Binghui Shen

9.8k total citations
145 papers, 6.6k citations indexed

About

Binghui Shen is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Binghui Shen has authored 145 papers receiving a total of 6.6k indexed citations (citations by other indexed papers that have themselves been cited), including 126 papers in Molecular Biology, 27 papers in Cancer Research and 24 papers in Oncology. Recurrent topics in Binghui Shen's work include DNA Repair Mechanisms (88 papers), CRISPR and Genetic Engineering (27 papers) and DNA and Nucleic Acid Chemistry (20 papers). Binghui Shen is often cited by papers focused on DNA Repair Mechanisms (88 papers), CRISPR and Genetic Engineering (27 papers) and DNA and Nucleic Acid Chemistry (20 papers). Binghui Shen collaborates with scholars based in United States, China and United Kingdom. Binghui Shen's co-authors include Li Zheng, Junzhuan Qiu, John A. Tainer, Mian Zhou, David J. Hosfield, Huifang Dai, Zhigang Guo, L. David Finger, Purnima Singh and B.R. Chapados and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Binghui Shen

142 papers receiving 6.5k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Binghui Shen United States 47 5.9k 918 897 819 411 145 6.6k
Karen M. Vásquez United States 48 5.6k 1.0× 736 0.8× 1.0k 1.1× 695 0.8× 418 1.0× 124 6.7k
Orlando D. Schärer United States 42 6.7k 1.1× 1.0k 1.1× 1.3k 1.5× 926 1.1× 446 1.1× 97 7.3k
Michael M. Seidman United States 48 6.0k 1.0× 998 1.1× 1.2k 1.4× 888 1.1× 680 1.7× 147 6.8k
J. Pablo Radicella France 38 4.3k 0.7× 671 0.7× 1.1k 1.2× 632 0.8× 564 1.4× 98 5.3k
Grigory L. Dianov United Kingdom 50 6.6k 1.1× 2.0k 2.2× 1.5k 1.7× 774 0.9× 438 1.1× 117 7.4k
Kaoru Sugasawa Japan 47 7.7k 1.3× 1.5k 1.6× 1.3k 1.5× 1.1k 1.3× 445 1.1× 126 8.3k
John J. Turchi United States 40 4.0k 0.7× 1.6k 1.7× 792 0.9× 401 0.5× 242 0.6× 103 4.7k
Graham Dellaire Canada 43 4.9k 0.8× 865 0.9× 551 0.6× 597 0.7× 409 1.0× 123 6.2k
Xiaohua Wu United States 52 6.4k 1.1× 1.5k 1.6× 1.2k 1.3× 964 1.2× 1.1k 2.8× 135 7.7k
Yuan Chen United States 36 3.8k 0.6× 1.1k 1.2× 679 0.8× 293 0.4× 257 0.6× 121 4.7k

Countries citing papers authored by Binghui Shen

Since Specialization
Citations

This map shows the geographic impact of Binghui Shen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Binghui Shen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Binghui Shen more than expected).

Fields of papers citing papers by Binghui Shen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Binghui Shen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Binghui Shen. The network helps show where Binghui Shen may publish in the future.

