Shigeomi Shimizu

22.3k total citations · 10 hit papers
146 papers, 18.5k citations indexed

About

Shigeomi Shimizu is a scholar working on Molecular Biology, Epidemiology and Cell Biology. According to data from OpenAlex, Shigeomi Shimizu has authored 146 papers receiving a total of 18.5k indexed citations (citations by other indexed papers that have themselves been cited), including 92 papers in Molecular Biology, 56 papers in Epidemiology and 26 papers in Cell Biology. Recurrent topics in Shigeomi Shimizu's work include Autophagy in Disease and Therapy (49 papers), Cell death mechanisms and regulation (43 papers) and Mitochondrial Function and Pathology (31 papers). Shigeomi Shimizu is often cited by papers focused on Autophagy in Disease and Therapy (49 papers), Cell death mechanisms and regulation (43 papers) and Mitochondrial Function and Pathology (31 papers). Shigeomi Shimizu collaborates with scholars based in Japan, United States and United Kingdom. Shigeomi Shimizu's co-authors include Yoshihide Tsujimoto, Masashi Narita, Satoko Arakawa, Hikaru Matsuda, Wataru Kamiike, Toku Kanaseki, Kinya Otsu, Takashi Nakagawa, Hirofumi Yamaguchi and Toshinori Ito and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Shigeomi Shimizu

142 papers receiving 18.3k citations

Hit Papers

Bcl-2 family proteins regulate the release of apoptogenic... 1995 2026 2005 2015 1999 2005 2004 2009 2009 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
    1999 1.8k citations Shigeomi Shimizu, Masashi Narita et al. profile →
  2. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
    2005 1.3k citations Shigeomi Shimizu, Yoshihide Tsujimoto et al. profile →
  3. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
    2004 1.1k citations Shigeomi Shimizu, Toku Kanaseki et al. profile →
  4. Discovery of Atg5/Atg7-independent alternative macroautophagy
    2009 899 citations Satoko Arakawa, Hirofumi Yamaguchi et al. profile →
  5. Autophagy mediates the mitotic senescence transition
    2009 836 citations Andrew Young, Masako Narita et al. Genes & Development profile →
  6. Bax interacts with the permeability transition pore to induce permeability transition and cytochromecrelease in isolated mitochondria
    1998 827 citations Masashi Narita, Shigeomi Shimizu et al. Proceedings of the National Academy of Sciences profile →
  7. Bcl‐2 family: Life‐or‐death switch
    2000 591 citations Yoshihide Tsujimoto, Shigeomi Shimizu profile →
  8. Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL
    1995 538 citations Shigeomi Shimizu, Yoshihide Tsujimoto et al. profile →
  9. Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes
    2011 459 citations Masako Narita, Andrew Young et al. Science profile →
  10. Hypertrophy and Unconventional Cell Division of Hepatocytes Underlie Liver Regeneration
    2012 344 citations Satoko Arakawa, Shigeomi Shimizu et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Shigeomi Shimizu Japan 58 12.5k 4.9k 1.9k 1.9k 1.8k 146 18.5k
Xiao-Ming Yin United States 59 9.6k 0.8× 6.2k 1.3× 2.1k 1.1× 1.2k 0.6× 1.8k 1.0× 96 16.2k
Kinya Otsu Japan 57 10.8k 0.9× 4.8k 1.0× 1.7k 0.9× 1.9k 1.0× 4.2k 2.3× 152 19.5k
Tomoki Chiba Japan 51 13.7k 1.1× 5.7k 1.2× 3.2k 1.7× 2.0k 1.1× 2.0k 1.1× 141 20.7k
Roberta A. Gottlieb United States 77 12.2k 1.0× 5.5k 1.1× 2.2k 1.1× 2.1k 1.1× 1.6k 0.9× 215 20.2k
Catherine Brenner France 57 10.9k 0.9× 2.6k 0.5× 1.4k 0.7× 1.1k 0.6× 1.8k 1.0× 139 16.4k
Carlotta Giorgi Italy 68 11.4k 0.9× 2.7k 0.6× 2.8k 1.4× 1.9k 1.0× 1.2k 0.7× 180 16.9k
Mathieu Laplante Canada 36 8.9k 0.7× 3.3k 0.7× 1.6k 0.8× 3.8k 2.0× 1.6k 0.9× 78 15.1k
Quan Chen China 58 7.6k 0.6× 4.0k 0.8× 1.3k 0.7× 1.3k 0.7× 1.1k 0.6× 266 12.4k
Jorge Moscat United States 76 12.8k 1.0× 4.2k 0.9× 2.8k 1.4× 1.4k 0.8× 2.6k 1.4× 182 18.3k
Guo-Fan Cao China 11 7.9k 0.6× 7.5k 1.5× 2.1k 1.1× 1.6k 0.8× 1.2k 0.7× 17 14.4k

Countries citing papers authored by Shigeomi Shimizu

Since Specialization
Citations

This map shows the geographic impact of Shigeomi Shimizu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shigeomi Shimizu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shigeomi Shimizu more than expected).

Fields of papers citing papers by Shigeomi Shimizu

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shigeomi Shimizu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shigeomi Shimizu. The network helps show where Shigeomi Shimizu may publish in the future.

