renal-Cell Carcinoma, and GI Stromal Tumor. Journal of Clinical Oncology. 29(10). e257–e261. 7 indexed citations
8.
Chang, Lufen, Hideaki Kamata, Giovanni Solinas, et al.. (2006). The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover. Cell. 124(3). 601–613. 582 indexed citations breakdown →
9.
Kamata, Hideaki, Shinichi Honda, Shin Maeda, et al.. (2005). Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases. Cell. 120(5). 649–661. 1526 indexed citations breakdown →
10.
Chang, Lufen, Ying Jones, Mark H. Ellisman, Lawrence S.B. Goldstein, & Michael Karin. (2003). JNK1 Is Required for Maintenance of Neuronal Microtubules and Controls Phosphorylation of Microtubule-Associated Proteins. Developmental Cell. 4(4). 521–533. 310 indexed citations
11.
Hirosumi, Jiro, Gürol Tuncman, Lufen Chang, et al.. (2002). A central role for JNK in obesity and insulin resistance. Nature. 420(6913). 333–336. 2627 indexed citations breakdown →
12.
Han, Zuoning, Lufen Chang, Yuji Yamanishi, Michael Karin, & Gary S. Firestein. (2002). Joint damage and inflammation in c‐Jun N‐terminal kinase 2 knockout mice with passive murine collagen‐induced arthritis. Arthritis & Rheumatism. 46(3). 818–823. 101 indexed citations
13.
Han, Zuoning, David L. Boyle, Lufen Chang, et al.. (2001). c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. Journal of Clinical Investigation. 108(1). 73–81. 49 indexed citations
14.
Han, Zuoning, David L. Boyle, Lufen Chang, et al.. (2001). c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. Journal of Clinical Investigation. 108(1). 73–81. 691 indexed citations breakdown →
15.
Chang, Lufen & Michael Karin. (2001). Mammalian MAP kinase signalling cascades. Nature. 410(6824). 37–40. 4344 indexed citations breakdown →
16.
Jiménez, Benilde, Olga V. Volpert, Frank Reiher, et al.. (2001). c-Jun N-terminal kinase activation is required for the inhibition of neovascularization by thrombospondin-1. Oncogene. 20(26). 3443–3448. 71 indexed citations
17.
Sabapathy, Kanaga, Wolfram Jochum, Konrad Hochedlinger, et al.. (1999). Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2. Mechanisms of Development. 89(1-2). 115–124. 294 indexed citations
18.
Chang, Lufen & Mary Ann Thompson. (1996). Activity of the Distal Positive Element of the Peripherin Gene Is Dependent on Proteins Binding to an Ets-like Recognition Site and a Novel Inverted Repeat Site. Journal of Biological Chemistry. 271(11). 6467–6475. 12 indexed citations
19.
Kondoh, Tatsuro, Hitoshi Kanno, Lufen Chang, & Akira Yoshida. (1991). Identification of common variant alleles of the human guanosine monophosphate reductase gene. Human Genetics. 88(2). 225–7. 4 indexed citations
20.
Kondoh, Tatsuro, Hitoshi Kanno, Lufen Chang, & A Yoshida. (1991). Genomic structure and expression of human guanosine monophosphate reductase. Human Genetics. 88(2). 219–24. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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