Co-authorship network of co-authors of Binghui Shen

This figure shows the co-authorship network connecting the top 25 collaborators of Binghui Shen. A scholar is included among the top collaborators of Binghui Shen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Binghui Shen. Binghui Shen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Wang, Yixing, Chen Wang, Jennifer Jossart, et al.. (2025). Discovery and Characterization of Small Molecule Inhibitors Targeting Exonuclease 1 for Homologous Recombination-Deficient Cancer Therapy. ACS Chemical Biology. 20(6). 1258–1272.
2.
Shen, Changxian, Tiantian Cui, Linlin Yang, et al.. (2025). KRAS-induced STN1 (OBFC1) promotes proper CTC1–STN1–TEN1 complex-independent DNA double-strand break repair and cell cycle checkpoint maintenance in pancreatic cancer. Nucleic Acids Research. 53(18). 1 indexed citations
3.
Zhou, Mian, et al.. (2024). Structure-specific nucleases in genome dynamics and strategies for targeting cancers. Journal of Molecular Cell Biology. 16(5). 1 indexed citations
4.
Wang, Yingying, Anthony P. Fernandez, Bing Liu, et al.. (2024). EGFR-mediated HSP70 phosphorylation facilitates PCNA association with chromatin and DNA replication. Nucleic Acids Research. 52(21). 13057–13072. 2 indexed citations
5.
Liu, Wenpeng, Piotr Polaczek, Yuan Meng, et al.. (2023). FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability. Nucleic Acids Research. 51(17). 9144–9165. 13 indexed citations
6.
Abeywardana, Tharindumala, et al.. (2022). Structure-specific nucleases: role in Okazaki fragment maturation. Trends in Genetics. 38(8). 793–796. 2 indexed citations
7.
Tsai, Yafang, et al.. (2022). Okazaki fragment maturation: DNA flap dynamics for cell proliferation and survival. Trends in Cell Biology. 33(3). 221–234. 23 indexed citations
8.
Singh, Amanpreet, Yajing Zhou, Mian Zhou, et al.. (2021). Error-prone, stress-induced 3′ flap–based Okazaki fragment maturation supports cell survival. Science. 374(6572). 1252–1258. 10 indexed citations
9.
Liu, Bing, et al.. (2021). Genomic instability as a major mechanism for acquired resistance to EGFR tyrosine kinase inhibitors in cancer. Protein & Cell. 13(2). 82–89. 10 indexed citations
10.
Chu, Fong‐Fong, R. Steven Esworthy, Binghui Shen, & James H. Doroshow. (2020). Role of the microbiota in ileitis of a mouse model of inflammatory bowel disease—Glutathione peroxide isoenzymes 1 and 2‐double knockout mice on a C57BL background. MicrobiologyOpen. 9(10). e1107–e1107. 6 indexed citations
11.
Thakar, Tanay, Wendy Leung, Claudia M. Nicolae, et al.. (2020). Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly. Nature Communications. 11(1). 2147–2147. 90 indexed citations
12.
Meng, Yuan, Changwei Liu, Lei Shen, et al.. (2019). TRAF6 mediates human DNA2 polyubiquitination and nuclear localization to maintain nuclear genome integrity. Nucleic Acids Research. 47(14). 7564–7579. 20 indexed citations
13.
Zheng, Li, Yuan Meng, Judith L. Campbell, & Binghui Shen. (2019). Multiple roles of DNA2 nuclease/helicase in DNA metabolism, genome stability and human diseases. Nucleic Acids Research. 48(1). 16–35. 75 indexed citations
14.
Palma, Anita, Eva Malacaria, Li Zheng, et al.. (2019). RAD51 and mitotic function of mus81 are essential for recovery from low-dose of camptothecin in the absence of the WRN exonuclease. Nucleic Acids Research. 47(13). 6796–6810. 9 indexed citations
15.
Li, Zhengke, Bochao Liu, Weiwei Jin, et al.. (2018). hDNA 2 nuclease/helicase promotes centromeric DNA replication and genome stability. The EMBO Journal. 37(14). 46 indexed citations
16.
Chang, Lufen, Hu Zhou, Jing Gao, et al.. (2018). ITCH nuclear translocation and H1.2 polyubiquitination negatively regulate the DNA damage response. Nucleic Acids Research. 47(2). 824–842. 18 indexed citations
17.
Xu, Hong, Rongyi Shi, Jiahui Cheng, et al.. (2018). Structural basis of 5′ flap recognition and protein–protein interactions of human flap endonuclease 1. Nucleic Acids Research. 46(21). 11315–11325. 19 indexed citations
18.
Shouse, Geoffrey, et al.. (2013). B56γ Tumor-Associated Mutations Provide New Mechanisms for B56γ-PP2A Tumor Suppressor Activity. Molecular Cancer Research. 11(9). 995–1003. 27 indexed citations
19.
Singh, Purnima, Ming Yang, Huifang Dai, et al.. (2008). Overexpression and Hypomethylation of Flap Endonuclease 1 Gene in Breast and Other Cancers. Molecular Cancer Research. 6(11). 1710–1717. 104 indexed citations
20.
Qiu, Junzhuan, Ying Qian, Peter Frank, Ulrike Wintersberger, & Binghui Shen. (1999). Saccharomyces cerevisiae RNase H(35) Functions in RNA Primer Removal during Lagging-Strand DNA Synthesis, Most Efficiently in Cooperation with Rad27 Nuclease. Molecular and Cellular Biology. 19(12). 8361–8371. 134 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Karen M. Vásquez Breakdown of academic impact, for papers by Orlando D. Schärer Breakdown of academic impact, for papers by Michael M. Seidman Breakdown of academic impact, for papers by J. Pablo Radicella Breakdown of academic impact, for papers by Grigory L. Dianov Breakdown of academic impact, for papers by Kaoru Sugasawa Breakdown of academic impact, for papers by John J. Turchi Breakdown of academic impact, for papers by Graham Dellaire Breakdown of academic impact, for papers by Xiaohua Wu Breakdown of academic impact, for papers by Yuan Chen
Rankless by CCL
2026