Co-authorship network of co-authors of Shigeomi Shimizu

This figure shows the co-authorship network connecting the top 25 collaborators of Shigeomi Shimizu. A scholar is included among the top collaborators of Shigeomi Shimizu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shigeomi Shimizu. Shigeomi Shimizu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Honda, Shinya, Satoko Arakawa, Satoru Torii, et al.. (2025). Optineurin is an adaptor protein for ubiquitinated substrates in Golgi membrane-associated degradation. Nature Communications. 16(1). 8966–8966.
2.
Honda, Shinya, Min Kyoung Shin, Kei Watase, et al.. (2024). Subcellular localization and ER-mediated cytotoxic function of α1A and α1ACT in spinocerebellar ataxia type 6. Biochemical and Biophysical Research Communications. 695. 149481–149481. 2 indexed citations
3.
Torii, Satoru, et al.. (2024). Presence of Gut Microbiota Worsens D‐Galactosamine and Lipopolysaccharide‐Induced Hepatic Injury in Mice. Genes to Cells. 30(1). e13183–e13183. 1 indexed citations
4.
Hasegawa, Tatsuya, Masaya Nakashima, Makiko Goto, et al.. (2024). Alternative autophagy dampens UVB-induced NLRP3 inflammasome activation in human keratinocytes. Journal of Biological Chemistry. 300(4). 107173–107173. 3 indexed citations
5.
Torii, Satoru, Satoko Arakawa, Shigeto Sato, et al.. (2023). Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2. EMBO Molecular Medicine. 15(9). e17451–e17451. 5 indexed citations
6.
Arakawa, Satoko, Takehiro Suzuki, Hiroyuki Hara, et al.. (2023). Biogenesis of fibrils requires C‐mannosylation of PMEL. FEBS Journal. 290(22). 5373–5394. 2 indexed citations
7.
Torii, Satoru, et al.. (2023). Uncovering the Localization and Function of a Novel Read-Through Transcript ‘TOMM40-APOE’. Cells. 13(1). 69–69. 2 indexed citations
8.
Arakawa, Satoko, et al.. (2023). An Overview of Golgi Membrane-Associated Degradation (GOMED) and Its Detection Methods. Cells. 12(24). 2817–2817. 1 indexed citations
9.
Kato, Hiroaki, Kohki Okabe, Masato Miyake, et al.. (2020). ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue. Life Science Alliance. 3(3). e201900576–e201900576. 29 indexed citations
10.
Yamaguchi, Hirofumi, Shinya Honda, Satoru Torii, et al.. (2020). Wipi3 is essential for alternative autophagy and its loss causes neurodegeneration. Nature Communications. 11(1). 5311–5311. 37 indexed citations
11.
Muraoka, Naoto, Fumiya Tamura, Hidenori Kojima, et al.. (2019). Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming. Nature Communications. 10(1). 674–674. 76 indexed citations
12.
Kozaki, Tatsuya, Jun Komano, Michihiro Takahama, et al.. (2017). Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response. Proceedings of the National Academy of Sciences. 114(10). 2681–2686. 53 indexed citations
13.
Kanemoto, Kazuya, et al.. (2017). Rhodium-catalyzed odorless synthesis of diaryl sulfides from borylarenes and S-aryl thiosulfonates. Chemical Communications. 53(77). 10640–10643. 61 indexed citations
14.
Yamaguchi, Hirofumi, Satoko Arakawa, Toku Kanaseki, et al.. (2016). Golgi membrane‐associated degradation pathway in yeast and mammals. The EMBO Journal. 35(18). 1991–2007. 73 indexed citations
15.
Narita, Masako, Andrew Young, Satoko Arakawa, et al.. (2011). Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes. Science. 332(6032). 966–970. 459 indexed citations breakdown →
16.
Young, Andrew, Masako Narita, Manuela Ferreira, et al.. (2009). Autophagy mediates the mitotic senescence transition. Genes & Development. 23(7). 798–803. 836 indexed citations breakdown →
17.
Fujihashi, M., et al.. (2007). Crystal structure of human cyclophilin D in complex with its inhibitor, cyclosporin A at 0.96‐Å resolution. Proteins Structure Function and Bioinformatics. 70(4). 1635–1639. 52 indexed citations
18.
Tsuruta, Fuminori, Jun Sunayama, Yasunori Mori, et al.. (2004). JNK promotes Bax translocation to mitochondria through phosphorylation of 14‐3‐3 proteins. The EMBO Journal. 23(8). 1889–1899. 460 indexed citations
19.
Shimizu, Shigeomi, Toshihiro Funatsu, Hiroshi Tamagawa, et al.. (2003). BH4-domain peptide from Bcl-xL exerts anti-apoptotic activity in vivo. Oncogene. 22(52). 8432–8440. 87 indexed citations
20.
Yonekura, Takeo, Kazuyasu Nakao, Nobuhiro Fujita, et al.. (1991). A Case Report of Multiple Cancers in Colon and Rectum Accompanied with Gastric Cancer.. The Japanese Journal of Gastroenterological Surgery. 24(11). 2814–2818.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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